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Items: 1 to 50 of 156

1.

Predicting the Effectiveness of Hepatitis C Virus Neutralizing Antibodies by Bioinformatic Analysis of Conserved Epitope Residues Using Public Sequence Data.

Cowton VM, Singer JB, Gifford RJ, Patel AH.

Front Immunol. 2018 Jun 27;9:1470. doi: 10.3389/fimmu.2018.01470. eCollection 2018.

2.

Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors.

López-Camacho C, Abbink P, Larocca RA, Dejnirattisai W, Boyd M, Badamchi-Zadeh A, Wallace ZR, Doig J, Velazquez RS, Neto RDL, Coelho DF, Kim YC, Donald CL, Owsianka A, De Lorenzo G, Kohl A, Gilbert SC, Dorrell L, Mongkolsapaya J, Patel AH, Screaton GR, Barouch DH, Hill AVS, Reyes-Sandoval A.

Nat Commun. 2018 Jun 22;9(1):2441. doi: 10.1038/s41467-018-04859-5.

3.

Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice.

Krapchev VB, Rychłowska M, Chmielewska A, Zimmer K, Patel AH, Bieńkowska-Szewczyk K.

Virology. 2018 Jun;519:33-41. doi: 10.1016/j.virol.2018.03.026. Epub 2018 Apr 6.

4.

Quality and readability of online patient information regarding sclerotherapy for venous malformations.

Pass JH, Patel AH, Stuart S, Barnacle AM, Patel PA.

Pediatr Radiol. 2018 May;48(5):708-714. doi: 10.1007/s00247-018-4074-3. Epub 2018 Feb 2.

PMID:
29396791
5.

Dengue Virus Capsid Interacts with DDX3X-A Potential Mechanism for Suppression of Antiviral Functions in Dengue Infection.

Kumar R, Singh N, Abdin MZ, Patel AH, Medigeshi GR.

Front Cell Infect Microbiol. 2018 Jan 17;7:542. doi: 10.3389/fcimb.2017.00542. eCollection 2017.

6.

Immobilization by Surface Conjugation of Cyclic Peptides for Effective Mimicry of the HCV-Envelope E2 Protein as a Strategy toward Synthetic Vaccines.

Meuleman TJ, Dunlop JI, Owsianka AM, van de Langemheen H, Patel AH, Liskamp RMJ.

Bioconjug Chem. 2018 Apr 18;29(4):1091-1101. doi: 10.1021/acs.bioconjchem.7b00755. Epub 2018 Feb 19.

7.

Efficacy of generic oral directly acting agents in patients with hepatitis C virus infection.

Gupta S, Rout G, Patel AH, Mahanta M, Kalra N, Sahu P, Sethia R, Agarwal A, Ranjan G, Kedia S, Acharya SK, Nayak B, Shalimar.

J Viral Hepat. 2018 Jul;25(7):771-778. doi: 10.1111/jvh.12870. Epub 2018 Mar 22.

PMID:
29377464
8.

Development and characterization of a human monoclonal antibody targeting the N-terminal region of hepatitis C virus envelope glycoprotein E1.

Mesalam AA, Desombere I, Farhoudi A, Van Houtte F, Verhoye L, Ball J, Dubuisson J, Foung SKH, Patel AH, Persson MAA, Leroux-Roels G, Meuleman P.

Virology. 2018 Jan 15;514:30-41. doi: 10.1016/j.virol.2017.10.019. Epub 2017 Nov 10.

9.

A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo.

Desombere I, Mesalam AA, Urbanowicz RA, Van Houtte F, Verhoye L, Keck ZY, Farhoudi A, Vercauteren K, Weening KE, Baumert TF, Patel AH, Foung SKH, Ball J, Leroux-Roels G, Meuleman P.

Antiviral Res. 2017 Dec;148:53-64. doi: 10.1016/j.antiviral.2017.10.015. Epub 2017 Oct 23.

10.

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C.

Naiyer MM, Cassidy SA, Magri A, Cowton V, Chen K, Mansour S, Kranidioti H, Mbirbindi B, Rettman P, Harris S, Fanning LJ, Mulder A, Claas FHJ, Davidson AD, Patel AH, Purbhoo MA, Khakoo SI.

Sci Immunol. 2017 Sep 15;2(15). pii: eaal5296. doi: 10.1126/sciimmunol.aal5296.

PMID:
28916719
11.

Long-term outcomes of transjugular intrahepatic portosystemic shunt in Indian patients with Budd-Chiari syndrome.

Shalimar, Gamanagatti SR, Patel AH, Kedia S, Nayak B, Gunjan D, Ranjan G, Paul SB, Acharya SK.

Eur J Gastroenterol Hepatol. 2017 Oct;29(10):1174-1182. doi: 10.1097/MEG.0000000000000945.

PMID:
28763339
12.

Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer.

Heerma van Voss MR, Vesuna F, Bol GM, Meeldijk J, Raman A, Offerhaus GJ, Buerger H, Patel AH, van der Wall E, van Diest PJ, Raman V.

Onco Targets Ther. 2017 Jul 17;10:3501-3513. doi: 10.2147/OTT.S140639. eCollection 2017.

13.

Finite Field Method for Nonlinear Optical Property Prediction Using Rational Function Approximants.

Patel AHG, Mohammed AAK, Limacher PA, Ayers PW.

J Phys Chem A. 2017 Jul 20;121(28):5313-5323. doi: 10.1021/acs.jpca.7b04049. Epub 2017 Jul 6.

PMID:
28632384
14.

Reverse epitope mapping of the E2 glycoprotein in antibody associated hepatitis C virus.

Naik AS, Owsianka A, Palmer BA, O'Halloran CJ, Walsh N, Crosbie O, Kenny-Walsh E, Patel AH, Fanning LJ.

PLoS One. 2017 May 30;12(5):e0175349. doi: 10.1371/journal.pone.0175349. eCollection 2017.

15.

Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.

Vasiliauskaite I, Owsianka A, England P, Khan AG, Cole S, Bankwitz D, Foung SKH, Pietschmann T, Marcotrigiano J, Rey FA, Patel AH, Krey T.

MBio. 2017 May 16;8(3). pii: e00382-17. doi: 10.1128/mBio.00382-17.

16.

Benchmarking pKa prediction methods for Lys115 in acetoacetate decarboxylase.

Liu Y, Patel AHG, Burger SK, Ayers PW.

J Mol Model. 2017 May;23(5):155. doi: 10.1007/s00894-017-3324-x. Epub 2017 Apr 5.

PMID:
28382418
17.

Invasive fungal infections in renal transplant patients: a single center study.

Patel MH, Patel RD, Vanikar AV, Kanodia KV, Suthar KS, Nigam LK, Patel HV, Patel AH, Kute VB, Trivedi HL.

Ren Fail. 2017 Nov;39(1):294-298. doi: 10.1080/0886022X.2016.1268537.

18.

17,β-estradiol inhibits hepatitis C virus mainly by interference with the release phase of its life cycle.

Magri A, Barbaglia MN, Foglia CZ, Boccato E, Burlone ME, Cole S, Giarda P, Grossini E, Patel AH, Minisini R, Pirisi M.

Liver Int. 2017 May;37(5):669-677. doi: 10.1111/liv.13303. Epub 2016 Nov 25.

19.

Anti-envelope antibody responses in individuals at high risk of hepatitis C virus who resist infection.

Swann RE, Mandalou P, Robinson MW, Ow MM, Foung SK, McLauchlan J, Patel AH, Cramp ME.

J Viral Hepat. 2016 Nov;23(11):873-880. doi: 10.1111/jvh.12568. Epub 2016 Jul 13.

20.

Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil.

Donald CL, Brennan B, Cumberworth SL, Rezelj VV, Clark JJ, Cordeiro MT, Freitas de Oliveira França R, Pena LJ, Wilkie GS, Da Silva Filipe A, Davis C, Hughes J, Varjak M, Selinger M, Zuvanov L, Owsianka AM, Patel AH, McLauchlan J, Lindenbach BD, Fall G, Sall AA, Biek R, Rehwinkel J, Schnettler E, Kohl A.

PLoS Negl Trop Dis. 2016 Oct 5;10(10):e0005048. doi: 10.1371/journal.pntd.0005048. eCollection 2016 Oct.

21.

Corrigendum: Exploration of acetanilide derivatives of 1-(ω-phenoxyalkyl)uracils as novel inhibitors of Hepatitis C Virus replication.

Magri A, Ozerov AA, Tunitskaya VL, Valuev-Elliston VT, Wahid A, Pirisi M, Simmonds P, Ivanov AV, Novikov MS, Patel AH.

Sci Rep. 2016 Aug 25;6:31529. doi: 10.1038/srep31529. No abstract available.

22.

The usability of ventilators: a comparative evaluation of use safety and user experience.

Morita PP, Weinstein PB, Flewwelling CJ, Bañez CA, Chiu TA, Iannuzzi M, Patel AH, Shier AP, Cafazzo JA.

Crit Care. 2016 Aug 20;20:263. doi: 10.1186/s13054-016-1431-1.

23.

Communication: Two types of flat-planes conditions in density functional theory.

Yang XD, Patel AH, Miranda-Quintana RA, Heidar-Zadeh F, González-Espinoza CE, Ayers PW.

J Chem Phys. 2016 Jul 21;145(3):031102. doi: 10.1063/1.4958636.

PMID:
27448863
24.

Exploration of acetanilide derivatives of 1-(ω-phenoxyalkyl)uracils as novel inhibitors of Hepatitis C Virus replication.

Magri A, Ozerov AA, Tunitskaya VL, Valuev-Elliston VT, Wahid A, Pirisi M, Simmonds P, Ivanov AV, Novikov MS, Patel AH.

Sci Rep. 2016 Jul 12;6:29487. doi: 10.1038/srep29487. Erratum in: Sci Rep. 2016 Aug 25;6:31529.

25.

Role of Conserved E2 Residue W420 in Receptor Binding and Hepatitis C Virus Infection.

Cowton VM, Angus AGN, Cole SJ, Markopoulou CK, Owsianka A, Dunlop JI, Gardner DE, Krey T, Patel AH.

J Virol. 2016 Jul 27;90(16):7456-7468. doi: 10.1128/JVI.00685-16. Print 2016 Aug 15.

26.

Tracking TCRβ Sequence Clonotype Expansions during Antiviral Therapy Using High-Throughput Sequencing of the Hypervariable Region.

Robinson MW, Hughes J, Wilkie GS, Swann R, Barclay ST, Mills PR, Patel AH, Thomson EC, McLauchlan J.

Front Immunol. 2016 Apr 5;7:131. doi: 10.3389/fimmu.2016.00131. eCollection 2016.

27.

Broad Anti-Hepatitis C Virus (HCV) Antibody Responses Are Associated with Improved Clinical Disease Parameters in Chronic HCV Infection.

Swann RE, Cowton VM, Robinson MW, Cole SJ, Barclay ST, Mills PR, Thomson EC, McLauchlan J, Patel AH.

J Virol. 2016 Apr 14;90(9):4530-4543. doi: 10.1128/JVI.02669-15. Print 2016 May.

28.

Generation and Characterization of Monoclonal Antibodies against a Cyclic Variant of Hepatitis C Virus E2 Epitope 412-422.

Sandomenico A, Leonardi A, Berisio R, Sanguigno L, Focà G, Focà A, Ruggiero A, Doti N, Muscariello L, Barone D, Farina C, Owsianka A, Vitagliano L, Patel AH, Ruvo M.

J Virol. 2016 Jan 27;90(7):3745-59. doi: 10.1128/JVI.02397-15.

29.

Monoclonal anti-envelope antibody AP33 protects humanized mice against a patient-derived hepatitis C virus challenge.

Desombere I, Fafi-Kremer S, Van Houtte F, Pessaux P, Farhoudi A, Heydmann L, Verhoye L, Cole S, McKeating JA, Leroux-Roels G, Baumert TF, Patel AH, Meuleman P.

Hepatology. 2016 Apr;63(4):1120-34. doi: 10.1002/hep.28428. Epub 2016 Feb 22.

PMID:
26710081
30.

Rethinking the old antiviral drug moroxydine: Discovery of novel analogues as anti-hepatitis C virus (HCV) agents.

Magri A, Reilly R, Scalacci N, Radi M, Hunter M, Ripoll M, Patel AH, Castagnolo D.

Bioorg Med Chem Lett. 2015 Nov 15;25(22):5372-6. doi: 10.1016/j.bmcl.2015.09.029. Epub 2015 Sep 12.

PMID:
26428870
31.

Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies.

Fauvelle C, Felmlee DJ, Crouchet E, Lee J, Heydmann L, Lefèvre M, Magri A, Hiet MS, Fofana I, Habersetzer F, Foung SK, Milne R, Patel AH, Vercauteren K, Meuleman P, Zeisel MB, Bartenschlager R, Schuster C, Baumert TF.

Gastroenterology. 2016 Jan;150(1):206-217.e4. doi: 10.1053/j.gastro.2015.09.014. Epub 2015 Sep 25.

PMID:
26404951
32.

In memoriam--Richard M. Elliott (1954-2015).

Brennan B, Weber F, Kormelink R, Schnettler E, Bouloy M, Failloux AB, Weaver SC, Fazakerley JK, Fragkoudis R, Harris M, Barr JN, Palese P, García-Sastre A, Dalziel RG, Dutia BM, Lowen AC, Steel J, Randall RE, Paul Duprex W, Rice CM, Tesh RB, Murphy FA, Ebihara H, Vasconcelos PF, Nunes MR, Fooks AR, Smith GL, Goodfellow I, Pappu HR, Lamb RA, Paterson RG, Higgs S, Vanlandingham DL, Dietzgen RG, Stephen Lodmell J, Nichol ST, Daly J, Ullman DE, Plyusnin A, Plyusnina A, Efstathiou S, Hewson R, Tordo N, Cherry S, Boutell C, Hosie MJ, Murcia PR, Neil JC, Palmarini M, Patel AH, Willett BJ, Kohl A, McLauchlan J.

J Gen Virol. 2015 Aug;96(8):1975-8. doi: 10.1099/jgv.0.000241. No abstract available.

33.

Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection.

Robinson MW, Aranday-Cortes E, Gatherer D, Swann R, Liefhebber JM, Filipe Ada S, Sigruener A, Barclay ST, Mills PR, Patel AH, McLauchlan J.

Liver Int. 2015 Oct;35(10):2256-64. doi: 10.1111/liv.12830. Epub 2015 Apr 7.

34.

Expanding the efficacy of Project UPLIFT: Distance delivery of mindfulness-based depression prevention to people with epilepsy.

Thompson NJ, Patel AH, Selwa LM, Stoll SC, Begley CE, Johnson EK, Fraser RT.

J Consult Clin Psychol. 2015 Apr;83(2):304-313. doi: 10.1037/a0038404. Epub 2014 Dec 15.

35.

Blood-based gene-expression biomarkers of post-traumatic stress disorder among deployed marines: A pilot study.

Tylee DS, Chandler SD, Nievergelt CM, Liu X, Pazol J, Woelk CH, Lohr JB, Kremen WS, Baker DG, Glatt SJ, Tsuang MT; Marine Resiliency Study Investigators.

Psychoneuroendocrinology. 2015 Jan;51:472-94. doi: 10.1016/j.psyneuen.2014.09.024. Epub 2014 Sep 30.

36.

Elevated interferon-stimulated gene transcription in peripheral blood mononuclear cells occurs in patients infected with genotype 1 but not genotype 3 hepatitis C virus.

Robinson MW, Swann R, Sigruener A, Barclay ST, Mills PR, McLauchlan J, Patel AH.

J Viral Hepat. 2015 Apr;22(4):384-90. doi: 10.1111/jvh.12310. Epub 2014 Sep 9.

37.

Diagnostic Utility of the Posttraumatic Stress Disorder (PTSD) Checklist for Identifying Full and Partial PTSD in Active-Duty Military.

Dickstein BD, Weathers FW, Angkaw AC, Nievergelt CM, Yurgil K, Nash WP, Baker DG, Litz BT; Marine Resiliency Study Team.

Assessment. 2015 Jun;22(3):289-97. doi: 10.1177/1073191114548683. Epub 2014 Sep 1.

38.

Non-random escape pathways from a broadly neutralizing human monoclonal antibody map to a highly conserved region on the hepatitis C virus E2 glycoprotein encompassing amino acids 412-423.

Keck ZY, Angus AG, Wang W, Lau P, Wang Y, Gatherer D, Patel AH, Foung SK.

PLoS Pathog. 2014 Aug 14;10(8):e1004297. doi: 10.1371/journal.ppat.1004297. eCollection 2014 Aug.

39.

Modulating innate immunity improves hepatitis C virus infection and replication in stem cell-derived hepatocytes.

Zhou X, Sun P, Lucendo-Villarin B, Angus AG, Szkolnicka D, Cameron K, Farnworth SL, Patel AH, Hay DC.

Stem Cell Reports. 2014 May 29;3(1):204-14. doi: 10.1016/j.stemcr.2014.04.018. eCollection 2014 Jul 8.

40.

Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents.

Xiao F, Fofana I, Heydmann L, Barth H, Soulier E, Habersetzer F, Doffoël M, Bukh J, Patel AH, Zeisel MB, Baumert TF.

PLoS Pathog. 2014 May 15;10(5):e1004128. doi: 10.1371/journal.ppat.1004128. eCollection 2014 May.

41.

Modeling human liver biology using stem cell-derived hepatocytes.

Sun P, Zhou X, Farnworth SL, Patel AH, Hay DC.

Int J Mol Sci. 2013 Nov 6;14(11):22011-21. doi: 10.3390/ijms141122011. Review.

42.

Impact of physiologically based pharmacokinetic modeling and simulation in drug development.

Shardlow CE, Generaux GT, Patel AH, Tai G, Tran T, Bloomer JC.

Drug Metab Dispos. 2013 Dec;41(12):1994-2003. doi: 10.1124/dmd.113.052803. Epub 2013 Sep 5.

43.

Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease.

Robinson MW, McGuinness D, Swann R, Barclay S, Mills PR, Patel AH, McLauchlan J, Shiels PG.

Aging Cell. 2013 Dec;12(6):1141-3. doi: 10.1111/acel.12125. Epub 2013 Aug 12.

44.

Critical review of preclinical approaches to investigate cytochrome p450-mediated therapeutic protein drug-drug interactions and recommendations for best practices: a white paper.

Evers R, Dallas S, Dickmann LJ, Fahmi OA, Kenny JR, Kraynov E, Nguyen T, Patel AH, Slatter JG, Zhang L.

Drug Metab Dispos. 2013 Sep;41(9):1598-609. doi: 10.1124/dmd.113.052225. Epub 2013 Jun 21. Review.

45.

Survival following gamma knife radiosurgery for brain metastasis from breast cancer.

Jaboin JJ, Ferraro DJ, DeWees TA, Rich KM, Chicoine MR, Dowling JL, Mansur DB, Drzymala RE, Simpson JR, Magnuson WJ, Patel AH, Zoberi I.

Radiat Oncol. 2013 May 29;8:131. doi: 10.1186/1748-717X-8-131.

46.

Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer.

Bol GM, Raman V, van der Groep P, Vermeulen JF, Patel AH, van der Wall E, van Diest PJ.

PLoS One. 2013 May 16;8(5):e63548. doi: 10.1371/journal.pone.0063548. Print 2013.

47.

Combined reflectance confocal microscopy/optical coherence tomography imaging for skin burn assessment.

Iftimia N, Ferguson RD, Mujat M, Patel AH, Zhang EZ, Fox W, Rajadhyaksha M.

Biomed Opt Express. 2013 Apr 8;4(5):680-95. doi: 10.1364/BOE.4.000680. Print 2013 May 1.

48.

Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.

Pantua H, Diao J, Ultsch M, Hazen M, Mathieu M, McCutcheon K, Takeda K, Date S, Cheung TK, Phung Q, Hass P, Arnott D, Hongo JA, Matthews DJ, Brown A, Patel AH, Kelley RF, Eigenbrot C, Kapadia SB.

J Mol Biol. 2013 Jun 12;425(11):1899-1914. doi: 10.1016/j.jmb.2013.02.025. Epub 2013 Feb 28.

49.

Cooperativity in virus neutralization by human monoclonal antibodies to two adjacent regions located at the amino terminus of hepatitis C virus E2 glycoprotein.

Keck Z, Wang W, Wang Y, Lau P, Carlsen TH, Prentoe J, Xia J, Patel AH, Bukh J, Foung SK.

J Virol. 2013 Jan;87(1):37-51. doi: 10.1128/JVI.01941-12. Epub 2012 Oct 24.

50.

A rare case of primary otoscleroma of the middle ear.

Kakeri AR, Patel AH.

J Laryngol Otol. 2012 Dec;126(12):1276-7. doi: 10.1017/S0022215112002174. Epub 2012 Oct 4. Review.

PMID:
23034316

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