Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 28

1.

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients.

Papoutsopoulou S, Burkitt MD, Bergey F, England H, Hough R, Schmidt L, Spiller DG, White MHR, Paszek P, Jackson DA, Martins Dos Santos VAP, Sellge G, Pritchard DM, Campbell BJ, Müller W, Probert CS.

Front Immunol. 2019 Sep 11;10:2168. doi: 10.3389/fimmu.2019.02168. eCollection 2019.

2.

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation.

Bagnall J, Boddington C, England H, Brignall R, Downton P, Alsoufi Z, Boyd J, Rowe W, Bennett A, Walker C, Adamson A, Patel NMX, O'Cualain R, Schmidt L, Spiller DG, Jackson DA, Müller W, Muldoon M, White MRH, Paszek P.

Sci Signal. 2018 Jul 24;11(540). pii: eaaf3998. doi: 10.1126/scisignal.aaf3998.

PMID:
30042130
3.

Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level.

Kardyńska M, Paszek A, Śmieja J, Spiller D, Widłak W, White MRH, Paszek P, Kimmel M.

PLoS Comput Biol. 2018 Apr 30;14(4):e1006130. doi: 10.1371/journal.pcbi.1006130. eCollection 2018 Apr.

4.

Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells.

Brignall R, Cauchy P, Bevington SL, Gorman B, Pisco AO, Bagnall J, Boddington C, Rowe W, England H, Rich K, Schmidt L, Dyer NP, Travis MA, Ott S, Jackson DA, Cockerill PN, Paszek P.

J Immunol. 2017 Oct 15;199(8):2652-2667. doi: 10.4049/jimmunol.1602033. Epub 2017 Sep 13.

5.

Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation.

Phillips NE, Manning CS, Pettini T, Biga V, Marinopoulou E, Stanley P, Boyd J, Bagnall J, Paszek P, Spiller DG, White MR, Goodfellow M, Galla T, Rattray M, Papalopulu N.

Elife. 2016 Oct 4;5. pii: e16118. doi: 10.7554/eLife.16118.

6.

Anti-inflammatory effects of infliximab in mice are independent of tumour necrosis factor α neutralization.

Assas BM, Levison SE, Little M, England H, Battrick L, Bagnall J, McLaughlin JT, Paszek P, Else KJ, Pennock JL.

Clin Exp Immunol. 2017 Feb;187(2):225-233. doi: 10.1111/cei.12872. Epub 2016 Nov 23.

7.

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.

Daniels MJ, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth SJ, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D.

Nat Commun. 2016 Aug 11;7:12504. doi: 10.1038/ncomms12504.

8.

Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states.

Adamson A, Boddington C, Downton P, Rowe W, Bagnall J, Lam C, Maya-Mendoza A, Schmidt L, Harper CV, Spiller DG, Rand DA, Jackson DA, White MR, Paszek P.

Nat Commun. 2016 Jul 6;7:12057. doi: 10.1038/ncomms12057.

9.

Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging.

Diamond C, Bagnall J, Spiller DG, White MR, Mortellaro A, Paszek P, Brough D.

Methods Mol Biol. 2016;1417:75-88. doi: 10.1007/978-1-4939-3566-6_4.

PMID:
27221482
10.

Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation.

Ankers JM, Awais R, Jones NA, Boyd J, Ryan S, Adamson AD, Harper CV, Bridge L, Spiller DG, Jackson DA, Paszek P, Sée V, White MR.

Elife. 2016 May 17;5. pii: e10473. doi: 10.7554/eLife.10473.

11.

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.

Martín-Sánchez F, Diamond C, Zeitler M, Gomez AI, Baroja-Mazo A, Bagnall J, Spiller D, White M, Daniels MJ, Mortellaro A, Peñalver M, Paszek P, Steringer JP, Nickel W, Brough D, Pelegrín P.

Cell Death Differ. 2016 Jul;23(7):1219-31. doi: 10.1038/cdd.2015.176. Epub 2016 Feb 12.

12.

Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

Bagnall J, Boddington C, Boyd J, Brignall R, Rowe W, Jones NA, Schmidt L, Spiller DG, White MR, Paszek P.

Integr Biol (Camb). 2015 Jun;7(6):713-25. doi: 10.1039/c5ib00067j. Epub 2015 May 20.

PMID:
25990200
13.

From measuring noise toward integrated single-cell biology.

Paszek P.

Front Genet. 2014 Nov 19;5:408. doi: 10.3389/fgene.2014.00408. eCollection 2014. No abstract available.

14.

A method of ‘speed coefficients’ for biochemical model reduction applied to the NF-κB system.

West S, Bridge LJ, White MR, Paszek P, Biktashev VN.

J Math Biol. 2015 Feb;70(3):591-620.

15.

A systematic survey of the response of a model NF-κB signalling pathway to TNFα stimulation.

Wang Y, Paszek P, Horton CA, Yue H, White MR, Kell DB, Muldoon MR, Broomhead DS.

J Theor Biol. 2012 Mar 21;297:137-47. doi: 10.1016/j.jtbi.2011.12.014. Epub 2011 Dec 23.

16.

Interactions among oscillatory pathways in NF-kappa B signaling.

Wang Y, Paszek P, Horton CA, Kell DB, White MR, Broomhead DS, Muldoon MR.

BMC Syst Biol. 2011 Feb 3;5:23. doi: 10.1186/1752-0509-5-23.

17.

Oscillatory control of signalling molecules.

Paszek P, Jackson DA, White MR.

Curr Opin Genet Dev. 2010 Dec;20(6):670-6. doi: 10.1016/j.gde.2010.08.004. Epub 2010 Sep 17. Review.

PMID:
20850963
18.

Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells.

Turner DA, Paszek P, Woodcock DJ, Nelson DE, Horton CA, Wang Y, Spiller DG, Rand DA, White MR, Harper CV.

J Cell Sci. 2010 Aug 15;123(Pt 16):2834-43. doi: 10.1242/jcs.069641. Epub 2010 Jul 27.

19.

Population robustness arising from cellular heterogeneity.

Paszek P, Ryan S, Ashall L, Sillitoe K, Harper CV, Spiller DG, Rand DA, White MR.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11644-9. doi: 10.1073/pnas.0913798107. Epub 2010 Jun 7.

20.

Dynamic organisation of prolactin gene expression in living pituitary tissue.

Harper CV, Featherstone K, Semprini S, Friedrichsen S, McNeilly J, Paszek P, Spiller DG, McNeilly AS, Mullins JJ, Davis JR, White MR.

J Cell Sci. 2010 Feb 1;123(Pt 3):424-30. doi: 10.1242/jcs.060434.

21.

Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription.

Ashall L, Horton CA, Nelson DE, Paszek P, Harper CV, Sillitoe K, Ryan S, Spiller DG, Unitt JF, Broomhead DS, Kell DB, Rand DA, Sée V, White MR.

Science. 2009 Apr 10;324(5924):242-6. doi: 10.1126/science.1164860.

22.

Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling.

Lipniacki T, Puszynski K, Paszek P, Brasier AR, Kimmel M.

BMC Bioinformatics. 2007 Oct 9;8:376.

23.
24.

Stochastic regulation in early immune response.

Lipniacki T, Paszek P, Brasier AR, Luxon BA, Kimmel M.

Biophys J. 2006 Feb 1;90(3):725-42. Epub 2005 Nov 11.

25.

Transcriptional stochasticity in gene expression.

Lipniacki T, Paszek P, Marciniak-Czochra A, Brasier AR, Kimmel M.

J Theor Biol. 2006 Jan 21;238(2):348-67. Epub 2005 Jul 21.

PMID:
16039671
26.

Stochastic effects of multiple regulators on expression profiles in eukaryotes.

Paszek P, Lipniacki T, Brasier AR, Tian B, Nowak DE, Kimmel M.

J Theor Biol. 2005 Apr 7;233(3):423-33. Epub 2004 Dec 8.

PMID:
15652150
27.

Mathematical model of NF-kappaB regulatory module.

Lipniacki T, Paszek P, Brasier AR, Luxon B, Kimmel M.

J Theor Biol. 2004 May 21;228(2):195-215.

PMID:
15094015
28.

Diagnose progressive encephalopathy applying the rough set theory.

Wakulicz-Deja A, Paszek P.

Int J Med Inform. 1997 Sep;46(2):119-27.

PMID:
9315501

Supplemental Content

Loading ...
Support Center