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Items: 11

1.

Glucose Acutely Reduces Cytosolic and Mitochondrial H2O2 in Rat Pancreatic Beta Cells.

Deglasse JP, Roma LP, Pastor-Flores D, Gilon P, Dick TP, Jonas JC.

Antioxid Redox Signal. 2019 Jan 20;30(3):297-313. doi: 10.1089/ars.2017.7287. Epub 2018 Jun 14.

PMID:
29756464
2.

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.

Cabezas-Wallscheid N, Buettner F, Sommerkamp P, Klimmeck D, Ladel L, Thalheimer FB, Pastor-Flores D, Roma LP, Renders S, Zeisberger P, Przybylla A, Schönberger K, Scognamiglio R, Altamura S, Florian CM, Fawaz M, Vonficht D, Tesio M, Collier P, Pavlinic D, Geiger H, Schroeder T, Benes V, Dick TP, Rieger MA, Stegle O, Trumpp A.

Cell. 2017 May 18;169(5):807-823.e19. doi: 10.1016/j.cell.2017.04.018. Epub 2017 May 4.

3.

Monitoring yeast mitochondria with peroxiredoxin-based redox probes: the influence of oxygen and glucose availability.

Pastor-Flores D, Becker K, Dick TP.

Interface Focus. 2017 Apr 6;7(2):20160143. doi: 10.1098/rsfs.2016.0143.

4.

An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms.

Arencibia JM, Fröhner W, Krupa M, Pastor-Flores D, Merker P, Oellerich T, Neimanis S, Schmithals C, Köberle V, Süß E, Zeuzem S, Stark H, Piiper A, Odadzic D, Schulze JO, Biondi RM.

ACS Chem Biol. 2017 Feb 17;12(2):564-573. doi: 10.1021/acschembio.6b00827. Epub 2017 Jan 13.

PMID:
28045490
5.

Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes.

Morgan B, Van Laer K, Owusu TN, Ezeriņa D, Pastor-Flores D, Amponsah PS, Tursch A, Dick TP.

Nat Chem Biol. 2016 Jun;12(6):437-43. doi: 10.1038/nchembio.2067. Epub 2016 Apr 18.

PMID:
27089028
6.

A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems.

Dóka É, Pader I, Bíró A, Johansson K, Cheng Q, Ballagó K, Prigge JR, Pastor-Flores D, Dick TP, Schmidt EE, Arnér ES, Nagy P.

Sci Adv. 2016 Jan 22;2(1):e1500968. doi: 10.1126/sciadv.1500968. eCollection 2016 Jan.

7.

A click chemistry approach identifies target proteins of xanthohumol.

Brodziak-Jarosz L, Fujikawa Y, Pastor-Flores D, Kasikci S, Jirásek P, Pitzl S, Owen RW, Klika KD, Gerhäuser C, Amslinger S, Dick TP.

Mol Nutr Food Res. 2016 Apr;60(4):737-48. doi: 10.1002/mnfr.201500613. Epub 2016 Mar 11.

PMID:
26748658
8.

Lipid regulators of Pkh2 in Candida albicans, the protein kinase ortholog of mammalian PDK1.

Pastor-Flores D, Schulze JO, Bahí A, Süß E, Casamayor A, Biondi RM.

Biochim Biophys Acta. 2016 Mar;1861(3):249-59. doi: 10.1016/j.bbalip.2015.12.016. Epub 2015 Dec 29.

PMID:
26743850
9.

Depletion of yeast PDK1 orthologs triggers a stress-like transcriptional response.

Pastor-Flores D, Ferrer-Dalmau J, Bahí A, Boleda M, Biondi RM, Casamayor A.

BMC Genomics. 2015 Sep 21;16:719. doi: 10.1186/s12864-015-1903-8.

10.

PIF-pocket as a target for C. albicans Pkh selective inhibitors.

Pastor-Flores D, Schulze JO, Bahí A, Giacometti R, Ferrer-Dalmau J, Passeron S, Engel M, Süss E, Casamayor A, Biondi RM.

ACS Chem Biol. 2013 Oct 18;8(10):2283-92. doi: 10.1021/cb400452z. Epub 2013 Aug 22.

PMID:
23911092
11.

AGC protein kinases: from structural mechanism of regulation to allosteric drug development for the treatment of human diseases.

Arencibia JM, Pastor-Flores D, Bauer AF, Schulze JO, Biondi RM.

Biochim Biophys Acta. 2013 Jul;1834(7):1302-21. doi: 10.1016/j.bbapap.2013.03.010. Epub 2013 Mar 21. Review.

PMID:
23524293

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