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Items: 29

1.

SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.

Xue Y, Meehan B, Fu Z, Wang XQD, Fiset PO, Rieker R, Levins C, Kong T, Zhu X, Morin G, Skerritt L, Herpel E, Venneti S, Martinez D, Judkins AR, Jung S, Camilleri-Broet S, Gonzalez AV, Guiot MC, Lockwood WW, Spicer JD, Agaimy A, Pastor WA, Dostie J, Rak J, Foulkes WD, Huang S.

Nat Commun. 2019 Feb 4;10(1):557. doi: 10.1038/s41467-019-08380-1.

2.

The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation.

Chen D, Liu W, Zimmerman J, Pastor WA, Kim R, Hosohama L, Ho J, Aslanyan M, Gell JJ, Jacobsen SE, Clark AT.

Cell Rep. 2018 Dec 26;25(13):3591-3602.e5. doi: 10.1016/j.celrep.2018.12.011.

3.

TFAP2C regulates transcription in human naive pluripotency by opening enhancers.

Pastor WA, Liu W, Chen D, Ho J, Kim R, Hunt TJ, Lukianchikov A, Liu X, Polo JM, Jacobsen SE, Clark AT.

Nat Cell Biol. 2018 May;20(5):553-564. doi: 10.1038/s41556-018-0089-0. Epub 2018 Apr 25.

4.

Correction: In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.

Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M.

Elife. 2017 Aug 31;6. pii: e30948. doi: 10.7554/eLife.30948. No abstract available.

5.

Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling.

Li X, Yue X, Pastor WA, Lin L, Georges R, Chavez L, Evans SM, Rao A.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):E8267-E8276. doi: 10.1073/pnas.1617802113. Epub 2016 Dec 5.

6.

TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells.

Tsagaratou A, González-Avalos E, Rautio S, Scott-Browne JP, Togher S, Pastor WA, Rothenberg EV, Chavez L, Lähdesmäki H, Rao A.

Nat Immunol. 2017 Jan;18(1):45-53. doi: 10.1038/ni.3630. Epub 2016 Nov 21.

7.

Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin.

Li S, Yen L, Pastor WA, Johnston JB, Du J, Shew CJ, Liu W, Ho J, Stender B, Clark AT, Burlingame AL, Daxinger L, Patel DJ, Jacobsen SE.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5108-16. doi: 10.1073/pnas.1609709113. Epub 2016 Aug 15.

8.

Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes.

Harris CJ, Husmann D, Liu W, Kasmi FE, Wang H, Papikian A, Pastor WA, Moissiard G, Vashisht AA, Dangl JL, Wohlschlegel JA, Jacobsen SE.

PLoS Genet. 2016 May 12;12(5):e1005998. doi: 10.1371/journal.pgen.1005998. eCollection 2016 May.

9.

Control of Foxp3 stability through modulation of TET activity.

Yue X, Trifari S, Äijö T, Tsagaratou A, Pastor WA, Zepeda-Martínez JA, Lio CW, Li X, Huang Y, Vijayanand P, Lähdesmäki H, Rao A.

J Exp Med. 2016 Mar 7;213(3):377-97. doi: 10.1084/jem.20151438. Epub 2016 Feb 22.

10.

Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory.

Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT.

Cell Stem Cell. 2016 Mar 3;18(3):323-329. doi: 10.1016/j.stem.2016.01.019. Epub 2016 Feb 4.

11.

MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation.

Manakov SA, Pezic D, Marinov GK, Pastor WA, Sachidanandam R, Aravin AA.

Cell Rep. 2015 Aug 25;12(8):1234-43. doi: 10.1016/j.celrep.2015.07.036. Epub 2015 Aug 13.

12.

Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis.

Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L, Rao A.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4236-45. doi: 10.1073/pnas.1510510112. Epub 2015 Jul 21.

13.

Erratum: MORC1 represses transposable elements in the mouse male germline.

Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE.

Nat Commun. 2015 Jul 10;6:7604. doi: 10.1038/ncomms8604. No abstract available.

14.

In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.

Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M.

Elife. 2015 Apr 7;4:e06205. doi: 10.7554/eLife.06205. Erratum in: Elife. 2017 Aug 31;6:.

15.

TET proteins and 5-methylcytosine oxidation in hematological cancers.

Ko M, An J, Pastor WA, Koralov SB, Rajewsky K, Rao A.

Immunol Rev. 2015 Jan;263(1):6-21. doi: 10.1111/imr.12239. Review.

16.

MORC1 represses transposable elements in the mouse male germline.

Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE.

Nat Commun. 2014 Dec 12;5:5795. doi: 10.1038/ncomms6795. Erratum in: Nat Commun. 2015;6:7604.

17.

Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea.

Chavez L, Huang Y, Luong K, Agarwal S, Iyer LM, Pastor WA, Hench VK, Frazier-Bowers SA, Korol E, Liu S, Tahiliani M, Wang Y, Clark TA, Korlach J, Pukkila PJ, Aravind L, Rao A.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):E5149-58. doi: 10.1073/pnas.1419513111. Epub 2014 Nov 18.

18.

Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers.

Moissiard G, Bischof S, Husmann D, Pastor WA, Hale CJ, Yen L, Stroud H, Papikian A, Vashisht AA, Wohlschlegel JA, Jacobsen SE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7474-9. doi: 10.1073/pnas.1406611111. Epub 2014 May 5.

19.

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.

Huang Y, Chavez L, Chang X, Wang X, Pastor WA, Kang J, Zepeda-Martínez JA, Pape UJ, Jacobsen SE, Peters B, Rao A.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1361-6. doi: 10.1073/pnas.1322921111. Epub 2014 Jan 13.

20.

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription.

Pastor WA, Aravind L, Rao A.

Nat Rev Mol Cell Biol. 2013 Jun;14(6):341-56. doi: 10.1038/nrm3589. Review.

21.

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

Ko M, An J, Bandukwala HS, Chavez L, Aijö T, Pastor WA, Segal MF, Li H, Koh KP, Lähdesmäki H, Hogan PG, Aravind L, Rao A.

Nature. 2013 May 2;497(7447):122-6. doi: 10.1038/nature12052. Epub 2013 Apr 7.

22.

The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine.

Pastor WA, Huang Y, Henderson HR, Agarwal S, Rao A.

Nat Protoc. 2012 Oct;7(10):1909-17. doi: 10.1038/nprot.2012.104. Epub 2012 Sep 27.

23.

The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine.

Huang Y, Pastor WA, Zepeda-Martínez JA, Rao A.

Nat Protoc. 2012 Oct;7(10):1897-908. doi: 10.1038/nprot.2012.103. Epub 2012 Sep 27.

24.

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.

Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, Ko M, McLoughlin EM, Brudno Y, Mahapatra S, Kapranov P, Tahiliani M, Daley GQ, Liu XS, Ecker JR, Milos PM, Agarwal S, Rao A.

Nature. 2011 May 19;473(7347):394-7. doi: 10.1038/nature10102. Epub 2011 May 8.

25.

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing.

Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A.

PLoS One. 2010 Jan 26;5(1):e8888. doi: 10.1371/journal.pone.0008888.

26.

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.

Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A.

Science. 2009 May 15;324(5929):930-5. doi: 10.1126/science.1170116. Epub 2009 Apr 16.

27.

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing.

Ansel KM, Pastor WA, Rath N, Lapan AD, Glasmacher E, Wolf C, Smith LC, Papadopoulou N, Lamperti ED, Tahiliani M, Ellwart JW, Shi Y, Kremmer E, Rao A, Heissmeyer V.

Nat Struct Mol Biol. 2008 May;15(5):523-30. doi: 10.1038/nsmb.1417. Epub 2008 Apr 27.

28.

Plasmid DNA vaccine-elicited cellular immune responses limit in vivo vaccine antigen expression through Fas-mediated apoptosis.

Greenland JR, Geiben R, Ghosh S, Pastor WA, Letvin NL.

J Immunol. 2007 May 1;178(9):5652-8.

29.

AIDS patient care: a social responsibility.

Pastor WA.

Health Prog. 1988 Mar;69(2):28, 30, 32. No abstract available.

PMID:
10286243

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