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Items: 1 to 50 of 84

1.

Hepatocyte Concentrations of Imaging Compounds Associated with Transporter Inhibition: Evidence in Perfused Rat Livers.

Bonnaventure P, Cusin F, Pastor CM.

Drug Metab Dispos. 2019 Apr;47(4):412-418. doi: 10.1124/dmd.118.084624. Epub 2019 Jan 23.

PMID:
30674615
2.

Liver Imaging and Hepatobiliary Contrast Media.

Pastor CM, Langer O, Van Beers BE.

Contrast Media Mol Imaging. 2018 Sep 9;2018:2487405. doi: 10.1155/2018/2487405. eCollection 2018. No abstract available.

3.

Isolated Perfused Rat Livers to Quantify the Pharmacokinetics and Concentrations of Gd-BOPTA.

Pastor CM.

Contrast Media Mol Imaging. 2018 Jul 11;2018:3839108. doi: 10.1155/2018/3839108. eCollection 2018.

4.

Quantification of hepatic perfusion and hepatocyte function with dynamic gadoxetic acid-enhanced MRI in patients with chronic liver disease.

Leporq B, Daire JL, Pastor CM, Deltenre P, Sempoux C, Schmidt S, Van Beers BE.

Clin Sci (Lond). 2018 Apr 16;132(7):813-824. doi: 10.1042/CS20171131. Print 2018 Apr 16.

PMID:
29440620
5.

Hepatocyte Concentrations of Indocyanine Green Reflect Transfer Rates Across Membrane Transporters.

Cusin F, Fernandes Azevedo L, Bonnaventure P, Desmeules J, Daali Y, Pastor CM.

Basic Clin Pharmacol Toxicol. 2017 Feb;120(2):171-178. doi: 10.1111/bcpt.12671. Epub 2016 Nov 3.

6.

Liver Perfusion Modifies Gd-DTPA and Gd-BOPTA Hepatocyte Concentrations Through Transfer Clearances Across Sinusoidal Membranes.

Daire JL, Leporq B, Vilgrain V, Van Beers BE, Schmidt S, Pastor CM.

Eur J Drug Metab Pharmacokinet. 2017 Aug;42(4):657-667. doi: 10.1007/s13318-016-0382-x.

PMID:
27778300
7.

Gadoxetate-enhanced MR imaging and compartmental modelling to assess hepatocyte bidirectional transport function in rats with advanced liver fibrosis.

Giraudeau C, Leporq B, Doblas S, Lagadec M, Pastor CM, Daire JL, Van Beers BE.

Eur Radiol. 2017 May;27(5):1804-1811. doi: 10.1007/s00330-016-4536-7. Epub 2016 Aug 23.

PMID:
27553933
8.

How transfer rates generate Gd-BOPTA concentrations in rat liver compartments: implications for clinical liver imaging with hepatobiliary contrast agents.

Pastor CM.

Contrast Media Mol Imaging. 2016 Jul;11(4):291-8. doi: 10.1002/cmmi.1691. Epub 2016 Apr 5.

PMID:
27060676
9.

Insights into the diagnosis of hepatocellular carcinomas with hepatobiliary MRI.

Vilgrain V, Van Beers BE, Pastor CM.

J Hepatol. 2016 Mar;64(3):708-16. doi: 10.1016/j.jhep.2015.11.016. Epub 2015 Nov 26. Review.

PMID:
26632635
10.

Quantification of drug transport function across the multiple resistance-associated protein 2 (Mrp2) in rat livers.

Bonnaventure P, Pastor CM.

Int J Mol Sci. 2014 Dec 24;16(1):135-47. doi: 10.3390/ijms16010135.

11.

Advanced fibrosis: Correlation between pharmacokinetic parameters at dynamic gadoxetate-enhanced MR imaging and hepatocyte organic anion transporter expression in rat liver.

Lagadec M, Doblas S, Giraudeau C, Ronot M, Lambert SA, Fasseu M, Paradis V, Moreau R, Pastor CM, Vilgrain V, Daire JL, Van Beers BE.

Radiology. 2015 Feb;274(2):379-86. doi: 10.1148/radiol.14140313. Epub 2014 Oct 7.

PMID:
25289480
12.

The role of organic anion transporters in diagnosing liver diseases by magnetic resonance imaging.

Pastor CM, Müllhaupt B, Stieger B.

Drug Metab Dispos. 2014 Apr;42(4):675-84. doi: 10.1124/dmd.113.055707. Epub 2014 Jan 7. Review.

PMID:
24398460
13.

Evidence of drug-drug interactions through uptake and efflux transport systems in rat hepatocytes: implications for cellular concentrations of competing drugs.

Daali Y, Millet P, Dayer P, Pastor CM.

Drug Metab Dispos. 2013 Aug;41(8):1548-56. doi: 10.1124/dmd.113.051870. Epub 2013 May 24.

PMID:
23708009
14.

Portal uptake function in veno-occlusive regions evaluated by real-time fluorescent imaging using indocyanine green.

Schmidt S, Denys A, Pastor CM.

J Hepatol. 2013 Sep;59(3):631-2. doi: 10.1016/j.jhep.2013.04.026. Epub 2013 May 9. No abstract available.

15.

Time-course proteomic analysis of taurocholate-induced necrotizing acute pancreatitis.

Fétaud-Lapierre V, Pastor CM, Jorge-Costa M, Hochstrasser DF, Morel DR, Frossard JL, Lescuyer P.

J Proteomics. 2013 Jun 24;85:12-27. doi: 10.1016/j.jprot.2013.04.022. Epub 2013 Apr 24.

PMID:
23624238
16.

Concentrations of Gd-BOPTA in cholestatic fatty rat livers: role of transport functions through membrane proteins.

Pastor CM, Wissmeyer M, Millet P.

Contrast Media Mol Imaging. 2013 Mar-Apr;8(2):147-56. doi: 10.1002/cmmi.1511.

PMID:
23281287
17.

Hepatic parenchymal enhancement at Gd-EOB-DTPA-enhanced MR imaging: correlation with morphological grading of severity in cirrhosis chronic hepatitis.

Pastor CM.

Magn Reson Imaging. 2012 Dec;30(10):1541-2. doi: 10.1016/j.mri.2012.04.006. Epub 2012 Jul 6. No abstract available.

PMID:
22770685
18.

Primovist, Eovist: what to expect?

Van Beers BE, Pastor CM, Hussain HK.

J Hepatol. 2012 Aug;57(2):421-9. doi: 10.1016/j.jhep.2012.01.031. Epub 2012 Apr 12. Review.

19.

Delayed production of IL-18 in lungs and pancreas of rats with acute pancreatitis.

Pastor CM, Morel DR, Vonlaufen A, Schiffer E, Lescuyer P, Frossard JL.

Pancreatology. 2010;10(6):752-7. doi: 10.1159/000317283. Epub 2011 Jan 26.

20.

How organic anions accumulate in hepatocytes lacking Mrp2: evidence in rat liver.

Millet P, Moulin M, Stieger B, Daali Y, Pastor CM.

J Pharmacol Exp Ther. 2011 Mar;336(3):624-32. doi: 10.1124/jpet.110.175406. Epub 2010 Dec 2.

PMID:
21131269
21.

Gadoxetic acid-enhanced hepatobiliary phase MR imaging: cellular insight.

Pastor CM.

Radiology. 2010 Nov;257(2):589. doi: 10.1148/radiol.101172. No abstract available.

PMID:
20959554
22.

Proteomic analysis of heat shock-induced protection in acute pancreatitis.

Fetaud-Lapierre V, Pastor CM, Farina A, Hochstrasser DF, Frossard JL, Lescuyer P.

J Proteome Res. 2010 Nov 5;9(11):5929-42. doi: 10.1021/pr100695d. Epub 2010 Sep 23.

PMID:
20815342
23.

Analysis of the pancreatic low molecular weight proteome in an animal model of acute pancreatitis.

Lassout O, Pastor CM, Fétaud-Lapierre V, Hochstrasser DF, Frossard JL, Lescuyer P.

J Proteome Res. 2010 Sep 3;9(9):4535-44. doi: 10.1021/pr1002627.

PMID:
20604530
24.

Experimental evidence of obesity as a risk factor for severe acute pancreatitis.

Frossard JL, Lescuyer P, Pastor CM.

World J Gastroenterol. 2009 Nov 14;15(42):5260-5.

25.

[Hepatopulmonary syndrome].

Thevenot T, Pastor CM, Cervoni JP, Jacquelinet C, Nguyen-Khac E, Richou C, Heyd B, Vanlemmens C, Mantion G, Di Martino V, Cadranel J.

Gastroenterol Clin Biol. 2009 Jun-Jul;33(6-7):565-79. doi: 10.1016/j.gcb.2009.03.013. Epub 2009 May 28. Review. French.

26.

Hepatic regeneration is decreased in a rat model of sinusoidal obstruction syndrome.

Schiffer E, Frossard JL, Rubbia-Brandt L, Mentha G, Pastor CM.

J Surg Oncol. 2009 Jun 1;99(7):439-46. doi: 10.1002/jso.21276.

PMID:
19353590
27.

Proteomic profiling in an animal model of acute pancreatitis.

Fétaud V, Frossard JL, Farina A, Pastor CM, Bühler L, Dumonceau JM, Hadengue A, Hochstrasser DF, Lescuyer P.

Proteomics. 2008 Sep;8(17):3621-31. doi: 10.1002/pmic.200800066.

PMID:
18686302
28.

Laparoscopic colon surgery: unreliability of end-tidal CO2 monitoring.

Klopfenstein CE, Schiffer E, Pastor CM, Beaussier M, Francis K, Soravia C, Herrmann FR.

Acta Anaesthesiol Scand. 2008 May;52(5):700-7. doi: 10.1111/j.1399-6576.2007.01568.x.

PMID:
18419725
29.

Acute pancreatitis.

Frossard JL, Steer ML, Pastor CM.

Lancet. 2008 Jan 12;371(9607):143-52. doi: 10.1016/S0140-6736(08)60107-5. Review.

PMID:
18191686
30.

Therapy Insight: hepatopulmonary syndrome and orthotopic liver transplantation.

Pastor CM, Schiffer E.

Nat Clin Pract Gastroenterol Hepatol. 2007 Nov;4(11):614-21. Review.

PMID:
17978818
31.

Opposite regulation of endothelial NO synthase by HSP90 and caveolin in liver and lungs of rats with hepatopulmonary syndrome.

Frossard JL, Schiffer E, Cikirikcioglu B, Bourquin J, Morel DR, Pastor CM.

Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G864-70.

32.

Improved visualization of vessels and hepatic tumors by micro-computed tomography (CT) using iodinated liposomes.

Montet X, Pastor CM, Vallée JP, Becker CD, Geissbuhler A, Morel DR, Meda P.

Invest Radiol. 2007 Sep;42(9):652-8.

PMID:
17700281
33.

Model-based analysis of Gd-BOPTA-induced MR signal intensity changes in cirrhotic rat livers.

Planchamp C, Gex-Fabry M, Becker CD, Pastor CM.

Invest Radiol. 2007 Jul;42(7):513-21.

PMID:
17568274
34.

Function of both sinusoidal and canalicular transporters controls the concentration of organic anions within hepatocytes.

Planchamp C, Hadengue A, Stieger B, Bourquin J, Vonlaufen A, Frossard JL, Quadri R, Becker CD, Pastor CM.

Mol Pharmacol. 2007 Apr;71(4):1089-97. Epub 2007 Jan 18.

PMID:
17234897
35.

Time course of lung injury in rat acute pancreatitis.

Morel DR, Frossard JL, Cikirikcioglu B, Tapponnier M, Pastor CM.

Intensive Care Med. 2006 Nov;32(11):1872-80. Epub 2006 Jul 15.

PMID:
16845510
36.

The role of junctional adhesion molecule C (JAM-C) in acute pancreatitis.

Vonlaufen A, Aurrand-Lions M, Pastor CM, Lamagna C, Hadengue A, Imhof BA, Frossard JL.

J Pathol. 2006 Aug;209(4):540-8.

PMID:
16767690
37.

Hepatopulmonary syndrome increases the postoperative mortality rate following liver transplantation: a prospective study in 90 patients.

Schiffer E, Majno P, Mentha G, Giostra E, Burri H, Klopfenstein CE, Beaussier M, Morel P, Hadengue A, Pastor CM.

Am J Transplant. 2006 Jun;6(6):1430-7.

38.

Neutrophil depletion--but not prevention of Kupffer cell activation--decreases the severity of cerulein-induced acute pancreatitis.

Pastor CM, Vonlaufen A, Georgi F, Hadengue A, Morel P, Frossard JL.

World J Gastroenterol. 2006 Feb 28;12(8):1219-24.

39.

Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis.

Demirag A, Pastor CM, Morel P, Jean-Christophe C, Sielenkämper AW, Güvener N, Mai G, Berney T, Frossard JL, Bühler LH.

World J Gastroenterol. 2006 Feb 14;12(6):915-20.

40.

Endothelial nitric oxide synthase regulation is altered in pancreas from cirrhotic rats.

Frossard JL, Quadri R, Hadengue A, Morel P, Pastor CM.

World J Gastroenterol. 2006 Jan 14;12(2):228-33.

41.

Quantification of Gd-BOPTA uptake and biliary excretion from dynamic magnetic resonance imaging in rat livers: model validation with 153Gd-BOPTA.

Planchamp C, Pastor CM, Balant L, Becker CD, Terrier F, Gex-Fabry M.

Invest Radiol. 2005 Nov;40(11):705-14.

PMID:
16230903
42.

Tracking mesenchymal stem cells in the liver by magnetic resonance imaging.

Pastor CM.

J Hepatol. 2005 Nov;43(5):915-6. Epub 2005 Aug 2. No abstract available.

PMID:
16171892
43.

Hsp70 does not mediate the hyperthermia-associated hyporesponsiveness to angiotensin in isolated rat portal veins.

Frossard JL, Mastrangelo D, Hadengue A, Pastor CM.

Life Sci. 2005 Nov 19;78(1):41-6. Epub 2005 Aug 18.

PMID:
16102782
44.

Cryotherapy treatment for cervical intraepithelial neoplasia: women's experiences in Peru.

Coffey PS, Bingham A, Winkler JL, Bishop A, Sellors JW, Lagos G, Pastor CM.

J Midwifery Womens Health. 2005 Jul-Aug;50(4):335-40.

PMID:
15973272
45.

Direct evidence of the temperature dependence of Gd-BOPTA transport in the intact rat liver.

Planchamp C, Beyer GJ, Slosman DO, Terrier F, Pastor CM.

Appl Radiat Isot. 2005 Jun;62(6):943-9. Epub 2005 Jan 7.

PMID:
15799874
46.

Magnetic resonance imaging with hepatospecific contrast agents in cirrhotic rat livers.

Planchamp C, Montet X, Frossard JL, Quadri R, Stieger B, Meier PJ, Ivancevic MK, Vallée JP, Terrier F, Pastor CM.

Invest Radiol. 2005 Apr;40(4):187-94.

PMID:
15770136
47.

Role of Toll-like receptor 4 on pancreatic and pulmonary injury in a mice model of acute pancreatitis associated with endotoxemia.

Pastor CM, Pugin J, Kwak B, Chanson M, Mach F, Hadengue A, Frossard JL.

Crit Care Med. 2004 Aug;32(8):1759-63.

PMID:
15286555
48.

Gd-BOPTA transport into rat hepatocytes: pharmacokinetic analysis of dynamic magnetic resonance images using a hollow-fiber bioreactor.

Planchamp C, Gex-Fabry M, Dornier C, Quadri R, Reist M, Ivancevic MK, Vallée JP, Pochon S, Terrier F, Balant L, Stieger B, Meier PJ, Pastor CM.

Invest Radiol. 2004 Aug;39(8):506-15.

PMID:
15257212
49.

Hyperthermia decreases the response to vasoconstrictors in rat portal veins.

Pastor CM.

Eur J Pharmacol. 2004 Jun 28;494(2-3):191-7.

PMID:
15212974
50.

Hollow fiber bioreactor: new development for the study of contrast agent transport into hepatocytes by magnetic resonance imaging.

Planchamp C, Ivancevic MK, Pastor CM, Vallée JP, Pochon S, Terrier F, Mayer JM, Reist M.

Biotechnol Bioeng. 2004 Mar 20;85(6):656-65.

PMID:
14966807

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