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Items: 1 to 50 of 58

1.

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

Caron P, Pankotai T, Wiegant WW, Tollenaere MAX, Furst A, Bonhomme C, Helfricht A, de Groot A, Pastink A, Vertegaal ACO, Luijsterburg MS, Soutoglou E, van Attikum H.

Genes Dev. 2019 Jun 1;33(11-12):684-704. doi: 10.1101/gad.321943.118. Epub 2019 May 2.

2.

Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling.

Smeenk G, Wiegant WW, Marteijn JA, Luijsterburg MS, Sroczynski N, Costelloe T, Romeijn RJ, Pastink A, Mailand N, Vermeulen W, van Attikum H.

J Cell Sci. 2013 Feb 15;126(Pt 4):889-903. doi: 10.1242/jcs.109413. Epub 2012 Dec 21.

3.

Meiosis in mice without a synaptonemal complex.

Kouznetsova A, Benavente R, Pastink A, Höög C.

PLoS One. 2011;6(12):e28255. doi: 10.1371/journal.pone.0028255. Epub 2011 Dec 2.

4.

Artemis splice defects cause atypical SCID and can be restored in vitro by an antisense oligonucleotide.

Ijspeert H, Lankester AC, van den Berg JM, Wiegant W, van Zelm MC, Weemaes CM, Warris A, Pan-Hammarström Q, Pastink A, van Tol MJ, van Dongen JJ, van Gent DC, van der Burg M.

Genes Immun. 2011 Sep;12(6):434-44. doi: 10.1038/gene.2011.16. Epub 2011 Mar 10.

PMID:
21390052
5.

The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage.

Smeenk G, Wiegant WW, Vrolijk H, Solari AP, Pastink A, van Attikum H.

J Cell Biol. 2010 Sep 6;190(5):741-9. doi: 10.1083/jcb.201001048. Epub 2010 Aug 30.

6.

Rad51C is essential for embryonic development and haploinsufficiency causes increased DNA damage sensitivity and genomic instability.

Smeenk G, de Groot AJ, Romeijn RJ, van Buul PP, Zdzienicka MZ, Mullenders LH, Pastink A, Godthelp BC.

Mutat Res. 2010 Jul 7;689(1-2):50-8. doi: 10.1016/j.mrfmmm.2010.05.001. Epub 2010 May 13.

PMID:
20471405
7.

A novel radiosensitive SCID patient with a pronounced G(2)/M sensitivity.

Wiegant WW, Meyers M, Verkaik NS, van der Burg M, Darroudi F, Romeijn R, Bernatowska E, Wolska-Kusnierz B, Mikoluc B, Jaspers NG, Vreeken C, Ijspeert H, Esveldt-van Lange RE, Friedl AA, de Villartay JP, Mullenders LH, van Dongen JJ, van Gent DC, Pastink A, Zdzienicka MZ.

DNA Repair (Amst). 2010 Apr 4;9(4):365-73. doi: 10.1016/j.dnarep.2009.12.004. Epub 2010 Jan 15.

PMID:
20079696
8.

Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair.

Vrouwe MG, Elghalbzouri-Maghrani E, Meijers M, Schouten P, Godthelp BC, Bhuiyan ZA, Redeker EJ, Mannens MM, Mullenders LH, Pastink A, Darroudi F.

Hum Mol Genet. 2007 Jun 15;16(12):1478-87. Epub 2007 Apr 27.

PMID:
17468178
9.

Schizosaccharomyces pombe Rad22A and Rad22B have similar biochemical properties and form multimeric structures.

de Vries FA, Zonneveld JB, de Groot AJ, Koning RI, van Zeeland AA, Pastink A.

Mutat Res. 2007 Feb 3;615(1-2):143-52. Epub 2006 Dec 16.

PMID:
17208257
10.

Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi.

van Haaften G, Romeijn R, Pothof J, Koole W, Mullenders LH, Pastink A, Plasterk RH, Tijsterman M.

Curr Biol. 2006 Jul 11;16(13):1344-50.

11.

Two levels of interference in mouse meiotic recombination.

de Boer E, Stam P, Dietrich AJ, Pastink A, Heyting C.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9607-12. Epub 2006 Jun 9.

12.

Inactivation of RAD52 aggravates RAD54 defects in mice but not in Schizosaccharomyces pombe.

de Vries FA, Zonneveld JB, van Duijn-Goedhart A, Roodbergen M, Boei J, van Buul PP, Essers J, van Steeg H, van Zeeland AA, van Benthem J, Pastink A.

DNA Repair (Amst). 2005 Sep 28;4(10):1121-8.

PMID:
16009599
13.

Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation.

de Vries FA, de Boer E, van den Bosch M, Baarends WM, Ooms M, Yuan L, Liu JG, van Zeeland AA, Heyting C, Pastink A.

Genes Dev. 2005 Jun 1;19(11):1376-89.

14.

Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52.

van Veelen LR, Essers J, van de Rakt MW, Odijk H, Pastink A, Zdzienicka MZ, Paulusma CC, Kanaar R.

Mutat Res. 2005 Jul 1;574(1-2):34-49. Epub 2005 Apr 9.

PMID:
15914205
15.

Lig4 and rad54 are required for repair of DNA double-strand breaks induced by P-element excision in Drosophila.

Romeijn RJ, Gorski MM, van Schie MA, Noordermeer JN, Mullenders LH, Ferro W, Pastink A.

Genetics. 2005 Feb;169(2):795-806. Epub 2004 Nov 15.

16.

Genetic steps of mammalian homologous repair with distinct mutagenic consequences.

Stark JM, Pierce AJ, Oh J, Pastink A, Jasin M.

Mol Cell Biol. 2004 Nov;24(21):9305-16.

17.

Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae.

Gorski MM, Romeijn RJ, Eeken JC, de Jong AW, van Veen BL, Szuhai K, Mullenders LH, Ferro W, Pastink A.

DNA Repair (Amst). 2004 Jun 3;3(6):603-15.

PMID:
15135728
18.

The Drosophila melanogaster DNA Ligase IV gene plays a crucial role in the repair of radiation-induced DNA double-strand breaks and acts synergistically with Rad54.

Gorski MM, Eeken JC, de Jong AW, Klink I, Loos M, Romeijn RJ, van Veen BL, Mullenders LH, Ferro W, Pastink A.

Genetics. 2003 Dec;165(4):1929-41.

19.

CTG repeat instability and size variation timing in DNA repair-deficient mice.

Savouret C, Brisson E, Essers J, Kanaar R, Pastink A, te Riele H, Junien C, Gourdon G.

EMBO J. 2003 May 1;22(9):2264-73.

20.

Induction of epithelial tumors in Drosophila melanogaster heterozygous for the tumor suppressor gene wts.

Eeken JC, Klink I, van Veen BL, Pastink A, Ferro W.

Environ Mol Mutagen. 2002;40(4):277-82.

PMID:
12489118
21.

DNA double-strand break repair by homologous recombination.

van den Bosch M, Lohman PH, Pastink A.

Biol Chem. 2002 Jun;383(6):873-92. Review.

PMID:
12222678
22.

Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage.

Essers J, Houtsmuller AB, van Veelen L, Paulusma C, Nigg AL, Pastink A, Vermeulen W, Hoeijmakers JH, Kanaar R.

EMBO J. 2002 Apr 15;21(8):2030-7.

23.

Differential expression and requirements for Schizosaccharomyces pombe RAD52 homologs in DNA repair and recombination.

van den Bosch M, Zonneveld JB, Vreeken K, de Vries FA, Lohman PH, Pastink A.

Nucleic Acids Res. 2002 Mar 15;30(6):1316-24.

24.

Isolation and characterization of the RAD59 homologue of Kluyveromyces lactis.

van den Bosch M, Zonneveld JB, Lohman PH, Pastink A.

Curr Genet. 2001 Jul;39(5-6):305-10.

PMID:
11525403
25.

Genomic integrity and the repair of double-strand DNA breaks.

Pastink A, Eeken JC, Lohman PH.

Mutat Res. 2001 Sep 1;480-481:37-50. Review.

PMID:
11506797
26.

Isolation and genetic characterisation of the Drosophila homologue of (SCE)REV3, encoding the catalytic subunit of DNA polymerase zeta.

Eeken JC, Romeijn RJ, de Jong AW, Pastink A, Lohman PH.

Mutat Res. 2001 Apr 4;485(3):237-53.

PMID:
11267835
27.

Characterization of RAD52 homologs in the fission yeast Schizosaccharomyces pombe.

van den Bosch M, Vreeken K, Zonneveld JB, Brandsma JA, Lombaerts M, Murray JM, Lohman PH, Pastink A.

Mutat Res. 2001 Jan 5;461(4):311-23.

PMID:
11104907
28.
30.

Repair and consequences of double-strand breaks in DNA.

Pastink A, Lohman PH.

Mutat Res. 1999 Jul 16;428(1-2):141-56. Review. No abstract available.

PMID:
10517988
32.

Identification and characterisation of the Drosophila melanogaster O6-alkylguanine-DNA alkyltransferase cDNA.

Kooistra R, Zonneveld JB, Watson AJ, Margison GP, Lohman PH, Pastink A.

Nucleic Acids Res. 1999 Apr 15;27(8):1795-801.

33.

Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation.

Rijkers T, Van Den Ouweland J, Morolli B, Rolink AG, Baarends WM, Van Sloun PP, Lohman PH, Pastink A.

Mol Cell Biol. 1998 Nov;18(11):6423-9.

34.

The Drosophila melanogaster RAD54 homolog, DmRAD54, is involved in the repair of radiation damage and recombination.

Kooistra R, Vreeken K, Zonneveld JB, de Jong A, Eeken JC, Osgood CJ, Buerstedde JM, Lohman PH, Pastink A.

Mol Cell Biol. 1997 Oct;17(10):6097-104.

35.
36.

Homologous recombination in the fission yeast Schizosaccharomyces pombe: different requirements for the rhp51+, rhp54+ and rad22+ genes.

Muris DF, Vreeken K, Schmidt H, Ostermann K, Clever B, Lohman PH, Pastink A.

Curr Genet. 1997 Mar;31(3):248-54.

PMID:
9065388
37.

Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation.

Kanaar R, Troelstra C, Swagemakers SM, Essers J, Smit B, Franssen JH, Pastink A, Bezzubova OY, Buerstedde JM, Clever B, Heyer WD, Hoeijmakers JH.

Curr Biol. 1996 Jul 1;6(7):828-38.

39.

Isolation of the Schizosaccharomyces pombe RAD54 homologue, rhp54+, a gene involved in the repair of radiation damage and replication fidelity.

Muris DF, Vreeken K, Carr AM, Murray JM, Smit C, Lohman PH, Pastink A.

J Cell Sci. 1996 Jan;109 ( Pt 1):73-81.

40.

The nature of X-ray-induced mutations in mature sperm and spermatogonial cells of Drosophila melanogaster.

Eeken JC, de Jong AW, Loos M, Vreeken C, Romeyn R, Pastink A, Lohman PH.

Mutat Res. 1994 May 1;307(1):201-12.

PMID:
7513798
41.

Cloning the RAD51 homologue of Schizosaccharomyces pombe.

Muris DF, Vreeken K, Carr AM, Broughton BC, Lehmann AR, Lohman PH, Pastink A.

Nucleic Acids Res. 1993 Sep 25;21(19):4586-91.

42.
43.

DNA base sequence changes induced by diethyl sulfate in postmeiotic male germ cells of Drosophila melanogaster.

Sierra LM, Pastink A, Nivard MJ, Vogel EW.

Mol Gen Genet. 1993 Mar;237(3):370-4.

PMID:
8483451
44.

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

Koken MH, Vreeken C, Bol SA, Cheng NC, Jaspers-Dekker I, Hoeijmakers JH, Eeken JC, Weeda G, Pastink A.

Nucleic Acids Res. 1992 Nov 11;20(21):5541-8.

45.
46.

Characterization of MR (P) strains of Drosophila melanogaster: the number of intact P elements and their genetic effect.

Eeken JC, Romeyn RJ, de Jong AW, Yannopoulos G, Pastink A.

Genet Res. 1991 Dec;58(3):211-23.

PMID:
1666390
47.

Mutational specificity of ethyl methanesulfonate in excision-repair-proficient and -deficient strains of Drosophila melanogaster.

Pastink A, Heemskerk E, Nivard MJ, van Vliet CJ, Vogel EW.

Mol Gen Genet. 1991 Oct;229(2):213-8.

PMID:
1921971
48.

The nature of X-ray-induced mutations after recovery in excision repair-deficient (mus-201) Drosophila females.

Eeken JC, Vreeken C, de Jong AW, Pastink A.

Mutat Res. 1991 Mar;247(1):129-40.

PMID:
1900568
49.

Transformation and immortalization of diploid xeroderma pigmentosum fibroblasts.

Klein B, Pastink A, Odijk H, Westerveld A, van der Eb AJ.

Exp Cell Res. 1990 Dec;191(2):256-62.

PMID:
2175267
50.

Mutations induced at the white and vermilion loci in Drosophila melanogaster.

Pastink A, Vreeken C, Vogel EW, Eeken JC.

Mutat Res. 1990 Jul;231(1):63-71.

PMID:
2114534

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