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Items: 29

1.

Generation of a Jurkat-based fluorescent reporter cell line to evaluate lipid antigen interaction with the human iNKT cell receptor.

Humeniuk P, Geiselhart S, Battin C, Webb T, Steinberger P, Paster W, Hoffmann-Sommergrsuber K.

Sci Rep. 2019 May 15;9(1):7426. doi: 10.1038/s41598-019-43529-4.

2.

A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies.

Rosskopf S, Leitner J, Paster W, Morton LT, Hagedoorn RS, Steinberger P, Heemskerk MHM.

Oncotarget. 2018 Apr 3;9(25):17608-17619. doi: 10.18632/oncotarget.24807. eCollection 2018 Apr 3.

3.

A cellular platform for the evaluation of immune checkpoint molecules.

Jutz S, Hennig A, Paster W, Asrak Ö, Dijanovic D, Kellner F, Pickl WF, Huppa JB, Leitner J, Steinberger P.

Oncotarget. 2017 May 4;8(39):64892-64906. doi: 10.18632/oncotarget.17615. eCollection 2017 Sep 12.

4.

A human monocytic NF-κB fluorescent reporter cell line for detection of microbial contaminants in biological samples.

Battin C, Hennig A, Mayrhofer P, Kunert R, Zlabinger GJ, Steinberger P, Paster W.

PLoS One. 2017 May 24;12(5):e0178220. doi: 10.1371/journal.pone.0178220. eCollection 2017.

5.

Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-κB, NFAT and AP-1.

Jutz S, Leitner J, Schmetterer K, Doel-Perez I, Majdic O, Grabmeier-Pfistershammer K, Paster W, Huppa JB, Steinberger P.

J Immunol Methods. 2016 Mar;430:10-20. doi: 10.1016/j.jim.2016.01.007. Epub 2016 Jan 15.

6.

Association of CD147 and Calcium Exporter PMCA4 Uncouples IL-2 Expression from Early TCR Signaling.

Supper V, Schiller HB, Paster W, Forster F, Boulègue C, Mitulovic G, Leksa V, Ohradanova-Repic A, Machacek C, Schatzlmaier P, Zlabinger GJ, Stockinger H.

J Immunol. 2016 Feb 1;196(3):1387-99. doi: 10.4049/jimmunol.1501889. Epub 2016 Jan 4.

7.

A THEMIS:SHP1 complex promotes T-cell survival.

Paster W, Bruger AM, Katsch K, Grégoire C, Roncagalli R, Fu G, Gascoigne NR, Nika K, Cohnen A, Feller SM, Simister PC, Molder KC, Cordoba SP, Dushek O, Malissen B, Acuto O.

EMBO J. 2015 Feb 3;34(3):393-409. doi: 10.15252/embj.201387725. Epub 2014 Dec 22.

8.

The late endosomal transporter CD222 directs the spatial distribution and activity of Lck.

Pfisterer K, Forster F, Paster W, Supper V, Ohradanova-Repic A, Eckerstorfer P, Zwirzitz A, Donner C, Boulegue C, Schiller HB, Ondrovičová G, Acuto O, Stockinger H, Leksa V.

J Immunol. 2014 Sep 15;193(6):2718-32. doi: 10.4049/jimmunol.1303349. Epub 2014 Aug 15.

9.

Fine-tuning T cell receptor signaling to control T cell development.

Fu G, Rybakin V, Brzostek J, Paster W, Acuto O, Gascoigne NR.

Trends Immunol. 2014 Jul;35(7):311-8. doi: 10.1016/j.it.2014.05.003. Epub 2014 Jun 17. Review.

10.

The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness.

Rainero E, Cianflone C, Porporato PE, Chianale F, Malacarne V, Bettio V, Ruffo E, Ferrara M, Benecchia F, Capello D, Paster W, Locatelli I, Bertoni A, Filigheddu N, Sinigaglia F, Norman JC, Baldanzi G, Graziani A.

PLoS One. 2014 Jun 2;9(6):e97144. doi: 10.1371/journal.pone.0097144. eCollection 2014.

11.

Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton.

Forster F, Paster W, Supper V, Schatzlmaier P, Sunzenauer S, Ostler N, Saliba A, Eckerstorfer P, Britzen-Laurent N, Schütz G, Schmid JA, Zlabinger GJ, Naschberger E, Stürzl M, Stockinger H.

J Immunol. 2014 Jan 15;192(2):771-81. doi: 10.4049/jimmunol.1300377. Epub 2013 Dec 13.

12.

Themis sets the signal threshold for positive and negative selection in T-cell development.

Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, Brzostek J, Hoerter JA, Paster W, Acuto O, Cheroutre H, Sauer K, Gascoigne NR.

Nature. 2013 Dec 19;504(7480):441-5. doi: 10.1038/nature12718. Epub 2013 Nov 13.

13.

GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development.

Paster W, Brockmeyer C, Fu G, Simister PC, de Wet B, Martinez-Riaño A, Hoerter JA, Feller SM, Wülfing C, Gascoigne NR, Acuto O.

J Immunol. 2013 Apr 1;190(7):3749-56. doi: 10.4049/jimmunol.1203389. Epub 2013 Mar 4.

14.

T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.

Stirnweiss A, Hartig R, Gieseler S, Lindquist JA, Reichardt P, Philipsen L, Simeoni L, Poltorak M, Merten C, Zuschratter W, Prokazov Y, Paster W, Stockinger H, Harder T, Gunzer M, Schraven B.

Sci Signal. 2013 Feb 19;6(263):ra13. doi: 10.1126/scisignal.2003607.

PMID:
23423439
15.

T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component.

Brockmeyer C, Paster W, Pepper D, Tan CP, Trudgian DC, McGowan S, Fu G, Gascoigne NR, Acuto O, Salek M.

J Biol Chem. 2011 Mar 4;286(9):7535-47. doi: 10.1074/jbc.M110.201236. Epub 2010 Dec 28.

16.

Detection of protein-protein interactions in the live cell plasma membrane by quantifying prey redistribution upon bait micropatterning.

Weghuber J, Brameshuber M, Sunzenauer S, Lehner M, Paar C, Haselgrübler T, Schwarzenbacher M, Kaltenbrunner M, Hesch C, Paster W, Heise B, Sonnleitner A, Stockinger H, Schütz GJ.

Methods Enzymol. 2010;472:133-51. doi: 10.1016/S0076-6879(10)72012-7.

PMID:
20580963
17.

Constitutively active Lck kinase in T cells drives antigen receptor signal transduction.

Nika K, Soldani C, Salek M, Paster W, Gray A, Etzensperger R, Fugger L, Polzella P, Cerundolo V, Dushek O, Höfer T, Viola A, Acuto O.

Immunity. 2010 Jun 25;32(6):766-77. doi: 10.1016/j.immuni.2010.05.011. Epub 2010 Jun 11.

18.

Proximal human FOXP3 promoter transactivated by NF-kappaB and negatively controlled by feedback loop and SP3.

Eckerstorfer P, Novy M, Burgstaller-Muehlbacher S, Paster W, Schiller HB, Mayer H, Stockinger H.

Mol Immunol. 2010 Jul;47(11-12):2094-102. doi: 10.1016/j.molimm.2010.04.002. Epub 2010 May 11.

19.

Direct observation and quantitative analysis of Lck exchange between plasma membrane and cytosol in living T cells.

Zimmermann L, Paster W, Weghuber J, Eckerstorfer P, Stockinger H, Schütz GJ.

J Biol Chem. 2010 Feb 26;285(9):6063-70. doi: 10.1074/jbc.M109.025981. Epub 2009 Dec 29.

20.

Sequential cooperation of CD2 and CD48 in the buildup of the early TCR signalosome.

Muhammad A, Schiller HB, Forster F, Eckerstorfer P, Geyeregger R, Leksa V, Zlabinger GJ, Sibilia M, Sonnleitner A, Paster W, Stockinger H.

J Immunol. 2009 Jun 15;182(12):7672-80. doi: 10.4049/jimmunol.0800691.

21.

Genetically encoded Förster resonance energy transfer sensors for the conformation of the Src family kinase Lck.

Paster W, Paar C, Eckerstorfer P, Jakober A, Drbal K, Schütz GJ, Sonnleitner A, Stockinger H.

J Immunol. 2009 Feb 15;182(4):2160-7. doi: 10.4049/jimmunol.0802639.

22.

Micropatterning for quantitative analysis of protein-protein interactions in living cells.

Schwarzenbacher M, Kaltenbrunner M, Brameshuber M, Hesch C, Paster W, Weghuber J, Heise B, Sonnleitner A, Stockinger H, Schütz GJ.

Nat Methods. 2008 Dec;5(12):1053-60. doi: 10.1038/nmeth.1268. Epub 2008 Nov 9.

PMID:
18997782
23.

Guanylate binding protein-1 inhibits spreading and migration of endothelial cells through induction of integrin alpha4 expression.

Weinländer K, Naschberger E, Lehmann MH, Tripal P, Paster W, Stockinger H, Hohenadl C, Stürzl M.

FASEB J. 2008 Dec;22(12):4168-78. doi: 10.1096/fj.08-107524. Epub 2008 Aug 12.

PMID:
18697840
24.

The cytoplasmic tail of CD45 is released from activated phagocytes and can act as an inhibitory messenger for T cells.

Kirchberger S, Majdic O, Blüml S, Schrauf C, Leitner J, Gerner C, Paster W, Gundacker N, Sibilia M, Stöckl J.

Blood. 2008 Aug 15;112(4):1240-8. doi: 10.1182/blood-2008-02-138131. Epub 2008 May 29.

25.

High throughput FRET screening of the plasma membrane based on TIRFM.

Paar C, Paster W, Stockinger H, Schütz GJ, Sonnleitner M, Sonnleitner A.

Cytometry A. 2008 May;73(5):442-50. doi: 10.1002/cyto.a.20551.

26.

LFA-1-mediated leukocyte adhesion regulated by interaction of CD43 with LFA-1 and CD147.

Khunkaewla P, Schiller HB, Paster W, Leksa V, Cermák L, Andera L, Horejsí V, Stockinger H.

Mol Immunol. 2008 Mar;45(6):1703-11. Epub 2007 Nov 9.

PMID:
17996943
27.

In vivo plasmid DNA electroporation generates exceptionally high levels of epitope-specific CD8+ T-cell responses.

Paster W, Zehetner M, Kalat M, Schüller S, Schweighoffer T.

Gene Ther. 2003 May;10(9):717-24.

PMID:
12704410
28.

In vivo plasmid electroporation induces tumor antigen-specific CD8+ T-cell responses and delays tumor growth in a syngeneic mouse melanoma model.

Kalat M, Küpcü Z, Schüller S, Zalusky D, Zehetner M, Paster W, Schweighoffer T.

Cancer Res. 2002 Oct 1;62(19):5489-94.

29.

Structural elements of a protein antigen determine immunogenicity of the embedded MHC class I-restricted T cell epitope.

Paster W, Kalat M, Zehetner M, Schweighoffer T.

J Immunol. 2002 Sep 15;169(6):2937-46.

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