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Items: 1 to 50 of 190

1.

Individual DNA Methylation Profile Is Correlated with Age and Can Be Targeted to Modulate Healthy Aging and Longevity.

Guarasci F, Aquila P, Montesanto A, Corsonello A, Bellizzi D, Passarino G.

Curr Pharm Des. 2019 Nov 11. doi: 10.2174/1381612825666191112095655. [Epub ahead of print]

PMID:
31721695
2.

Correction for: LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice.

Malavolta M, Dato S, Villa F, De Rango F, Iannone F, Ferrario A, Maciag A, Ciaglia E, D'amato A, Carrizzo A, Basso A, Orlando F, Provinciali M, Madeddu P, Passarino G, Vecchione C, Rose G, Puca AA.

Aging (Albany NY). 2019 Oct 25;11(20):9220. doi: 10.18632/aging.102398. Epub 2019 Oct 25. No abstract available.

3.

Mini Nutritional Assessment Scores Indicate Higher Risk for Prospective Mortality and Contrasting Correlation With Age-Related Epigenetic Biomarkers.

Montesanto A, D'Aquila P, Rossano V, Passarino G, Bellizzi D.

Front Endocrinol (Lausanne). 2019 Oct 1;10:672. doi: 10.3389/fendo.2019.00672. eCollection 2019.

4.

LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice.

Malavolta M, Dato S, Villa F, Rango F, Iannone F, Ferrario A, Maciag A, Ciaglia E, D'amato A, Carrizzo A, Basso A, Orlando F, Provinciali M, Madeddu P, Passarino G, Vecchione C, Rose G, Puca AA.

Aging (Albany NY). 2019 Aug 28;11(16):6555-6568. doi: 10.18632/aging.102209. Epub 2019 Aug 28. Erratum in: Aging (Albany NY). 2019 Oct 25;11(20):9220.

5.

Erythropoietin (EPO) haplotype associated with all-cause mortality in a cohort of Italian patients with Type-2 Diabetes.

Montesano A, Bonfigli AR, De Luca M, Crocco P, Garagnani P, Marasco E, Pirazzini C, Giuliani C, Romagnoli F, Franceschi C, Passarino G, Testa R, Olivieri F, Rose G.

Sci Rep. 2019 Jul 17;9(1):10395. doi: 10.1038/s41598-019-46894-2.

6.

Anti-tumor Activity and Epigenetic Impact of the Polyphenol Oleacein in Multiple Myeloma.

Juli G, Oliverio M, Bellizzi D, Gallo Cantafio ME, Grillone K, Passarino G, Colica C, Nardi M, Rossi M, Procopio A, Tagliaferri P, Tassone P, Amodio N.

Cancers (Basel). 2019 Jul 16;11(7). pii: E990. doi: 10.3390/cancers11070990.

7.

Inter-Individual Variability in Xenobiotic-Metabolizing Enzymes: Implications for Human Aging and Longevity.

Crocco P, Montesanto A, Dato S, Geracitano S, Iannone F, Passarino G, Rose G.

Genes (Basel). 2019 May 27;10(5). pii: E403. doi: 10.3390/genes10050403.

8.

Epigenetic signature: implications for mitochondrial quality control in human aging.

D'Aquila P, Montesanto A, De Rango F, Guarasci F, Passarino G, Bellizzi D.

Aging (Albany NY). 2019 Feb 20;11(4):1240-1251. doi: 10.18632/aging.101832.

9.

Inositol Polyphosphate Multikinase (IPMK), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity.

De Rango F, Crocco P, Iannone F, Saiardi A, Passarino G, Dato S, Rose G.

Genes (Basel). 2019 Feb 8;10(2). pii: E125. doi: 10.3390/genes10020125.

10.

Cardiovascular risk profiling of long-lived people shows peculiar associations with mortality compared with younger individuals.

Montesanto A, Pellegrino D, Geracitano S, La Russa D, Mari V, Garasto S, Lattanzio F, Corsonello A, Passarino G.

Geriatr Gerontol Int. 2019 Feb;19(2):165-170. doi: 10.1111/ggi.13578. Epub 2018 Dec 16.

PMID:
30556373
11.

Uncoupling protein 4 (UCP4) gene variability in neurodegenerative disorders: further evidence of association in Frontotemporal dementia.

Montesanto A, Crocco P, Dato S, Geracitano S, Frangipane F, Colao R, Maletta R, Passarino G, Bruni AC, Rose G.

Aging (Albany NY). 2018 Nov 13;10(11):3283-3293. doi: 10.18632/aging.101632.

12.

Amino acids and amino acid sensing: implication for aging and diseases.

Dato S, Hoxha E, Crocco P, Iannone F, Passarino G, Rose G.

Biogerontology. 2019 Feb;20(1):17-31. doi: 10.1007/s10522-018-9770-8. Epub 2018 Sep 25. Review.

PMID:
30255223
13.

Heterogeneity of Thyroid Function and Impact of Peripheral Thyroxine Deiodination in Centenarians and Semi-Supercentenarians: Association With Functional Status and Mortality.

Ostan R, Monti D, Mari D, Arosio B, Gentilini D, Ferri E, Passarino G, De Rango F, D'Aquila P, Mariotti S, Pasquali R, Fanelli F, Bucci L, Franceschi C, Vitale G.

J Gerontol A Biol Sci Med Sci. 2019 May 16;74(6):802-810. doi: 10.1093/gerona/gly194.

14.

Impact of demography and population dynamics on the genetic architecture of human longevity.

Giuliani C, Sazzini M, Pirazzini C, Bacalini MG, Marasco E, Ruscone GAG, Fang F, Sarno S, Gentilini D, Di Blasio AM, Crocco P, Passarino G, Mari D, Monti D, Nacmias B, Sorbi S, Salvarani C, Catanoso M, Pettener D, Luiselli D, Ukraintseva S, Yashin A, Franceschi C, Garagnani P.

Aging (Albany NY). 2018 Aug 8;10(8):1947-1963. doi: 10.18632/aging.101515.

15.

Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring.

Sizzano F, Collino S, Cominetti O, Monti D, Garagnani P, Ostan R, Pirazzini C, Bacalini MG, Mari D, Passarino G, Franceschi C, Palini A.

Mediators Inflamm. 2018 Feb 19;2018:7109312. doi: 10.1155/2018/7109312. eCollection 2018.

16.

Physical decline and survival in the elderly are affected by the genetic variability of amino acid transporter genes.

Crocco P, Hoxha E, Dato S, De Rango F, Montesanto A, Rose G, Passarino G.

Aging (Albany NY). 2018 Apr 18;10(4):658-673. doi: 10.18632/aging.101420.

17.

The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.

Dato S, Soerensen M, De Rango F, Rose G, Christensen K, Christiansen L, Passarino G.

Aging Cell. 2018 Jun;17(3):e12755. doi: 10.1111/acel.12755. Epub 2018 Mar 25.

18.

Aging and nutrition induce tissue-specific changes on global DNA methylation status in rats.

Guarasci F, D'Aquila P, Mandalà M, Garasto S, Lattanzio F, Corsonello A, Passarino G, Bellizzi D.

Mech Ageing Dev. 2018 Sep;174:47-54. doi: 10.1016/j.mad.2018.02.001. Epub 2018 Feb 7. Review.

PMID:
29427568
19.

Genes associated with Type 2 Diabetes and vascular complications.

Montesanto A, Bonfigli AR, Crocco P, Garagnani P, De Luca M, Boemi M, Marasco E, Pirazzini C, Giuliani C, Franceschi C, Passarino G, Testa R, Olivieri F, Rose G.

Aging (Albany NY). 2018 Feb 4;10(2):178-196. doi: 10.18632/aging.101375.

20.

Reconstructing the genetic history of Italians: new insights from a male (Y-chromosome) perspective.

Grugni V, Raveane A, Mattioli F, Battaglia V, Sala C, Toniolo D, Ferretti L, Gardella R, Achilli A, Olivieri A, Torroni A, Passarino G, Semino O.

Ann Hum Biol. 2018 Feb;45(1):44-56. doi: 10.1080/03014460.2017.1409801.

PMID:
29382284
21.

rRNA-gene methylation and biological aging.

D'Aquila P, Bellizzi D, Passarino G.

Aging (Albany NY). 2018 Jan 24;10(1):7-8. doi: 10.18632/aging.101369. No abstract available.

22.

Frequency of Cardiovascular Genetic Risk Factors in a Calabrian Population and Their Effects on Dementia.

Maletta R, Smirne N, Bernardi L, Anfossi M, Gallo M, Conidi ME, Colao R, Puccio G, Curcio SAM, Laganà V, Frangipane F, Cupidi C, Mirabelli M, Vasso F, Torchia G, Muraca MG, Di Lorenzo R, Rose G, Montesanto A, Passarino G, Bruni AC.

J Alzheimers Dis. 2018;61(3):1179-1187. doi: 10.3233/JAD-170687.

PMID:
29332048
23.

A Genetic Variant of ASCT2 Hampers In Vitro RNA Splicing and Correlates with Human Longevity.

D'Aquila P, Crocco P, De Rango F, Indiveri C, Bellizzi D, Rose G, Passarino G.

Rejuvenation Res. 2018 Jun;21(3):193-199. doi: 10.1089/rej.2017.1948. Epub 2017 Sep 8.

PMID:
28885889
24.

Centenarians as a 21st century healthy aging model: A legacy of humanity and the need for a world-wide consortium (WWC100+).

Franceschi C, Passarino G, Mari D, Monti D.

Mech Ageing Dev. 2017 Jul;165(Pt B):55-58. doi: 10.1016/j.mad.2017.06.002. Epub 2017 Jun 23. No abstract available.

PMID:
28651996
25.

Methylation of the ribosomal RNA gene promoter is associated with aging and age-related decline.

D'Aquila P, Montesanto A, Mandalà M, Garasto S, Mari V, Corsonello A, Bellizzi D, Passarino G.

Aging Cell. 2017 Oct;16(5):966-975. doi: 10.1111/acel.12603. Epub 2017 Jun 17.

26.

Demographic, genetic and phenotypic characteristics of centenarians in Italy: Focus on gender differences.

Montesanto A, De Rango F, Pirazzini C, Guidarelli G, Domma F, Franceschi C, Passarino G.

Mech Ageing Dev. 2017 Jul;165(Pt B):68-74. doi: 10.1016/j.mad.2017.04.008. Epub 2017 Apr 29. Review.

PMID:
28461103
27.

Estradiol via estrogen receptor beta influences ROS levels through the transcriptional regulation of SIRT3 in human seminoma TCam-2 cells.

Panza S, Santoro M, De Amicis F, Morelli C, Passarelli V, D'Aquila P, Giordano F, Cione E, Passarino G, Bellizzi D, Aquila S.

Tumour Biol. 2017 May;39(5):1010428317701642. doi: 10.1177/1010428317701642.

PMID:
28459202
28.

The genetics of human longevity: an intricacy of genes, environment, culture and microbiome.

Dato S, Rose G, Crocco P, Monti D, Garagnani P, Franceschi C, Passarino G.

Mech Ageing Dev. 2017 Jul;165(Pt B):147-155. doi: 10.1016/j.mad.2017.03.011. Epub 2017 Apr 5. Review.

PMID:
28390822
29.

Thyroid hormones in extreme longevity.

Garasto S, Montesanto A, Corsonello A, Lattanzio F, Fusco S, Passarino G, Prestipino Giarritta V, Corica F.

Mech Ageing Dev. 2017 Jul;165(Pt B):98-106. doi: 10.1016/j.mad.2017.03.002. Epub 2017 Mar 9. Review.

PMID:
28286215
30.

Pleiotropic effects of UCP2-UCP3 variability on leucocyte telomere length and glucose homeostasis.

Dato S, De Rango F, Crocco P, Passarino G, Rose G.

Biogerontology. 2017 Jun;18(3):347-355. doi: 10.1007/s10522-017-9690-z. Epub 2017 Mar 9.

PMID:
28281015
31.

Centenarians as extreme phenotypes: An ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases.

Giuliani C, Pirazzini C, Delledonne M, Xumerle L, Descombes P, Marquis J, Mengozzi G, Monti D, Bellizzi D, Passarino G, Luiselli D, Franceschi C, Garagnani P.

Mech Ageing Dev. 2017 Jul;165(Pt B):195-201. doi: 10.1016/j.mad.2017.02.007. Epub 2017 Feb 27. Review.

PMID:
28242236
32.

The methylation of nuclear and mitochondrial DNA in ageing phenotypes and longevity.

Bacalini MG, D'Aquila P, Marasco E, Nardini C, Montesanto A, Franceschi C, Passarino G, Garagnani P, Bellizzi D.

Mech Ageing Dev. 2017 Jul;165(Pt B):156-161. doi: 10.1016/j.mad.2017.01.006. Epub 2017 Jan 20. Review.

PMID:
28115210
33.

SIRT1-SIRT3 Axis Regulates Cellular Response to Oxidative Stress and Etoposide.

Carnevale I, Pellegrini L, D'Aquila P, Saladini S, Lococo E, Polletta L, Vernucci E, Foglio E, Coppola S, Sansone L, Passarino G, Bellizzi D, Russo MA, Fini M, Tafani M.

J Cell Physiol. 2017 Jul;232(7):1835-1844. doi: 10.1002/jcp.25711. Epub 2017 Jan 6.

PMID:
27925196
34.

Epigenetic modifications in multiple myeloma: recent advances on the role of DNA and histone methylation.

Amodio N, D'Aquila P, Passarino G, Tassone P, Bellizzi D.

Expert Opin Ther Targets. 2017 Jan;21(1):91-101. Review.

PMID:
27892767
35.

Mitochondrial genome and epigenome: two sides of the same coin.

D'Aquila P, Montesanto A, Guarasci F, Passarino G, Bellizzi D.

Front Biosci (Landmark Ed). 2017 Jan 1;22:888-908. Review.

PMID:
27814653
36.

Contribution of polymorphic variation of inositol hexakisphosphate kinase 3 (IP6K3) gene promoter to the susceptibility to late onset Alzheimer's disease.

Crocco P, Saiardi A, Wilson MS, Maletta R, Bruni AC, Passarino G, Rose G.

Biochim Biophys Acta. 2016 Sep;1862(9):1766-73. doi: 10.1016/j.bbadis.2016.06.014. Epub 2016 Jun 21.

37.

Nutrigerontology: a key for achieving successful ageing and longevity.

Aiello A, Accardi G, Candore G, Carruba G, Davinelli S, Passarino G, Scapagnini G, Vasto S, Caruso C.

Immun Ageing. 2016 May 21;13:17. doi: 10.1186/s12979-016-0071-2. eCollection 2016.

38.

Human longevity: Genetics or Lifestyle? It takes two to tango.

Passarino G, De Rango F, Montesanto A.

Immun Ageing. 2016 Apr 5;13:12. doi: 10.1186/s12979-016-0066-z. eCollection 2016. Review.

39.

Association of the Laminin, Alpha 5 (LAMA5) rs4925386 with height and longevity in an elderly population from Southern Italy.

De Luca M, Crocco P, De Rango F, Passarino G, Rose G.

Mech Ageing Dev. 2016 Apr;155:55-9. doi: 10.1016/j.mad.2016.03.003. Epub 2016 Mar 9.

PMID:
26968355
40.

The Genetic Variability of UCP4 Affects the Individual Susceptibility to Late-Onset Alzheimer's Disease and Modifies the Disease's Risk in APOE-ɛ4 Carriers.

Montesanto A, Crocco P, Anfossi M, Smirne N, Puccio G, Colao R, Maletta R, Passarino G, Bruni AC, Rose G.

J Alzheimers Dis. 2016;51(4):1265-74. doi: 10.3233/JAD-150993.

PMID:
26923023
41.

The impact of nutrients on the aging rate: A complex interaction of demographic, environmental and genetic factors.

Dato S, Bellizzi D, Rose G, Passarino G.

Mech Ageing Dev. 2016 Mar;154:49-61. doi: 10.1016/j.mad.2016.02.005. Epub 2016 Feb 10. Review.

PMID:
26876763
42.

miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth.

Fulciniti M, Amodio N, Bandi RL, Cagnetta A, Samur MK, Acharya C, Prabhala R, D'Aquila P, Bellizzi D, Passarino G, Adamia S, Neri A, Hunter ZR, Treon SP, Anderson KC, Tassone P, Munshi NC.

Blood Cancer J. 2016 Jan 15;6:e380. doi: 10.1038/bcj.2015.106.

43.

The Standard Model from LHC to future colliders.

Forte S, Nisati A, Passarino G, Tenchini R, Calame CM, Chiesa M, Cobal M, Corcella G, Degrassi G, Ferrera G, Magnea L, Maltoni F, Montagna G, Nason P, Nicrosini O, Oleari C, Piccinini F, Riva F, Vicini A.

Eur Phys J C Part Fields. 2015;75(11):554. Epub 2015 Nov 25.

44.

Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring.

Horvath S, Pirazzini C, Bacalini MG, Gentilini D, Di Blasio AM, Delledonne M, Mari D, Arosio B, Monti D, Passarino G, De Rango F, D'Aquila P, Giuliani C, Marasco E, Collino S, Descombes P, Garagnani P, Franceschi C.

Aging (Albany NY). 2015 Dec;7(12):1159-70.

45.

Age-and gender-related pattern of methylation in the MT-RNR1 gene.

D'Aquila P, Giordano M, Montesanto A, De Rango F, Passarino G, Bellizzi D.

Epigenomics. 2015 Aug;7(5):707-16. doi: 10.2217/epi.15.30. Epub 2015 Sep 7.

PMID:
26343273
46.

Metabolism and successful aging: Polymorphic variation of syndecan-4 (SDC4) gene associate with longevity and lipid profile in healthy elderly Italian subjects.

Rose G, Crocco P, De Rango F, Corsonello A, Lattanzio F, De Luca M, Passarino G.

Mech Ageing Dev. 2015 Sep;150:27-33. doi: 10.1016/j.mad.2015.08.003. Epub 2015 Aug 5.

PMID:
26254886
47.

Antioxidants and Quality of Aging: Further Evidences for a Major Role of TXNRD1 Gene Variability on Physical Performance at Old Age.

Dato S, De Rango F, Crocco P, Passarino G, Rose G.

Oxid Med Cell Longev. 2015;2015:926067. doi: 10.1155/2015/926067. Epub 2015 Apr 29.

48.

Disentangling the Impact of Chronic Kidney Disease, Anemia, and Mobility Limitation on Mortality in Older Patients Discharged From Hospital.

Lattanzio F, Corsonello A, Montesanto A, Abbatecola AM, Lofaro D, Passarino G, Fusco S, Corica F, Pedone C, Maggio M, Volpato S, Incalzi RA.

J Gerontol A Biol Sci Med Sci. 2015 Sep;70(9):1120-7. doi: 10.1093/gerona/glv068. Epub 2015 May 19.

PMID:
25991829
49.

Polymorphisms Falling Within Putative miRNA Target Sites in the 3'UTR Region of SIRT2 and DRD2 Genes Are Correlated With Human Longevity.

Crocco P, Montesanto A, Passarino G, Rose G.

J Gerontol A Biol Sci Med Sci. 2016 May;71(5):586-92. doi: 10.1093/gerona/glv058. Epub 2015 May 2.

PMID:
25934993
50.

Interventions to Slow Aging in Humans: Are We Ready?

Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L.

Aging Cell. 2015 Aug;14(4):497-510. doi: 10.1111/acel.12338. Epub 2015 Apr 22. Review.

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