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Items: 1 to 50 of 87

1.

Identification of Cross Talk between FoxM1 and RASSF1A as a Therapeutic Target of Colon Cancer.

Blanchard TG, Czinn SJ, Banerjee V, Sharda N, Bafford AC, Mubariz F, Morozov D, Passaniti A, Ahmed H, Banerjee A.

Cancers (Basel). 2019 Feb 8;11(2). pii: E199. doi: 10.3390/cancers11020199.

2.

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity.

Kim MS, Gernapudi R, Choi EY, Lapidus RG, Passaniti A.

Oncotarget. 2017 Aug 10;8(41):70916-70940. doi: 10.18632/oncotarget.20200. eCollection 2017 Sep 19.

3.

Roles of RUNX in Hippo Pathway Signaling.

Passaniti A, Brusgard JL, Qiao Y, Sudol M, Finch-Edmondson M.

Adv Exp Med Biol. 2017;962:435-448. doi: 10.1007/978-981-10-3233-2_26. Review.

PMID:
28299672
4.

Metabolic targets for potential prostate cancer therapeutics.

Twum-Ampofo J, Fu DX, Passaniti A, Hussain A, Siddiqui MM.

Curr Opin Oncol. 2016 May;28(3):241-7. doi: 10.1097/CCO.0000000000000276. Review.

PMID:
26907571
5.

A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-kB regulates head and neck squamous cell carcinoma proliferation.

Li Z, Yang Z, Passaniti A, Lapidus RG, Liu X, Cullen KJ, Dan HC.

Oncotarget. 2016 May 31;7(22):31892-906. doi: 10.18632/oncotarget.7441.

6.

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells.

Brusgard JL, Choe M, Chumsri S, Renoud K, MacKerell AD Jr, Sudol M, Passaniti A.

Oncotarget. 2015 Sep 29;6(29):28132-50. doi: 10.18632/oncotarget.4654.

7.

The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells.

Choe M, Brusgard JL, Chumsri S, Bhandary L, Zhao XF, Lu S, Goloubeva OG, Polster BM, Fiskum GM, Girnun GD, Kim MS, Passaniti A.

J Cell Biochem. 2015 Oct;116(10):2210-26. doi: 10.1002/jcb.25171.

8.

α1-acid glycoprotein disrupts capillary-like tube formation of human lung microvascular endothelia.

Miranda-Ribera A, Passaniti A, Ceciliani F, Goldblum SE.

Exp Lung Res. 2014 Dec;40(10):507-19. doi: 10.3109/01902148.2014.956945. Epub 2014 Oct 16.

PMID:
25322067
9.

Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells.

Mochin MT, Underwood KF, Cooper B, McLenithan JC, Pierce AD, Nalvarte C, Arbiser J, Karlsson AI, Moise AR, Moskovitz J, Passaniti A.

Microvasc Res. 2015 Jan;97:55-64. doi: 10.1016/j.mvr.2014.09.008. Epub 2014 Oct 2.

10.

Human airway epithelia express catalytically active NEU3 sialidase.

Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Sun W, Luzina IG, Webb TJ, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE.

Am J Physiol Lung Cell Mol Physiol. 2014 May 1;306(9):L876-86. doi: 10.1152/ajplung.00322.2013. Epub 2014 Mar 21.

11.

NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia.

Lee C, Liu A, Miranda-Ribera A, Hyun SW, Lillehoj EP, Cross AS, Passaniti A, Grimm PR, Kim BY, Welling PA, Madri JA, DeLisser HM, Goldblum SE.

J Biol Chem. 2014 Mar 28;289(13):9121-35. doi: 10.1074/jbc.M114.555888. Epub 2014 Feb 18.

12.

A quantitative assay to study protein:DNA interactions, discover transcriptional regulators of gene expression, and identify novel anti-tumor agents.

Underwood KF, Mochin MT, Brusgard JL, Choe M, Gnatt A, Passaniti A.

J Vis Exp. 2013 Aug 31;(78). doi: 10.3791/50512.

13.

Vitamin D3 insufficiency and colorectal cancer.

Di Rosa M, Malaguarnera M, Zanghì A, Passaniti A, Malaguarnera L.

Crit Rev Oncol Hematol. 2013 Dec;88(3):594-612. doi: 10.1016/j.critrevonc.2013.07.016. Epub 2013 Aug 12. Review.

PMID:
23941729
14.

NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does not.

Cross AS, Hyun SW, Miranda-Ribera A, Feng C, Liu A, Nguyen C, Zhang L, Luzina IG, Atamas SP, Twaddell WS, Guang W, Lillehoj EP, Puché AC, Huang W, Wang LX, Passaniti A, Goldblum SE.

J Biol Chem. 2012 May 4;287(19):15966-80. doi: 10.1074/jbc.M112.346817. Epub 2012 Mar 8.

15.

NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signaling.

Lillehoj EP, Hyun SW, Feng C, Zhang L, Liu A, Guang W, Nguyen C, Luzina IG, Atamas SP, Passaniti A, Twaddell WS, Puché AC, Wang LX, Cross AS, Goldblum SE.

J Biol Chem. 2012 Mar 9;287(11):8214-31. doi: 10.1074/jbc.M111.292888. Epub 2012 Jan 13.

16.

Regulation of RUNX2 transcription factor-DNA interactions and cell proliferation by vitamin D3 (cholecalciferol) prohormone activity.

Underwood KF, D'Souza DR, Mochin-Peters M, Pierce AD, Kommineni S, Choe M, Bennett J, Gnatt A, Habtemariam B, MacKerell AD Jr, Passaniti A.

J Bone Miner Res. 2012 Apr;27(4):913-25. doi: 10.1002/jbmr.1504.

17.

Glucose-activated RUNX2 phosphorylation promotes endothelial cell proliferation and an angiogenic phenotype.

Pierce AD, Anglin IE, Vitolo MI, Mochin MT, Underwood KF, Goldblum SE, Kommineni S, Passaniti A.

J Cell Biochem. 2012 Jan;113(1):282-92. doi: 10.1002/jcb.23354.

18.

Diverse injurious stimuli reduce protein tyrosine phosphatase-μ expression and enhance epidermal growth factor receptor signaling in human airway epithelia.

Hyun SW, Anglin IE, Liu A, Yang S, Sorkin JD, Lillehoj E, Tonks NK, Passaniti A, Goldblum SE.

Exp Lung Res. 2011 Aug;37(6):327-43. doi: 10.3109/01902148.2011.566673. Epub 2011 Jun 7.

19.

ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer.

Zhang Y, Ali TZ, Zhou H, D'Souza DR, Lu Y, Jaffe J, Liu Z, Passaniti A, Hamburger AW.

Cancer Res. 2010 Jan 1;70(1):240-8. doi: 10.1158/0008-5472.CAN-09-2904.

20.

Hyperglycemia regulates RUNX2 activation and cellular wound healing through the aldose reductase polyol pathway.

D'Souza DR, Salib MM, Bennett J, Mochin-Peters M, Asrani K, Goldblum SE, Renoud KJ, Shapiro P, Passaniti A.

J Biol Chem. 2009 Jul 3;284(27):17947-55. doi: 10.1074/jbc.M109.002378. Epub 2009 Apr 21.

21.

Epidermal growth factor-like repeats of thrombospondins activate phospholipase Cgamma and increase epithelial cell migration through indirect epidermal growth factor receptor activation.

Liu A, Garg P, Yang S, Gong P, Pallero MA, Annis DS, Liu Y, Passaniti A, Mann D, Mosher DF, Murphy-Ullrich JE, Goldblum SE.

J Biol Chem. 2009 Mar 6;284(10):6389-402. doi: 10.1074/jbc.M809198200. Epub 2009 Jan 7.

22.

The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation.

Vitolo MI, Anglin IE, Mahoney WM Jr, Renoud KJ, Gartenhaus RB, Bachman KE, Passaniti A.

Cancer Biol Ther. 2007 Jun;6(6):856-63. Epub 2007 Mar 1.

PMID:
17438369
23.

Induced JunD in intestinal epithelial cells represses CDK4 transcription through its proximal promoter region following polyamine depletion.

Xiao L, Rao JN, Zou T, Liu L, Marasa BS, Chen J, Turner DJ, Passaniti A, Wang JY.

Biochem J. 2007 May 1;403(3):573-81.

24.

TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia.

Angelini DJ, Hyun SW, Grigoryev DN, Garg P, Gong P, Singh IS, Passaniti A, Hasday JD, Goldblum SE.

Am J Physiol Lung Cell Mol Physiol. 2006 Dec;291(6):L1232-45. Epub 2006 Aug 4.

25.

Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain.

Sun L, Hui AM, Su Q, Vortmeyer A, Kotliarov Y, Pastorino S, Passaniti A, Menon J, Walling J, Bailey R, Rosenblum M, Mikkelsen T, Fine HA.

Cancer Cell. 2006 Apr;9(4):287-300.

26.

Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation.

Qiao M, Shapiro P, Fosbrink M, Rus H, Kumar R, Passaniti A.

J Biol Chem. 2006 Mar 17;281(11):7118-28. Epub 2006 Jan 9.

27.

Phase I and pharmacokinetic study of flavopiridol followed by 1-beta-D-arabinofuranosylcytosine and mitoxantrone in relapsed and refractory adult acute leukemias.

Karp JE, Passaniti A, Gojo I, Kaufmann S, Bible K, Garimella TS, Greer J, Briel J, Smith BD, Gore SD, Tidwell ML, Ross DD, Wright JJ, Colevas AD, Bauer KS.

Clin Cancer Res. 2005 Dec 1;11(23):8403-12.

28.

Receptor protein tyrosine phosphatase micro regulates the paracellular pathway in human lung microvascular endothelia.

Sui XF, Kiser TD, Hyun SW, Angelini DJ, Del Vecchio RL, Young BA, Hasday JD, Romer LH, Passaniti A, Tonks NK, Goldblum SE.

Am J Pathol. 2005 Apr;166(4):1247-58.

30.

Anti-angiogenic activity of inositol hexaphosphate (IP6).

Vucenik I, Passaniti A, Vitolo MI, Tantivejkul K, Eggleton P, Shamsuddin AM.

Carcinogenesis. 2004 Nov;25(11):2115-23. Epub 2004 Aug 5.

PMID:
15297368
31.

Runx protein signaling in human cancers.

Anglin I, Passaniti A.

Cancer Treat Res. 2004;119:189-215. Review. No abstract available.

PMID:
15164879
32.

Regulation of TGFbeta1-mediated growth inhibition and apoptosis by RUNX2 isoforms in endothelial cells.

Sun L, Vitolo MI, Qiao M, Anglin IE, Passaniti A.

Oncogene. 2004 Jun 10;23(27):4722-34.

PMID:
15107836
33.

Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells.

Uren A, Merchant MS, Sun CJ, Vitolo MI, Sun Y, Tsokos M, Illei PB, Ladanyi M, Passaniti A, Mackall C, Toretsky JA.

Oncogene. 2003 Apr 17;22(15):2334-42.

PMID:
12700668
34.

Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.

Young BA, Sui X, Kiser TD, Hyun SW, Wang P, Sakarya S, Angelini DJ, Schaphorst KL, Hasday JD, Cross AS, Romer LH, Passaniti A, Goldblum SE.

Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L63-75. Epub 2003 Mar 7.

35.
36.

Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 activity.

Park JW, Choi YJ, Suh SI, Baek WK, Suh MH, Jin IN, Min DS, Woo JH, Chang JS, Passaniti A, Lee YH, Kwon TK.

Carcinogenesis. 2001 Oct;22(10):1633-9.

PMID:
11577002
37.
38.

Telomerized human microvasculature is functional in vivo.

Yang J, Nagavarapu U, Relloma K, Sjaastad MD, Moss WC, Passaniti A, Herron GS.

Nat Biotechnol. 2001 Mar;19(3):219-24.

PMID:
11231553
39.

p53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization.

Park JW, Jang MA, Lee YH, Passaniti A, Kwon TK.

Biochem Biophys Res Commun. 2001 Jan 12;280(1):244-8.

PMID:
11162506
40.
41.
42.

Vanadate and the absence of myofibroblasts in wound contraction.

Ehrlich HP, Keefer KA, Myers RL, Passaniti A.

Arch Surg. 1999 May;134(5):494-501.

PMID:
10323421
43.
44.

Hypomethylation of an exon I estrogen receptor CpG island in spontaneous and carcinogen-induced mammary tumorigenesis in the rat.

Yenbutr P, Hilakivi-Clarke L, Passaniti A.

Mech Ageing Dev. 1998 Dec 1;106(1-2):93-102.

PMID:
9883975
45.

An in vivo angiogenesis assay to study positive and negative regulators of neovascularization.

Capogrossi MC, Passaniti A.

Methods Mol Med. 1999;30:367-84. doi: 10.1385/1-59259-247-3:367.

PMID:
21341040
46.

Adenovirus-mediated wild-type p53 overexpression inhibits endothelial cell differentiation in vitro and angiogenesis in vivo.

Riccioni T, Cirielli C, Wang X, Passaniti A, Capogrossi MC.

Gene Ther. 1998 Jun;5(6):747-54.

49.

Adenovirus-mediated gene transfer of fibroblast growth factor-1: angiogenesis and tumorigenicity in nude mice.

Pili R, Chang J, Muhlhauser J, Crystal RG, Capogrossi MC, Passaniti A.

Int J Cancer. 1997 Oct 9;73(2):258-63.

50.

Anti-tumor gene therapy.

Cirielli C, Capogrossi MC, Passaniti A.

J Neurooncol. 1997 Jan;31(1-2):217-23. Review.

PMID:
9049851

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