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Items: 1 to 50 of 67

1.

Insights Into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia From Engineered Human Heart Tissue.

Park SJ, Zhang D, Qi Y, Li Y, Lee KY, Bezzerides VJ, Yang P, Xia S, Kim SL, Liu X, Lu F, Pasqualini FS, Campbell PH, Geva J, Roberts AE, Kleber AG, Abrams DJ, Pu WT, Parker KK.

Circulation. 2019 Jul 30;140(5):390-404. doi: 10.1161/CIRCULATIONAHA.119.039711. Epub 2019 Jul 17.

PMID:
31311300
2.

Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors.

Ponzetta A, Carriero R, Carnevale S, Barbagallo M, Molgora M, Perucchini C, Magrini E, Gianni F, Kunderfranco P, Polentarutti N, Pasqualini F, Di Marco S, Supino D, Peano C, Cananzi F, Colombo P, Pilotti S, Alomar SY, Bonavita E, Galdiero MR, Garlanda C, Mantovani A, Jaillon S.

Cell. 2019 Jul 11;178(2):346-360.e24. doi: 10.1016/j.cell.2019.05.047. Epub 2019 Jun 27.

3.

IL1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development.

Riva F, Ponzoni M, Supino D, Bertilaccio MTS, Polentarutti N, Massara M, Pasqualini F, Carriero R, Innocenzi A, Anselmo A, Veliz-Rodriguez T, Simonetti G, Anders HJ, Caligaris-Cappio F, Mantovani A, Muzio M, Garlanda C.

Cancer Immunol Res. 2019 Jun;7(6):874-885. doi: 10.1158/2326-6066.CIR-18-0698. Epub 2019 Apr 24.

PMID:
31018956
4.

A tissue-engineered scale model of the heart ventricle.

MacQueen LA, Sheehy SP, Chantre CO, Zimmerman JF, Pasqualini FS, Liu X, Goss JA, Campbell PH, Gonzalez GM, Park SJ, Capulli AK, Ferrier JP, Kosar TF, Mahadevan L, Pu WT, Parker KK.

Nat Biomed Eng. 2018 Dec;2(12):930-941. doi: 10.1038/s41551-018-0271-5. Epub 2018 Jul 23.

PMID:
31015723
5.

Traction force microscopy of engineered cardiac tissues.

Pasqualini FS, Agarwal A, O'Connor BB, Liu Q, Sheehy SP, Parker KK.

PLoS One. 2018 Mar 28;13(3):e0194706. doi: 10.1371/journal.pone.0194706. eCollection 2018.

6.

Protumor Steering of Cancer Inflammation by p50 NF-κB Enhances Colorectal Cancer Progression.

Porta C, Ippolito A, Consonni FM, Carraro L, Celesti G, Correale C, Grizzi F, Pasqualini F, Tartari S, Rinaldi M, Bianchi P, Balzac F, Vetrano S, Turco E, Hirsch E, Laghi L, Sica A.

Cancer Immunol Res. 2018 May;6(5):578-593. doi: 10.1158/2326-6066.CIR-17-0036. Epub 2018 Mar 27.

7.

The atypical chemokine receptor ACKR2 drives pulmonary fibrosis by tuning influx of CCR2+ and CCR5+ IFNγ-producing γδT cells in mice.

Russo RC, Savino B, Mirolo M, Buracchi C, Germano G, Anselmo A, Zammataro L, Pasqualini F, Mantovani A, Locati M, Teixeira MM.

Am J Physiol Lung Cell Mol Physiol. 2018 Jun 1;314(6):L1010-L1025. doi: 10.1152/ajplung.00233.2017. Epub 2018 Feb 22.

8.

Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition.

Siddiqui I, Erreni M, Kamal MA, Porta C, Marchesi F, Pesce S, Pasqualini F, Schiarea S, Chiabrando C, Mantovani A, Allavena P.

Oncoimmunology. 2017 Nov 1;7(2):e1388485. doi: 10.1080/2162402X.2017.1388485. eCollection 2018.

9.

Translational cardiac stem cell therapy: advancing from first-generation to next-generation cell types.

Cambria E, Pasqualini FS, Wolint P, Günter J, Steiger J, Bopp A, Hoerstrup SP, Emmert MY.

NPJ Regen Med. 2017 Jun 13;2:17. doi: 10.1038/s41536-017-0024-1. eCollection 2017. Review.

10.

GADD45β Loss Ablates Innate Immunosuppression in Cancer.

Verzella D, Bennett J, Fischietti M, Thotakura AK, Recordati C, Pasqualini F, Capece D, Vecchiotti D, D'Andrea D, Di Francesco B, De Maglie M, Begalli F, Tornatore L, Papa S, Lawrence T, Forbes SJ, Sica A, Alesse E, Zazzeroni F, Franzoso G.

Cancer Res. 2018 Mar 1;78(5):1275-1292. doi: 10.1158/0008-5472.CAN-17-1833. Epub 2017 Dec 26.

11.

Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer.

Rubino M, Kunderfranco P, Basso G, Greco CM, Pasqualini F, Serio S, Roncalli M, Laghi L, Mantovani A, Papait R, Garlanda C.

Oncoimmunology. 2017 May 30;6(7):e1333215. doi: 10.1080/2162402X.2017.1333215. eCollection 2017.

12.

High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity.

Campesato LF, Silva APM, Cordeiro L, Correa BR, Navarro FCP, Zanin RF, Marçola M, Inoue LT, Duarte ML, Molgora M, Pasqualini F, Massara M, Galante P, Barroso-Sousa R, Polentarutti N, Riva F, Costa ET, Mantovani A, Garlanda C, Camargo AA.

Oncotarget. 2017 Jul 25;8(30):49470-49483. doi: 10.18632/oncotarget.17713.

13.

JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement.

Capulli AK, Emmert MY, Pasqualini FS, Kehl D, Caliskan E, Lind JU, Sheehy SP, Park SJ, Ahn S, Weber B, Goss JA, Hoerstrup SP, Parker KK.

Biomaterials. 2017 Jul;133:229-241. doi: 10.1016/j.biomaterials.2017.04.033. Epub 2017 Apr 18.

14.

Safety and efficacy of cardiopoietic stem cells in the treatment of post-infarction left-ventricular dysfunction - From cardioprotection to functional repair in a translational pig infarction model.

Emmert MY, Wolint P, Jakab A, Sheehy SP, Pasqualini FS, Nguyen TDL, Hilbe M, Seifert B, Weber B, Brokopp CE, Macejovska D, Caliskan E, von Eckardstein A, Schwartlander R, Vogel V, Falk V, Parker KK, Gyöngyösi M, Hoerstrup SP.

Biomaterials. 2017 Apr;122:48-62. doi: 10.1016/j.biomaterials.2016.11.029. Epub 2016 Nov 23.

PMID:
28107664
15.

Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.

Pasqualini FS, Nesmith AP, Horton RE, Sheehy SP, Parker KK.

Biomed Res Int. 2016;2016:4081638. doi: 10.1155/2016/4081638. Epub 2016 Dec 4. Review.

16.

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation.

Dander E, De Lorenzo P, Bottazzi B, Quarello P, Vinci P, Balduzzi A, Masciocchi F, Bonanomi S, Cappuzzello C, Prunotto G, Pavan F, Pasqualini F, Sironi M, Cuccovillo I, Leone R, Salvatori G, Parma M, Terruzzi E, Pagni F, Locatelli F, Mantovani A, Fagioli F, Biondi A, Garlanda C, Valsecchi MG, Rovelli A, D'Amico G.

Oncotarget. 2016 Dec 13;7(50):82123-82138. doi: 10.18632/oncotarget.13488.

17.

Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing.

Lind JU, Busbee TA, Valentine AD, Pasqualini FS, Yuan H, Yadid M, Park SJ, Kotikian A, Nesmith AP, Campbell PH, Vlassak JJ, Lewis JA, Parker KK.

Nat Mater. 2017 Mar;16(3):303-308. doi: 10.1038/nmat4782. Epub 2016 Oct 24.

18.

Heart Valve Replacements with Regenerative Capacity.

Dijkman PE, Fioretta ES, Frese L, Pasqualini FS, Hoerstrup SP.

Transfus Med Hemother. 2016 Jul;43(4):282-290. Epub 2016 Jul 26. Review.

19.

Organ Chips: Quality Assurance Systems in Regenerative Medicine.

Pasqualini FS, Emmert MY, Parker KK, Hoerstrup SP.

Clin Pharmacol Ther. 2017 Jan;101(1):31-34. doi: 10.1002/cpt.527. Epub 2016 Nov 21.

20.

A human in vitro model of Duchenne muscular dystrophy muscle formation and contractility.

Nesmith AP, Wagner MA, Pasqualini FS, O'Connor BB, Pincus MJ, August PR, Parker KK.

J Cell Biol. 2016 Oct 10;215(1):47-56. Epub 2016 Oct 3.

21.

Phototactic guidance of a tissue-engineered soft-robotic ray.

Park SJ, Gazzola M, Park KS, Park S, Di Santo V, Blevins EL, Lind JU, Campbell PH, Dauth S, Capulli AK, Pasqualini FS, Ahn S, Cho A, Yuan H, Maoz BM, Vijaykumar R, Choi JW, Deisseroth K, Lauder GV, Mahadevan L, Parker KK.

Science. 2016 Jul 8;353(6295):158-62. doi: 10.1126/science.aaf4292.

22.

Functional TRAIL receptors in monocytes and tumor-associated macrophages: A possible targeting pathway in the tumor microenvironment.

Liguori M, Buracchi C, Pasqualini F, Bergomas F, Pesce S, Sironi M, Grizzi F, Mantovani A, Belgiovine C, Allavena P.

Oncotarget. 2016 Jul 5;7(27):41662-41676. doi: 10.18632/oncotarget.9340.

23.

Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy.

Aratyn-Schaus Y, Pasqualini FS, Yuan H, McCain ML, Ye GJ, Sheehy SP, Campbell PH, Parker KK.

J Cell Biol. 2016 Feb 15;212(4):389-97. doi: 10.1083/jcb.201508026. Epub 2016 Feb 8.

24.

Angiotensin II Induced Cardiac Dysfunction on a Chip.

Horton RE, Yadid M, McCain ML, Sheehy SP, Pasqualini FS, Park SJ, Cho A, Campbell P, Parker KK.

PLoS One. 2016 Jan 25;11(1):e0146415. doi: 10.1371/journal.pone.0146415. eCollection 2016.

25.

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling.

Cappuzzello C, Doni A, Dander E, Pasqualini F, Nebuloni M, Bottazzi B, Mantovani A, Biondi A, Garlanda C, D'Amico G.

J Invest Dermatol. 2016 Jan;136(1):293-300. doi: 10.1038/JID.2015.346.

26.

Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy.

Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O'Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M.

Nat Commun. 2015 Nov 6;6:8803. doi: 10.1038/ncomms9803.

27.

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling.

Cappuzzello C, Doni A, Dander E, Pasqualini F, Nebuloni M, Bottazzi B, Mantovani A, Biondi A, Garlanda C, D'Amico G.

J Invest Dermatol. 2015 Sep 3. doi: 10.1038/jid.2015.346. [Epub ahead of print]

PMID:
26340034
28.

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode.

Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Castagnoli C, Cambieri I, Stravalaci M, Pasqualini F, Laface I, Valentino S, Tartari S, Ponzetta A, Maina V, Barbieri SS, Tremoli E, Catapano AL, Norata GD, Bottazzi B, Garlanda C, Mantovani A.

J Exp Med. 2015 Jun 1;212(6):905-25. doi: 10.1084/jem.20141268. Epub 2015 May 11.

29.

Structural phenotyping of stem cell-derived cardiomyocytes.

Pasqualini FS, Sheehy SP, Agarwal A, Aratyn-Schaus Y, Parker KK.

Stem Cell Reports. 2015 Mar 10;4(3):340-7. doi: 10.1016/j.stemcr.2015.01.020. Epub 2015 Feb 26.

30.

PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer.

Bonavita E, Gentile S, Rubino M, Maina V, Papait R, Kunderfranco P, Greco C, Feruglio F, Molgora M, Laface I, Tartari S, Doni A, Pasqualini F, Barbati E, Basso G, Galdiero MR, Nebuloni M, Roncalli M, Colombo P, Laghi L, Lambris JD, Jaillon S, Garlanda C, Mantovani A.

Cell. 2015 Feb 12;160(4):700-714. doi: 10.1016/j.cell.2015.01.004.

31.

Origin of cardiomyocytes in the adult heart.

Leri A, Rota M, Pasqualini FS, Goichberg P, Anversa P.

Circ Res. 2015 Jan 2;116(1):150-66. doi: 10.1161/CIRCRESAHA.116.303595. Review. Erratum in: Circ Res. 2015 Dec 4;117(12):e133.

32.

ERK-dependent downregulation of the atypical chemokine receptor D6 drives tumor aggressiveness in Kaposi sarcoma.

Savino B, Caronni N, Anselmo A, Pasqualini F, Borroni EM, Basso G, Celesti G, Laghi L, Tourlaki A, Boneschi V, Brambilla L, Nebuloni M, Vago G, Mantovani A, Locati M, Bonecchi R.

Cancer Immunol Res. 2014 Jul;2(7):679-89. doi: 10.1158/2326-6066.CIR-13-0202. Epub 2014 Apr 2.

33.

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.

Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, Wang DZ, Li K, Wang J, Wanders RJ, Kulik W, Vaz FM, Laflamme MA, Murry CE, Chien KR, Kelley RI, Church GM, Parker KK, Pu WT.

Nat Med. 2014 Jun;20(6):616-23. doi: 10.1038/nm.3545. Epub 2014 May 11.

34.

Matrix elasticity regulates the optimal cardiac myocyte shape for contractility.

McCain ML, Yuan H, Pasqualini FS, Campbell PH, Parker KK.

Am J Physiol Heart Circ Physiol. 2014 Jun 1;306(11):H1525-39. doi: 10.1152/ajpheart.00799.2013. Epub 2014 Mar 28.

35.

Quality metrics for stem cell-derived cardiac myocytes.

Sheehy SP, Pasqualini F, Grosberg A, Park SJ, Aratyn-Schaus Y, Parker KK.

Stem Cell Reports. 2014 Mar 6;2(3):282-94. doi: 10.1016/j.stemcr.2014.01.015. eCollection 2014 Mar 11.

36.

The contractile strength of vascular smooth muscle myocytes is shape dependent.

Ye GJ, Aratyn-Schaus Y, Nesmith AP, Pasqualini FS, Alford PW, Parker KK.

Integr Biol (Camb). 2014 Feb;6(2):152-63. doi: 10.1039/c3ib40230d.

PMID:
24406783
37.

Role of macrophage targeting in the antitumor activity of trabectedin.

Germano G, Frapolli R, Belgiovine C, Anselmo A, Pesce S, Liguori M, Erba E, Uboldi S, Zucchetti M, Pasqualini F, Nebuloni M, van Rooijen N, Mortarini R, Beltrame L, Marchini S, Fuso Nerini I, Sanfilippo R, Casali PG, Pilotti S, Galmarini CM, Anichini A, Mantovani A, D'Incalci M, Allavena P.

Cancer Cell. 2013 Feb 11;23(2):249-62. doi: 10.1016/j.ccr.2013.01.008.

38.

Response of CFTR-deficient mice to long-term chronic Pseudomonas aeruginosa infection and PTX3 therapy.

Paroni M, Moalli F, Nebuloni M, Pasqualini F, Bonfield T, Nonis A, Mantovani A, Garlanda C, Bragonzi A.

J Infect Dis. 2013 Jul;208(1):130-8. doi: 10.1093/infdis/jis636. Epub 2012 Oct 18.

39.

Anti-phospholipid induced murine fetal loss: novel protective effect of a peptide targeting the β2 glycoprotein I phospholipid-binding site. Implications for human fetal loss.

de la Torre YM, Pregnolato F, D'Amelio F, Grossi C, Di Simone N, Pasqualini F, Nebuloni M, Chen P, Pierangeli S, Bassani N, Ambrogi F, Borghi MO, Vecchi A, Locati M, Meroni PL.

J Autoimmun. 2012 May;38(2-3):J209-15. doi: 10.1016/j.jaut.2011.11.009. Epub 2011 Dec 22.

40.

Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility.

Solinas G, Schiarea S, Liguori M, Fabbri M, Pesce S, Zammataro L, Pasqualini F, Nebuloni M, Chiabrando C, Mantovani A, Allavena P.

J Immunol. 2010 Jul 1;185(1):642-52. doi: 10.4049/jimmunol.1000413. Epub 2010 Jun 7.

41.

PTX3 expression in the heart tissues of patients with myocardial infarction and infectious myocarditis.

Nebuloni M, Pasqualini F, Zerbi P, Lauri E, Mantovani A, Vago L, Garlanda C.

Cardiovasc Pathol. 2011 Jan-Feb;20(1):e27-35. doi: 10.1016/j.carpath.2010.02.005. Epub 2010 Mar 30.

PMID:
20356766
42.

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.

Germano G, Frapolli R, Simone M, Tavecchio M, Erba E, Pesce S, Pasqualini F, Grosso F, Sanfilippo R, Casali PG, Gronchi A, Virdis E, Tarantino E, Pilotti S, Greco A, Nebuloni M, Galmarini CM, Tercero JC, Mantovani A, D'Incalci M, Allavena P.

Cancer Res. 2010 Mar 15;70(6):2235-44. doi: 10.1158/0008-5472.CAN-09-2335. Epub 2010 Mar 9.

43.

A novel computational model of the human ventricular action potential and Ca transient.

Grandi E, Pasqualini FS, Bers DM.

J Mol Cell Cardiol. 2010 Jan;48(1):112-21. doi: 10.1016/j.yjmcc.2009.09.019. Epub 2009 Oct 14.

44.

Deficiency of the long pentraxin PTX3 promotes vascular inflammation and atherosclerosis.

Norata GD, Marchesi P, Pulakazhi Venu VK, Pasqualini F, Anselmo A, Moalli F, Pizzitola I, Garlanda C, Mantovani A, Catapano AL.

Circulation. 2009 Aug 25;120(8):699-708. doi: 10.1161/CIRCULATIONAHA.108.806547. Epub 2009 Aug 10.

PMID:
19667236
45.

Role of the chemokine scavenger receptor D6 in balancing inflammation and immune activation.

Borroni EM, Buracchi C, Savino B, Pasqualini F, Russo RC, Nebuloni M, Bonecchi R, Mantovani A, Locati M.

Methods Enzymol. 2009;460:231-43. doi: 10.1016/S0076-6879(09)05211-2.

PMID:
19446728
46.

Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6.

Maina V, Cotena A, Doni A, Nebuloni M, Pasqualini F, Milner CM, Day AJ, Mantovani A, Garlanda C.

J Leukoc Biol. 2009 Jul;86(1):123-32. doi: 10.1189/jlb.0608345. Epub 2009 Apr 23. Erratum in: J Leukoc Biol. 2017 Feb;101(2):613.

47.

Theoretical investigation of action potential duration dependence on extracellular Ca2+ in human cardiomyocytes.

Grandi E, Pasqualini FS, Pes C, Corsi C, Zaza A, Severi S.

J Mol Cell Cardiol. 2009 Mar;46(3):332-42. doi: 10.1016/j.yjmcc.2008.12.002. Epub 2008 Dec 11.

PMID:
19121322
48.

Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and nonhematopoietic cells.

Doni A, Mantovani G, Porta C, Tuckermann J, Reichardt HM, Kleiman A, Sironi M, Rubino L, Pasqualini F, Nebuloni M, Signorini S, Peri G, Sica A, Beck-Peccoz P, Bottazzi B, Mantovani A.

J Biol Chem. 2008 Oct 31;283(44):29983-92. doi: 10.1074/jbc.M805631200. Epub 2008 Aug 14.

49.

Divergent effects of hypoxia on dendritic cell functions.

Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A.

Blood. 2008 Nov 1;112(9):3723-34. doi: 10.1182/blood-2008-02-142091. Epub 2008 Aug 11.

50.

Cardioprotective function of the long pentraxin PTX3 in acute myocardial infarction.

Salio M, Chimenti S, De Angelis N, Molla F, Maina V, Nebuloni M, Pasqualini F, Latini R, Garlanda C, Mantovani A.

Circulation. 2008 Feb 26;117(8):1055-64. doi: 10.1161/CIRCULATIONAHA.107.749234. Epub 2008 Feb 11.

PMID:
18268142

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