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Items: 16


Peripheral Blood TCR Repertoire Profiling May Facilitate Patient Stratification for Immunotherapy against Melanoma.

Hogan SA, Courtier A, Cheng PF, Jaberg-Bentele NF, Goldinger SM, Manuel M, Perez S, Plantier N, Mouret JF, Nguyen-Kim TDL, Raaijmakers MIG, Kvistborg P, Pasqual N, Haanen JBAG, Dummer R, Levesque MP.

Cancer Immunol Res. 2019 Jan;7(1):77-85. doi: 10.1158/2326-6066.CIR-18-0136. Epub 2018 Nov 13.


Peripheral T cell receptor diversity is associated with clinical outcomes following ipilimumab treatment in metastatic melanoma.

Postow MA, Manuel M, Wong P, Yuan J, Dong Z, Liu C, Perez S, Tanneau I, Noel M, Courtier A, Pasqual N, Wolchok JD.

J Immunother Cancer. 2015 Jun 16;3:23. doi: 10.1186/s40425-015-0070-4. eCollection 2015.


Clonal restriction and predominance of regulatory T cells in coronary thrombi of patients with acute coronary syndromes.

Klingenberg R, Brokopp CE, Grivès A, Courtier A, Jaguszewski M, Pasqual N, Vlaskou Badra E, Lewandowski A, Gaemperli O, Hoerstrup SP, Maier W, Landmesser U, Lüscher TF, Matter CM.

Eur Heart J. 2015 May 1;36(17):1041-8. doi: 10.1093/eurheartj/eht543. Epub 2014 Jan 12.


Patients with metastatic breast cancer leading to CD4+ T cell lymphopaenia have poor outcome.

Trédan O, Manuel M, Clapisson G, Bachelot T, Chabaud S, Bardin-dit-Courageot C, Rigal C, Biota C, Bajard A, Pasqual N, Blay JY, Caux C, Ménétrier-Caux C.

Eur J Cancer. 2013 May;49(7):1673-82. doi: 10.1016/j.ejca.2012.11.028. Epub 2012 Dec 19.


Decreased T-cell repertoire diversity in sepsis: a preliminary study.

Venet F, Filipe-Santos O, Lepape A, Malcus C, Poitevin-Later F, Grives A, Plantier N, Pasqual N, Monneret G.

Crit Care Med. 2013 Jan;41(1):111-9. doi: 10.1097/CCM.0b013e3182657948.


Lymphopenia combined with low TCR diversity (divpenia) predicts poor overall survival in metastatic breast cancer patients.

Manuel M, Tredan O, Bachelot T, Clapisson G, Courtier A, Parmentier G, Rabeony T, Grives A, Perez S, Mouret JF, Perol D, Chabaud S, Ray-Coquard I, Labidi-Galy I, Heudel P, Pierga JY, Caux C, Blay JY, Pasqual N, Ménétrier-Caux C.

Oncoimmunology. 2012 Jul 1;1(4):432-440.


Optimal epitope composition after antigen screening using a live bacterial delivery vector: application to TRP-2.

Derouazi M, Wang Y, Marlu R, Epaulard O, Mayol JF, Pasqual N, Le Gouellec A, Polack B, Toussaint B.

Bioeng Bugs. 2010 Jan-Feb;1(1):51-60. doi: 10.4161/bbug.1.1.9482.


Numerical modelling of the V-J combinations of the T cell receptor TRA/TRD locus.

Thuderoz F, Simonet MA, Hansen O, Pasqual N, Dariz A, Baum TP, Hierle V, Demongeot J, Marche PN, Jouvin-Marche E.

PLoS Comput Biol. 2010 Feb 19;6(2):e1000682. doi: 10.1371/journal.pcbi.1000682.


High diversity of the immune repertoire in humanized NOD.SCID.gamma c-/- mice.

Marodon G, Desjardins D, Mercey L, Baillou C, Parent P, Manuel M, Caux C, Bellier B, Pasqual N, Klatzmann D.

Eur J Immunol. 2009 Aug;39(8):2136-45. doi: 10.1002/eji.200939480.


Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

Gobert M, Treilleux I, Bendriss-Vermare N, Bachelot T, Goddard-Leon S, Arfi V, Biota C, Doffin AC, Durand I, Olive D, Perez S, Pasqual N, Faure C, Ray-Coquard I, Puisieux A, Caux C, Blay JY, Ménétrier-Caux C.

Cancer Res. 2009 Mar 1;69(5):2000-9. doi: 10.1158/0008-5472.CAN-08-2360. Epub 2009 Feb 24.


Analysis of the TCR alpha-chain rearrangement profile in human T lymphocytes.

Fuschiotti P, Pasqual N, Hierle V, Borel E, London J, Marche PN, Jouvin-Marche E.

Mol Immunol. 2007 Jul;44(13):3380-8. Epub 2007 Mar 27.


IMGT/GeneInfo: T cell receptor gamma TRG and delta TRD genes in database give access to all TR potential V(D)J recombinations.

Baum TP, Hierle V, Pasqual N, Bellahcene F, Chaume D, Lefranc MP, Jouvin-Marche E, Marche PN, Demongeot J.

BMC Bioinformatics. 2006 Apr 26;7:224.


Role of the T cell receptor alpha chain in the development and phenotype of naturally arising CD4+CD25+ T cells.

Bosco N, Hung HC, Pasqual N, Jouvin-Marche E, Marche PN, Gascoigne NR, Ceredig R.

Mol Immunol. 2006 Feb;43(3):246-54.


IMGT/GeneInfo: enhancing V(D)J recombination database accessibility.

Baum TP, Pasqual N, Thuderoz F, Hierle V, Chaume D, Lefranc MP, Jouvin-Marche E, Marche PN, Demongeot J.

Nucleic Acids Res. 2004 Jan 1;32(Database issue):D51-4.


Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoire.

Pasqual N, Gallagher M, Aude-Garcia C, Loiodice M, Thuderoz F, Demongeot J, Ceredig R, Marche PN, Jouvin-Marche E.

J Exp Med. 2002 Nov 4;196(9):1163-73.


Bcl-2/Bax protein expression in heart, slow-twitch and fast-twitch muscles in young rats growing under chronic hypoxia conditions.

Riva C, Chevrier C, Pasqual N, Saks V, Rossi A.

Mol Cell Biochem. 2001 Oct;226(1-2):9-16.


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