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Items: 24


Role of Intelligence Quotient (IQ) on anxiety and behavior in children with hearing and speech impairment.

Shetty RM, Pashine A, Jose NA, Mantha S.

Spec Care Dentist. 2018 Jan;38(1):13-18. doi: 10.1111/scd.12264. Epub 2018 Jan 4.


Hydrogen/deuterium exchange mass spectrometry and computational modeling reveal a discontinuous epitope of an antibody/TL1A Interaction.

Huang RY, Krystek SR Jr, Felix N, Graziano RF, Srinivasan M, Pashine A, Chen G.

MAbs. 2018 Jan;10(1):95-103. doi: 10.1080/19420862.2017.1393595. Epub 2017 Nov 14.


A robust high throughput platform to generate functional recombinant monoclonal antibodies using rabbit B cells from peripheral blood.

Seeber S, Ros F, Thorey I, Tiefenthaler G, Kaluza K, Lifke V, Fischer JA, Klostermann S, Endl J, Kopetzki E, Pashine A, Siewe B, Kaluza B, Platzer J, Offner S.

PLoS One. 2014 Feb 4;9(2):e86184. doi: 10.1371/journal.pone.0086184. eCollection 2014.


Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy.

Liao C, Hsu J, Kim Y, Hu DQ, Xu D, Zhang J, Pashine A, Menke J, Whittard T, Romero N, Truitt T, Slade M, Lukacs C, Hermann J, Zhou M, Lucas M, Narula S, DeMartino J, Tan SL.

Arthritis Res Ther. 2013 Oct 4;15(5):R146. doi: 10.1186/ar4329.


Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma.

Cheng DT, Ma C, Niewoehner J, Dahl M, Tsai A, Zhang J, Gonsiorek W, Apparsundaram S, Pashine A, Ravindran P, Jung J, Hang J, Allard J, Bitter H, Tribouley C, Narula S, Wilson S, Fuentes ME.

J Allergy Clin Immunol. 2013 Aug;132(2):455-62. doi: 10.1016/j.jaci.2013.05.011. Epub 2013 Jun 26.


RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.

Xu D, Kim Y, Postelnek J, Vu MD, Hu DQ, Liao C, Bradshaw M, Hsu J, Zhang J, Pashine A, Srinivasan D, Woods J, Levin A, O'Mahony A, Owens TD, Lou Y, Hill RJ, Narula S, DeMartino J, Fine JS.

J Pharmacol Exp Ther. 2012 Apr;341(1):90-103. doi: 10.1124/jpet.111.187740. Epub 2012 Jan 6.


Human cytomegalovirus decreases constitutive transcription of MHC class II genes in mature Langerhans cells by reducing CIITA transcript levels.

Lee AW, Wang N, Hornell TM, Harding JJ, Deshpande C, Hertel L, Lacaille V, Pashine A, Macaubas C, Mocarski ES, Mellins ED.

Mol Immunol. 2011 May;48(9-10):1160-7. doi: 10.1016/j.molimm.2011.02.010. Epub 2011 Mar 31.


DM influences the abundance of major histocompatibility complex class II alleles with low affinity for class II-associated invariant chain peptides via multiple mechanisms.

Rinderknecht CH, Roh S, Pashine A, Belmares MP, Patil NS, Lu N, Truong P, Hou T, Macaubas C, Yoon T, Wang N, Busch R, Mellins ED.

Immunology. 2010 Sep;131(1):18-32. doi: 10.1111/j.1365-2567.2010.03282.x. Epub 2010 Apr 12.


Failed efficacy of soluble human CD83-Ig in allogeneic mixed lymphocyte reactions and experimental autoimmune encephalomyelitis: implications for a lack of therapeutic potential.

Pashine A, Göpfert U, Chen J, Hoffmann E, Dietrich PS, Peng SL.

Immunol Lett. 2008 Jan 15;115(1):9-15. Epub 2007 Nov 29.


The candidate lupus susceptibility gene Ifi202a is largely dispensable for B-cell function.

Gubbels Bupp MR, Li M, Pashine A, Aud D, Peng SL.

Rheumatology (Oxford). 2008 Jan;47(1):103-4. Epub 2007 Nov 22. No abstract available.


NKp46 and NKG2D recognition of infected dendritic cells is necessary for NK cell activation in the human response to influenza infection.

Draghi M, Pashine A, Sanjanwala B, Gendzekhadze K, Cantoni C, Cosman D, Moretta A, Valiante NM, Parham P.

J Immunol. 2007 Mar 1;178(5):2688-98.


Human cytomegalovirus alters localization of MHC class II and dendrite morphology in mature Langerhans cells.

Lee AW, Hertel L, Louie RK, Burster T, Lacaille V, Pashine A, Abate DA, Mocarski ES, Mellins ED.

J Immunol. 2006 Sep 15;177(6):3960-71.


Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation.

Hornell TM, Burster T, Jahnsen FL, Pashine A, Ochoa MT, Harding JJ, Macaubas C, Lee AW, Modlin RL, Mellins ED.

J Immunol. 2006 Mar 15;176(6):3536-47.


Targeting the innate immune response with improved vaccine adjuvants.

Pashine A, Valiante NM, Ulmer JB.

Nat Med. 2005 Apr;11(4 Suppl):S63-8. Review.


Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides.

Pashine A, Busch R, Belmares MP, Munning JN, Doebele RC, Buckingham M, Nolan GP, Mellins ED.

Immunity. 2003 Aug;19(2):183-92.


Stabilization of soluble, low-affinity HLA-DM/HLA-DR1 complexes by leucine zippers.

Busch R, Pashine A, Garcia KC, Mellins ED.

J Immunol Methods. 2002 May 1;263(1-2):111-21.


Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles.

Patil NS, Pashine A, Belmares MP, Liu W, Kaneshiro B, Rabinowitz J, McConnell H, Mellins ED.

J Immunol. 2001 Dec 15;167(12):7157-68.


Determination of the HLA-DM interaction site on HLA-DR molecules.

Doebele RC, Busch R, Scott HM, Pashine A, Mellins ED.

Immunity. 2000 Oct;13(4):517-27.


Accessory molecules for MHC class II peptide loading.

Busch R, Doebele RC, Patil NS, Pashine A, Mellins ED.

Curr Opin Immunol. 2000 Feb;12(1):99-106. Review.


Th1 dominance in the immune response to live Salmonella typhimurium requires bacterial invasiveness but not persistence.

Pashine A, John B, Rath S, George A, Bal V.

Int Immunol. 1999 Apr;11(4):481-9.


Inhibition of T cell proliferation by macrophage tryptophan catabolism.

Munn DH, Shafizadeh E, Attwood JT, Bondarev I, Pashine A, Mellor AL.

J Exp Med. 1999 May 3;189(9):1363-72.

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