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Multimodal 18F-AV-1451 and MRI findings in non-fluent variant primary progressive aphasia: possible insights on nodal propagation of tau protein across the syntactic network.

Pascual B, Funk Q, Zanotti-Fregonara P, Pal N, Rockers E, Yu MM, Spann B, Román GC, Schulz PE, Karmonic C, Appel SH, Masdeu JC.

J Nucl Med. 2019 Jul 26. pii: jnumed.118.225508. doi: 10.2967/jnumed.118.225508. [Epub ahead of print]


Head-to-head comparison of 11C-PBR28 and 11C-ER176 for quantification of the translocator protein in the human brain.

Zanotti-Fregonara P, Pascual B, Veronese M, Yu M, Beers D, Appel SH, Masdeu JC.

Eur J Nucl Med Mol Imaging. 2019 Aug;46(9):1822-1829. doi: 10.1007/s00259-019-04349-w. Epub 2019 May 31.


The validity of 18F-GE180 as a TSPO imaging agent.

Zanotti-Fregonara P, Veronese M, Pascual B, Rostomily RC, Turkheimer F, Masdeu JC.

Eur J Nucl Med Mol Imaging. 2019 Jun;46(6):1205-1207. doi: 10.1007/s00259-019-4268-4. Epub 2019 Jan 17. No abstract available.


"Ears of the Lynx" MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia.

Pascual B, de Bot ST, Daniels MR, França MC Jr, Toro C, Riverol M, Hedera P, Bassi MT, Bresolin N, van de Warrenburg BP, Kremer B, Nicolai J, Charles P, Xu J, Singh S, Patronas NJ, Fung SH, Gregory MD, Masdeu JC.

AJNR Am J Neuroradiol. 2019 Jan;40(1):199-203. doi: 10.3174/ajnr.A5935. Epub 2019 Jan 3.


Proprioceptive Stabilizer™ training of the abdominal wall muscles in healthy subjects: a quasi-experimental study.

Morales CR, Sanz DR, Reguera MC, Martínez SF, González PT, Pascual BM.

Rev Assoc Med Bras (1992). 2018 Dec;64(12):1134-1138. doi: 10.1590/1806-9282.64.12.1134.


Sensory Polymeric Foams as a Tool for Improving Sensing Performance of Sensory Polymers.

Pascual BS, Vallejos S, Ramos C, Sanz MT, Reglero Ruiz JA, García FC, García JM.

Sensors (Basel). 2018 Dec 11;18(12). pii: E4378. doi: 10.3390/s18124378.


Functional alterations of myeloid cells during the course of Alzheimer's disease.

Thome AD, Faridar A, Beers DR, Thonhoff JR, Zhao W, Wen S, Pascual B, Masdeu JC, Appel SH.

Mol Neurodegener. 2018 Nov 13;13(1):61. doi: 10.1186/s13024-018-0293-1.


Conversion of L-dopa to Extended Release L-dopa (Rytary®) in Patients with Fluctuating Parkinson's Disease: Predictors of Dose.

Ondo W, Coss P, Christie M, Pascual B.

J Parkinsons Dis. 2019;9(1):153-156. doi: 10.3233/JPD-181427.


Easy and inexpensive method for the visual and electronic detection of oxidants in air by using vinylic films with embedded aniline.

Pascual BS, Vallejos S, Reglero Ruiz JA, Bertolín JC, Represa C, García FC, García JM.

J Hazard Mater. 2019 Feb 15;364:238-243. doi: 10.1016/j.jhazmat.2018.10.039. Epub 2018 Oct 22.


Hypothalamic relapse of a cardiac large B-cell lymphoma presenting with memory loss, confabulation, alexia-agraphia, apathy, hypersomnia, appetite disturbances and diabetes insipidus.

Ospina-García N, Román GC, Pascual B, Schwartz MR, Preti HA.

BMJ Case Rep. 2018 Aug 27;2018. pii: bcr-2016-217700. doi: 10.1136/bcr-2016-217700.


Head-to-Head Comparison of 11C-PBR28 and 18F-GE180 for Quantification of the Translocator Protein in the Human Brain.

Zanotti-Fregonara P, Pascual B, Rizzo G, Yu M, Pal N, Beers D, Carter R, Appel SH, Atassi N, Masdeu JC.

J Nucl Med. 2018 Aug;59(8):1260-1266. doi: 10.2967/jnumed.117.203109. Epub 2018 Jan 18.


A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies.

Liu SH, Gu Y, Pascual B, Yan Z, Hallin M, Zhang C, Fan C, Wang W, Lam J, Spilker ME, Yafawi R, Blasi E, Simmons B, Huser N, Ho WH, Lindquist K, Tran TT, Kudaravalli J, Ma JT, Jimenez G, Barman I, Brown C, Chin SM, Costa MJ, Shelton D, Smeal T, Fantin VR, Pernasetti F.

Blood Adv. 2017 Jun 21;1(15):1088-1100. doi: 10.1182/bloodadvances.2016003921. eCollection 2017 Jun 27.


Gemtuzumab Ozogamicin (GO) Inclusion to Induction Chemotherapy Eliminates Leukemic Initiating Cells and Significantly Improves Survival in Mouse Models of Acute Myeloid Leukemia.

Zhang CC, Yan Z, Pascual B, Jackson-Fisher A, Huang DS, Zong Q, Elliott M, Fan C, Huser N, Lee J, Sung M, Sapra P.

Neoplasia. 2018 Jan;20(1):1-11. doi: 10.1016/j.neo.2017.10.008. Epub 2017 Nov 21.


A Biomarker Combining Imaging and Neuropsychological Assessment for Tracking Early Alzheimer's Disease in Clinical Trials.

Verma N, Beretvas SN, Pascual B, Masdeu JC, Markey MK; Alzheimer's Disease Neuroimaging Initiative.

Curr Alzheimer Res. 2018 Mar 14;15(5):429-442. doi: 10.2174/1567205014666171106150309.


Monoclonal Antibody Protects Against Acinetobacter baumannii Infection by Enhancing Bacterial Clearance and Evading Sepsis.

Nielsen TB, Pantapalangkoor P, Luna BM, Bruhn KW, Yan J, Dekitani K, Hsieh S, Yeshoua B, Pascual B, Vinogradov E, Hujer KM, Domitrovic TN, Bonomo RA, Russo TA, Lesczcyniecka M, Schneider T, Spellberg B.

J Infect Dis. 2017 Aug 15;216(4):489-501. doi: 10.1093/infdis/jix315.


Generation of a human iPSC line from a patient with retinitis pigmentosa caused by mutation in PRPF8 gene.

Lukovic D, Bolinches-Amorós A, Artero-Castro A, Pascual B, Carballo M, Hernan I, Erceg S.

Stem Cell Res. 2017 May;21:23-25. doi: 10.1016/j.scr.2017.03.007. Epub 2017 Mar 15.


Clinical considerations and surgical approaches for low-grade gliomas in deep hemispheric locations: insular lesions.

Hinojosa J, Gil-Robles S, Pascual B.

Childs Nerv Syst. 2016 Oct;32(10):1875-93. doi: 10.1007/s00381-016-3183-2. Epub 2016 Sep 20. Review.


Genetic and degenerative disorders primarily causing dementia.

Masdeu JC, Pascual B.

Handb Clin Neurol. 2016;135:525-564. doi: 10.1016/B978-0-444-53485-9.00026-X. Review.


Tau, amyloid, and hypometabolism in the logopenic variant of primary progressive aphasia.

Pascual B, Masdeu JC.

Neurology. 2016 Feb 2;86(5):487-8. doi: 10.1212/WNL.0000000000002340. No abstract available.


[Rare location of arachnoid cysts. Extratemporal cysts].

Martinez-Perez R, Hinojosa J, Pascual B, Panaderos T, Welter D, Muñoz MJ.

Neurocirugia (Astur). 2016 May-Jun;27(3):121-8. doi: 10.1016/j.neucir.2015.10.004. Epub 2015 Dec 25. Review. Spanish.


New scoring methodology improves the sensitivity of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) in clinical trials.

Verma N, Beretvas SN, Pascual B, Masdeu JC, Markey MK; Alzheimer’s Disease Neuroimaging Initiative.

Alzheimers Res Ther. 2015 Nov 12;7(1):64. doi: 10.1186/s13195-015-0151-0.


New COL6A6 variant detected by whole-exome sequencing is linked to break points in intron 4 and 3'-UTR, deleting exon 5 of RHO, and causing adRP.

de Sousa Dias M, Hernan I, Delás B, Pascual B, Borràs E, Gamundi MJ, Mañé B, Fernández-San José P, Ayuso C, Carballo M.

Mol Vis. 2015 Aug 18;21:857-70. eCollection 2015.


Preclinical PK/PD modeling and human efficacious dose projection for a glucokinase activator in the treatment of diabetes.

Zager MG, Kozminski K, Pascual B, Ogilvie KM, Sun S.

J Pharmacokinet Pharmacodyn. 2014 Apr;41(2):127-39. doi: 10.1007/s10928-014-9351-7. Epub 2014 Feb 28.


Comparison of dynamic contrast-enhanced MR, ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of PF-03084014 and sunitinib.

Zhang CC, Yan Z, Giddabasappa A, Lappin PB, Painter CL, Zhang Q, Li G, Goodman J, Simmons B, Pascual B, Lee J, Levkoff T, Nichols T, Xie Z.

Cancer Med. 2014 Jun;3(3):462-71. doi: 10.1002/cam4.215. Epub 2014 Feb 27.


Large-scale brain networks of the human left temporal pole: a functional connectivity MRI study.

Pascual B, Masdeu JC, Hollenbeck M, Makris N, Insausti R, Ding SL, Dickerson BC.

Cereb Cortex. 2015 Mar;25(3):680-702. doi: 10.1093/cercor/bht260. Epub 2013 Sep 24.


Detection of novel mutations that cause autosomal dominant retinitis pigmentosa in candidate genes by long-range PCR amplification and next-generation sequencing.

de Sousa Dias M, Hernan I, Pascual B, Borràs E, Mañé B, Gamundi MJ, Carballo M.

Mol Vis. 2013;19:654-64. Epub 2013 Mar 21.


Detection of novel genetic variation in autosomal dominant retinitis pigmentosa.

Borràs E, de Sousa Dias M, Hernan I, Pascual B, Mañé B, Gamundi MJ, Delás B, Carballo M.

Clin Genet. 2013 Nov;84(5):441-52. doi: 10.1111/cge.12151. Epub 2013 Apr 15.


Contribution of neuroimaging to the diagnosis of Alzheimer's disease and vascular dementia.

Román G, Pascual B.

Arch Med Res. 2012 Nov;43(8):671-6. doi: 10.1016/j.arcmed.2012.10.018. Epub 2012 Nov 8. Review.


Decreased carbon-11-flumazenil binding in early Alzheimer's disease.

Pascual B, Prieto E, Arbizu J, Marti-Climent JM, Peñuelas I, Quincoces G, Zarauza R, Pappatà S, Masdeu JC.

Brain. 2012 Sep;135(Pt 9):2817-25. doi: 10.1093/brain/aws210.


Bounded phase phenomena in the optically injected laser.

Kelleher B, Goulding D, Pascual BB, Hegarty SP, Huyet G.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Apr;85(4 Pt 2):046212. Epub 2012 Apr 18.


Effective targeting of Hedgehog signaling in a medulloblastoma model with PF-5274857, a potent and selective Smoothened antagonist that penetrates the blood-brain barrier.

Rohner A, Spilker ME, Lam JL, Pascual B, Bartkowski D, Li QJ, Yang AH, Stevens G, Xu M, Wells PA, Planken S, Nair S, Sun S.

Mol Cancer Ther. 2012 Jan;11(1):57-65. doi: 10.1158/1535-7163.MCT-11-0691. Epub 2011 Nov 14.


Age-related changes in the thickness of cortical zones in humans.

McGinnis SM, Brickhouse M, Pascual B, Dickerson BC.

Brain Topogr. 2011 Oct;24(3-4):279-91. doi: 10.1007/s10548-011-0198-6. Epub 2011 Aug 14.


Evaluation of a microbiological screening and acceptance procedure for cryopreserved skin allografts based on 14 day cultures.

Pirnay JP, Verween G, Pascual B, Verbeken G, De Corte P, Rose T, Jennes S, Vanderkelen A, Marichal M, Heuninckx W, De Vos D.

Cell Tissue Bank. 2012 Jun;13(2):287-95. doi: 10.1007/s10561-011-9256-2. Epub 2011 Apr 21.


Glycerol treatment as recovery procedure for cryopreserved human skin allografts positive for bacteria and fungi.

Verbeken G, Verween G, De Vos D, Pascual B, De Corte P, Richters C, De Coninck A, Roseeuw D, Ectors N, Rose T, Jennes S, Pirnay JP.

Cell Tissue Bank. 2012 Mar;13(1):1-7. doi: 10.1007/s10561-011-9244-6. Epub 2011 Mar 1.


Brain glucose metabolism in vascular white matter disease with dementia: differentiation from Alzheimer disease.

Pascual B, Prieto E, Arbizu J, Marti-Climent J, Olier J, Masdeu JC.

Stroke. 2010 Dec;41(12):2889-93. doi: 10.1161/STROKEAHA.110.591552. Epub 2010 Nov 4.


4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.

Liu KK, Bagrodia S, Bailey S, Cheng H, Chen H, Gao L, Greasley S, Hoffman JE, Hu Q, Johnson TO, Knighton D, Liu Z, Marx MA, Nambu MD, Ninkovic S, Pascual B, Rafidi K, Rodgers CM, Smith GL, Sun S, Wang H, Yang A, Yuan J, Zou A.

Bioorg Med Chem Lett. 2010 Oct 15;20(20):6096-9. doi: 10.1016/j.bmcl.2010.08.045. Epub 2010 Aug 14.


New mutation in female patient with renal variant of Fabry disease and HIV.

Solis MA, Pascual B, Boscá M, Ramos V, Carda C, Monteagudo C, Torregrosa I, Pons S, Miguel A.

J Nephrol. 2010 Mar-Apr;23(2):231-3.


Potential release of aluminum and other metals by food-grade aluminum foil used for skin allograft cryo preservation.

Verbeken G, Schoeters D, Verween G, De Vos D, Pascual B, De Corte P, Geukens K, De Coninck A, Roseeuw D, Rose T, Jennes S, Pirnay JP.

Cell Tissue Bank. 2011 Aug;12(3):241-6. doi: 10.1007/s10561-010-9171-y. Epub 2010 Feb 10.


[Evolution of kidney function and progression factors in nephrectomised patients].

Juan I, Puchades MJ, Solís MA, Pascual B, Torregrosa I, Ramos C, González M, Miguel A.

Nefrologia. 2010;30(2):202-7. doi: 10.3265/Nefrologia.pre2010.Jan.10230. Epub 2010 Jan 21. Spanish.


Ventricular wall granulations and draining of cerebrospinal fluid in chronic giant hydrocephalus.

Masdeu JC, Pascual B, Bressi F, Casale M, Prieto E, Arbizu J, Fernández-Seara MA.

Arch Neurol. 2009 Feb;66(2):262-7. doi: 10.1001/archneurol.2008.547.


Surgical treatment of isolated and syndromic craniosynostosis. Results and complications in 283 consecutive cases.

Esparza J, Hinojosa J, García-Recuero I, Romance A, Pascual B, Martínez de Aragón A.

Neurocirugia (Astur). 2008 Dec;19(6):509-29.


Forceps minor region signal abnormality "ears of the lynx": an early MRI finding in spastic paraparesis with thin corpus callosum and mutations in the spatacsin gene (SPG11) on chromosome 15.

Riverol M, Samaranch L, Pascual B, Pastor P, Irigoyen J, Pastor MA, de Castro P, Masdeu JC.

J Neuroimaging. 2009 Jan;19(1):52-60. doi: 10.1111/j.1552-6569.2008.00327.x. Epub 2008 Nov 21.


Neuroimaging of disorders leading to dementia.

Masdeu JC, Pascual B.

Curr Neurol Neurosci Rep. 2008 Nov;8(6):443-4. No abstract available.


[Embolization of indirect carotid-cavernous sinus fistula through the ophthalmic vein].

Alén JF, Campollo J, Rivas JJ, Lagares A, Pascual B, Jiménez-Roldán L, Lobato RD.

Neurocirugia (Astur). 2008 Aug;19(4):338-42. Spanish.


[Thrombocytopenia in a patient on peritoneal dialysis].

Pascual BO, Solis MA, Ramos VB, Juan IG, Torregrosa IM, García RR, Carrasco AM.

Nefrologia. 2008;28(4):453-5. Spanish.


Acquisition of mental state language in Spanish children: a longitudinal study of the relationship between the production of mental verbs and linguistic development.

Pascual B, Aguado G, Sotillo M, Masdeu JC.

Dev Sci. 2008 Jul;11(4):454-66. doi: 10.1111/j.1467-7687.2008.00691.x.


[Olfactory alterations in allergic rhinitis to pollens and mites].

de Haro J, Benítez P, Alobid I, González JA, Pascual B, Mullol J.

Acta Otorrinolaringol Esp. 2008 Feb;59(2):47-51. Spanish.


[Surgical treatment for spontaneous intracerebral haemorrhage. Part I: supratentorial haematomas].

Pérez-Nuñez A, Lagares A, Pascual B, Rivas JJ, Alday R, González P, Cabrera A, Lobato RD.

Neurocirugia (Astur). 2008 Feb;19(1):12-24. Review. Spanish.


Antisense inhibition of 11betahydroxysteroid dehydrogenase type 1 improves diabetes in a novel cortisone-induced diabetic KK mouse model.

Bhat BG, Younis H, Herrera J, Palacio K, Pascual B, Hur G, Jessen B, Ogilvie KM, Rejto PA.

Biochem Biophys Res Commun. 2008 Jan 25;365(4):740-5. Epub 2007 Nov 20.


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