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Items: 33


SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons.

Zaslavsky K, Zhang WB, McCready FP, Rodrigues DC, Deneault E, Loo C, Zhao M, Ross PJ, El Hajjar J, Romm A, Thompson T, Piekna A, Wei W, Wang Z, Khattak S, Mufteev M, Pasceri P, Scherer SW, Salter MW, Ellis J.

Nat Neurosci. 2019 Apr;22(4):556-564. doi: 10.1038/s41593-019-0365-8. Epub 2019 Mar 25.


Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons.

Deneault E, White SH, Rodrigues DC, Ross PJ, Faheem M, Zaslavsky K, Wang Z, Alexandrova R, Pellecchia G, Wei W, Piekna A, Kaur G, Howe JL, Kwan V, Thiruvahindrapuram B, Walker S, Lionel AC, Pasceri P, Merico D, Yuen RKC, Singh KK, Ellis J, Scherer SW.

Stem Cell Reports. 2019 Feb 12;12(2):427-429. doi: 10.1016/j.stemcr.2019.01.008. No abstract available.


CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks.

Deneault E, Faheem M, White SH, Rodrigues DC, Sun S, Wei W, Piekna A, Thompson T, Howe JL, Chalil L, Kwan V, Walker S, Pasceri P, Roth FP, Yuen RK, Singh KK, Ellis J, Scherer SW.

Elife. 2019 Feb 12;8. pii: e40092. doi: 10.7554/eLife.40092.


Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons.

Deneault E, White SH, Rodrigues DC, Ross PJ, Faheem M, Zaslavsky K, Wang Z, Alexandrova R, Pellecchia G, Wei W, Piekna A, Kaur G, Howe JL, Kwan V, Thiruvahindrapuram B, Walker S, Lionel AC, Pasceri P, Merico D, Yuen RKC, Singh KK, Ellis J, Scherer SW.

Stem Cell Reports. 2018 Nov 13;11(5):1211-1225. doi: 10.1016/j.stemcr.2018.10.003. Epub 2018 Nov 1. Erratum in: Stem Cell Reports. 2019 Feb 12;12(2):427-429.


The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants.

Reuter MS, Walker S, Thiruvahindrapuram B, Whitney J, Cohn I, Sondheimer N, Yuen RKC, Trost B, Paton TA, Pereira SL, Herbrick JA, Wintle RF, Merico D, Howe J, MacDonald JR, Lu C, Nalpathamkalam T, Sung WWL, Wang Z, Patel RV, Pellecchia G, Wei J, Strug LJ, Bell S, Kellam B, Mahtani MM, Bassett AS, Bombard Y, Weksberg R, Shuman C, Cohn RD, Stavropoulos DJ, Bowdin S, Hildebrandt MR, Wei W, Romm A, Pasceri P, Ellis J, Ray P, Meyn MS, Monfared N, Hosseini SM, Joseph-George AM, Keeley FW, Cook RA, Fiume M, Lee HC, Marshall CR, Davies J, Hazell A, Buchanan JA, Szego MJ, Scherer SW.

CMAJ. 2018 Feb 5;190(5):E126-E136. doi: 10.1503/cmaj.171151.


MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells.

Djuric U, Cheung AYL, Zhang W, Mok RS, Lai W, Piekna A, Hendry JA, Ross PJ, Pasceri P, Kim DS, Salter MW, Ellis J.

Neurobiol Dis. 2015 Apr;76:37-45. doi: 10.1016/j.nbd.2015.01.001. Epub 2015 Jan 30.


Kinetics and epigenetics of retroviral silencing in mouse embryonic stem cells defined by deletion of the D4Z4 element.

Rival-Gervier S, Lo MY, Khattak S, Pasceri P, Lorincz MC, Ellis J.

Mol Ther. 2013 Aug;21(8):1536-50. doi: 10.1038/mt.2013.131. Epub 2013 Jun 11.


Modeling and rescue of the vascular phenotype of Williams-Beuren syndrome in patient induced pluripotent stem cells.

Kinnear C, Chang WY, Khattak S, Hinek A, Thompson T, de Carvalho Rodrigues D, Kennedy K, Mahmut N, Pasceri P, Stanford WL, Ellis J, Mital S.

Stem Cells Transl Med. 2013 Jan;2(1):2-15. doi: 10.5966/sctm.2012-0054. Epub 2012 Dec 21.


Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein.

Wong AP, Bear CE, Chin S, Pasceri P, Thompson TO, Huan LJ, Ratjen F, Ellis J, Rossant J.

Nat Biotechnol. 2012 Sep;30(9):876-82.


Rapid transcriptional pulsing dynamics of high expressing retroviral transgenes in embryonic stem cells.

Lo MY, Rival-Gervier S, Pasceri P, Ellis J.

PLoS One. 2012;7(5):e37130. doi: 10.1371/journal.pone.0037130. Epub 2012 May 14.


Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations.

Farra N, Zhang WB, Pasceri P, Eubanks JH, Salter MW, Ellis J.

Mol Psychiatry. 2012 Dec;17(12):1261-71. doi: 10.1038/mp.2011.180. Epub 2012 Jan 10.


Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation.

Cheung AY, Horvath LM, Grafodatskaya D, Pasceri P, Weksberg R, Hotta A, Carrel L, Ellis J.

Hum Mol Genet. 2011 Jun 1;20(11):2103-15. doi: 10.1093/hmg/ddr093. Epub 2011 Mar 3.


EOS lentiviral vector selection system for human induced pluripotent stem cells.

Hotta A, Cheung AY, Farra N, Garcha K, Chang WY, Pasceri P, Stanford WL, Ellis J.

Nat Protoc. 2009;4(12):1828-44. doi: 10.1038/nprot.2009.201.


MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy.

Rastegar M, Hotta A, Pasceri P, Makarem M, Cheung AY, Elliott S, Park KJ, Adachi M, Jones FS, Clarke ID, Dirks P, Ellis J.

PLoS One. 2009 Aug 27;4(8):e6810. doi: 10.1371/journal.pone.0006810.


Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency.

Hotta A, Cheung AY, Farra N, Vijayaragavan K, Séguin CA, Draper JS, Pasceri P, Maksakova IA, Mager DL, Rossant J, Bhatia M, Ellis J.

Nat Methods. 2009 May;6(5):370-6. doi: 10.1038/nmeth.1325. Epub 2009 Apr 26.


Beta-globin LCR and intron elements cooperate and direct spatial reorganization for gene therapy.

Buzina A, Lo MY, Moffett A, Hotta A, Fussner E, Bharadwaj RR, Pasceri P, Garcia-Martinez JV, Bazett-Jones DP, Ellis J.

PLoS Genet. 2008 Apr 11;4(4):e1000051. doi: 10.1371/journal.pgen.1000051.


eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides.

Dalle B, Rubin JE, Alkan O, Sukonnik T, Pasceri P, Yao S, Pawliuk R, Leboulch P, Ellis J.

Mol Ther. 2005 Apr;11(4):591-9.


Retrovirus silencer blocking by the cHS4 insulator is CTCF independent.

Yao S, Osborne CS, Bharadwaj RR, Pasceri P, Sukonnik T, Pannell D, Recillas-Targa F, West AG, Ellis J.

Nucleic Acids Res. 2003 Sep 15;31(18):5317-23.


Deviation of islet autoreactivity to cryptic epitopes protects NOD mice from diabetes.

Song A, Winer S, Tsui H, Sampson A, Pasceri P, Ellis J, Elliott JF, Dosch HM.

Eur J Immunol. 2003 Feb;33(2):546-55.


LCR-regulated transgene expression levels depend on the Oct-1 site in the AT-rich region of beta -globin intron-2.

Bharadwaj RR, Trainor CD, Pasceri P, Ellis J.

Blood. 2003 Feb 15;101(4):1603-10. Epub 2002 Sep 26.


Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code.

Pannell D, Osborne CS, Yao S, Sukonnik T, Pasceri P, Karaiskakis A, Okano M, Li E, Lipshitz HD, Ellis J.

EMBO J. 2000 Nov 1;19(21):5884-94.


Amelioration of retroviral vector silencing in locus control region beta-globin-transgenic mice and transduced F9 embryonic cells.

Osborne CS, Pasceri P, Singal R, Sukonnik T, Ginder GD, Ellis J.

J Virol. 1999 Jul;73(7):5490-6.


5'HS1 and the distal beta-globin promoter functionally interact in single copy beta-globin transgenic mice.

Pasceri P, Pannell D, Wu X, Ellis J.

Ann N Y Acad Sci. 1998 Jun 30;850:377-81. No abstract available.


Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.

Ellis J, Pasceri P, Tan-Un KC, Wu X, Harper A, Fraser P, Grosveld F.

Nucleic Acids Res. 1997 Mar 15;25(6):1296-302.


Postaxial polydactyly in forelimbs of CRABP-II mutant mice.

Fawcett D, Pasceri P, Fraser R, Colbert M, Rossant J, Giguère V.

Development. 1995 Mar;121(3):671-9.


Case studies: considering dressing options.

Brown-Etris M, Smith JA, Pasceri P, Punchello M.

Ostomy Wound Manage. 1994 Jun;40(5):46-8, 50-2. No abstract available.


Utilizing a prevention and treatment protocol for skin breakdown secondary to urinary incontinence.

Pasceri P.

Ostomy Wound Manage. 1991 Sep-Oct;36:66-9. No abstract available.


A new generation of gauze dressings.

Etris MB, Myers RB, Pasceri P.

Ostomy Wound Manage. 1991 May-Jun;34:57-9. No abstract available.


Two UV-sensitive targets in dorsoanterior specification of frog embryos.

Elinson RP, Pasceri P.

Development. 1989 Jul;106(3):511-8.

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