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Items: 17


Breaking the oncostatin M feed-forward loop to suppress metastasis and therapy failure.

Smigiel J, Parvani JG, Tamagno I, Polak K, Jackson MW.

J Pathol. 2018 May;245(1):6-8. doi: 10.1002/path.5063. Epub 2018 Apr 2.


Magnetic resonance molecular imaging of metastatic breast cancer by targeting extradomain-B fibronectin in the tumor microenvironment.

Han Z, Cheng H, Parvani JG, Zhou Z, Lu ZR.

Magn Reson Med. 2018 Jun;79(6):3135-3143. doi: 10.1002/mrm.26976. Epub 2017 Oct 29.


Silencing the roadblocks to effective triple-negative breast cancer treatments by siRNA nanoparticles.

Parvani JG, Jackson MW.

Endocr Relat Cancer. 2017 Apr;24(4):R81-R97. doi: 10.1530/ERC-16-0482. Epub 2017 Feb 1. Review.


Neoadjuvant therapy for early-stage breast cancer: the clinical utility of pertuzumab.

Gollamudi J, Parvani JG, Schiemann WP, Vinayak S.

Cancer Manag Res. 2016 Feb 18;8:21-31. doi: 10.2147/CMAR.S55279. eCollection 2016. Review.


Silencing β3 Integrin by Targeted ECO/siRNA Nanoparticles Inhibits EMT and Metastasis of Triple-Negative Breast Cancer.

Parvani JG, Gujrati MD, Mack MA, Schiemann WP, Lu ZR.

Cancer Res. 2015 Jun 1;75(11):2316-2325. doi: 10.1158/0008-5472.CAN-14-3485. Epub 2015 Apr 9.


Deptor enhances triple-negative breast cancer metastasis and chemoresistance through coupling to survivin expression.

Parvani JG, Davuluri G, Wendt MK, Espinosa C, Tian M, Danielpour D, Sossey-Alaoui K, Schiemann WP.

Neoplasia. 2015 Mar;17(3):317-28. doi: 10.1016/j.neo.2015.02.003.


Upregulated WAVE3 expression is essential for TGF-β-mediated EMT and metastasis of triple-negative breast cancer cells.

Taylor MA, Davuluri G, Parvani JG, Schiemann BJ, Wendt MK, Plow EF, Schiemann WP, Sossey-Alaoui K.

Breast Cancer Res Treat. 2013 Nov;142(2):341-53. doi: 10.1007/s10549-013-2753-1. Epub 2013 Nov 7.


Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β.

Parvani JG, Galliher-Beckley AJ, Schiemann BJ, Schiemann WP.

Mol Biol Cell. 2013 Nov;24(21):3449-59. doi: 10.1091/mbc.E12-10-0776. Epub 2013 Sep 4. Erratum in: Mol Biol Cell. 2014 Feb;25(4):548.


The relevance of the TGF-β Paradox to EMT-MET programs.

Morrison CD, Parvani JG, Schiemann WP.

Cancer Lett. 2013 Nov 28;341(1):30-40. doi: 10.1016/j.canlet.2013.02.048. Epub 2013 Mar 5. Review.


TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer.

Wendt MK, Schiemann BJ, Parvani JG, Lee YH, Kang Y, Schiemann WP.

Oncogene. 2013 Apr 18;32(16):2005-15. doi: 10.1038/onc.2012.230. Epub 2012 Jun 18.


Noncanonical TGF-β signaling during mammary tumorigenesis.

Parvani JG, Taylor MA, Schiemann WP.

J Mammary Gland Biol Neoplasia. 2011 Jun;16(2):127-46. doi: 10.1007/s10911-011-9207-3. Epub 2011 Mar 31. Review.


The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells.

Taylor MA, Parvani JG, Schiemann WP.

J Mammary Gland Biol Neoplasia. 2010 Jun;15(2):169-90. doi: 10.1007/s10911-010-9181-1. Epub 2010 May 15. Review.


An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance.

Mitra D, Brumlik MJ, Okamgba SU, Zhu Y, Duplessis TT, Parvani JG, Lesko SM, Brogi E, Jones FE.

Mol Cancer Ther. 2009 Aug;8(8):2152-62. doi: 10.1158/1535-7163.MCT-09-0295. Epub 2009 Aug 11.


IL-21 induces apoptosis of antigen-specific CD8+ T lymphocytes.

Barker BR, Parvani JG, Meyer D, Hey AS, Skak K, Letvin NL.

J Immunol. 2007 Sep 15;179(6):3596-603.


No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys.

Letvin NL, Rao SS, Dang V, Buzby AP, Korioth-Schmitz B, Dombagoda D, Parvani JG, Clarke RH, Bar L, Carlson KR, Kozlowski PA, Hirsch VM, Mascola JR, Nabel GJ.

J Virol. 2007 Nov;81(22):12368-74. Epub 2007 Aug 8.


Heterologous prime/boost immunization of rhesus monkeys by using diverse poxvirus vectors.

Santra S, Sun Y, Parvani JG, Philippon V, Wyand MS, Manson K, Gomez-Yafal A, Mazzara G, Panicali D, Markham PD, Montefiori DC, Letvin NL.

J Virol. 2007 Aug;81(16):8563-70. Epub 2007 Jun 6.

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