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Items: 1 to 50 of 124

1.

Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B.

Hogarth MW, Defour A, Lazarski C, Gallardo E, Diaz Manera J, Partridge TA, Nagaraju K, Jaiswal JK.

Nat Commun. 2019 Jun 3;10(1):2430. doi: 10.1038/s41467-019-10438-z.

PMID:
31160583
2.

Application of Magnetic Resonance to Assess Lyophilized Drug Product Reconstitution.

Partridge TA, Ahmed M, Choudhary SB, van der Walle CF, Patel SM, Bishop SM, Mantle MD.

Pharm Res. 2019 Mar 22;36(5):71. doi: 10.1007/s11095-019-2591-x.

3.

Morpholino-induced exon skipping stimulates cell-mediated and humoral responses to dystrophin in mdx mice.

Vila MC, Novak JS, Benny Klimek M, Li N, Morales M, Fritz AG, Edwards K, Boehler JF, Hogarth MW, Kinder TB, Zhang A, Mazala D, Fiorillo AA, Douglas B, Chen YW, van den Anker J, Lu QL, Hathout Y, Hoffman EP, Partridge TA, Nagaraju K.

J Pathol. 2019 Jul;248(3):339-351. doi: 10.1002/path.5263. Epub 2019 Apr 16.

PMID:
30883742
4.

Shorter Phosphorodiamidate Morpholino Splice-Switching Oligonucleotides May Increase Exon-Skipping Efficacy in DMD.

Akpulat U, Wang H, Becker K, Contreras A, Partridge TA, Novak JS, Cirak S.

Mol Ther Nucleic Acids. 2018 Dec 7;13:534-542. doi: 10.1016/j.omtn.2018.10.002. Epub 2018 Oct 10.

5.

Direct solid state NMR observation of the 105Pd nucleus in inorganic compounds and palladium metal systems.

Hooper TJN, Partridge TA, Rees GJ, Keeble DS, Powell NA, Smith ME, Mikheenko IP, Macaskie LE, Bishop PT, Hanna JV.

Phys Chem Chem Phys. 2018 Nov 7;20(41):26734-26743. doi: 10.1039/c8cp02594k. Epub 2018 Oct 16.

PMID:
30324213
6.

The macrophage as a Trojan horse for antisense oligonucleotide delivery.

Novak JS, Jaiswal JK, Partridge TA.

Expert Opin Ther Targets. 2018 Jun;22(6):463-466. doi: 10.1080/14728222.2018.1482279. Epub 2018 Jun 7. No abstract available.

7.

Author Correction: Myoblasts and macrophages are required for therapeutic morpholino antisense oligonucleotide delivery to dystrophic muscle.

Novak JS, Hogarth MW, Boehler JF, Nearing M, Vila MC, Heredia R, Fiorillo AA, Zhang A, Hathout Y, Hoffman EP, Jaiswal JK, Nagaraju K, Cirak S, Partridge TA.

Nat Commun. 2018 Mar 23;9(1):1256. doi: 10.1038/s41467-018-03709-8.

8.

Author Correction: Myoblasts and macrophages are required for therapeutic morpholino antisense oligonucleotide delivery to dystrophic muscle.

Novak JS, Hogarth MW, Boehler JF, Nearing M, Vila MC, Heredia R, Fiorillo AA, Zhang A, Hathout Y, Hoffman EP, Jaiswal JK, Nagaraju K, Cirak S, Partridge TA.

Nat Commun. 2018 Jan 15;9(1):208. doi: 10.1038/s41467-017-02206-8.

9.

Myoblasts and macrophages are required for therapeutic morpholino antisense oligonucleotide delivery to dystrophic muscle.

Novak JS, Hogarth MW, Boehler JF, Nearing M, Vila MC, Heredia R, Fiorillo AA, Zhang A, Hathout Y, Hoffman EP, Jaiswal JK, Nagaraju K, Cirak S, Partridge TA.

Nat Commun. 2017 Oct 16;8(1):941. doi: 10.1038/s41467-017-00924-7. Erratum in: Nat Commun. 2018 Jan 15;9(1):208. Nat Commun. 2018 Mar 23;9(1):1256.

10.

Elusive sources of variability of dystrophin rescue by exon skipping.

Vila MC, Klimek MB, Novak JS, Rayavarapu S, Uaesoontrachoon K, Boehler JF, Fiorillo AA, Hogarth MW, Zhang A, Shaughnessy C, Gordish-Dressman H, Burki U, Straub V, Lu QL, Partridge TA, Brown KJ, Hathout Y, van den Anker J, Hoffman EP, Nagaraju K.

Skelet Muscle. 2015 Dec 1;5:44. doi: 10.1186/s13395-015-0070-6. eCollection 2015.

11.

Effect of genetic background on the dystrophic phenotype in mdx mice.

Coley WD, Bogdanik L, Vila MC, Yu Q, Van Der Meulen JH, Rayavarapu S, Novak JS, Nearing M, Quinn JL, Saunders A, Dolan C, Andrews W, Lammert C, Austin A, Partridge TA, Cox GA, Lutz C, Nagaraju K.

Hum Mol Genet. 2016 Jan 1;25(1):130-45. doi: 10.1093/hmg/ddv460. Epub 2015 Nov 12.

12.

TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy.

Fiorillo AA, Heier CR, Novak JS, Tully CB, Brown KJ, Uaesoontrachoon K, Vila MC, Ngheim PP, Bello L, Kornegay JN, Angelini C, Partridge TA, Nagaraju K, Hoffman EP.

Cell Rep. 2015 Sep 8;12(10):1678-90. doi: 10.1016/j.celrep.2015.07.066. Epub 2015 Aug 28.

13.

Upregulated IL-1β in dysferlin-deficient muscle attenuates regeneration by blunting the response to pro-inflammatory macrophages.

Cohen TV, Many GM, Fleming BD, Gnocchi VF, Ghimbovschi S, Mosser DM, Hoffman EP, Partridge TA.

Skelet Muscle. 2015 Aug 7;5:24. doi: 10.1186/s13395-015-0048-4. eCollection 2015.

14.

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

Hettmer S, Li Z, Billin AN, Barr FG, Cornelison DD, Ehrlich AR, Guttridge DC, Hayes-Jordan A, Helman LJ, Houghton PJ, Khan J, Langenau DM, Linardic CM, Pal R, Partridge TA, Pavlath GK, Rota R, Schäfer BW, Shipley J, Stillman B, Wexler LH, Wagers AJ, Keller C.

Cold Spring Harb Perspect Med. 2014 Nov 3;4(11):a025650. doi: 10.1101/cshperspect.a025650. Review.

15.

Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.

Dadgar S, Wang Z, Johnston H, Kesari A, Nagaraju K, Chen YW, Hill DA, Partridge TA, Giri M, Freishtat RJ, Nazarian J, Xuan J, Wang Y, Hoffman EP.

J Cell Biol. 2014 Oct 13;207(1):139-58. doi: 10.1083/jcb.201402079.

16.

Multiple insights from myogenic cell transplants.

Partridge TA, Morgan JE.

Hum Gene Ther. 2014 May;25(5):404-5. doi: 10.1089/hum.2014.035. No abstract available.

PMID:
24848316
17.

Survival motor neuron protein deficiency impairs myotube formation by altering myogenic gene expression and focal adhesion dynamics.

Bricceno KV, Martinez T, Leikina E, Duguez S, Partridge TA, Chernomordik LV, Fischbeck KH, Sumner CJ, Burnett BG.

Hum Mol Genet. 2014 Sep 15;23(18):4745-57. doi: 10.1093/hmg/ddu189. Epub 2014 Apr 23.

18.

Human skeletal muscle xenograft as a new preclinical model for muscle disorders.

Zhang Y, King OD, Rahimov F, Jones TI, Ward CW, Kerr JP, Liu N, Emerson CP Jr, Kunkel LM, Partridge TA, Wagner KR.

Hum Mol Genet. 2014 Jun 15;23(12):3180-8. doi: 10.1093/hmg/ddu028. Epub 2014 Jan 22.

19.

The mdx mouse model as a surrogate for Duchenne muscular dystrophy.

Partridge TA.

FEBS J. 2013 Sep;280(17):4177-86. doi: 10.1111/febs.12267. Epub 2013 Apr 22. Review.

20.

Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α.

Cohen TV, Gnocchi VF, Cohen JE, Phadke A, Liu H, Ellis JA, Foisner R, Stewart CL, Zammit PS, Partridge TA.

Hum Mol Genet. 2013 Jul 15;22(14):2852-69. doi: 10.1093/hmg/ddt135. Epub 2013 Mar 27.

21.

The satellite cell builds its nest under Notch's guidance.

Lepper C, Low S, Partridge TA.

Cell Stem Cell. 2012 Oct 5;11(4):443-4. doi: 10.1016/j.stem.2012.09.010.

22.

Atmospheric oxygen tension slows myoblast proliferation via mitochondrial activation.

Duguez S, Duddy WJ, Gnocchi V, Bowe J, Dadgar S, Partridge TA.

PLoS One. 2012;7(8):e43853. doi: 10.1371/journal.pone.0043853. Epub 2012 Aug 24.

23.

Myogenesis in dysferlin-deficient myoblasts is inhibited by an intrinsic inflammatory response.

Cohen TV, Cohen JE, Partridge TA.

Neuromuscul Disord. 2012 Jul;22(7):648-58. doi: 10.1016/j.nmd.2012.03.002. Epub 2012 May 3.

24.

Impending therapies for Duchenne muscular dystrophy.

Partridge TA.

Curr Opin Neurol. 2011 Oct;24(5):415-22. doi: 10.1097/WCO.0b013e32834aa3f1. Review.

PMID:
21892079
25.

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration.

Lepper C, Partridge TA, Fan CM.

Development. 2011 Sep;138(17):3639-46. doi: 10.1242/dev.067595.

26.

The isolated muscle fibre as a model of disuse atrophy: characterization using PhAct, a method to quantify f-actin.

Duddy WJ, Cohen T, Duguez S, Partridge TA.

Exp Cell Res. 2011 Aug 15;317(14):1979-93. doi: 10.1016/j.yexcr.2011.05.013. Epub 2011 May 20.

27.

Preclinical drug trials in the mdx mouse: assessment of reliable and sensitive outcome measures.

Spurney CF, Gordish-Dressman H, Guerron AD, Sali A, Pandey GS, Rawat R, Van Der Meulen JH, Cha HJ, Pistilli EE, Partridge TA, Hoffman EP, Nagaraju K.

Muscle Nerve. 2009 May;39(5):591-602. doi: 10.1002/mus.21211.

28.

A renaissance for antisense oligonucleotide drugs in neurology: exon skipping breaks new ground.

Yokota T, Takeda S, Lu QL, Partridge TA, Nakamura A, Hoffman EP.

Arch Neurol. 2009 Jan;66(1):32-8. doi: 10.1001/archneurol.2008.540. Review.

29.

Adenovirus-based targeting in myoblasts is hampered by nonhomologous vector integration.

Isman O, Roberts ML, Morgan JE, Graham IR, Goldring K, Lawrence-Watt DJ, Lu QL, Dunckley MG, Porter AC, Partridge TA, Dickson G.

Hum Gene Ther. 2008 Oct;19(10):1000-8. doi: 10.1089/hum.2008.063.

PMID:
18788904
30.

A population of myogenic stem cells that survives skeletal muscle aging.

Collins CA, Zammit PS, Ruiz AP, Morgan JE, Partridge TA.

Stem Cells. 2007 Apr;25(4):885-94. Epub 2007 Jan 11.

31.

Skeletal muscle stem cells express anti-apoptotic ErbB receptors during activation from quiescence.

Golding JP, Calderbank E, Partridge TA, Beauchamp JR.

Exp Cell Res. 2007 Jan 15;313(2):341-56. Epub 2006 Oct 26.

PMID:
17123512
32.

The skeletal muscle satellite cell: the stem cell that came in from the cold.

Zammit PS, Partridge TA, Yablonka-Reuveni Z.

J Histochem Cytochem. 2006 Nov;54(11):1177-91. Epub 2006 Aug 9. Review.

PMID:
16899758
33.

Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling.

Nagata Y, Partridge TA, Matsuda R, Zammit PS.

J Cell Biol. 2006 Jul 17;174(2):245-53.

34.

Expansion of revertant fibers in dystrophic mdx muscles reflects activity of muscle precursor cells and serves as an index of muscle regeneration.

Yokota T, Lu QL, Morgan JE, Davies KE, Fisher R, Takeda S, Partridge TA.

J Cell Sci. 2006 Jul 1;119(Pt 13):2679-87. Epub 2006 Jun 6.

35.

Pax7 and myogenic progression in skeletal muscle satellite cells.

Zammit PS, Relaix F, Nagata Y, Ruiz AP, Collins CA, Partridge TA, Beauchamp JR.

J Cell Sci. 2006 May 1;119(Pt 9):1824-32. Epub 2006 Apr 11.

36.

The human desmin locus: gene organization and LCR-mediated transcriptional control.

Tam JL, Triantaphyllopoulos K, Todd H, Raguz S, de Wit T, Morgan JE, Partridge TA, Makrinou E, Grosveld F, Antoniou M.

Genomics. 2006 Jun;87(6):733-46. Epub 2006 Mar 20.

37.

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology.

Alter J, Lou F, Rabinowitz A, Yin H, Rosenfeld J, Wilton SD, Partridge TA, Lu QL.

Nat Med. 2006 Feb;12(2):175-7. Epub 2006 Jan 29.

PMID:
16444267
38.

Self-renewal of the adult skeletal muscle satellite cell.

Collins CA, Partridge TA.

Cell Cycle. 2005 Oct;4(10):1338-41. Epub 2005 Oct 23.

PMID:
16177569
39.

Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche.

Collins CA, Olsen I, Zammit PS, Heslop L, Petrie A, Partridge TA, Morgan JE.

Cell. 2005 Jul 29;122(2):289-301.

40.

Stem cell therapies for neuromuscular diseases.

Partridge TA.

Acta Neurol Belg. 2004 Dec;104(4):141-7. Review.

PMID:
15742603
41.

Human muscle precursor cell regeneration in the mouse host is enhanced by growth factors.

Brimah K, Ehrhardt J, Mouly V, Butler-Browne GS, Partridge TA, Morgan JE.

Hum Gene Ther. 2004 Nov;15(11):1109-24.

PMID:
15610611
42.

Optimisation of ultrasound-mediated gene transfer (sonoporation) in skeletal muscle cells.

Liang HD, Lu QL, Xue SA, Halliwell M, Kodama T, Cosgrove DO, Stauss HJ, Partridge TA, Blomley MJ.

Ultrasound Med Biol. 2004 Nov;30(11):1523-9.

PMID:
15588963
43.

Heparin-binding EGF-like growth factor shows transient left-right asymmetrical expression in mouse myotome pairs.

Golding JP, Tsoni S, Dixon M, Yee KT, Partridge TA, Beauchamp JR, Gassmann M, Zammit PS.

Gene Expr Patterns. 2004 Nov;5(1):3-9.

PMID:
15533812
44.

Mouse myotomes pairs exhibit left-right asymmetric expression of MLC3F and alpha-skeletal actin.

Golding JP, Partridge TA, Beauchamp JR, King T, Brown NA, Gassmann M, Zammit PS.

Dev Dyn. 2004 Dec;231(4):795-800.

45.

Role of interleukin-1beta in acute inflammation and graft death after cell transplantation to the heart.

Suzuki K, Murtuza B, Beauchamp JR, Brand NJ, Barton PJ, Varela-Carver A, Fukushima S, Coppen SR, Partridge TA, Yacoub MH.

Circulation. 2004 Sep 14;110(11 Suppl 1):II219-24.

PMID:
15364866
46.

Myf5 expression in satellite cells and spindles in adult muscle is controlled by separate genetic elements.

Zammit PS, Carvajal JJ, Golding JP, Morgan JE, Summerbell D, Zolnerciks J, Partridge TA, Rigby PW, Beauchamp JR.

Dev Biol. 2004 Sep 15;273(2):454-65.

47.

Muscle satellite cells adopt divergent fates: a mechanism for self-renewal?

Zammit PS, Golding JP, Nagata Y, Hudon V, Partridge TA, Beauchamp JR.

J Cell Biol. 2004 Aug 2;166(3):347-57. Epub 2004 Jul 26.

48.

Regeneration of skeletal muscle from transplanted immortalised myoblasts is oligoclonal.

Cousins JC, Woodward KJ, Gross JG, Partridge TA, Morgan JE.

J Cell Sci. 2004 Jul 1;117(Pt 15):3259-69. Epub 2004 Jun 15.

49.

Dynamics and mediators of acute graft attrition after myoblast transplantation to the heart.

Suzuki K, Murtuza B, Beauchamp JR, Smolenski RT, Varela-Carver A, Fukushima S, Coppen SR, Partridge TA, Yacoub MH.

FASEB J. 2004 Jul;18(10):1153-5. Epub 2004 May 20.

PMID:
15155562
50.

Transplantation of skeletal myoblasts secreting an IL-1 inhibitor modulates adverse remodeling in infarcted murine myocardium.

Murtuza B, Suzuki K, Bou-Gharios G, Beauchamp JR, Smolenski RT, Partridge TA, Yacoub MH.

Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4216-21. Epub 2004 Mar 12.

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