Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 202

1.

Topical treatments for skin cancer.

Cullen JK, Simmons JL, Parsons PG, Boyle GM.

Adv Drug Deliv Rev. 2019 Nov 6. pii: S0169-409X(19)30193-0. doi: 10.1016/j.addr.2019.11.002. [Epub ahead of print]

PMID:
31705912
2.

Antibacterial 5α-Spirostane Saponins from the Fruit of Cordyline manners-suttoniae.

Tran TD, Olsson MA, Choudhury MA, McMillan DJ, Cullen JK, Parsons PG, Bernhardt PV, Reddell PW, Ogbourne SM.

J Nat Prod. 2019 Oct 25;82(10):2809-2817. doi: 10.1021/acs.jnatprod.9b00502. Epub 2019 Oct 9.

PMID:
31596585
3.

New Casbanes and the First trans-Cyclopropane seco-Casbane from the Australian Rainforest Plant Croton insularis.

Maslovskaya LA, Savchenko AI, Pierce CJ, Boyle GM, Gordon VA, Reddell PW, Parsons PG, Williams CM.

Chemistry. 2019 Jan 28;25(6):1525-1534. doi: 10.1002/chem.201804904. Epub 2019 Jan 2.

PMID:
30601580
4.

Corrigendum: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.

Chalmers BA, Xing H, Houston S, Clark C, Ghassabian S, Kuo A, Cao B, Reitsma A, Murray CP, Stok JE, Boyle GM, Pierce CJ, Littler SW, Winkler DA, Bernhardt PV, Pasay C, De Voss JJ, McCarthy J, Parsons PG, Walter GH, Smith MT, Cooper HM, Nilsson SK, Tsanaktsidis J, Savage GP, Williams CM.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8359. doi: 10.1002/anie.201711161. No abstract available.

PMID:
29975016
5.

Optimising intratumoral treatment of head and neck squamous cell carcinoma models with the diterpene ester Tigilanol tiglate.

Barnett CME, Broit N, Yap PY, Cullen JK, Parsons PG, Panizza BJ, Boyle GM.

Invest New Drugs. 2019 Feb;37(1):1-8. doi: 10.1007/s10637-018-0604-y. Epub 2018 Apr 18.

PMID:
29667135
6.

The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells.

Wilson D, Boyle GM, McIntyre L, Nolan MJ, Parsons PG, Smith JJ, Tribolet L, Loukas A, Liddell MJ, Rash LD, Daly NL.

Toxins (Basel). 2017 Oct 27;9(11). pii: E346. doi: 10.3390/toxins9110346.

7.

Furofuran lignans from the Simpson Desert species Eremophila macdonnellii.

Tan YP, Savchenko AI, Broit N, Boyle GM, Parsons PG, Williams CM.

Fitoterapia. 2018 Apr;126:93-97. doi: 10.1016/j.fitote.2017.06.004. Epub 2017 Jul 15.

PMID:
28596028
8.

The First Casbane Hydroperoxides EBC-304 and EBC-320 from the Australian Rainforest.

Maslovskaya LA, Savchenko AI, Gordon VA, Reddell PW, Pierce CJ, Parsons PG, Williams CM.

Chemistry. 2017 Jan 12;23(3):537-540. doi: 10.1002/chem.201604674. Epub 2016 Dec 7.

PMID:
27862493
9.

Expression profiling of cutaneous squamous cell carcinoma with perineural invasion implicates the p53 pathway in the process.

Warren TA, Broit N, Simmons JL, Pierce CJ, Chawla S, Lambie DL, Quagliotto G, Brown IS, Parsons PG, Panizza BJ, Boyle GM.

Sci Rep. 2016 Sep 26;6:34081. doi: 10.1038/srep34081.

10.

Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.

Chalmers BA, Xing H, Houston S, Clark C, Ghassabian S, Kuo A, Cao B, Reitsma A, Murray CE, Stok JE, Boyle GM, Pierce CJ, Littler SW, Winkler DA, Bernhardt PV, Pasay C, De Voss JJ, McCarthy J, Parsons PG, Walter GH, Smith MT, Cooper HM, Nilsson SK, Tsanaktsidis J, Savage GP, Williams CM.

Angew Chem Int Ed Engl. 2016 Mar 7;55(11):3580-5. doi: 10.1002/anie.201510675. Epub 2016 Feb 5. Erratum in: Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8359.

PMID:
26846616
11.

Ectopic expression of protein kinase C-β sensitizes head and neck squamous cell carcinoma to diterpene esters.

Adams RA, D'Souza MM, Pierce CJ, Korica N, Wallwork B, Parsons PG, Panizza B, Boyle GM.

Anticancer Res. 2015 Mar;35(3):1291-6.

PMID:
25750277
12.

Intra-lesional injection of the novel PKC activator EBC-46 rapidly ablates tumors in mouse models.

Boyle GM, D'Souza MM, Pierce CJ, Adams RA, Cantor AS, Johns JP, Maslovskaya L, Gordon VA, Reddell PW, Parsons PG.

PLoS One. 2014 Oct 1;9(10):e108887. doi: 10.1371/journal.pone.0108887. eCollection 2014.

13.

Unprecedented 1,14-seco-crotofolanes from Croton insularis: oxidative cleavage of crotofolin C by a putative homo-Baeyer-Villiger rearrangement.

Maslovskaya LA, Savchenko AI, Pierce CJ, Gordon VA, Reddell PW, Parsons PG, Williams CM.

Chemistry. 2014 Oct 27;20(44):14226-30. doi: 10.1002/chem.201404250. Epub 2014 Sep 18.

PMID:
25233878
14.

Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324.

Maslovskaya LA, Savchenko AI, Krenske EH, Gordon VA, Reddell PW, Pierce CJ, Parsons PG, Williams CM.

Chem Commun (Camb). 2014 Oct 21;50(82):12315-7. doi: 10.1039/c4cc05413j.

PMID:
25178400
15.

The value of nature's natural product library for the discovery of New Chemical Entities: the discovery of ingenol mebutate.

Ogbourne SM, Parsons PG.

Fitoterapia. 2014 Oct;98:36-44. doi: 10.1016/j.fitote.2014.07.002. Epub 2014 Jul 10. Review.

PMID:
25016953
16.

EBC-219: a new diterpene skeleton, crotinsulidane, from the Australian rainforest containing a bridgehead double bond.

Maslovskaya LA, Savchenko AI, Krenske EH, Pierce CJ, Gordon VA, Reddell PW, Parsons PG, Williams CM.

Angew Chem Int Ed Engl. 2014 Jul 1;53(27):7006-9. doi: 10.1002/anie.201310923. Epub 2014 May 5.

PMID:
24797625
17.

Multimodal polymer nanoparticles with combined 19F magnetic resonance and optical detection for tunable, targeted, multimodal imaging in vivo.

Rolfe BE, Blakey I, Squires O, Peng H, Boase NR, Alexander C, Parsons PG, Boyle GM, Whittaker AK, Thurecht KJ.

J Am Chem Soc. 2014 Feb 12;136(6):2413-9. doi: 10.1021/ja410351h. Epub 2014 Jan 29.

PMID:
24437730
18.

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment.

Dong Y, Stephens C, Walpole C, Swedberg JE, Boyle GM, Parsons PG, McGuckin MA, Harris JM, Clements JA.

PLoS One. 2013;8(2):e57056. doi: 10.1371/journal.pone.0057056. Epub 2013 Feb 25.

19.

Structure and bioactivity of steroidal saponins isolated from the roots of Chamaelirium luteum (false unicorn).

Challinor VL, Stuthe JM, Parsons PG, Lambert LK, Lehmann RP, Kitching W, De Voss JJ.

J Nat Prod. 2012 Aug 24;75(8):1469-79. doi: 10.1021/np300393y. Epub 2012 Aug 10.

PMID:
22880631
20.

Steroidal saponins from the roots of Smilax sp.: structure and bioactivity.

Challinor VL, Parsons PG, Chap S, White EF, Blanchfield JT, Lehmann RP, De Voss JJ.

Steroids. 2012 Apr;77(5):504-11. doi: 10.1016/j.steroids.2012.01.009. Epub 2012 Jan 21.

PMID:
22285850
21.

Potential molecular targets for inhibiting bone invasion by oral squamous cell carcinoma: a review of mechanisms.

Quan J, Johnson NW, Zhou G, Parsons PG, Boyle GM, Gao J.

Cancer Metastasis Rev. 2012 Jun;31(1-2):209-19. doi: 10.1007/s10555-011-9335-7. Review.

PMID:
22101806
22.

Selective, cytotoxic organoruthenium(II) full-sandwich complexes: a structural, computational and in vitro biological study.

Loughrey BT, Cunning BV, Healy PC, Brown CL, Parsons PG, Williams ML.

Chem Asian J. 2012 Jan 2;7(1):112-21. doi: 10.1002/asia.201100637. Epub 2011 Nov 17.

PMID:
22095971
23.

The sap from Euphorbia peplus is effective against human nonmelanoma skin cancers.

Ramsay JR, Suhrbier A, Aylward JH, Ogbourne S, Cozzi SJ, Poulsen MG, Baumann KC, Welburn P, Redlich GL, Parsons PG.

Br J Dermatol. 2011 Mar;164(3):633-6. doi: 10.1111/j.1365-2133.2010.10184.x. Epub 2011 Jan 27.

PMID:
21375515
24.

Isolation and confirmation of the proposed cleistanthol biogentic link from Croton insularis.

Maslovskaya LA, Savchenko AI, Gordon VA, Reddell PW, Pierce CJ, Parsons PG, Williams CM.

Org Lett. 2011 Mar 4;13(5):1032-5. doi: 10.1021/ol103083m. Epub 2011 Feb 4.

PMID:
21294576
25.

Serum omega-3 and omega-6 fatty acids and cutaneous p53 expression in an Australian population.

van der Pols JC, Xu C, Boyle GM, Hughes MC, Carr SJ, Parsons PG, Green AC.

Cancer Epidemiol Biomarkers Prev. 2011 Mar;20(3):530-6. doi: 10.1158/1055-9965.EPI-10-0961. Epub 2011 Jan 7.

26.

[4+2] cycloaddition reactions between 1,8-disubstituted cyclooctatetraenes and diazo dienophiles: stereoelectronic effects, anticancer properties and application to the synthesis of 7,8-substituted bicyclo[4.2.0]octa-2,4-dienes.

Grange RL, Gallen MJ, Schill H, Johns JP, Dong L, Parsons PG, Reddell PW, Gordon VA, Bernhardt PV, Williams CM.

Chemistry. 2010 Aug 2;16(29):8894-903. doi: 10.1002/chem.200903454.

PMID:
20572168
27.

Synthesis, structure and cytotoxicity studies of four-coordinate bis (cis-bis(diphenylphosphino)ethene) gold(I) complexes, [Au(dppey)(2)]X.

Healy PC, Loughrey BT, Williams ML, Parsons PG.

J Inorg Biochem. 2010 Jun;104(6):625-31. doi: 10.1016/j.jinorgbio.2010.02.003. Epub 2010 Mar 3.

PMID:
20346516
28.

Kallikrein-related peptidase 7 promotes multicellular aggregation via the alpha(5)beta(1) integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma.

Dong Y, Tan OL, Loessner D, Stephens C, Walpole C, Boyle GM, Parsons PG, Clements JA.

Cancer Res. 2010 Apr 1;70(7):2624-33. doi: 10.1158/0008-5472.CAN-09-3415. Epub 2010 Mar 23.

29.

Characterization of the Melanoma miRNAome by Deep Sequencing.

Stark MS, Tyagi S, Nancarrow DJ, Boyle GM, Cook AL, Whiteman DC, Parsons PG, Schmidt C, Sturm RA, Hayward NK.

PLoS One. 2010 Mar 12;5(3):e9685. doi: 10.1371/journal.pone.0009685.

30.

Reduced alphaB-crystallin staining in perineural invasion of head and neck cutaneous squamous cell carcinoma.

Solares CA, Boyle GM, Brown I, Parsons PG, Panizza B.

Otolaryngol Head Neck Surg. 2010 Mar;142(3 Suppl 1):S15-9. doi: 10.1016/j.otohns.2009.12.001.

PMID:
20176274
31.

Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer.

Merritt MA, Parsons PG, Newton TR, Martyn AC, Webb PM, Green AC, Papadimos DJ, Boyle GM.

BMC Cancer. 2009 Oct 23;9:378. doi: 10.1186/1471-2407-9-378.

32.

Anticancer agents from the Australian tropical rainforest: Spiroacetals EBC-23, 24, 25, 72, 73, 75 and 76.

Dong L, Schill H, Grange RL, Porzelle A, Johns JP, Parsons PG, Gordon VA, Reddell PW, Williams CM.

Chemistry. 2009 Oct 26;15(42):11307-18. doi: 10.1002/chem.200901525.

PMID:
19750529
33.

The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells.

Mason SA, Cozzi SJ, Pierce CJ, Pavey SJ, Parsons PG, Boyle GM.

Invest New Drugs. 2010 Oct;28(5):575-86. doi: 10.1007/s10637-009-9292-y. Epub 2009 Jul 28.

PMID:
19636513
34.

Novel organometallic cationic ruthenium(II) pentamethylcyclopentadienyl benzenesulfonamide complexes targeted to inhibit carbonic anhydrase.

Loughrey BT, Williams ML, Healy PC, Innocenti A, Vullo D, Supuran CT, Parsons PG, Poulsen SA.

J Biol Inorg Chem. 2009 Aug;14(6):935-45. doi: 10.1007/s00775-009-0506-8. Epub 2009 Apr 24.

PMID:
19390880
35.

H-cadherin expression reduces invasion of malignant melanoma.

Kuphal S, Martyn AC, Pedley J, Crowther LM, Bonazzi VF, Parsons PG, Bosserhoff AK, Hayward NK, Boyle GM.

Pigment Cell Melanoma Res. 2009 Jun;22(3):296-306. doi: 10.1111/j.1755-148X.2009.00568.x. Epub 2009 Apr 6.

PMID:
19368692
36.

Neural cell adhesion molecule expression: no correlation with perineural invasion in cutaneous squamous cell carcinoma of the head and neck.

Solares CA, Brown I, Boyle GM, Parsons PG, Panizza B.

Head Neck. 2009 Jun;31(6):802-6. doi: 10.1002/hed.21037.

PMID:
19283849
37.

Structure and absolute stereochemistry of the anticancer agent EBC-23 from the Australian rainforest.

Dong L, Gordon VA, Grange RL, Johns J, Parsons PG, Porzelle A, Reddell P, Schill H, Williams CM.

J Am Chem Soc. 2008 Nov 19;130(46):15262-3. doi: 10.1021/ja807133p. Epub 2008 Oct 25.

PMID:
18950180
38.

PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells.

Smith AG, Beaumont KA, Smit DJ, Thurber AE, Cook AL, Boyle GM, Parsons PG, Sturm RA, Muscat GE.

Int J Biochem Cell Biol. 2009 Apr;41(4):844-52. doi: 10.1016/j.biocel.2008.08.037. Epub 2008 Sep 6.

PMID:
18822385
39.

Selective cytotoxic Ru(II) arene Cp* complex salts [R-PhRuCp*](+)X(-) for X = BF4(-), PF6(-), and BPh4(-).

Loughrey BT, Healy PC, Parsons PG, Williams ML.

Inorg Chem. 2008 Oct 6;47(19):8589-91. doi: 10.1021/ic801159f. Epub 2008 Sep 11.

PMID:
18783214
40.

Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity.

Boyle GM, Pedley J, Martyn AC, Banducci KJ, Strutton GM, Brown DA, Breit SN, Parsons PG.

J Invest Dermatol. 2009 Feb;129(2):383-91. doi: 10.1038/jid.2008.270. Epub 2008 Aug 28.

41.

Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis.

Conway-Campbell BL, Wooh JW, Brooks AJ, Gordon D, Brown RJ, Lichanska AM, Chin HS, Barton CL, Boyle GM, Parsons PG, Jans DA, Waters MJ.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13331-6. Epub 2007 Aug 9.

42.
43.

Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid.

Kahnberg P, Lucke AJ, Glenn MP, Boyle GM, Tyndall JD, Parsons PG, Fairlie DP.

J Med Chem. 2006 Dec 28;49(26):7611-22.

PMID:
17181145
44.

Neutrophils are a key component of the antitumor efficacy of topical chemotherapy with ingenol-3-angelate.

Challacombe JM, Suhrbier A, Parsons PG, Jones B, Hampson P, Kavanagh D, Rainger GE, Morris M, Lord JM, Le TT, Hoang-Le D, Ogbourne SM.

J Immunol. 2006 Dec 1;177(11):8123-32.

45.
46.

Surfactant protein expression in human skin: evidence and implications.

Mo YK, Kankavi O, Masci PP, Mellick GD, Whitehouse MW, Boyle GM, Parsons PG, Roberts MS, Cross SE.

J Invest Dermatol. 2007 Feb;127(2):381-6. Epub 2006 Sep 28.

47.

The human genome and gene expression profiling.

Chin D, Boyle GM, Theile DR, Parsons PG, Coman WB.

J Plast Reconstr Aesthet Surg. 2006;59(9):902-11. Epub 2006 Mar 9. Review.

PMID:
16920579
48.

Head and neck cancer: past, present and future.

Chin D, Boyle GM, Porceddu S, Theile DR, Parsons PG, Coman WB.

Expert Rev Anticancer Ther. 2006 Jul;6(7):1111-8. Review.

PMID:
16831082
49.

New cysteine derivatives with antiproliferative activity on melanoma cells.

Lucke AJ, Boyle GM, Parsons PG, Fairlie DP.

Med Chem. 2006 Mar;2(2):123-32.

PMID:
16787361
50.

Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival.

Herath NI, Spanevello MD, Sabesan S, Newton T, Cummings M, Duffy S, Lincoln D, Boyle G, Parsons PG, Boyd AW.

BMC Cancer. 2006 Jun 1;6:144.

Supplemental Content

Loading ...
Support Center