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Items: 43


Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.

Stover DG, Parsons HA, Ha G, Freeman SS, Barry WT, Guo H, Choudhury AD, Gydush G, Reed SC, Rhoades J, Rotem D, Hughes ME, Dillon DA, Partridge AH, Wagle N, Krop IE, Getz G, Golub TR, Love JC, Winer EP, Tolaney SM, Lin NU, Adalsteinsson VA.

J Clin Oncol. 2018 Feb 20;36(6):543-553. doi: 10.1200/JCO.2017.76.0033. Epub 2018 Jan 3.


Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, Stewart C, Rosenberg M, Francis JM, Zhang CZ, Cohen O, Oh C, Ding H, Polak P, Lloyd M, Mahmud S, Helvie K, Merrill MS, Santiago RA, O'Connor EP, Jeong SH, Leeson R, Barry RM, Kramkowski JF, Zhang Z, Polacek L, Lohr JG, Schleicher M, Lipscomb E, Saltzman A, Oliver NM, Marini L, Waks AG, Harshman LC, Tolaney SM, Van Allen EM, Winer EP, Lin NU, Nakabayashi M, Taplin ME, Johannessen CM, Garraway LA, Golub TR, Boehm JS, Wagle N, Getz G, Love JC, Meyerson M.

Nat Commun. 2017 Nov 6;8(1):1324. doi: 10.1038/s41467-017-00965-y.


Acculturation and Perceptions of a Good Death Among Japanese Americans and Japanese Living in the U.S.

Mori M, Kuwama Y, Ashikaga T, Parsons HA, Miyashita M.

J Pain Symptom Manage. 2018 Jan;55(1):31-38. doi: 10.1016/j.jpainsymman.2017.08.010. Epub 2017 Aug 24.


Multiplexed Elimination of Wild-Type DNA and High-Resolution Melting Prior to Targeted Resequencing of Liquid Biopsies.

Ladas I, Fitarelli-Kiehl M, Song C, Adalsteinsson VA, Parsons HA, Lin NU, Wagle N, Makrigiorgos GM.

Clin Chem. 2017 Oct;63(10):1605-1613. doi: 10.1373/clinchem.2017.272849. Epub 2017 Jul 5.


Personalized Medicine in the Oncology Clinic: Implementation and Outcomes of the Johns Hopkins Molecular Tumor Board.

Dalton WB, Forde PM, Kang H, Connolly RM, Stearns V, Gocke CD, Eshleman JR, Axilbund J, Petry D, Geoghegan C, Wolff AC, Loeb DM, Pratilas CA, Meyer CF, Christenson ES, Slater SA, Ensminger J, Parsons HA, Park BH, Lauring J.

JCO Precis Oncol. 2017;2017. doi: 10.1200/PO.16.00046. Epub 2017 May 31.


Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer.

Parsons HA, Beaver JA, Cimino-Mathews A, Ali SM, Axilbund J, Chu D, Connolly RM, Cochran RL, Croessmann S, Clark TA, Gocke CD, Jeter SC, Kennedy MR, Lauring J, Lee J, Lipson D, Miller VA, Otto GA, Rosner GL, Ross JS, Slater S, Stephens PJ, VanDenBerg DA, Wolff AC, Young LE, Zabransky DJ, Zhang Z, Zorzi J, Stearns V, Park BH.

Clin Cancer Res. 2017 Jan 15;23(2):379-386. doi: 10.1158/1078-0432.CCR-16-1543. Epub 2016 Aug 3.


Circulating Plasma Tumor DNA.

Parsons HA, Beaver JA, Park BH.

Adv Exp Med Biol. 2016;882:259-76. doi: 10.1007/978-3-319-22909-6_11. Review.


The effects of curcumin (diferuloylmethane) on body composition of patients with advanced pancreatic cancer.

Parsons HA, Baracos VE, Hong DS, Abbruzzese J, Bruera E, Kurzrock R.

Oncotarget. 2016 Apr 12;7(15):20293-304. doi: 10.18632/oncotarget.7773.


HER2 missense mutations have distinct effects on oncogenic signaling and migration.

Zabransky DJ, Yankaskas CL, Cochran RL, Wong HY, Croessmann S, Chu D, Kavuri SM, Red Brewer M, Rosen DM, Dalton WB, Cimino-Mathews A, Cravero K, Button B, Kyker-Snowman K, Cidado J, Erlanger B, Parsons HA, Manto KM, Bose R, Lauring J, Arteaga CL, Konstantopoulos K, Park BH.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6205-14. doi: 10.1073/pnas.1516853112. Epub 2015 Oct 27.


NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability.

Croessmann S, Wong HY, Zabransky DJ, Chu D, Mendonca J, Sharma A, Mohseni M, Rosen DM, Scharpf RB, Cidado J, Cochran RL, Parsons HA, Dalton WB, Erlanger B, Button B, Cravero K, Kyker-Snowman K, Beaver JA, Kachhap S, Hurley PJ, Lauring J, Park BH.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11583-8. doi: 10.1073/pnas.1503683112. Epub 2015 Aug 31.


ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients.

Chu D, Paoletti C, Gersch C, VanDenBerg DA, Zabransky DJ, Cochran RL, Wong HY, Toro PV, Cidado J, Croessmann S, Erlanger B, Cravero K, Kyker-Snowman K, Button B, Parsons HA, Dalton WB, Gillani R, Medford A, Aung K, Tokudome N, Chinnaiyan AM, Schott A, Robinson D, Jacks KS, Lauring J, Hurley PJ, Hayes DF, Rae JM, Park BH.

Clin Cancer Res. 2016 Feb 15;22(4):993-9. doi: 10.1158/1078-0432.CCR-15-0943. Epub 2015 Aug 10.


[Information disclosure and decision making preferences of patients with advanced cancer in a Pain and Palliative Care Unit in Chile].

Palma A, Cartes F, González M, Villarroel L, Parsons HA, Yennurajalingam S, Bruera E.

Rev Med Chil. 2014 Jan;142(1):48-54. doi: 10.4067/S0034-98872014000100008. Spanish.


Decisional control preferences, disclosure of information preferences, and satisfaction among Hispanic patients with advanced cancer.

Noguera A, Yennurajalingam S, Torres-Vigil I, Parsons HA, Duarte ER, Palma A, Bunge S, Palmer JL, Bruera E.

J Pain Symptom Manage. 2014 May;47(5):896-905. doi: 10.1016/j.jpainsymman.2013.06.010. Epub 2013 Sep 12.


A pilot study of temsirolimus and body composition.

Veasey-Rodrigues H, Parsons HA, Janku F, Naing A, Wheler JJ, Tsimberidou AM, Kurzrock R.

J Cachexia Sarcopenia Muscle. 2013 Dec;4(4):259-65. doi: 10.1007/s13539-013-0113-y. Epub 2013 Jul 27.


Body composition and survival in the early clinical trials setting.

Veasey Rodrigues H, Baracos VE, Wheler JJ, Parsons HA, Hong DS, Naing A, Fu S, Falchoock G, Tsimberidou AM, Piha-Paul S, Chisholm G, Kurzrock R.

Eur J Cancer. 2013 Oct;49(15):3068-75. doi: 10.1016/j.ejca.2013.06.026. Epub 2013 Jul 15.


A multicenter survey of Hispanic caregiver preferences for patient decision control in the United States and Latin America.

Yennurajalingam S, Noguera A, Parsons HA, Torres-Vigil I, Duarte ER, Palma A, Bunge S, Palmer JL, Delgado-Guay MO, Bruera E.

Palliat Med. 2013 Jul;27(7):692-8. doi: 10.1177/0269216313486953. Epub 2013 May 13.


Decisional control preferences of Hispanic patients with advanced cancer from the United States and Latin America.

Yennurajalingam S, Parsons HA, Duarte ER, Palma A, Bunge S, Palmer JL, Delgado-Guay MO, Allo J, Bruera E.

J Pain Symptom Manage. 2013 Sep;46(3):376-85. doi: 10.1016/j.jpainsymman.2012.08.015. Epub 2012 Nov 22.


Outcomes of phase II clinical trials with single-agent therapies in advanced/metastatic non-small cell lung cancer published between 2000 and 2009.

Janku F, Berry DA, Gong J, Parsons HA, Stewart DJ, Kurzrock R.

Clin Cancer Res. 2012 Nov 15;18(22):6356-63. doi: 10.1158/1078-0432.CCR-12-0178. Epub 2012 Sep 26.


Spirituality, religiosity, and spiritual pain among caregivers of patients with advanced cancer.

Delgado-Guay MO, Parsons HA, Hui D, De la Cruz MG, Thorney S, Bruera E.

Am J Hosp Palliat Care. 2013 Aug;30(5):455-61. doi: 10.1177/1049909112458030. Epub 2012 Sep 4.


Frequency and predictors of patient deviation from prescribed opioids and barriers to opioid pain management in patients with advanced cancer.

Nguyen LM, Rhondali W, De la Cruz M, Hui D, Palmer L, Kang DH, Parsons HA, Bruera E.

J Pain Symptom Manage. 2013 Mar;45(3):506-16. doi: 10.1016/j.jpainsymman.2012.02.023. Epub 2012 Aug 30.


Concepts and definitions for "supportive care," "best supportive care," "palliative care," and "hospice care" in the published literature, dictionaries, and textbooks.

Hui D, De La Cruz M, Mori M, Parsons HA, Kwon JH, Torres-Vigil I, Kim SH, Dev R, Hutchins R, Liem C, Kang DH, Bruera E.

Support Care Cancer. 2013 Mar;21(3):659-85. doi: 10.1007/s00520-012-1564-y. Epub 2012 Aug 31. Review.


Reporting of funding sources and conflict of interest in the supportive and palliative oncology literature.

Hui D, Reddy A, Parsons HA, Bruera E.

J Pain Symptom Manage. 2012 Sep;44(3):421-30. doi: 10.1016/j.jpainsymman.2011.09.016. Epub 2012 Jul 7.


Body composition, symptoms, and survival in advanced cancer patients referred to a phase I service.

Parsons HA, Baracos VE, Dhillon N, Hong DS, Kurzrock R.

PLoS One. 2012;7(1):e29330. doi: 10.1371/journal.pone.0029330. Epub 2012 Jan 3.


Evaluation of the clinical relevance of body composition parameters in patients with cancer metastatic to the liver treated with hepatic arterial infusion chemotherapy.

Parsons HA, Tsimberidou AM, Pontikos M, Fu S, Hong D, Wen S, Baracos VE, Kurzrock R.

Nutr Cancer. 2012;64(2):206-17. doi: 10.1080/01635581.2012.638433. Epub 2012 Jan 9.


The lack of standard definitions in the supportive and palliative oncology literature.

Hui D, Mori M, Parsons HA, Kim SH, Li Z, Damani S, Bruera E.

J Pain Symptom Manage. 2012 Mar;43(3):582-92. doi: 10.1016/j.jpainsymman.2011.04.016. Epub 2011 Nov 21.


R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis.

Huang HJ, Angelo LS, Rodon J, Sun M, Kuenkele KP, Parsons HA, Trent JC, Kurzrock R.

PLoS One. 2011;6(10):e26060. doi: 10.1371/journal.pone.0026060. Epub 2011 Oct 11.


Changes in symptoms and inpatient mortality: a study in advanced cancer patients admitted to an acute palliative care unit in a comprehensive cancer center.

Mori M, Parsons HA, De la Cruz M, Elsayem A, Palla SL, Liu J, Li Z, Palmer L, Bruera E, Fadul NA.

J Palliat Med. 2011 Sep;14(9):1034-41. doi: 10.1089/jpm.2010.0544. Epub 2011 Aug 11.


Quantity, design, and scope of the palliative oncology literature.

Hui D, Parsons HA, Damani S, Fulton S, Liu J, Evans A, De La Cruz M, Bruera E.

Oncologist. 2011;16(5):694-703. doi: 10.1634/theoncologist.2010-0397. Epub 2011 Apr 6.


Undocumented alcoholism and its correlation with tobacco and illegal drug use in advanced cancer patients.

Dev R, Parsons HA, Palla S, Palmer JL, Del Fabbro E, Bruera E.

Cancer. 2011 Oct 1;117(19):4551-6. doi: 10.1002/cncr.26082. Epub 2011 Mar 28.


Spirituality, religiosity, and spiritual pain in advanced cancer patients.

Delgado-Guay MO, Hui D, Parsons HA, Govan K, De la Cruz M, Thorney S, Bruera E.

J Pain Symptom Manage. 2011 Jun;41(6):986-94. doi: 10.1016/j.jpainsymman.2010.09.017. Epub 2011 Mar 12.


Outcomes of patients with advanced non-small cell lung cancer treated in a phase I clinic.

Janku F, Tsimberidou AM, Wang X, Hong DS, Naing A, Gong J, Garrido-Laguna I, Parsons HA, Zinner RG, Kurzrock R.

Oncologist. 2011;16(3):327-35. doi: 10.1634/theoncologist.2010-0308. Epub 2011 Feb 21.


The frequency and correlates of spiritual distress among patients with advanced cancer admitted to an acute palliative care unit.

Hui D, de la Cruz M, Thorney S, Parsons HA, Delgado-Guay M, Bruera E.

Am J Hosp Palliat Care. 2011 Jun;28(4):264-70. doi: 10.1177/1049909110385917. Epub 2010 Nov 7.


Characteristics of patients who refuse do-not-resuscitate orders upon admission to an acute palliative care unit in a comprehensive cancer center.

Parsons HA, de la Cruz MJ, Zhukovsky DS, Hui D, Delgado-Guay MO, Akitoye AE, El Osta B, Palmer L, Palla SL, Bruera E.

Cancer. 2010 Jun 15;116(12):3061-70. doi: 10.1002/cncr.25045.


Single- vs. multiple-item instruments in the assessment of quality of life in patients with advanced cancer.

Bush SH, Parsons HA, Palmer JL, Li Z, Chacko R, Bruera E.

J Pain Symptom Manage. 2010 Mar;39(3):564-71. doi: 10.1016/j.jpainsymman.2009.08.006.


Comparison of functional outcomes in low- and high-grade astrocytoma rehabilitation inpatients.

Fu JB, Parsons HA, Shin KY, Guo Y, Konzen BS, Yadav RR, Smith DW.

Am J Phys Med Rehabil. 2010 Mar;89(3):205-12. doi: 10.1097/PHM.0b013e3181ca2306.


Methadone initiation and rotation in the outpatient setting for patients with cancer pain.

Parsons HA, de la Cruz M, El Osta B, Li Z, Calderon B, Palmer JL, Bruera E.

Cancer. 2010 Jan 15;116(2):520-8. doi: 10.1002/cncr.24754.


Placebo and nocebo effects in randomized double-blind clinical trials of agents for the therapy for fatigue in patients with advanced cancer.

de la Cruz M, Hui D, Parsons HA, Bruera E.

Cancer. 2010 Feb 1;116(3):766-74. doi: 10.1002/cncr.24751.


Predictors of inpatient mortality in an acute palliative care unit at a comprehensive cancer center.

Elsayem A, Mori M, Parsons HA, Munsell MF, Hui D, Delgado-Guay MO, Paraskevopoulos T, Fadul NA, Bruera E.

Support Care Cancer. 2010 Jan;18(1):67-76. doi: 10.1007/s00520-009-0631-5. Epub 2009 Apr 7.


Characteristics and correlates of dyspnea in patients with advanced cancer.

Reddy SK, Parsons HA, Elsayem A, Palmer JL, Bruera E.

J Palliat Med. 2009 Jan;12(1):29-36. doi: 10.1089/jpm.2008.0158.


Intermittent subcutaneous opioids for the management of cancer pain.

Parsons HA, Shukkoor A, Quan H, Delgado-Guay MO, Palmer JL, Fainsinger R, Bruera E.

J Palliat Med. 2008 Dec;11(10):1319-24. doi: 10.1089/jpm.2008.0155. No abstract available.


Symptom distress, interventions, and outcomes of intensive care unit cancer patients referred to a palliative care consult team.

Delgado-Guay MO, Parsons HA, Li Z, Palmer LJ, Bruera E.

Cancer. 2009 Jan 15;115(2):437-45. doi: 10.1002/cncr.24017.


Symptom distress in advanced cancer patients with anxiety and depression in the palliative care setting.

Delgado-Guay M, Parsons HA, Li Z, Palmer JL, Bruera E.

Support Care Cancer. 2009 May;17(5):573-9. doi: 10.1007/s00520-008-0529-7. Epub 2008 Nov 13.


Alcoholism screening in patients with advanced cancer: impact on symptom burden and opioid use.

Parsons HA, Delgado-Guay MO, El Osta B, Chacko R, Poulter V, Palmer JL, Bruera E.

J Palliat Med. 2008 Sep;11(7):964-8. doi: 10.1089/jpm.2008.0037.

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