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Items: 17


Combined p21-activated kinase and farnesyltransferase inhibitor treatment exhibits enhanced anti-proliferative activity on melanoma, colon and lung cancer cell lines.

Porcu G, Parsons AB, Di Giandomenico D, Lucisano G, Mosca MG, Boone C, Ragnini-Wilson A.

Mol Cancer. 2013 Aug 6;12(1):88. doi: 10.1186/1476-4598-12-88.


The tricarboxylic acid cycle in Shewanella oneidensis is independent of Fur and RyhB control.

Yang Y, McCue LA, Parsons AB, Feng S, Zhou J.

BMC Microbiol. 2010 Oct 16;10:264. doi: 10.1186/1471-2180-10-264.


Chemical-genetic approaches for exploring the mode of action of natural products.

Lopez A, Parsons AB, Nislow C, Giaever G, Boone C.

Prog Drug Res. 2008;66:237, 239-71. Review.


Characterization of the Shewanella oneidensis Fur gene: roles in iron and acid tolerance response.

Yang Y, Harris DP, Luo F, Wu L, Parsons AB, Palumbo AV, Zhou J.

BMC Genomics. 2008;9 Suppl 1:S11. doi: 10.1186/1471-2164-9-S1-S11.


Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.

Parsons AB, Lopez A, Givoni IE, Williams DE, Gray CA, Porter J, Chua G, Sopko R, Brost RL, Ho CH, Wang J, Ketela T, Brenner C, Brill JA, Fernandez GE, Lorenz TC, Payne GS, Ishihara S, Ohya Y, Andrews B, Hughes TR, Frey BJ, Graham TR, Andersen RJ, Boone C.

Cell. 2006 Aug 11;126(3):611-25.


The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation.

Tabuchi M, Audhya A, Parsons AB, Boone C, Emr SD.

Mol Cell Biol. 2006 Aug;26(15):5861-75.


Genomic approaches for identifying DNA damage response pathways in S. cerevisiae.

Chang M, Parsons AB, Sheikh BH, Boone C, Brown GW.

Methods Enzymol. 2006;409:213-35.


Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.

Zhao R, Davey M, Hsu YC, Kaplanek P, Tong A, Parsons AB, Krogan N, Cagney G, Mai D, Greenblatt J, Boone C, Emili A, Houry WA.

Cell. 2005 Mar 11;120(5):715-27.


Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway.

Sciorra VA, Audhya A, Parsons AB, Segev N, Boone C, Emr SD.

Mol Biol Cell. 2005 Feb;16(2):776-93. Epub 2004 Dec 1.


Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

Audhya A, Loewith R, Parsons AB, Gao L, Tabuchi M, Zhou H, Boone C, Hall MN, Emr SD.

EMBO J. 2004 Oct 1;23(19):3747-57. Epub 2004 Sep 16.


Fus1p interacts with components of the Hog1p mitogen-activated protein kinase and Cdc42p morphogenesis signaling pathways to control cell fusion during yeast mating.

Nelson B, Parsons AB, Evangelista M, Schaefer K, Kennedy K, Ritchie S, Petryshen TL, Boone C.

Genetics. 2004 Jan;166(1):67-77.


Global mapping of the yeast genetic interaction network.

Tong AH, Lesage G, Bader GD, Ding H, Xu H, Xin X, Young J, Berriz GF, Brost RL, Chang M, Chen Y, Cheng X, Chua G, Friesen H, Goldberg DS, Haynes J, Humphries C, He G, Hussein S, Ke L, Krogan N, Li Z, Levinson JN, Lu H, Ménard P, Munyana C, Parsons AB, Ryan O, Tonikian R, Roberts T, Sdicu AM, Shapiro J, Sheikh B, Suter B, Wong SL, Zhang LV, Zhu H, Burd CG, Munro S, Sander C, Rine J, Greenblatt J, Peter M, Bretscher A, Bell G, Roth FP, Brown GW, Andrews B, Bussey H, Boone C.

Science. 2004 Feb 6;303(5659):808-13.


Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways.

Parsons AB, Brost RL, Ding H, Li Z, Zhang C, Sheikh B, Brown GW, Kane PM, Hughes TR, Boone C.

Nat Biotechnol. 2004 Jan;22(1):62-9. Epub 2003 Dec 7.


Yeast genomics and proteomics in drug discovery and target validation.

Parsons AB, Geyer R, Hughes TR, Boone C.

Prog Cell Cycle Res. 2003;5:159-66. Review.


Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae.

Anderson JB, Sirjusingh C, Parsons AB, Boone C, Wickens C, Cowen LE, Kohn LM.

Genetics. 2003 Apr;163(4):1287-98.


Systematic genetic analysis with ordered arrays of yeast deletion mutants.

Tong AH, Evangelista M, Parsons AB, Xu H, Bader GD, Pagé N, Robinson M, Raghibizadeh S, Hogue CW, Bussey H, Andrews B, Tyers M, Boone C.

Science. 2001 Dec 14;294(5550):2364-8.


Production of extracellular polysaccharide matrix by Zoogloea ramigera.

Parsons AB, Dugan PR.

Appl Microbiol. 1971 Apr;21(4):657-61.

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