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Items: 26

1.

Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1.

Dowden J, Pike RA, Parry RV, Hong W, Muhsen UA, Ward SG.

Org Biomol Chem. 2011 Oct 26;9(22):7814-21. doi: 10.1039/c1ob06100c. Epub 2011 Sep 27.

PMID:
21952734
2.

Evidence that the lipid phosphatase SHIP-1 regulates T lymphocyte morphology and motility.

Harris SJ, Parry RV, Foster JG, Blunt MD, Wang A, Marelli-Berg F, Westwick J, Ward SG.

J Immunol. 2011 Apr 15;186(8):4936-45. doi: 10.4049/jimmunol.1002350. Epub 2011 Mar 14.

3.

Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases.

Dowden J, Hong W, Parry RV, Pike RA, Ward SG.

Bioorg Med Chem Lett. 2010 Apr 1;20(7):2103-5. doi: 10.1016/j.bmcl.2010.02.069. Epub 2010 Feb 20.

PMID:
20219369
4.

Protein arginine methylation: a new handle on T lymphocytes?

Parry RV, Ward SG.

Trends Immunol. 2010 Apr;31(4):164-9. doi: 10.1016/j.it.2010.01.006. Epub 2010 Feb 22. Review.

PMID:
20181528
5.

Fine tuning T lymphocytes: a role for the lipid phosphatase SHIP-1.

Parry RV, Harris SJ, Ward SG.

Biochim Biophys Acta. 2010 Mar;1804(3):592-7. doi: 10.1016/j.bbapap.2009.09.019. Epub 2009 Sep 25. Review.

PMID:
19782768
6.

Genetic engineering of T cells for adoptive immunotherapy.

Varela-Rohena A, Carpenito C, Perez EE, Richardson M, Parry RV, Milone M, Scholler J, Hao X, Mexas A, Carroll RG, June CH, Riley JL.

Immunol Res. 2008;42(1-3):166-81. doi: 10.1007/s12026-008-8057-6. Review.

7.

Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes.

Harris SJ, Parry RV, Westwick J, Ward SG.

J Biol Chem. 2008 Feb 1;283(5):2465-9. Epub 2007 Dec 10. Review.

8.

PI3Kgamma is the dominant isoform involved in migratory responses of human T lymphocytes: effects of ex vivo maintenance and limitations of non-viral delivery of siRNA.

Smith LD, Hickman ES, Parry RV, Westwick J, Ward SG.

Cell Signal. 2007 Dec;19(12):2528-39. Epub 2007 Aug 22.

PMID:
17900864
9.

Signalling to suit function: tailoring phosphoinositide 3-kinase during T-cell activation.

Parry RV, Riley JL, Ward SG.

Trends Immunol. 2007 Apr;28(4):161-8. Epub 2007 Mar 1. Review.

PMID:
17336157
11.

Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells.

Kovacs B, Parry RV, Ma Z, Fan E, Shivers DK, Freiberg BA, Thomas AK, Rutherford R, Rumbley CA, Riley JL, Finkel TH.

J Immunol. 2005 Dec 15;175(12):7848-54.

12.

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms.

Parry RV, Chemnitz JM, Frauwirth KA, Lanfranco AR, Braunstein I, Kobayashi SV, Linsley PS, Thompson CB, Riley JL.

Mol Cell Biol. 2005 Nov;25(21):9543-53.

14.

Calcium-independent calcineurin regulation.

Parry RV, June CH.

Nat Immunol. 2003 Sep;4(9):821-3. No abstract available.

PMID:
12942079
16.

The CD28 signaling pathway regulates glucose metabolism.

Frauwirth KA, Riley JL, Harris MH, Parry RV, Rathmell JC, Plas DR, Elstrom RL, June CH, Thompson CB.

Immunity. 2002 Jun;16(6):769-77.

17.

CD28 stimulates tyrosine phosphorylation, cellular redistribution and catalytic activity of the inositol lipid 5-phosphatase SHIP.

Edmunds C, Parry RV, Burgess SJ, Reaves B, Ward SG.

Eur J Immunol. 1999 Nov;29(11):3507-15.

18.

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

Parry RV, Reif K, Smith G, Sansom DM, Hemmings BA, Ward SG.

Eur J Immunol. 1997 Oct;27(10):2495-501.

PMID:
9368602
20.

Phorbol esters modulate the coupling of the T cell costimulatory molecule CD28 to phosphatidylinositol 3-kinase.

Parry RV, Boulougouris G, Sansom DM, Ward SG.

Biochem Soc Trans. 1997 May;25(2):305S. No abstract available.

PMID:
9191349
21.

A p38 MAP kinase inhibitor SB203580 inhibits CD28-dependent T cell proliferation and IL-2 production.

Ward SG, Parry RV, Matthews J, O'Neill L.

Biochem Soc Trans. 1997 May;25(2):304S. No abstract available.

PMID:
9191348
22.

Activation of phosphatidylinositol 3-kinase following Fas engagement is not required for Fas-mediated apoptosis in Jurkat T cells.

McLeod JD, Walker LS, Parry RV, Ward SG, Sansom DM.

Biochem Soc Trans. 1997 May;25(2):241S. No abstract available.

PMID:
9191285
23.

Involvement of phosphatidylinositol 3-kinase in the activation of p70 S6 kinase by the T cell costimulatory molecule CD28.

Parry RV, Ward SG.

Biochem Soc Trans. 1996 Feb;24(1):88S. No abstract available.

PMID:
8674770
24.

Characterisation of a serine/threonine kinase which mediates CD28 phosphorylation following activation by B7.1.

Parry RV, Westwick J, Ward SG.

Biochem Soc Trans. 1996 Feb;24(1):87S. No abstract available.

PMID:
8674769
25.

Characterization of low Mr zona pellucida binding proteins from boar spermatozoa and seminal plasma.

Parry RV, Barker PJ, Jones R.

Mol Reprod Dev. 1992 Sep;33(1):108-15.

PMID:
1510840
26.

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