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Items: 1 to 50 of 69

1.

From Natural Killer Cell Receptor Discovery to Characterization of Natural Killer Cell Defects in Primary Immunodeficiencies.

Tabellini G, Patrizi O, Dobbs K, Lougaris V, Baronio M, Coltrini D, Plebani A, Badolato R, Notarangelo LD, Parolini S.

Front Immunol. 2019 Jul 24;10:1757. doi: 10.3389/fimmu.2019.01757. eCollection 2019. Review.

2.

Strengthening the AntiTumor NK Cell Function for the Treatment of Ovarian Cancer.

Greppi M, Tabellini G, Patrizi O, Candiani S, Decensi A, Parolini S, Sivori S, Pesce S, Paleari L, Marcenaro E.

Int J Mol Sci. 2019 Feb 19;20(4). pii: E890. doi: 10.3390/ijms20040890. Review.

3.

A monoallelic activating mutation in RAC2 resulting in a combined immunodeficiency.

Lougaris V, Chou J, Beano A, Wallace JG, Baronio M, Gazzurelli L, Lorenzini T, Moratto D, Tabellini G, Parolini S, Seleman M, Stafstrom K, Xu H, Harris C, Geha RS, Plebani A.

J Allergy Clin Immunol. 2019 Apr;143(4):1649-1653.e3. doi: 10.1016/j.jaci.2019.01.001. Epub 2019 Jan 14. No abstract available.

PMID:
30654050
4.

CTLA-4 regulates human Natural Killer cell effector functions.

Lougaris V, Tabellini G, Baronio M, Patrizi O, Gazzurelli L, Mitsuiki N, Pozzi MR, Grimbacher B, Parolini S, Plebani A.

Clin Immunol. 2018 Sep;194:43-45. doi: 10.1016/j.clim.2018.06.010. Epub 2018 Jun 30. No abstract available.

PMID:
29966715
5.

Response to the Letter to the Editor Regarding "Functional evaluation of natural killer cell cytotoxic activity in NFKB-2 mutated patients".

Lougaris V, Tabellini G, Baronio M, Patrizi O, Parolini S, Plebani A.

Immunol Lett. 2018 Aug;200:16-17. doi: 10.1016/j.imlet.2018.05.004. Epub 2018 May 30. No abstract available.

PMID:
29859209
6.

Fetal size and growth velocity in chronic hypertension.

Frusca T, Parolini S, Dall'Asta A, Hassan WA, Vitulo A, Gillett A, Pasupathy D, Lees CC.

Pregnancy Hypertens. 2017 Oct;10:101-106. doi: 10.1016/j.preghy.2017.06.007. Epub 2017 Jun 21.

7.

In vitro treatment with concentrated growth factors (CGF) and sodium orthosilicate positively affects cell renewal in three different human cell lines.

Bonazza V, Borsani E, Buffoli B, Parolini S, Inchingolo F, Rezzani R, Rodella LF.

Cell Biol Int. 2018 Mar;42(3):353-364. doi: 10.1002/cbin.10908. Epub 2017 Nov 20.

PMID:
29105212
8.

Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Dobbs K, Tabellini G, Calzoni E, Patrizi O, Martinez P, Giliani SC, Moratto D, Al-Herz W, Cancrini C, Cowan M, Bleesing J, Booth C, Buchbinder D, Burns SO, Chatila TA, Chou J, Daza-Cajigal V, Ott de Bruin LM, de la Morena MT, Di Matteo G, Finocchi A, Geha R, Goyal RK, Hayward A, Holland S, Huang CH, Kanariou MG, King A, Kaplan B, Kleva A, Kuijpers TW, Lee BW, Lougaris V, Massaad M, Meyts I, Morsheimer M, Neven B, Pai SY, Parvaneh N, Plebani A, Prockop S, Reisli I, Soh JY, Somech R, Torgerson TR, Kim YJ, Walter JE, Gennery AR, Keles S, Manis JP, Marcenaro E, Moretta A, Parolini S, Notarangelo LD.

Front Immunol. 2017 Oct 10;8:1244. doi: 10.3389/fimmu.2017.01244. eCollection 2017.

9.

Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Dobbs K, Tabellini G, Calzoni E, Patrizi O, Martinez P, Giliani SC, Moratto D, Al-Herz W, Cancrini C, Cowan M, Bleesing J, Booth C, Buchbinder D, Burns SO, Chatila TA, Chou J, Daza-Cajigal V, Ott de Bruin LM, de la Morena M, Di Matteo G, Finocchi A, Geha R, Goyal RK, Hayward A, Holland S, Huang CH, Kanariou MG, King A, Kaplan B, Kleva A, Kuijpers TW, Lee BW, Lougaris V, Massaad M, Meyts I, Morsheimer M, Neven B, Pai SY, Parvaneh N, Plebani A, Prockop S, Reisli I, Soh JY, Somech R, Torgerson TR, Kim YJ, Walter JE, Gennery AR, Keles S, Manis JP, Marcenaro E, Moretta A, Parolini S, Notarangelo LD.

Front Immunol. 2017 Jul 17;8:798. doi: 10.3389/fimmu.2017.00798. eCollection 2017. Erratum in: Front Immunol. 2017 Oct 10;8:1244.

10.

Impaired natural killer cell functions in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.

Tabellini G, Vairo D, Scomodon O, Tamassia N, Ferraro RM, Patrizi O, Gasperini S, Soresina A, Giardino G, Pignata C, Lougaris V, Plebani A, Dotta L, Cassatella MA, Parolini S, Badolato R.

J Allergy Clin Immunol. 2017 Aug;140(2):553-564.e4. doi: 10.1016/j.jaci.2016.10.051. Epub 2017 Jan 6.

PMID:
28069426
11.

NFKB1 regulates human NK cell maturation and effector functions.

Lougaris V, Patrizi O, Baronio M, Tabellini G, Tampella G, Damiati E, Frede N, van der Meer JWM, Fliegauf M, Grimbacher B, Parolini S, Plebani A.

Clin Immunol. 2017 Feb;175:99-108. doi: 10.1016/j.clim.2016.11.012. Epub 2016 Dec 3.

PMID:
27923702
12.

Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization.

Pesce S, Greppi M, Tabellini G, Rampinelli F, Parolini S, Olive D, Moretta L, Moretta A, Marcenaro E.

J Allergy Clin Immunol. 2017 Jan;139(1):335-346.e3. doi: 10.1016/j.jaci.2016.04.025. Epub 2016 May 27.

PMID:
27372564
13.

p85α is an intrinsic regulator of human natural killer cell effector functions.

Lougaris V, Patrizi O, Baronio M, Tabellini G, Tampella G, Lanzi G, Salvini F, Trizzino A, Parolini S, Plebani A.

J Allergy Clin Immunol. 2016 Aug;138(2):605-608.e3. doi: 10.1016/j.jaci.2016.01.026. Epub 2016 Mar 23. No abstract available.

PMID:
27016802
14.

Pseudorabies Virus US3 Protein Kinase Protects Infected Cells from NK Cell-Mediated Lysis via Increased Binding of the Inhibitory NK Cell Receptor CD300a.

Grauwet K, Vitale M, De Pelsmaeker S, Jacob T, Laval K, Moretta L, Parodi M, Parolini S, Cantoni C, Favoreel HW.

J Virol. 2015 Nov 18;90(3):1522-33. doi: 10.1128/JVI.02902-15. Print 2016 Feb 1.

15.

Natural killer cell hyporesponsiveness and impaired development in a CD247-deficient patient.

Valés-Gómez M, Esteso G, Aydogmus C, Blázquez-Moreno A, Marín AV, Briones AC, Garcillán B, García-Cuesta EM, López Cobo S, Haskologlu S, Moraru M, Cipe F, Dobbs K, Dogu F, Parolini S, Notarangelo LD, Vilches C, Recio MJ, Regueiro JR, Ikinciogullari A, Reyburn HT.

J Allergy Clin Immunol. 2016 Mar;137(3):942-5.e4. doi: 10.1016/j.jaci.2015.07.051. Epub 2015 Nov 2. No abstract available.

PMID:
26542031
16.

B7-H6-mediated downregulation of NKp30 in NK cells contributes to ovarian carcinoma immune escape.

Pesce S, Tabellini G, Cantoni C, Patrizi O, Coltrini D, Rampinelli F, Matta J, Vivier E, Moretta A, Parolini S, Marcenaro E.

Oncoimmunology. 2015 Jan 22;4(4):e1001224. eCollection 2015 Apr.

17.

Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections.

Dobbs K, Domínguez Conde C, Zhang SY, Parolini S, Audry M, Chou J, Haapaniemi E, Keles S, Bilic I, Okada S, Massaad MJ, Rounioja S, Alwahadneh AM, Serwas NK, Capuder K, Çiftçi E, Felgentreff K, Ohsumi TK, Pedergnana V, Boisson B, Haskoloğlu Ş, Ensari A, Schuster M, Moretta A, Itan Y, Patrizi O, Rozenberg F, Lebon P, Saarela J, Knip M, Petrovski S, Goldstein DB, Parrott RE, Savas B, Schambach A, Tabellini G, Bock C, Chatila TA, Comeau AM, Geha RS, Abel L, Buckley RH, İkincioğulları A, Al-Herz W, Helminen M, Doğu F, Casanova JL, Boztuğ K, Notarangelo LD.

N Engl J Med. 2015 Jun 18;372(25):2409-22. doi: 10.1056/NEJMoa1413462.

18.

Defective natural killer-cell cytotoxic activity in NFKB2-mutated CVID-like disease.

Lougaris V, Tabellini G, Vitali M, Baronio M, Patrizi O, Tampella G, Biasini A, Moratto D, Parolini S, Plebani A.

J Allergy Clin Immunol. 2015 Jun;135(6):1641-3. doi: 10.1016/j.jaci.2014.11.038. Epub 2015 Jan 17. No abstract available.

PMID:
25605273
19.

Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis.

Meazza R, Tuberosa C, Cetica V, Falco M, Parolini S, Grieve S, Griffiths GM, Sieni E, Marcenaro S, Micalizzi C, Montin D, Fagioli F, Moretta A, Mingari MC, Moretta L, Notarangelo LD, Bottino C, Aricò M, Pende D.

J Allergy Clin Immunol. 2014 Dec;134(6):1381-1387.e7. doi: 10.1016/j.jaci.2014.04.043. Epub 2014 Jun 27.

PMID:
24985396
20.

Primitive neuroectodermal tumor in an ovarian cystic teratoma: natural killer and neuroblastoma cell analysis.

Tabellini G, Benassi M, Marcenaro E, Coltrini D, Patrizi O, Ricotta D, Rampinelli F, Moretta A, Parolini S.

Case Rep Oncol. 2014 Jan 24;7(1):70-8. doi: 10.1159/000357802. eCollection 2014 Jan.

21.

XLP1 inhibitory effect by 2B4 does not affect DNAM-1 and NKG2D activating pathways in NK cells.

Meazza R, Tuberosa C, Cetica V, Falco M, Loiacono F, Parolini S, Micalizzi C, Moretta A, Mingari MC, Moretta L, Bottino C, Aricò M, Pende D.

Eur J Immunol. 2014 May;44(5):1526-34. doi: 10.1002/eji.201344312. Epub 2014 Feb 27.

22.

Activin A as a mediator of NK-dendritic cell functional interactions.

Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S.

J Immunol. 2014 Feb 1;192(3):1241-8. doi: 10.4049/jimmunol.1301487. Epub 2014 Jan 6.

23.

Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects.

Lorenzi L, Tabellini G, Vermi W, Moratto D, Porta F, Notarangelo LD, Patrizi O, Sozzani S, de Saint Basile G, Latour S, Pace D, Lonardi S, Facchetti F, Badolato R, Parolini S.

PLoS One. 2013 Nov 26;8(11):e80131. doi: 10.1371/journal.pone.0080131. eCollection 2013.

24.

Effects of opioid therapy on human natural killer cells.

Tabellini G, Borsani E, Benassi M, Patrizi O, Ricotta D, Caimi L, Lanzi R, Micheli F, Iorno V, Bettaglio R, Rezzani R, Rodella LF, Parolini S.

Int Immunopharmacol. 2014 Jan;18(1):169-74. doi: 10.1016/j.intimp.2013.11.015. Epub 2013 Nov 25.

PMID:
24287448
25.

Clinical, laboratory and molecular signs of immunodeficiency in patients with partial oculo-cutaneous albinism.

Dotta L, Parolini S, Prandini A, Tabellini G, Antolini M, Kingsmore SF, Badolato R.

Orphanet J Rare Dis. 2013 Oct 17;8:168. doi: 10.1186/1750-1172-8-168. Review.

26.

Exome sequencing reveals a pallidin mutation in a Hermansky-Pudlak-like primary immunodeficiency syndrome.

Badolato R, Prandini A, Caracciolo S, Colombo F, Tabellini G, Giacomelli M, Cantarini ME, Pession A, Bell CJ, Dinwiddie DL, Miller NA, Hateley SL, Saunders CJ, Zhang L, Schroth GP, Plebani A, Parolini S, Kingsmore SF.

Blood. 2012 Mar 29;119(13):3185-7. doi: 10.1182/blood-2012-01-404350. No abstract available.

27.

A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP.

Lanzi G, Moratto D, Vairo D, Masneri S, Delmonte O, Paganini T, Parolini S, Tabellini G, Mazza C, Savoldi G, Montin D, Martino S, Tovo P, Pessach IM, Massaad MJ, Ramesh N, Porta F, Plebani A, Notarangelo LD, Geha RS, Giliani S.

J Exp Med. 2012 Jan 16;209(1):29-34. doi: 10.1084/jem.20110896. Epub 2012 Jan 9.

28.

NK cells and their receptors during viral infections.

Marcenaro E, Carlomagno S, Pesce S, Della Chiesa M, Parolini S, Moretta A, Sivori S.

Immunotherapy. 2011 Sep;3(9):1075-86. doi: 10.2217/imt.11.99. Review.

PMID:
21913830
29.

Severe impairment of IFN-γ and IFN-α responses in cells of a patient with a novel STAT1 splicing mutation.

Vairo D, Tassone L, Tabellini G, Tamassia N, Gasperini S, Bazzoni F, Plebani A, Porta F, Notarangelo LD, Parolini S, Giliani S, Badolato R.

Blood. 2011 Aug 18;118(7):1806-17. doi: 10.1182/blood-2011-01-330571. Epub 2011 Jul 19.

30.

GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues.

Della Chiesa M, Falco M, Parolini S, Bellora F, Petretto A, Romeo E, Balsamo M, Gambarotti M, Scordamaglia F, Tabellini G, Facchetti F, Vermi W, Bottino C, Moretta A, Vitale M.

Int Immunol. 2010 Feb;22(2):91-100. doi: 10.1093/intimm/dxp116. Epub 2009 Dec 14.

PMID:
20008459
31.

Novel insights from adaptor protein 3 complex deficiency.

Badolato R, Parolini S.

J Allergy Clin Immunol. 2007 Oct;120(4):735-41; quiz 742-3. Review.

PMID:
17931556
32.

NK cells at the interface between innate and adaptive immunity.

Moretta A, Marcenaro E, Parolini S, Ferlazzo G, Moretta L.

Cell Death Differ. 2008 Feb;15(2):226-33. Epub 2007 Jun 1. Review.

33.

Functional characterization of natural killer cells in type I leukocyte adhesion deficiency.

Castriconi R, Dondero A, Cantoni C, Della Chiesa M, Prato C, Nanni M, Fiorini M, Notarangelo L, Parolini S, Moretta L, Notarangelo L, Moretta A, Bottino C.

Blood. 2007 Jun 1;109(11):4873-81. Epub 2007 Feb 1.

34.

The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues.

Parolini S, Santoro A, Marcenaro E, Luini W, Massardi L, Facchetti F, Communi D, Parmentier M, Majorana A, Sironi M, Tabellini G, Moretta A, Sozzani S.

Blood. 2007 May 1;109(9):3625-32. Epub 2007 Jan 3.

35.

Innate immunity defects in Hermansky-Pudlak type 2 syndrome.

Fontana S, Parolini S, Vermi W, Booth S, Gallo F, Donini M, Benassi M, Gentili F, Ferrari D, Notarangelo LD, Cavadini P, Marcenaro E, Dusi S, Cassatella M, Facchetti F, Griffiths GM, Moretta A, Notarangelo LD, Badolato R.

Blood. 2006 Jun 15;107(12):4857-64. Epub 2006 Feb 28.

36.

Reduced thymic output, increased spontaneous apoptosis and oligoclonal B cells in polyethylene glycol-adenosine deaminase-treated patients.

Malacarne F, Benicchi T, Notarangelo LD, Mori L, Parolini S, Caimi L, Hershfield M, Notarangelo LD, Imberti L.

Eur J Immunol. 2005 Nov;35(11):3376-86.

37.

Distinctive lack of CD48 expression in subsets of human dendritic cells tunes NK cell activation.

Morandi B, Costa R, Falco M, Parolini S, De Maria A, Ratto G, Mingari MC, Melioli G, Moretta A, Ferlazzo G.

J Immunol. 2005 Sep 15;175(6):3690-7.

38.

IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumors.

Marcenaro E, Della Chiesa M, Bellora F, Parolini S, Millo R, Moretta L, Moretta A.

J Immunol. 2005 Apr 1;174(7):3992-8.

39.

Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect.

Gismondi A, Cifaldi L, Mazza C, Giliani S, Parolini S, Morrone S, Jacobelli J, Bandiera E, Notarangelo L, Santoni A.

Blood. 2004 Jul 15;104(2):436-43. Epub 2004 Mar 4.

40.

IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors.

Sivori S, Cantoni C, Parolini S, Marcenaro E, Conte R, Moretta L, Moretta A.

Eur J Immunol. 2003 Dec;33(12):3439-47.

41.

CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity.

Marcenaro E, Augugliaro R, Falco M, Castriconi R, Parolini S, Sivori S, Romeo E, Millo R, Moretta L, Bottino C, Moretta A.

Eur J Immunol. 2003 Dec;33(12):3367-76.

42.

Selective cross-talk among natural cytotoxicity receptors in human natural killer cells.

Augugliaro R, Parolini S, Castriconi R, Marcenaro E, Cantoni C, Nanni M, Moretta L, Moretta A, Bottino C.

Eur J Immunol. 2003 May;33(5):1235-41.

43.

Killer cell immunoglobulin-like receptor expression delineates in situ Sézary syndrome lymphocytes.

Wechsler J, Bagot M, Nikolova M, Parolini S, Martin-Garcia N, Boumsell L, Moretta A, Bensussan A.

J Pathol. 2003 Jan;199(1):77-83.

PMID:
12474229
44.

Cellular and molecular pathogenesis of X-linked lymphoproliferative disease.

Moretta A, Bottino C, Parolini S, Moretta L, Biassoni R, Notarangelo LD.

Curr Opin Allergy Clin Immunol. 2001 Dec;1(6):513-7. Review.

PMID:
11964734
45.

Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation.

Sivori S, Falco M, Marcenaro E, Parolini S, Biassoni R, Bottino C, Moretta L, Moretta A.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4526-31. Epub 2002 Mar 26.

46.

X-linked lymphoproliferative disease: the dark side of 2b4 function.

Bottino C, Parolini S, Biassoni R, Falco M, Notarangelo L, Moretta A.

Adv Exp Med Biol. 2001;495:63-7. No abstract available.

PMID:
11774610
47.

Human natural killer cell receptors and co-receptors.

Biassoni R, Cantoni C, Pende D, Sivori S, Parolini S, Vitale M, Bottino C, Moretta A.

Immunol Rev. 2001 Jun;181:203-14. Review.

PMID:
11513142
48.

NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease.

Bottino C, Falco M, Parolini S, Marcenaro E, Augugliaro R, Sivori S, Landi E, Biassoni R, Notarangelo LD, Moretta L, Moretta A.

J Exp Med. 2001 Aug 6;194(3):235-46. Erratum in: J Exp Med 2001 Sep 3;194(5):following 703.

49.

Identification of NKp80, a novel triggering molecule expressed by human NK cells.

Vitale M, Falco M, Castriconi R, Parolini S, Zambello R, Semenzato G, Biassoni R, Bottino C, Moretta L, Moretta A.

Eur J Immunol. 2001 Jan;31(1):233-42.

50.

Triggering receptors involved in natural killer cell-mediated cytotoxicity against choriocarcinoma cell lines.

Sivori S, Parolini S, Marcenaro E, Millo R, Bottino C, Moretta A.

Hum Immunol. 2000 Nov;61(11):1055-8.

PMID:
11137207

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