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Items: 1 to 50 of 96

1.

Tezepelumab in Adults with Uncontrolled Asthma.

Corren J, Parnes JR, Wang L, Mo M, Roseti SL, Griffiths JM, van der Merwe R.

N Engl J Med. 2017 Sep 7;377(10):936-946. doi: 10.1056/NEJMoa1704064.

2.

Effects of an anti-TSLP antibody on allergen-induced asthmatic responses.

Gauvreau GM, O'Byrne PM, Boulet LP, Wang Y, Cockcroft D, Bigler J, FitzGerald JM, Boedigheimer M, Davis BE, Dias C, Gorski KS, Smith L, Bautista E, Comeau MR, Leigh R, Parnes JR.

N Engl J Med. 2014 May 29;370(22):2102-10. doi: 10.1056/NEJMoa1402895. Epub 2014 May 20.

3.

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation.

Oliveira MI, Gonçalves CM, Pinto M, Fabre S, Santos AM, Lee SF, Castro MA, Nunes RJ, Barbosa RR, Parnes JR, Yu C, Davis SJ, Moreira A, Bismuth G, Carmo AM.

Eur J Immunol. 2012 Jan;42(1):195-205. doi: 10.1002/eji.201040528. Epub 2011 Nov 28.

4.

Modulation of peripheral B cell tolerance by CD72 in a murine model.

Li DH, Winslow MM, Cao TM, Chen AH, Davis CR, Mellins ED, Utz PJ, Crabtree GR, Parnes JR.

Arthritis Rheum. 2008 Oct;58(10):3192-204. doi: 10.1002/art.23812.

5.

Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse.

Castro MA, Oliveira MI, Nunes RJ, Fabre S, Barbosa R, Peixoto A, Brown MH, Parnes JR, Bismuth G, Moreira A, Rocha B, Carmo AM.

J Immunol. 2007 Apr 1;178(7):4351-61.

6.

A unique CD72 epitope suggests a potential interaction with Fc gamma RII/CD32 on B lineage lymphocytes.

Yamashita Y, Phee H, Tudor KS, Rossi MI, Parnes JR, Coggeshall KM, Kincade PW.

Hybridoma (Larchmt). 2006 Jun;25(3):107-14.

PMID:
16796456
7.

Medicine on a need-to-know basis.

Busch R, Byrne B, Gandrud L, Sears D, Meyer E, Kattah M, Kurihara C, Haertel E, Parnes JR, Mellins ED.

Nat Immunol. 2006 Jun;7(6):543-7.

PMID:
16715061
8.

CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes.

Li DH, Tung JW, Tarner IH, Snow AL, Yukinari T, Ngernmaneepothong R, Martinez OM, Parnes JR.

J Immunol. 2006 May 1;176(9):5321-8.

9.

Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells.

Zimmerman AW, Joosten B, Torensma R, Parnes JR, van Leeuwen FN, Figdor CG.

Blood. 2006 Apr 15;107(8):3212-20. Epub 2005 Dec 13.

10.

Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.

Kumanogoh A, Shikina T, Watanabe C, Takegahara N, Suzuki K, Yamamoto M, Takamatsu H, Prasad DV, Mizui M, Toyofuku T, Tamura M, Watanabe D, Parnes JR, Kikutani H.

Int Immunol. 2005 Oct;17(10):1277-82. Epub 2005 Aug 19.

PMID:
16113236
11.
12.

Dual regulation of BCR-mediated growth inhibition signaling by CD72.

Baba T, Fusaki N, Aoyama A, Li DH, Okamura RM, Parnes JR, Hozumi N.

Eur J Immunol. 2005 May;35(5):1634-42.

13.

Woodchuck interleukin-6 gene: structure, characterization, and biologic activity.

Li DH, Kumanogoh A, Cao TM, Parnes JR, Cullen JM.

Gene. 2004 Nov 10;342(1):157-64.

PMID:
15527975
14.

OX52 is the rat homologue of CD6: evidence for an effector function in the regulation of CD5 phosphorylation.

Castro MA, Nunes RJ, Oliveira MI, Tavares PA, Simões C, Parnes JR, Moreira A, Carmo AM.

J Leukoc Biol. 2003 Jan;73(1):183-90.

PMID:
12525577
15.

CD6: expression during development, apoptosis and selection of human and mouse thymocytes.

Singer NG, Fox DA, Haqqi TM, Beretta L, Endres JS, Prohaska S, Parnes JR, Bromberg J, Sramkoski RM.

Int Immunol. 2002 Jun;14(6):585-97.

PMID:
12039910
16.

The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice.

Shi W, Kumanogoh A, Watanabe C, Uchida J, Wang X, Yasui T, Yukawa K, Ikawa M, Okabe M, Parnes JR, Yoshida K, Kikutani H.

Immunity. 2000 Nov;13(5):633-42.

17.

Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling.

Kumanogoh A, Watanabe C, Lee I, Wang X, Shi W, Araki H, Hirata H, Iwahori K, Uchida J, Yasui T, Matsumoto M, Yoshida K, Yakura H, Pan C, Parnes JR, Kikutani H.

Immunity. 2000 Nov;13(5):621-31.

18.

CD72, a negative regulator of B-cell responsiveness.

Parnes JR, Pan C.

Immunol Rev. 2000 Aug;176:75-85. Review.

PMID:
11043769
19.
20.

Regulation of mouse CD72 gene expression during B lymphocyte development.

Ying H, Healy JI, Goodnow CC, Parnes JR.

J Immunol. 1998 Nov 1;161(9):4760-7.

21.
22.
23.
24.

The level of CD4 surface protein influences T cell selection in the thymus.

Frank GD, Parnes JR.

J Immunol. 1998 Jan 15;160(2):634-42.

25.

PU.1/Spi-1 is essential for the B cell-specific activity of the mouse CD72 promoter.

Ying H, Chang JF, Parnes JR.

J Immunol. 1998 Mar 1;160(5):2287-96.

26.

The Lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production.

Lewis LA, Chung CD, Chen J, Parnes JR, Moran M, Patel VP, Miceli MC.

J Immunol. 1997 Sep 1;159(5):2292-300.

PMID:
9278318
27.

Specific demethylation of the CD4 gene during CD4 T lymphocyte differentiation.

Tutt Landolfi MM, Scollay R, Parnes JR.

Mol Immunol. 1997 Jan;34(1):53-61.

PMID:
9182876
28.

Allele-specific expression of the mouse B-cell surface protein CD72 on T cells.

Robinson WH, Landolfi MM, Parnes JR.

Immunogenetics. 1997;45(3):195-200.

PMID:
8995186
29.

Molecular linkage of the mouse CD5 and CD6 genes.

Lecomte O, Bock JB, Birren BW, Vollrath D, Parnes JR.

Immunogenetics. 1996;44(5):385-90. No abstract available.

PMID:
8781125
30.

Chromosomal mapping of the second human CD8B gene locus.

Zhang XL, Heng HH, Yang Y, Tsui LC, Parnes JR, Chamberlain JW.

Immunogenetics. 1996;43(4):220-6. No abstract available.

PMID:
8575821
31.

Identification of a mouse protein homologous to the human CD6 T cell surface protein and sequence of the corresponding cDNA.

Robinson WH, Prohaska SS, Santoro JC, Robinson HL, Parnes JR.

J Immunol. 1995 Nov 15;155(10):4739-48.

PMID:
7594475
32.

Human CD6 possesses a large, alternatively spliced cytoplasmic domain.

Robinson WH, Neuman de Vegvar HE, Prohaska SS, Rhee JW, Parnes JR.

Eur J Immunol. 1995 Oct;25(10):2765-9.

PMID:
7589069
33.

Structure of the mouse CD72 (Lyb-2) gene and its alternatively spliced transcripts.

Ying H, Nakayama E, Robinson WH, Parnes JR.

J Immunol. 1995 Aug 1;155(3):1637. No abstract available.

PMID:
7636222
34.

Structure of the mouse CD72 (Lyb-2) gene and its alternatively spliced transcripts.

Ying H, Nakayama E, Robinson WH, Parnes JR.

J Immunol. 1995 Mar 15;154(6):2743-52. Erratum in: J Immunol. 1995 Aug 1;155(3):1637.

PMID:
7876545
35.
36.

Isolation of P1 bacteriophage clones containing large contiguous segments of the human and mouse loci for the T-cell coreceptor molecule CD8.

Zhang XL, Lee KL, Heng HH, Tsui LC, Parnes JR, Shepherd NS, Chamberlain JW.

Genet Anal Tech Appl. 1994;11(5-6):129-39.

PMID:
7710778
37.

Biochemical identity of the mouse Ly-19.2 and Ly-32.2 alloantigens with the B cell differentiation antigen Lyb-2/CD72.

Robinson WH, Landolfi MM, Schäfer H, Parnes JR.

J Immunol. 1993 Nov 1;151(9):4764-72.

PMID:
8409435
38.

CD2-CD4-CD8- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2+CD4+CD8+ thymic precursor.

Landolfi MM, Van Houten N, Russell JQ, Scollay R, Parnes JR, Budd RC.

J Immunol. 1993 Jul 15;151(2):1086-96.

PMID:
7687614
39.

Positive-negative selection gene targeting with the diphtheria toxin A-chain gene in mouse embryonic stem cells.

McCarrick JW 3rd, Parnes JR, Seong RH, Solter D, Knowles BB.

Transgenic Res. 1993 Jul;2(4):183-90.

PMID:
8364601
40.

The CD8 alpha locus is located on the telomere side of the immunoglobulin kappa locus at a distance of 2 Mb.

Weichhold GM, Huber C, Parnes JR, Zachau HG.

Genomics. 1993 May;16(2):512-4.

PMID:
8314589
41.

Role of CD4 and CD8 in T cell activation and differentiation.

Miceli MC, Parnes JR.

Adv Immunol. 1993;53:59-122. Review. No abstract available.

PMID:
8512039
42.

Human Lyb-2 homolog CD72 is a marker for progenitor B-cell leukemias.

Schwarting R, Castello R, Moldenhauer G, Pezzutto A, von Hoegen I, Ludwig WD, Parnes JR, Dörken B.

Am J Hematol. 1992 Nov;41(3):151-8.

PMID:
1384316
43.

Extensive polymorphism in the extracellular domain of the mouse B cell differentiation antigen Lyb-2/CD72.

Robinson WH, Ying H, Miceli MC, Parnes JR.

J Immunol. 1992 Aug 1;149(3):880-6.

PMID:
1634777
44.

An immunological role for the CD8 beta-chain.

Wheeler CJ, von Hoegen P, Parnes JR.

Nature. 1992 May 21;357(6375):247-9.

PMID:
1534146
45.

The T/B cell antigen, CD5, and the B-cell surface protein, CD72, form a pair of interacting receptors.

Van de Velde H, Von Hoegen I, Luo W, Parnes JR, Thielemans K.

Ann N Y Acad Sci. 1992 May 4;651:443-52. No abstract available.

PMID:
1376061
46.
47.

Ly-1 (CD5), a membrane glycoprotein of mouse T lymphocytes and a subset of B cells, is a natural ligand of the B cell surface protein Lyb-2 (CD72).

Luo W, Van de Velde H, von Hoegen I, Parnes JR, Thielemans K.

J Immunol. 1992 Mar 15;148(6):1630-4.

PMID:
1371783
48.

Alteration of T cell lineage commitment by expression of a hybrid CD8/CD4 transgene.

Seong RH, Parnes JR.

Adv Exp Med Biol. 1992;323:79-87. No abstract available.

PMID:
1485567
49.

Polymorphic specificity of Q1/28, a monoclonal antibody that preferentially reacts with free class I heavy chains.

Benjamin RJ, Abrams JR, Parnes JR, Madrigal JA, Parham P.

Immunogenetics. 1992;37(1):73-6. No abstract available.

PMID:
1428015
50.

The B-cell surface protein CD72/Lyb-2 is the ligand for CD5.

Van de Velde H, von Hoegen I, Luo W, Parnes JR, Thielemans K.

Nature. 1991 Jun 20;351(6328):662-5.

PMID:
1711157

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