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Items: 20

1.

Early Notch Signals Induce a Pathogenic Molecular Signature during Priming of Alloantigen-Specific Conventional CD4+ T Cells in Graft-versus-Host Disease.

Chung J, Radojcic V, Perkey E, Parnell TJ, Niknafs Y, Jin X, Friedman A, Labrecque N, Blazar BR, Brennan TV, Siebel CW, Maillard I.

J Immunol. 2019 Jul 15;203(2):557-568. doi: 10.4049/jimmunol.1900192. Epub 2019 Jun 10.

PMID:
31182480
2.

Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism.

Geoghegan G, Simcox J, Seldin MM, Parnell TJ, Stubben C, Just S, Begaye L, Lusis AJ, Villanueva CJ.

Mol Metab. 2019 Jun;24:44-63. doi: 10.1016/j.molmet.2019.03.003. Epub 2019 Mar 14.

3.

Establishment and Maintenance of Chromatin Architecture Are Promoted Independently of Transcription by the Histone Chaperone FACT and H3-K56 Acetylation in Saccharomyces cerevisiae.

McCullough LL, Pham TH, Parnell TJ, Connell Z, Chandrasekharan MB, Stillman DJ, Formosa T.

Genetics. 2019 Mar;211(3):877-892. doi: 10.1534/genetics.118.301853. Epub 2019 Jan 24.

PMID:
30679261
4.

Histone Deacetylase Inhibition Has Targeted Clinical Benefit in ARID1A-Mutated Advanced Urothelial Carcinoma.

Gupta S, Albertson DJ, Parnell TJ, Butterfield A, Weston A, Pappas LM, Dalley B, O'Shea JM, Lowrance WT, Cairns BR, Schiffman JD, Sharma S.

Mol Cancer Ther. 2019 Jan;18(1):185-195. doi: 10.1158/1535-7163.MCT-17-0957. Epub 2018 Oct 9.

PMID:
30301863
5.

Comprehensive Genomic Sequencing of Urothelial Tumors Identifies Rare SMARCB1 (INI-1)-Deficient Carcinomas of the Urinary System.

Gupta S, Albertson D, Gaston D, Heilbrun ME, Agarwal N, Boucher K, Parnell TJ, Liu T, Morgans A, Madison R, Gowen K, Miller VA, Ross JS, Ali SM, Millis SZ.

Clin Genitourin Cancer. 2018 Apr;16(2):e373-e382. doi: 10.1016/j.clgc.2017.09.001. Epub 2017 Sep 7.

PMID:
28974397
6.

A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.

Sdano MA, Fulcher JM, Palani S, Chandrasekharan MB, Parnell TJ, Whitby FG, Formosa T, Hill CP.

Elife. 2017 Aug 16;6. pii: e28723. doi: 10.7554/eLife.28723.

7.

Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription.

Ramakrishnan S, Pokhrel S, Palani S, Pflueger C, Parnell TJ, Cairns BR, Bhaskara S, Chandrasekharan MB.

Nat Commun. 2016 Jun 21;7:11949. doi: 10.1038/ncomms11949.

8.

The Plasma Membrane Protein Nce102 Implicated in Eisosome Formation Rescues a Heme Defect in Mitochondria.

Kim HJ, Jeong MY, Parnell TJ, Babst M, Phillips JD, Winge DR.

J Biol Chem. 2016 Aug 12;291(33):17417-26. doi: 10.1074/jbc.M116.727743. Epub 2016 Jun 17.

9.

Regulation of DNA Translocation Efficiency within the Chromatin Remodeler RSC/Sth1 Potentiates Nucleosome Sliding and Ejection.

Clapier CR, Kasten MM, Parnell TJ, Viswanathan R, Szerlong H, Sirinakis G, Zhang Y, Cairns BR.

Mol Cell. 2016 May 5;62(3):453-461. doi: 10.1016/j.molcel.2016.03.032.

10.

Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination.

Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB.

J Biol Chem. 2015 Nov 27;290(48):28760-77. doi: 10.1074/jbc.M115.693085. Epub 2015 Oct 8.

11.

The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism.

Parnell TJ, Schlichter A, Wilson BG, Cairns BR.

Elife. 2015 Mar 30;4:e06073. doi: 10.7554/eLife.06073.

12.

Reprogramming the maternal zebrafish genome after fertilization to match the paternal methylation pattern.

Potok ME, Nix DA, Parnell TJ, Cairns BR.

Cell. 2013 May 9;153(4):759-72. doi: 10.1016/j.cell.2013.04.030.

13.

Dynamic transcriptome of Schizosaccharomyces pombe shown by RNA-DNA hybrid mapping.

Dutrow N, Nix DA, Holt D, Milash B, Dalley B, Westbroek E, Parnell TJ, Cairns BR.

Nat Genet. 2008 Aug;40(8):977-86. doi: 10.1038/ng.196. Epub 2008 Jul 20.

14.

Investigation of the properties of non-gypsy suppressor of hairy-wing-binding sites.

Kuhn-Parnell EJ, Helou C, Marion DJ, Gilmore BL, Parnell TJ, Wold MS, Geyer PK.

Genetics. 2008 Jul;179(3):1263-73. doi: 10.1534/genetics.108.087254. Epub 2008 Jun 18.

15.

RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes.

Parnell TJ, Huff JT, Cairns BR.

EMBO J. 2008 Jan 9;27(1):100-10. Epub 2007 Dec 6.

16.

Identification of genomic sites that bind the Drosophila suppressor of Hairy-wing insulator protein.

Parnell TJ, Kuhn EJ, Gilmore BL, Helou C, Wold MS, Geyer PK.

Mol Cell Biol. 2006 Aug;26(16):5983-93.

17.

An endogenous suppressor of hairy-wing insulator separates regulatory domains in Drosophila.

Parnell TJ, Viering MM, Skjesol A, Helou C, Kuhn EJ, Geyer PK.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13436-41. Epub 2003 Nov 3.

18.

Long-range repression by multiple polycomb group (PcG) proteins targeted by fusion to a defined DNA-binding domain in Drosophila.

Roseman RR, Morgan K, Mallin DR, Roberson R, Parnell TJ, Bornemann DJ, Simon JA, Geyer PK.

Genetics. 2001 May;158(1):291-307.

19.
20.

Association of MSX1 and TGFB3 with nonsyndromic clefting in humans.

Lidral AC, Romitti PA, Basart AM, Doetschman T, Leysens NJ, Daack-Hirsch S, Semina EV, Johnson LR, Machida J, Burds A, Parnell TJ, Rubenstein JL, Murray JC.

Am J Hum Genet. 1998 Aug;63(2):557-68.

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