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mRNA Expression and Activity of Nucleoside Transporters in Human Hepatoma HepaRG Cells.

Mayati A, Moreau A, Jouan E, Febvre-James M, Denizot C, Parmentier Y, Fardel O.

Pharmaceutics. 2018 Nov 21;10(4). pii: E246. doi: 10.3390/pharmaceutics10040246.


LC-MS/MS-based quantification of efflux transporter proteins at the BBB.

Gomez-Zepeda D, Taghi M, Smirnova M, Sergent P, Liu WQ, Chhuon C, Vidal M, Picard M, Thioulouse E, Broutin I, Guerrera IC, Scherrmann JM, Parmentier Y, Decleves X, Menet MC.

J Pharm Biomed Anal. 2019 Feb 5;164:496-508. doi: 10.1016/j.jpba.2018.11.013. Epub 2018 Nov 8.


Functional polarization of human hepatoma HepaRG cells in response to forskolin.

Mayati A, Moreau A, Le Vée M, Bruyère A, Jouan E, Denizot C, Parmentier Y, Fardel O.

Sci Rep. 2018 Oct 31;8(1):16115. doi: 10.1038/s41598-018-34421-8.


Evaluation of Drug Biliary Excretion Using Sandwich-Cultured Human Hepatocytes.

Fardel O, Moreau A, Le Vée M, Denizot C, Parmentier Y.

Eur J Drug Metab Pharmacokinet. 2019 Feb;44(1):13-30. doi: 10.1007/s13318-018-0502-x. Review.


New insights in the in vitro characterisation and molecular modelling of the P-glycoprotein inhibitory promiscuity.

Bocci G, Moreau A, Vayer P, Denizot C, Fardel O, Parmentier Y.

Eur J Pharm Sci. 2018 Aug 30;121:85-94. doi: 10.1016/j.ejps.2018.04.039. Epub 2018 Apr 28.


Direct and quantitative evaluation of the major human CYP contribution (fmCYP) to drug clearance using the in vitro Silensomes™ model.

Parmentier Y, Pothier C, Hewitt N, Vincent L, Caradec F, Liu J, Lin F, Trancart MM, Guillet F, Bouaita B, Chesne C, Walther B.

Xenobiotica. 2019 Jan;49(1):22-35. doi: 10.1080/00498254.2017.1422156. Epub 2018 Jan 10.


β2-adrenergic receptor-mediated in vitro regulation of human hepatic drug transporter expression by epinephrine.

Mayati A, Moreau A, Denizot C, Stieger B, Parmentier Y, Fardel O.

Eur J Pharm Sci. 2017 Aug 30;106:302-312. doi: 10.1016/j.ejps.2017.06.010. Epub 2017 Jun 8.


Targeted unlabeled multiple reaction monitoring analysis of cell markers for the study of sample heterogeneity in isolated rat brain cortical microvessels.

Gomez-Zepeda D, Chaves C, Taghi M, Sergent P, Liu WQ, Chhuon C, Vidal M, Picard M, Thioulouse E, Broutin I, Guerrera IC, Scherrmann JM, Parmentier Y, Decleves X, Menet MC.

J Neurochem. 2017 Aug;142(4):597-609. doi: 10.1111/jnc.14095. Epub 2017 Jul 11.


Prediction of renal transporter-mediated drug-drug interactions for a drug which is an OAT substrate and inhibitor using PBPK modelling.

Ball K, Jamier T, Parmentier Y, Denizot C, Mallier A, Chenel M.

Eur J Pharm Sci. 2017 Aug 30;106:122-132. doi: 10.1016/j.ejps.2017.05.055. Epub 2017 May 25.


Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression.

Mayati A, Moreau A, Le Vée M, Stieger B, Denizot C, Parmentier Y, Fardel O.

Int J Mol Sci. 2017 Apr 4;18(4). pii: E764. doi: 10.3390/ijms18040764. Review.


Effect of Gevokizumab on Interleukin-1β-Mediated Cytochrome P450 3A4 and Drug Transporter Repression in Cultured Human Hepatocytes.

Moreau A, Le Vée M, Jouan E, Denizot C, Parmentier Y, Fardel O.

Eur J Drug Metab Pharmacokinet. 2017 Oct;42(5):871-878. doi: 10.1007/s13318-017-0406-1.


Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin.

Chedik L, Bruyere A, Le Vee M, Stieger B, Denizot C, Parmentier Y, Potin S, Fardel O.

PLoS One. 2017 Jan 18;12(1):e0169480. doi: 10.1371/journal.pone.0169480. eCollection 2017.


Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells.

Jouan E, Le Vée M, Denizot C, Parmentier Y, Fardel O.

Pharmaceutics. 2016 Dec 28;9(1). pii: E3. doi: 10.3390/pharmaceutics9010003.


Inhibition of SLC drug transporter activities by environmental bisphenols.

Bruyere A, Hubert C, Le Vee M, Chedik L, Sayyed K, Stieger B, Denizot C, Parmentier Y, Fardel O.

Toxicol In Vitro. 2017 Apr;40:34-44. doi: 10.1016/j.tiv.2016.12.009. Epub 2016 Dec 15.


Direct and quantitative evaluation of the human CYP3A4 contribution (fm) to drug clearance using the in vitro SILENSOMES model.

Parmentier Y, Pothier C, Delmas A, Caradec F, Trancart MM, Guillet F, Bouaita B, Chesne C, Brian Houston J, Walther B.

Xenobiotica. 2017 Jul;47(7):562-575. doi: 10.1080/00498254.2016.1208854. Epub 2016 Aug 3.


Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate.

Sayyed K, Vee ML, Abdel-Razzak Z, Jouan E, Stieger B, Denizot C, Parmentier Y, Fardel O.

Toxicology. 2016 Jul 1;363-364:58-71. doi: 10.1016/j.tox.2016.07.011. Epub 2016 Jul 19.


Evaluation of P-Glycoprotein Inhibitory Potential Using a Rhodamine 123 Accumulation Assay.

Jouan E, Le Vée M, Mayati A, Denizot C, Parmentier Y, Fardel O.

Pharmaceutics. 2016 Apr 12;8(2). pii: E12. doi: 10.3390/pharmaceutics8020012.


Protein Kinase C-Independent Inhibition of Organic Cation Transporter 1 Activity by the Bisindolylmaleimide Ro 31-8220.

Mayati A, Bruyere A, Moreau A, Jouan E, Denizot C, Parmentier Y, Fardel O.

PLoS One. 2015 Dec 10;10(12):e0144667. doi: 10.1371/journal.pone.0144667. eCollection 2015.


Protein kinase C-dependent regulation of human hepatic drug transporter expression.

Mayati A, Le Vee M, Moreau A, Jouan E, Bucher S, Stieger B, Denizot C, Parmentier Y, Fardel O.

Biochem Pharmacol. 2015 Dec 15;98(4):703-17. doi: 10.1016/j.bcp.2015.10.007. Epub 2015 Oct 14.


Analysis of Sinusoidal Drug Uptake Transporter Activities in Primary Human Hepatocytes.

Le Vée M, Jouan E, Denizot C, Parmentier Y, Fardel O.

Methods Mol Biol. 2015;1250:287-302. doi: 10.1007/978-1-4939-2074-7_21.


Pharmacophore-based discovery of inhibitors of a novel drug/proton antiporter in human brain endothelial hCMEC/D3 cell line.

Chapy H, Goracci L, Vayer P, Parmentier Y, Carrupt PA, Declèves X, Scherrmann JM, Cisternino S, Cruciani G.

Br J Pharmacol. 2015 Oct;172(20):4888-904. doi: 10.1111/bph.13258. Epub 2015 Oct 13.


Nature and uses of fluorescent dyes for drug transporter studies.

Fardel O, Le Vee M, Jouan E, Denizot C, Parmentier Y.

Expert Opin Drug Metab Toxicol. 2015;11(8):1233-51. doi: 10.1517/17425255.2015.1053462. Epub 2015 Jun 7. Review.


Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes.

Noel G, Le Vee M, Moreau A, Stieger B, Parmentier Y, Fardel O.

Eur J Pharm Sci. 2013 Apr 11;49(1):39-50. doi: 10.1016/j.ejps.2013.01.013. Epub 2013 Feb 6.


Trends in hip fracture incidence and in the prescription of antiosteoporosis medications during the same time period in Belgium (2000-2007).

Hiligsmann M, Bruyère O, Roberfroid D, Dubois C, Parmentier Y, Carton J, Detilleux J, Gillet P, Reginster JY.

Arthritis Care Res (Hoboken). 2012 May;64(5):744-50. doi: 10.1002/acr.21607.


MATH/BTB CRL3 receptors target the homeodomain-leucine zipper ATHB6 to modulate abscisic acid signaling.

Lechner E, Leonhardt N, Eisler H, Parmentier Y, Alioua M, Jacquet H, Leung J, Genschik P.

Dev Cell. 2011 Dec 13;21(6):1116-28. doi: 10.1016/j.devcel.2011.10.018.


Drug transporter expression in human macrophages.

Moreau A, Le Vee M, Jouan E, Parmentier Y, Fardel O.

Fundam Clin Pharmacol. 2011 Dec;25(6):743-52. doi: 10.1111/j.1472-8206.2010.00913.x. Epub 2011 Jan 7.


Metabonomic studies on human hepatocyte in primary culture.

Croixmarie V, Umbdenstock T, Cloarec O, Moreau A, Pascussi JM, Parmentier Y, Boursier-Neyret C, Walther B.

Methods Mol Biol. 2010;640:355-74. doi: 10.1007/978-1-60761-688-7_19.


Hospital-acquired, laboratory-confirmed bloodstream infections: linking national surveillance data to clinical and financial hospital data to estimate increased length of stay and healthcare costs.

Vrijens F, Hulstaert F, Van de Sande S, Devriese S, Morales I, Parmentier Y.

J Hosp Infect. 2010 Jul;75(3):158-62. doi: 10.1016/j.jhin.2009.12.006. Epub 2010 Apr 10.


Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).

Breuker C, Moreau A, Lakhal L, Tamasi V, Parmentier Y, Meyer U, Maurel P, Lumbroso S, Vilarem MJ, Pascussi JM.

Endocrinology. 2010 Apr;151(4):1653-61. doi: 10.1210/en.2009-1435. Epub 2010 Feb 25.


A novel pregnane X receptor and S14-mediated lipogenic pathway in human hepatocyte.

Moreau A, Téruel C, Beylot M, Albalea V, Tamasi V, Umbdenstock T, Parmentier Y, Sa-Cunha A, Suc B, Fabre JM, Navarro F, Ramos J, Meyer U, Maurel P, Vilarem MJ, Pascussi JM.

Hepatology. 2009 Jun;49(6):2068-79. doi: 10.1002/hep.22907.


The APC/C E3 ligase remains active in most post-mitotic Arabidopsis cells and is required for proper vasculature development and organization.

Marrocco K, Thomann A, Parmentier Y, Genschik P, Criqui MC.

Development. 2009 May;136(9):1475-85. doi: 10.1242/dev.035535. Epub 2009 Mar 31.


Development of an optimized procedure for the preparation of rat intestinal microsomes: comparison of hepatic and intestinal microsomal cytochrome P450 enzyme activities in two rat strains.

Bruyère A, Declevès X, Bouzom F, Proust L, Martinet M, Walther B, Parmentier Y.

Xenobiotica. 2009 Jan;39(1):22-32. doi: 10.1080/00498250802517714 .


Arabidopsis CULLIN3 genes regulate primary root growth and patterning by ethylene-dependent and -independent mechanisms.

Thomann A, Lechner E, Hansen M, Dumbliauskas E, Parmentier Y, Kieber J, Scheres B, Genschik P.

PLoS Genet. 2009 Jan;5(1):e1000328. doi: 10.1371/journal.pgen.1000328. Epub 2009 Jan 9.


More is not better in the early care of acute myocardial infarction: a prospective cohort analysis on administrative databases.

Van Brabandt H, Camberlin C, Vrijens F, Parmentier Y, Ramaekers D, Bonneux L.

Eur Heart J. 2006 Nov;27(22):2649-54. Epub 2006 Aug 4.


Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes.

Jigorel E, Le Vee M, Boursier-Neyret C, Parmentier Y, Fardel O.

Drug Metab Dispos. 2006 Oct;34(10):1756-63. Epub 2006 Jul 12.


Molecular and functional characterization of Arabidopsis Cullin 3A.

Dieterle M, Thomann A, Renou JP, Parmentier Y, Cognat V, Lemonnier G, Müller R, Shen WH, Kretsch T, Genschik P.

Plant J. 2005 Feb;41(3):386-99.


Liquid chromatography-accurate radioisotope counting and microplate scintillation counter technologies in drug metabolism studies.

Nassar AE, Parmentier Y, Martinet M, Lee DY.

J Chromatogr Sci. 2004 Aug;42(7):348-53.


EIN3-dependent regulation of plant ethylene hormone signaling by two arabidopsis F box proteins: EBF1 and EBF2.

Potuschak T, Lechner E, Parmentier Y, Yanagisawa S, Grava S, Koncz C, Genschik P.

Cell. 2003 Dec 12;115(6):679-89.


The Arabidopsis anaphase-promoting complex or cyclosome: molecular and genetic characterization of the APC2 subunit.

Capron A, Serralbo O, Fülöp K, Frugier F, Parmentier Y, Dong A, Lecureuil A, Guerche P, Kondorosi E, Scheres B, Genschik P.

Plant Cell. 2003 Oct;15(10):2370-82. Epub 2003 Sep 24. Erratum in: Plant Cell. 2019 Jun;31(6):1386-1387.


National survey on cholecystectomy related bile duct injury--public health and financial aspects in Belgian hospitals--1997.

Van de Sande S, Bossens M, Parmentier Y, Gigot JF.

Acta Chir Belg. 2003 Apr;103(2):168-80.


Molecular characterization of plant ubiquitin-conjugating enzymes belonging to the UbcP4/E2-C/UBCx/UbcH10 gene family.

Criqui MC, de Almeida Engler J, Camasses A, Capron A, Parmentier Y, Inzé D, Genschik P.

Plant Physiol. 2002 Nov;130(3):1230-40.


The AtRbx1 protein is part of plant SCF complexes, and its down-regulation causes severe growth and developmental defects.

Lechner E, Xie D, Grava S, Pigaglio E, Planchais S, Murray JA, Parmentier Y, Mutterer J, Dubreucq B, Shen WH, Genschik P.

J Biol Chem. 2002 Dec 20;277(51):50069-80. Epub 2002 Oct 14.


Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis.

Shen WH, Parmentier Y, Hellmann H, Lechner E, Dong A, Masson J, Granier F, Lepiniec L, Estelle M, Genschik P.

Mol Biol Cell. 2002 Jun;13(6):1916-28.


Sub-cellular localisation of GFP-tagged tobacco mitotic cyclins during the cell cycle and after spindle checkpoint activation.

Criqui MC, Weingartner M, Capron A, Parmentier Y, Shen WH, Heberle-Bors E, Bögre L, Genschik P.

Plant J. 2001 Dec;28(5):569-81.


Effects of the polyubiquitin gene Ubi. U4 leader intron and first ubiquitin monomer on reporter gene expression in Nicotiana tabacum.

Plesse B, Criqui MC, Durr A, Parmentier Y, Fleck J, Genschik P.

Plant Mol Biol. 2001 Apr;45(6):655-67.


Cell cycle-dependent proteolysis and ectopic overexpression of cyclin B1 in tobacco BY2 cells.

Criqui MC, Parmentier Y, Derevier A, Shen WH, Dong A, Genschik P.

Plant J. 2000 Dec;24(6):763-73.


A YAC contig map of Arabidopsis thaliana chromosome 3.

Camilleri C, Lafleuriel J, Macadré C, Varoquaux F, Parmentier Y, Picard G, Caboche M, Bouchez D.

Plant J. 1998 Jun;14(5):633-42.


The 20S proteasome gene family in Arabidopsis thaliana.

Parmentier Y, Bouchez D, Fleck J, Genschik P.

FEBS Lett. 1997 Oct 27;416(3):281-5.


Characterization of a tobacco extensin gene and regulation of its gene family in healthy plants and under various stress conditions.

Hirsinger C, Parmentier Y, Durr A, Fleck J, Jamet E.

Plant Mol Biol. 1997 Jan;33(2):279-89.


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