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Addition of docetaxel to hormonal therapy in low- and high-burden metastatic hormone sensitive prostate cancer: long-term survival results from the STAMPEDE trial.

Clarke NW, Ali A, Ingleby FC, Hoyle A, Amos CL, Attard G, Brawley CD, Calvert J, Chowdhury S, Cook A, Cross W, Dearnaley DP, Douis H, Gilbert D, Gillessen S, Jones RJ, Langley RE, MacNair A, Malik Z, Mason MD, Matheson D, Millman R, Parker CC, Ritchie AWS, Rush H, Russell JM, Brown J, Beesley S, Birtle A, Capaldi L, Gale J, Gibbs S, Lydon A, Nikapota A, Omlin A, O'Sullivan JM, Parikh O, Protheroe A, Rudman S, Srihari NN, Simms M, Tanguay JS, Tolan S, Wagstaff J, Wallace J, Wylie J, Zarkar A, Sydes MR, Parmar MKB, James ND.

Ann Oncol. 2019 Sep 27. pii: mdz396. doi: 10.1093/annonc/mdz396. [Epub ahead of print]


hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease.

Adler AF, Cardoso T, Nolbrant S, Mattsson B, Hoban DB, Jarl U, Wahlestedt JN, Grealish S, Björklund A, Parmar M.

Cell Rep. 2019 Sep 24;28(13):3462-3473.e5. doi: 10.1016/j.celrep.2019.08.058.


Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons.

Birtele M, Sharma Y, Kidnapillai S, Lau S, Stoker TB, Barker RA, Rylander Ottosson D, Drouin-Ouellet J, Parmar M.

FEBS Lett. 2019 Sep 19. doi: 10.1002/1873-3468.13612. [Epub ahead of print]


Evaluation of left ventricular mechanical dyssynchrony with phase analysis in end-stage renal disease patients with normal gated SPECT-MPI.

Malik D, Mittal BR, Sood A, Sharma A, Parmar M, Kaur K, Bahl A.

World J Nucl Med. 2019 Jul-Sep;18(3):238-243. doi: 10.4103/wjnm.WJNM_49_18.


Radiotherapy for metastatic prostate cancer-Authors' reply.

Parker CC, James ND, Brawley CD, Clarke NW, Parmar MKB.

Lancet. 2019 Sep 7;394(10201):830. doi: 10.1016/S0140-6736(19)31829-X. No abstract available.


Abiraterone in "High-" and "Low-risk" Metastatic Hormone-sensitive Prostate Cancer.

Hoyle AP, Ali A, James ND, Cook A, Parker CC, de Bono JS, Attard G, Chowdhury S, Cross WR, Dearnaley DP, Brawley CD, Gilson C, Ingleby F, Gillessen S, Aebersold DM, Jones RJ, Matheson D, Millman R, Mason MD, Ritchie AWS, Russell M, Douis H, Parmar MKB, Sydes MR, Clarke NW; STAMPEDE Investigators.

Eur Urol. 2019 Aug 22. pii: S0302-2838(19)30620-7. doi: 10.1016/j.eururo.2019.08.006. [Epub ahead of print]


Reversible perfusion defect in hypertrophied papillary muscle on myocardial perfusion imaging: The 'filled doughnut sign'.

Vadi SK, Panda P, Sood A, Bahl A, Debi U, Parmar M, Yaser M, Mittal BR.

J Nucl Cardiol. 2019 Aug 9. doi: 10.1007/s12350-019-01848-z. [Epub ahead of print] No abstract available.


Recurrent reversible neurologic deficits during hemodialysis.

Parmar MS.

Semin Dial. 2019 Aug 1. doi: 10.1111/sdi.12835. [Epub ahead of print]


Impact of retrospective data verification to prepare the ICON6 trial for use in a marketing authorization application.

Embleton-Thirsk A, Deane E, Townsend S, Farrelly L, Popoola B, Parker J, Rustin G, Sydes M, Parmar M, Ledermann J, Kaplan R.

Clin Trials. 2019 Oct;16(5):502-511. doi: 10.1177/1740774519862528. Epub 2019 Jul 26.


'I am on treatment since 5 months but I have not received any money': coverage, delays and implementation challenges of 'Direct Benefit Transfer' for tuberculosis patients - a mixed-methods study from South India.

Nirgude AS, Kumar AMV, Collins T, Naik PR, Parmar M, Tao L, Akshaya KM, Raghuveer P, Yatnatti SK, Nagendra N, Nagaraja SB, Habeena S, Mn B, Rao R, Shastri S.

Glob Health Action. 2019;12(1):1633725. doi: 10.1080/16549716.2019.1633725.


Advances in stem cell research and therapeutic development.

De Luca M, Aiuti A, Cossu G, Parmar M, Pellegrini G, Robey PG.

Nat Cell Biol. 2019 Jul;21(7):801-811. doi: 10.1038/s41556-019-0344-z. Epub 2019 Jun 17. Review.


Comments on design and monitoring of survival trials in complex scenarios.

Barthel FM, Babiker A, Royston P, Parmar MK.

Stat Med. 2019 Jun 30;38(14):2704. doi: 10.1002/sim.8087. No abstract available.


Clarification re naloxone administered to study subject versus other overdose victim in the N-ALIVE pilot randomized trial.

Parmar MKB, Strang J, Choo L, Meade AM, Bird SM.

Addiction. 2019 Jul;114(7):1325. doi: 10.1111/add.14284. No abstract available.


Addition of Docetaxel to First-line Long-term Hormone Therapy in Prostate Cancer (STAMPEDE): Modelling to Estimate Long-term Survival, Quality-adjusted Survival, and Cost-effectiveness.

Woods BS, Sideris E, Sydes MR, Gannon MR, Parmar MKB, Alzouebi M, Attard G, Birtle AJ, Brock S, Cathomas R, Chakraborti PR, Cook A, Cross WR, Dearnaley DP, Gale J, Gibbs S, Graham JD, Hughes R, Jones RJ, Laing R, Mason MD, Matheson D, McLaren DB, Millman R, O'Sullivan JM, Parikh O, Parker CC, Peedell C, Protheroe A, Ritchie AWS, Robinson A, Russell JM, Simms MS, Srihari NN, Srinivasan R, Staffurth JN, Sundar S, Thalmann GN, Tolan S, Tran ATH, Tsang D, Wagstaff J, James ND, Sculpher MJ.

Eur Urol Oncol. 2018 Dec;1(6):449-458. doi: 10.1016/j.euo.2018.06.004. Epub 2018 Sep 14.


SMA-PAGE: A new method to examine complexes of membrane proteins using SMALP nano-encapsulation and native gel electrophoresis.

Pollock NL, Rai M, Simon KS, Hesketh SJ, Teo ACK, Parmar M, Sridhar P, Collins R, Lee SC, Stroud ZN, Bakker SE, Muench SP, Barton CH, Hurlbut G, Roper DI, Smith CJI, Knowles TJ, Spickett CM, East JM, Postis VLG, Dafforn TR.

Biochim Biophys Acta Biomembr. 2019 Aug 1;1861(8):1437-1445. doi: 10.1016/j.bbamem.2019.05.011. Epub 2019 May 28.


De-indexed estimated glomerular filtration rates: A simple step towards improving accuracy of drug dosing of renally excreted medications in moderate to severe obesity.

Vlasschaert C, Thibodeau S, Parmar MS.

Nephrology (Carlton). 2019 May 30. doi: 10.1111/nep.13621. [Epub ahead of print]


This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols.

Schiavone F, Bathia R, Letchemanan K, Masters L, Amos C, Bara A, Brown L, Gilson C, Pugh C, Atako N, Hudson F, Parmar M, Langley R, Kaplan RS, Parker C, Attard G, Clarke NW, Gillessen S, James ND, Maughan T, Sydes MR; past and present members of the STAMPEDE and FOCUS4 Trial Management Group.

Trials. 2019 May 29;20(1):264. doi: 10.1186/s13063-019-3216-8.


Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons.

Hague D, Townsend S, Masters L, Rauchenberger M, Van Looy N, Diaz-Montana C, Gannon M, James N, Maughan T, Parmar MKB, Brown L, Sydes MR; STAMPEDE and FOCUS4 investigators.

Trials. 2019 May 29;20(1):294. doi: 10.1186/s13063-019-3322-7.


Mind the gap? The platform trial as a working environment.

Morrell L, Hordern J, Brown L, Sydes MR, Amos CL, Kaplan RS, Parmar MKB, Maughan TS.

Trials. 2019 May 29;20(1):297. doi: 10.1186/s13063-019-3377-5.


Association of use of proton pump inhibitors and H2 antagonists with stomach wall uptake in 99mTc-methoxy-isobutyl-isonitrile (MIBI) myocardial perfusion imaging.

Singh H, Mittal BR, Sood A, Bollampally N, Gorla AKR, Dasagrandhi V, Parmar M.

J Nucl Cardiol. 2019 May 13. doi: 10.1007/s12350-019-01733-9. [Epub ahead of print]


Innovation in haemodialysis: Thinking 'out-of-the-box'. Avoiding central venous catheter in a maintenance haemodialysis patient following fracture of the arteriovenous access arm.

Parmar MS.

Nephrology (Carlton). 2019 Aug;24(8):878-879. doi: 10.1111/nep.13585. Epub 2019 May 7. No abstract available.


Effect of roscovitine on developmental competence of small follicle-derived buffalo oocytes.

Pandey S, Somal A, Parmar MS, Gupta S, Bharti MK, Bhat IA, Indu B, Chandra V, Kumar GS, Sharma GT.

Indian J Med Res. 2018 Dec;148(Suppl):S140-S150. doi: 10.4103/ijmr.IJMR_2068_17.


Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform.

Stacey GN, Andrews PW, Barbaric I, Boiers C, Chandra A, Cossu G, Csontos L, Frith TJ, Halliwell JA, Hewitt Z, McCall M, Moore HD, Parmar M, Panico MB, Pisupati V, Shichkin VP, Stacey AR, Tedesco FS, Thompson O, Wagey R.

Regen Med. 2019 Mar;14(3):243-255. doi: 10.2217/rme-2019-0001. Epub 2019 Apr 2.


Combined test versus logrank/Cox test in 50 randomised trials.

Royston P, Choodari-Oskooei B, Parmar MKB, Rogers JK.

Trials. 2019 Mar 18;20(1):172. doi: 10.1186/s13063-019-3251-5.


N-TB: A mobile-based application to simplify nutritional assessment, counseling and care of patients with tuberculosis in India.

Bhargava A, Bhargava M, Pande T, Rao R, Parmar M.

Indian J Tuberc. 2019 Jan;66(1):193-196. doi: 10.1016/j.ijtb.2018.10.005. Epub 2018 Nov 7.


Prostate Radiotherapy for Metastatic Hormone-sensitive Prostate Cancer: A STOPCAP Systematic Review and Meta-analysis.

Burdett S, Boevé LM, Ingleby FC, Fisher DJ, Rydzewska LH, Vale CL, van Andel G, Clarke NW, Hulshof MC, James ND, Parker CC, Parmar MK, Sweeney CJ, Sydes MR, Tombal B, Verhagen PC, Tierney JF; STOPCAP M1 Radiotherapy Collaborators.

Eur Urol. 2019 Jul;76(1):115-124. doi: 10.1016/j.eururo.2019.02.003. Epub 2019 Feb 28.


Echocardiogram: The GPS to GPA's Heart (Granulomatosis with Polyangiitis).

Parmar MK, Alikhan M, Hsu VM, Borham A.

Case Rep Rheumatol. 2019 Jan 16;2019:7609386. doi: 10.1155/2019/7609386. eCollection 2019.


Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development.

Tiklová K, Björklund ÅK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmström F, Joodmardi E, Nilsson M, Parmar M, Perlmann T.

Nat Commun. 2019 Feb 4;10(1):581. doi: 10.1038/s41467-019-08453-1.


Effect of ursodeoxycholic acid in facilitating early hepatic clearance of radiotracer among patients undergoing 99mTc-sestamibi myocardial perfusion scintigraphy: A randomized double blind placebo controlled parallel trial.

Sood A, Singh D, Dutta U, Mittal BR, Parmar M, Kaur G, Kaur K.

J Nucl Cardiol. 2019 Jan 29. doi: 10.1007/s12350-019-01597-z. [Epub ahead of print]


Impact of hibernating and viable myocardium on improvement in perfusion and left ventricular ejection fraction after coronary artery bypass graft.

Arora Y, Singh RS, Sampath S, Sood A, Singh P, Singh H, Mishra AK, Parmar M.

Nucl Med Commun. 2019 Apr;40(4):325-332. doi: 10.1097/MNM.0000000000000976.


Assessing the impact of efficacy stopping rules on the error rates under the multi-arm multi-stage framework.

Blenkinsop A, Parmar MK, Choodari-Oskooei B.

Clin Trials. 2019 Apr;16(2):132-141. doi: 10.1177/1740774518823551. Epub 2019 Jan 16.


Nutritional assessment and counselling of tuberculosis patients at primary care in India: do we measure up?

Bhargava M, Bhargava A, Akshaya KM, Shastri SG, Bairy R, Parmar M, Sharath BN.

Int J Tuberc Lung Dis. 2019 Feb 1;23(2):147-150. doi: 10.5588/ijtld.18.0333. Epub 2019 Jan 8.


Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies.

Henchcliffe C, Parmar M.

J Parkinsons Dis. 2018;8(s1):S131-S137. doi: 10.3233/JPD-181488.


Flip-flop right ventricle myocardial perfusion on stress-rest 99mTc-MIBI myocardial perfusion scintigraphy: An indirect evidence for severe left ventricular coronary arterial disease?

Vadi SK, Mehrotra S, Sood A, Parmar M, Dasagrandhi V, Kaur K, Mittal BR.

J Nucl Cardiol. 2019 Jun;26(3):1033-1035. doi: 10.1007/s12350-018-01565-z. Epub 2018 Dec 13. No abstract available.


Tuberculosis infection control measures at health care facilities offering HIV and tuberculosis services in India: A baseline assessment.

Sachdeva KS, Deshmukh RD, Seguy NS, Nair SA, Rewari BB, Ramchandran R, Parmar M, Vohra V, Singh S, Ghedia M, Agarwal R, Shah AN, Balasubramanian D, Bamrotiya M, Sikhamani R, Gupta RS, Khaparde SD.

Indian J Tuberc. 2018 Oct;65(4):280-284. doi: 10.1016/j.ijtb.2018.04.004. Epub 2018 Apr 19.


Chronic morbidity and reported disability among older persons from the India Human Development Survey.

Parmar MC, Saikia N.

BMC Geriatr. 2018 Dec 7;18(1):299. doi: 10.1186/s12877-018-0979-9.


Stress-induced ischemia in the right ventricular myocardium on 99mTc-MIBI myocardial perfusion scintigraphy in a rare case of double-chambered right ventricle.

Vadi SK, Rajan P, Sood A, Rohit MK, Parmar M, Kaur K, Mittal BR.

J Nucl Cardiol. 2018 Nov 26. doi: 10.1007/s12350-018-01528-4. [Epub ahead of print] No abstract available.


Exploratory outcome analyses according to stage and/or residual disease in the ICON7 trial of carboplatin and paclitaxel with or without bevacizumab for newly diagnosed ovarian cancer.

González Martín A, Oza AM, Embleton AC, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, Bertrand MA, Beale P, Cervantes A, Kent E, Kaplan RS, Parmar MKB, Scotto N, Perren TJ; ICON7 investigators.

Gynecol Oncol. 2019 Jan;152(1):53-60. doi: 10.1016/j.ygyno.2018.08.036. Epub 2018 Nov 16.


Two Cases of 188Re Microspheres for Inoperable Hepatocellular Carcinoma.

Shukla J, Kalra N, Kumar R, Bhusari P, Chhabra A, Parmar M, Vatsa R, Singh H, Duseja A, Mittal BR.

Clin Nucl Med. 2019 Feb;44(2):e93-e95. doi: 10.1097/RLU.0000000000002373.


Neoadjuvant chemotherapy versus debulking surgery in advanced tubo-ovarian cancers: pooled analysis of individual patient data from the EORTC 55971 and CHORUS trials.

Vergote I, Coens C, Nankivell M, Kristensen GB, Parmar MKB, Ehlen T, Jayson GC, Johnson N, Swart AM, Verheijen R, McCluggage WG, Perren T, Panici PB, Kenter G, Casado A, Mendiola C, Stuart G, Reed NS, Kehoe S; EORTC; MRC CHORUS study investigators.

Lancet Oncol. 2018 Dec;19(12):1680-1687. doi: 10.1016/S1470-2045(18)30566-7. Epub 2018 Nov 6. Erratum in: Lancet Oncol. 2019 Jan;20(1):e10.


Tuberculosis preventive treatment: the next chapter of tuberculosis elimination in India.

Moonan PK, Nair SA, Agarwal R, Chadha VK, Dewan PK, Gupta UD, Ho CS, Holtz TH, Kumar AM, Kumar N, Kumar P, Maloney SA, Mase SR, Oeltmann JE, Paramasivan CN, Parmar MM, Rade KK, Ramachandran R, Rao R, Salhorta VS, Sarin R, Sarin S, Sachdeva KS, Selvaraju S, Singla R, Surie D, Tonsing J, Tripathy SP, Khaparde SD.

BMJ Glob Health. 2018 Oct 8;3(5):e001135. doi: 10.1136/bmjgh-2018-001135. eCollection 2018.


Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.

Parker CC, James ND, Brawley CD, Clarke NW, Hoyle AP, Ali A, Ritchie AWS, Attard G, Chowdhury S, Cross W, Dearnaley DP, Gillessen S, Gilson C, Jones RJ, Langley RE, Malik ZI, Mason MD, Matheson D, Millman R, Russell JM, Thalmann GN, Amos CL, Alonzi R, Bahl A, Birtle A, Din O, Douis H, Eswar C, Gale J, Gannon MR, Jonnada S, Khaksar S, Lester JF, O'Sullivan JM, Parikh OA, Pedley ID, Pudney DM, Sheehan DJ, Srihari NN, Tran ATH, Parmar MKB, Sydes MR; Systemic Therapy for Advanced or Metastatic Prostate cancer: Evaluation of Drug Efficacy (STAMPEDE) investigators.

Lancet. 2018 Dec 1;392(10162):2353-2366. doi: 10.1016/S0140-6736(18)32486-3. Epub 2018 Oct 21.


Audit of transvaginal sonography of normal postmenopausal ovaries by sonographers from the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).

Stott W, Gentry-Maharaj A, Ryan A, Amso N, Seif M, Jones C, Jacobs I, Parmar M, Menon U, Campbell S, Burnell M.

F1000Res. 2018 Aug 10;7:1241. doi: 10.12688/f1000research.15663.1. eCollection 2018.


To the Editor: Postsurgical hypoparathyroidism is not primary hypoparathyroidism.

Parmar MS.

Cleve Clin J Med. 2018 Oct;85(10):735-736. doi: 10.3949/ccjm.85c.10002. No abstract available.


Additive Polyplexes to Undertake siRNA Therapy against CDC20 and Survivin in Breast Cancer Cells.

Parmar MB, K C RB, Löbenberg R, Uludağ H.

Biomacromolecules. 2018 Nov 12;19(11):4193-4206. doi: 10.1021/acs.biomac.8b00918. Epub 2018 Oct 2.


Prognostic value of left ventricular mechanical dyssynchrony indices in long-standing type II diabetes mellitus with normal perfusion and left ventricular systolic functions on SPECT-MPI.

Malik D, Mittal BR, Sood A, Parmar M, Kaur K, Bahl A.

J Nucl Cardiol. 2018 Sep 12. doi: 10.1007/s12350-018-1436-z. [Epub ahead of print]


Delay before drug susceptibility testing among patients with presumptive multidrug-resistant tuberculosis in Gujarat, India.

Shewade HD, Shringarpure KS, Parmar M, Patel N, Kuriya S, Shihora S, Ninama N, Gosai N, Khokhariya R, Popat C, Thanki H, Modi B, Dave P, Baxi RK, Kumar AMV.

Trans R Soc Trop Med Hyg. 2018 Nov 1;112(11):500-508. doi: 10.1093/trstmh/try091.


Phosphorus in kidney disease: Culprit or bystander?

Parmar MS.

Cleve Clin J Med. 2018 Aug;85(8):639-642. doi: 10.3949/ccjm.85a.18013. No abstract available.


Cell-based therapy for Parkinson's disease: A journey through decades toward the light side of the Force.

Parmar M, Torper O, Drouin-Ouellet J.

Eur J Neurosci. 2019 Feb;49(4):463-471. doi: 10.1111/ejn.14109. Epub 2018 Sep 9. Review.

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