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Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development.

Tiklová K, Björklund ÅK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmström F, Joodmardi E, Nilsson M, Parmar M, Perlmann T.

Nat Commun. 2019 Feb 4;10(1):581. doi: 10.1038/s41467-019-08453-1.


Effect of ursodeoxycholic acid in facilitating early hepatic clearance of radiotracer among patients undergoing 99mTc-sestamibi myocardial perfusion scintigraphy: A randomized double blind placebo controlled parallel trial.

Sood A, Singh D, Dutta U, Mittal BR, Parmar M, Kaur G, Kaur K.

J Nucl Cardiol. 2019 Jan 29. doi: 10.1007/s12350-019-01597-z. [Epub ahead of print]


Impact of hibernating and viable myocardium on improvement in perfusion and left ventricular ejection fraction after coronary artery bypass graft.

Arora Y, Singh RS, Sampath S, Sood A, Singh P, Singh H, Mishra AK, Parmar M.

Nucl Med Commun. 2019 Jan 22. doi: 10.1097/MNM.0000000000000976. [Epub ahead of print]


Assessing the impact of efficacy stopping rules on the error rates under the multi-arm multi-stage framework.

Blenkinsop A, Parmar MK, Choodari-Oskooei B.

Clin Trials. 2019 Jan 16:1740774518823551. doi: 10.1177/1740774518823551. [Epub ahead of print]


Nutritional assessment and counselling of tuberculosis patients at primary care in India: do we measure up?

Bhargava M, Bhargava A, Akshaya KM, Shastri SG, Bairy R, Parmar M, Sharath BN.

Int J Tuberc Lung Dis. 2019 Jan 8. doi: 10.5588/ijtld.18.0333. [Epub ahead of print]


Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies.

Henchcliffe C, Parmar M.

J Parkinsons Dis. 2018;8(s1):S131-S137. doi: 10.3233/JPD-181488.


Flip-flop right ventricle myocardial perfusion on stress-rest 99mTc-MIBI myocardial perfusion scintigraphy: An indirect evidence for severe left ventricular coronary arterial disease?

Vadi SK, Mehrotra S, Sood A, Parmar M, Dasagrandhi V, Kaur K, Mittal BR.

J Nucl Cardiol. 2018 Dec 13. doi: 10.1007/s12350-018-01565-z. [Epub ahead of print] No abstract available.


Tuberculosis infection control measures at health care facilities offering HIV and tuberculosis services in India: A baseline assessment.

Sachdeva KS, Deshmukh RD, Seguy NS, Nair SA, Rewari BB, Ramchandran R, Parmar M, Vohra V, Singh S, Ghedia M, Agarwal R, Shah AN, Balasubramanian D, Bamrotiya M, Sikhamani R, Gupta RS, Khaparde SD.

Indian J Tuberc. 2018 Oct;65(4):280-284. doi: 10.1016/j.ijtb.2018.04.004. Epub 2018 Apr 19. Review.


Chronic morbidity and reported disability among older persons from the India Human Development Survey.

Parmar MC, Saikia N.

BMC Geriatr. 2018 Dec 7;18(1):299. doi: 10.1186/s12877-018-0979-9.


Stress-induced ischemia in the right ventricular myocardium on 99mTc-MIBI myocardial perfusion scintigraphy in a rare case of double-chambered right ventricle.

Vadi SK, Rajan P, Sood A, Rohit MK, Parmar M, Kaur K, Mittal BR.

J Nucl Cardiol. 2018 Nov 26. doi: 10.1007/s12350-018-01528-4. [Epub ahead of print] No abstract available.


Exploratory outcome analyses according to stage and/or residual disease in the ICON7 trial of carboplatin and paclitaxel with or without bevacizumab for newly diagnosed ovarian cancer.

González Martín A, Oza AM, Embleton AC, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, Bertrand MA, Beale P, Cervantes A, Kent E, Kaplan RS, Parmar MKB, Scotto N, Perren TJ; ICON7 investigators.

Gynecol Oncol. 2019 Jan;152(1):53-60. doi: 10.1016/j.ygyno.2018.08.036. Epub 2018 Nov 16.


Two Cases of 188Re Microspheres for Inoperable Hepatocellular Carcinoma.

Shukla J, Kalra N, Kumar R, Bhusari P, Chhabra A, Parmar M, Vatsa R, Singh H, Duseja A, Mittal BR.

Clin Nucl Med. 2019 Feb;44(2):e93-e95. doi: 10.1097/RLU.0000000000002373.


Neoadjuvant chemotherapy versus debulking surgery in advanced tubo-ovarian cancers: pooled analysis of individual patient data from the EORTC 55971 and CHORUS trials.

Vergote I, Coens C, Nankivell M, Kristensen GB, Parmar MKB, Ehlen T, Jayson GC, Johnson N, Swart AM, Verheijen R, McCluggage WG, Perren T, Panici PB, Kenter G, Casado A, Mendiola C, Stuart G, Reed NS, Kehoe S; EORTC; MRC CHORUS study investigators.

Lancet Oncol. 2018 Dec;19(12):1680-1687. doi: 10.1016/S1470-2045(18)30566-7. Epub 2018 Nov 6. Erratum in: Lancet Oncol. 2019 Jan;20(1):e10.


Tuberculosis preventive treatment: the next chapter of tuberculosis elimination in India.

Moonan PK, Nair SA, Agarwal R, Chadha VK, Dewan PK, Gupta UD, Ho CS, Holtz TH, Kumar AM, Kumar N, Kumar P, Maloney SA, Mase SR, Oeltmann JE, Paramasivan CN, Parmar MM, Rade KK, Ramachandran R, Rao R, Salhorta VS, Sarin R, Sarin S, Sachdeva KS, Selvaraju S, Singla R, Surie D, Tonsing J, Tripathy SP, Khaparde SD.

BMJ Glob Health. 2018 Oct 8;3(5):e001135. doi: 10.1136/bmjgh-2018-001135. eCollection 2018.


Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.

Parker CC, James ND, Brawley CD, Clarke NW, Hoyle AP, Ali A, Ritchie AWS, Attard G, Chowdhury S, Cross W, Dearnaley DP, Gillessen S, Gilson C, Jones RJ, Langley RE, Malik ZI, Mason MD, Matheson D, Millman R, Russell JM, Thalmann GN, Amos CL, Alonzi R, Bahl A, Birtle A, Din O, Douis H, Eswar C, Gale J, Gannon MR, Jonnada S, Khaksar S, Lester JF, O'Sullivan JM, Parikh OA, Pedley ID, Pudney DM, Sheehan DJ, Srihari NN, Tran ATH, Parmar MKB, Sydes MR; Systemic Therapy for Advanced or Metastatic Prostate cancer: Evaluation of Drug Efficacy (STAMPEDE) investigators.

Lancet. 2018 Dec 1;392(10162):2353-2366. doi: 10.1016/S0140-6736(18)32486-3. Epub 2018 Oct 21.


Audit of transvaginal sonography of normal postmenopausal ovaries by sonographers from the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).

Stott W, Gentry-Maharaj A, Ryan A, Amso N, Seif M, Jones C, Jacobs I, Parmar M, Menon U, Campbell S, Burnell M.

F1000Res. 2018 Aug 10;7:1241. doi: 10.12688/f1000research.15663.1. eCollection 2018.


To the Editor: Postsurgical hypoparathyroidism is not primary hypoparathyroidism.

Parmar MS.

Cleve Clin J Med. 2018 Oct;85(10):735-736. doi: 10.3949/ccjm.85c.10002. No abstract available.


Additive Polyplexes to Undertake siRNA Therapy against CDC20 and Survivin in Breast Cancer Cells.

Parmar MB, K C RB, Löbenberg R, Uludağ H.

Biomacromolecules. 2018 Nov 12;19(11):4193-4206. doi: 10.1021/acs.biomac.8b00918. Epub 2018 Oct 2.


Prognostic value of left ventricular mechanical dyssynchrony indices in long-standing type II diabetes mellitus with normal perfusion and left ventricular systolic functions on SPECT-MPI.

Malik D, Mittal BR, Sood A, Parmar M, Kaur K, Bahl A.

J Nucl Cardiol. 2018 Sep 12. doi: 10.1007/s12350-018-1436-z. [Epub ahead of print]


Delay before drug susceptibility testing among patients with presumptive multidrug-resistant tuberculosis in Gujarat, India.

Shewade HD, Shringarpure KS, Parmar M, Patel N, Kuriya S, Shihora S, Ninama N, Gosai N, Khokhariya R, Popat C, Thanki H, Modi B, Dave P, Baxi RK, Kumar AMV.

Trans R Soc Trop Med Hyg. 2018 Nov 1;112(11):500-508. doi: 10.1093/trstmh/try091.


Phosphorus in kidney disease: Culprit or bystander?

Parmar MS.

Cleve Clin J Med. 2018 Aug;85(8):639-642. doi: 10.3949/ccjm.85a.18013. No abstract available.


Cell-based therapy for Parkinson's disease: A journey through decades toward the light side of the Force.

Parmar M, Torper O, Drouin-Ouellet J.

Eur J Neurosci. 2018 Aug 12. doi: 10.1111/ejn.14109. [Epub ahead of print] Review.


Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation.

Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA, Jakobsson J.

Cell Rep. 2018 Aug 7;24(6):1397-1406. doi: 10.1016/j.celrep.2018.07.017.


Comparison of Longitudinal CA125 Algorithms as a First-Line Screen for Ovarian Cancer in the General Population.

Blyuss O, Burnell M, Ryan A, Gentry-Maharaj A, Mariño IP, Kalsi J, Manchanda R, Timms JF, Parmar M, Skates SJ, Jacobs I, Zaikin A, Menon U.

Clin Cancer Res. 2018 Oct 1;24(19):4726-4733. doi: 10.1158/1078-0432.CCR-18-0208. Epub 2018 Jul 3.


Phenytoin Could Potentially Increase Hepatic Clearance of 99mTc-Sestamibi in Myocardial Perfusion Imaging.

Kavanal AJ, Singh D, Sood A, Parmar M, Mittal BR.

Clin Nucl Med. 2018 Sep;43(9):e341-e342. doi: 10.1097/RLU.0000000000002199.


Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study.

Brown LC, Ahmed HU, Faria R, El-Shater Bosaily A, Gabe R, Kaplan RS, Parmar M, Collaco-Moraes Y, Ward K, Hindley RG, Freeman A, Kirkham A, Oldroyd R, Parker C, Bott S, Burns-Cox N, Dudderidge T, Ghei M, Henderson A, Persad R, Rosario DJ, Shergill I, Winkler M, Soares M, Spackman E, Sculpher M, Emberton M.

Health Technol Assess. 2018 Jul;22(39):1-176. doi: 10.3310/hta22390.


Can 99mTc-labeled RBC-equilibrium radionuclide angiocardiography be an adjunct imaging biomarker for marrow hyperplasia in beta-thalassemia major patients?

Vadi SK, Kashyap S, Sood A, Khadwal A, Parmar M, Parihar AS, Mittal BR.

J Nucl Cardiol. 2018 Jul 23. doi: 10.1007/s12350-018-1380-y. [Epub ahead of print] No abstract available.


Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer.

Basu B, Krebs MG, Sundar R, Wilson RH, Spicer J, Jones R, Brada M, Talbot DC, Steele N, Ingles Garces AH, Brugger W, Harrington EA, Evans J, Hall E, Tovey H, de Oliveira FM, Carreira S, Swales K, Ruddle R, Raynaud FI, Purchase B, Dawes JC, Parmar M, Turner AJ, Tunariu N, Banerjee S, de Bono JS, Banerji U.

Ann Oncol. 2018 Sep 1;29(9):1918-1925. doi: 10.1093/annonc/mdy245.


Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats.

Cardoso T, Adler AF, Mattsson B, Hoban DB, Nolbrant S, Wahlestedt JN, Kirkeby A, Grealish S, Björklund A, Parmar M.

J Comp Neurol. 2018 Sep 1;526(13):2133-2146. doi: 10.1002/cne.24500. Epub 2018 Jul 31.


Delay and attrition before treatment initiation among MDR-TB patients in five districts of Gujarat, India.

Shewade HD, Shringarpure KS, Parmar M, Patel N, Kuriya S, Shihora S, Ninama N, Gosai N, Khokhariya R, Popat C, Thanki H, Modi B, Dave P, Baxi RK, Kumar AMV.

Public Health Action. 2018 Jun 21;8(2):59-65. doi: 10.5588/pha.18.0003.


Active case finding of rifampicin sensitive and resistant TB among household contacts of drug resistant TB patients in Andhra Pradesh and Telangana states of India - A systematic screening intervention.

Chatla C, Jaju J, Achanta S, Samyuktha R, Chakramahanti S, Purad C, Chepuri R, Nair SA, Parmar M.

Indian J Tuberc. 2018 Jul;65(3):218-224. doi: 10.1016/j.ijtb.2018.02.004. Epub 2018 Feb 11.


Rethinking non-inferiority: a practical trial design for optimising treatment duration.

Quartagno M, Walker AS, Carpenter JR, Phillips PP, Parmar MK.

Clin Trials. 2018 Oct;15(5):477-488. doi: 10.1177/1740774518778027. Epub 2018 Jun 5.


What is the optimal systemic treatment of men with metastatic, hormone-naive prostate cancer? A STOPCAP systematic review and network meta-analysis.

Vale CL, Fisher DJ, White IR, Carpenter JR, Burdett S, Clarke NW, Fizazi K, Gravis G, James ND, Mason MD, Parmar MKB, Rydzewska LH, Sweeney CJ, Spears MR, Sydes MR, Tierney JF.

Ann Oncol. 2018 May 1;29(5):1249-1257. doi: 10.1093/annonc/mdy071.


Developing defined substrates for stem cell culture and differentiation.

Hagbard L, Cameron K, August P, Penton C, Parmar M, Hay DC, Kallur T.

Philos Trans R Soc Lond B Biol Sci. 2018 Jul 5;373(1750). pii: 20170230. doi: 10.1098/rstb.2017.0230. Review.


New approaches for brain repair-from rescue to reprogramming.

Barker RA, Götz M, Parmar M.

Nature. 2018 May;557(7705):329-334. doi: 10.1038/s41586-018-0087-1. Epub 2018 May 16. Review.


Provider reported barriers and solutions to improve testing among tuberculosis patients 'eligible for drug susceptibility test': A qualitative study from programmatic setting in India.

Shewade HD, Kokane AM, Singh AR, Parmar M, Verma M, Desikan P, Khan SN, Kumar AMV.

PLoS One. 2018 Apr 20;13(4):e0196162. doi: 10.1371/journal.pone.0196162. eCollection 2018.


Response to letter commenting on published paper: Adding abiraterone to androgen deprivation therapy in men with metastatic hormone-sensitive prostate cancer: A systematic review and meta-analysis.

Rydzewska LHM, Burdett S, Vale CL, Parmar MKB, Tierney JF.

Eur J Cancer. 2018 May;94:218-219. doi: 10.1016/j.ejca.2018.02.002. Epub 2018 Mar 13. No abstract available.


Adding abiraterone or docetaxel to long-term hormone therapy for prostate cancer: directly randomised data from the STAMPEDE multi-arm, multi-stage platform protocol.

Sydes MR, Spears MR, Mason MD, Clarke NW, Dearnaley DP, de Bono JS, Attard G, Chowdhury S, Cross W, Gillessen S, Malik ZI, Jones R, Parker CC, Ritchie AWS, Russell JM, Millman R, Matheson D, Amos C, Gilson C, Birtle A, Brock S, Capaldi L, Chakraborti P, Choudhury A, Evans L, Ford D, Gale J, Gibbs S, Gilbert DC, Hughes R, McLaren D, Lester JF, Nikapota A, O'Sullivan J, Parikh O, Peedell C, Protheroe A, Rudman SM, Shaffer R, Sheehan D, Simms M, Srihari N, Strebel R, Sundar S, Tolan S, Tsang D, Varughese M, Wagstaff J, Parmar MKB, James ND; STAMPEDE Investigators.

Ann Oncol. 2018 May 1;29(5):1235-1248. doi: 10.1093/annonc/mdy072.


Use of Verbal Autopsy to Determine Underlying Cause of Death during Treatment of Multidrug-Resistant Tuberculosis, India.

Naik PR, Moonan PK, Nirgude AS, Shewade HD, Satyanarayana S, Raghuveer P, Parmar M, Ravichandra C, Singarajipura A.

Emerg Infect Dis. 2018 Mar;24(3):478-484. doi: 10.3201/eid2403.171718.


Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts.

Shrigley S, Pircs K, Barker RA, Parmar M, Drouin-Ouellet J.

J Vis Exp. 2018 Feb 5;(132). doi: 10.3791/56904.


Left ventricular mechanical dyssynchrony assessment in long-standing type II diabetes mellitus patients with normal gated SPECT-MPI.

Malik D, Mittal B, Sood A, Parmar M, Kaur G, Bahl A.

J Nucl Cardiol. 2018 Feb 1. doi: 10.1007/s12350-018-1208-9. [Epub ahead of print]


Transdermal oestradiol as a method of androgen suppression for prostate cancer within the STAMPEDE trial platform.

Gilbert DC, Duong T, Sydes M, Bara A, Clarke N, Abel P, James N, Langley R, Parmar M; STAMPEDE and PATCH Trial Management Groups.

BJU Int. 2018 May;121(5):680-683. doi: 10.1111/bju.14153. Epub 2018 Feb 28. No abstract available.


Social support a key factor for adherence to multidrug-resistant tuberculosis treatment.

Deshmukh RD, Dhande DJ, Sachdeva KS, Sreenivas AN, Kumar AMV, Parmar M.

Indian J Tuberc. 2018 Jan;65(1):41-47. doi: 10.1016/j.ijtb.2017.05.003. Epub 2017 Jun 2.


Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus.

Avaliani N, Pfisterer U, Heuer A, Parmar M, Kokaia M, Andersson M.

Stem Cells Int. 2017;2017:5718608. doi: 10.1155/2017/5718608. Epub 2017 Nov 26.


Towards stem cell based therapies for Parkinson's disease.

Parmar M.

Development. 2018 Jan 8;145(1). pii: dev156117. doi: 10.1242/dev.156117. Review.


Self-Assembling Peptide Nanoscaffold That Activates Human Mast Cells.

Lu L, Parmar MB, Kulka M, Kwan P, Unsworth LD.

ACS Appl Mater Interfaces. 2018 Feb 21;10(7):6107-6117. doi: 10.1021/acsami.7b14560. Epub 2018 Feb 12.


Resveratrol and pinostilbene confer neuroprotection against aging-related deficits through an ERK1/2-dependent mechanism.

Allen EN, Potdar S, Tapias V, Parmar M, Mizuno CS, Rimando A, Cavanaugh JE.

J Nutr Biochem. 2018 Apr;54:77-86. doi: 10.1016/j.jnutbio.2017.10.015. Epub 2017 Nov 4.


Combinational siRNA delivery using hyaluronic acid modified amphiphilic polyplexes against cell cycle and phosphatase proteins to inhibit growth and migration of triple-negative breast cancer cells.

Parmar MB, Meenakshi Sundaram DN, K C RB, Maranchuk R, Montazeri Aliabadi H, Hugh JC, Löbenberg R, Uludağ H.

Acta Biomater. 2018 Jan 15;66:294-309. doi: 10.1016/j.actbio.2017.11.036. Epub 2017 Nov 26.


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