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Items: 1 to 50 of 155

1.

Direct pulmonary delivery of solubilized curcumin reduces severity of lethal pneumonia.

Zhang B, Swamy S, Balijepalli S, Panicker S, Mooliyil J, Sherman MA, Parkkinen J, Raghavendran K, Suresh MV.

FASEB J. 2019 Dec;33(12):13294-13309. doi: 10.1096/fj.201901047RR. Epub 2019 Sep 17.

PMID:
31530014
2.

Histopathological patterns seen around failed metal-on-metal hip replacements: Cluster and latent class analysis of patterns of failure.

Reito A, Lehtovirta L, Parkkinen J, Eskelinen A.

J Biomed Mater Res B Appl Biomater. 2019 Aug 13. doi: 10.1002/jbm.b.34460. [Epub ahead of print]

PMID:
31410972
3.

Host-specific factors affect the pathogenesis of adverse reaction to metal debris.

Lehtovirta L, Reito A, Lainiala O, Parkkinen J, Hothi H, Henckel J, Hart A, Eskelinen A.

BMC Musculoskelet Disord. 2019 May 4;20(1):195. doi: 10.1186/s12891-019-2578-0.

4.

Curcumin as Treatment for Bladder Cancer: A Preclinical Study of Cyclodextrin-Curcumin Complex and BCG as Intravesical Treatment in an Orthotopic Bladder Cancer Rat Model.

Falke J, Parkkinen J, Vaahtera L, Hulsbergen-van de Kaa CA, Oosterwijk E, Witjes JA.

Biomed Res Int. 2018 Jun 10;2018:9634902. doi: 10.1155/2018/9634902. eCollection 2018.

5.

Tibia Adamantinoma Resection and Reconstruction with a Custom-Made Total Tibia Endoprosthesis: A Case Report with 8-Year Follow-Up.

Kask G, Pakarinen TK, Parkkinen J, Kuokkanen H, Nieminen J, Laitinen MK.

Case Rep Orthop. 2018 Jun 6;2018:3656913. doi: 10.1155/2018/3656913. eCollection 2018.

6.

Solitary juvenile xanthogranuloma in the spine pretreated with neoadjuvant denosumab therapy followed by surgical resection in a 5-year-old child: case report and literature review.

Irmola T, Laitinen MK, Parkkinen J, Engellau J, Neva MH.

Eur Spine J. 2018 Jul;27(Suppl 3):555-560. doi: 10.1007/s00586-018-5651-8. Epub 2018 Jun 6. Review.

PMID:
29876657
7.

Association between periprosthetic tissue metal content, whole blood and synovial fluid metal ion levels and histopathological findings in patients with failed metal-on-metal hip replacement.

Lehtovirta L, Reito A, Parkkinen J, Peräniemi S, Vepsäläinen J, Eskelinen A.

PLoS One. 2018 May 16;13(5):e0197614. doi: 10.1371/journal.pone.0197614. eCollection 2018.

8.

Analysis of bearing wear, whole blood and synovial fluid metal ion concentrations and histopathological findings in patients with failed ASR hip resurfacings.

Lehtovirta L, Reito A, Parkkinen J, Hothi H, Henckel J, Hart A, Eskelinen A.

BMC Musculoskelet Disord. 2017 Dec 11;18(1):523. doi: 10.1186/s12891-017-1894-5.

9.

Hepatocellular uptake of cyclodextrin-complexed curcumin during liver preservation: A feasibility study.

Saidi SA, Meurisse N, Jochmans I, Heedfeld V, Wylin T, Parkkinen J, Pirenne J, Monbaliu D, El Feki A, van Pelt J.

Biopharm Drug Dispos. 2018 Jan;39(1):18-29. doi: 10.1002/bdd.2108. Epub 2017 Nov 20.

PMID:
28972677
10.

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury.

Kohonen P, Parkkinen JA, Willighagen EL, Ceder R, Wennerberg K, Kaski S, Grafström RC.

Nat Commun. 2017 Jul 3;8:15932. doi: 10.1038/ncomms15932.

11.

Outcomes After Flexor Tendon Repair Combined With the Application of Human Amniotic Membrane Allograft.

Leppänen OV, Karjalainen T, Göransson H, Hakamäki A, Havulinna J, Parkkinen J, Jokihaara J.

J Hand Surg Am. 2017 Jun;42(6):474.e1-474.e8. doi: 10.1016/j.jhsa.2017.03.006. Epub 2017 Mar 30.

PMID:
28365148
12.

High blood metal ion levels in 19 of 22 patients with metal-on-metal hinge knee replacements.

Laitinen M, Nieminen J, Reito A, Pakarinen TK, Suomalainen P, Pamilo K, Parkkinen J, Lont T, Eskelinen A.

Acta Orthop. 2017 Jun;88(3):269-274. doi: 10.1080/17453674.2017.1283846. Epub 2017 Jan 26.

13.

Mesotheliomas show higher hyaluronan positivity around tumor cells than metastatic pulmonary adenocarcinomas.

Törrönen K, Soini Y, Pääkkö P, Parkkinen J, Sironen R, Rilla K.

Histol Histopathol. 2016 Oct;31(10):1113-22. doi: 10.14670/HH-11-740. Epub 2016 Feb 25.

PMID:
26912058
14.

Diagnostic utility of joint fluid metal ion measurement for histopathological findings in metal-on-metal hip replacements.

Reito A, Parkkinen J, Puolakka T, Pajamäki J, Eskelinen A.

BMC Musculoskelet Disord. 2015 Dec 22;16:393. doi: 10.1186/s12891-015-0851-4.

15.

Genetic alterations in periprosthetic soft-tissue masses from patients with metal-on-metal hip replacement.

Sarhadi VK, Parkkinen J, Reito A, Nieminen J, Porkka N, Wirtanen T, Laitinen M, Eskelinen A, Knuutila S.

Mutat Res. 2015 Nov;781:1-6. doi: 10.1016/j.mrfmmm.2015.08.006. Epub 2015 Aug 29.

PMID:
26355908
16.

The European Gaucher Alliance: a survey of member patient organisations' activities, healthcare environments and concerns.

Žnidar I, Collin-Histed T, Niemeyer P, Parkkinen J, Lauridsen AG, Zariņa S, Cohen Y, Manuel J.

Orphanet J Rare Dis. 2014 Sep 2;9:134. doi: 10.1186/s13023-014-0134-4.

17.

Probabilistic drug connectivity mapping.

Parkkinen JA, Kaski S.

BMC Bioinformatics. 2014 Apr 17;15:113. doi: 10.1186/1471-2105-15-113.

18.

Cyclodextrin curcumin formulation improves outcome in a preclinical pig model of marginal kidney transplantation.

Thuillier R, Allain G, Giraud S, Saintyves T, Delpech PO, Couturier P, Billault C, Marchand E, Vaahtera L, Parkkinen J, Hauet T.

Am J Transplant. 2014 May;14(5):1073-83. doi: 10.1111/ajt.12661. Epub 2014 Mar 11.

19.

Assessing warm ischemic injury of pig livers at hypothermic machine perfusion.

Liu Q, Vekemans K, Iania L, Komuta M, Parkkinen J, Heedfeld V, Wylin T, Monbaliu D, Pirenne J, van Pelt J.

J Surg Res. 2014 Jan;186(1):379-89. doi: 10.1016/j.jss.2013.07.034. Epub 2013 Aug 8.

PMID:
24035230
20.

Comparison of bleomycin-detectable iron and labile plasma iron assays.

Itkonen O, Vaahtera L, Parkkinen J.

Clin Chem. 2013 Aug;59(8):1271-3. doi: 10.1373/clinchem.2013.205302. Epub 2013 May 13. No abstract available.

PMID:
23669528
21.

Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs.

Khan SA, Faisal A, Mpindi JP, Parkkinen JA, Kalliokoski T, Poso A, Kallioniemi OP, Wennerberg K, Kaski S.

BMC Bioinformatics. 2012 May 30;13:112. doi: 10.1186/1471-2105-13-112.

22.

Binding of hepcidin to plasma proteins.

Itkonen O, Stenman UH, Parkkinen J, Soliymani R, Baumann M, Hämäläinen E.

Clin Chem. 2012 Jul;58(7):1158-60. doi: 10.1373/clinchem.2012.186916. Epub 2012 May 14. No abstract available.

PMID:
22586325
23.

Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats.

Eräranta A, Riutta A, Fan M, Koskela J, Tikkanen I, Lakkisto P, Niemelä O, Parkkinen J, Mustonen J, Pörsti I.

Am J Nephrol. 2012;35(5):401-8. doi: 10.1159/000337942. Epub 2012 Apr 19.

PMID:
22517117
24.

Genes involved in systemic and arterial bed dependent atherosclerosis--Tampere Vascular study.

Levula M, Oksala N, Airla N, Zeitlin R, Salenius JP, Järvinen O, Venermo M, Partio T, Saarinen J, Somppi T, Suominen V, Virkkunen J, Hautalahti J, Laaksonen R, Kähönen M, Mennander A, Kytömäki L, Soini JT, Parkkinen J, Pelto-Huikko M, Lehtimäki T.

PLoS One. 2012;7(4):e33787. doi: 10.1371/journal.pone.0033787. Epub 2012 Apr 11.

25.

Pulmonary administration of a water-soluble curcumin complex reduces severity of acute lung injury.

Suresh MV, Wagner MC, Rosania GR, Stringer KA, Min KA, Risler L, Shen DD, Georges GE, Reddy AT, Parkkinen J, Reddy RC.

Am J Respir Cell Mol Biol. 2012 Sep;47(3):280-7. doi: 10.1165/rcmb.2011-0175OC. Epub 2012 Feb 3.

26.

Preanalytical factors and reference intervals for serum hepcidin LC-MS/MS method.

Itkonen O, Parkkinen J, Stenman UH, Hämäläinen E.

Clin Chim Acta. 2012 Apr 11;413(7-8):696-701. doi: 10.1016/j.cca.2011.12.015. Epub 2011 Dec 24.

PMID:
22222553
27.

Highlight detection and removal from spectral image.

Koirala P, Pant P, Hauta-Kasari M, Parkkinen J.

J Opt Soc Am A Opt Image Sci Vis. 2011 Nov 1;28(11):2284-91. doi: 10.1364/JOSAA.28.002284.

PMID:
22048296
28.

Addition of a water-soluble propofol formulation to preservation solution in experimental kidney transplantation.

Snoeijs MG, Vaahtera L, de Vries EE, Schurink GW, Haenen GR, Peutz-Kootstra CJ, Buurman WA, van Heurn LW, Parkkinen J.

Transplantation. 2011 Aug 15;92(3):296-302. doi: 10.1097/TP.0b013e3182247b78.

PMID:
21709605
29.

Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma.

Korpi JT, Hagström J, Lehtonen N, Parkkinen J, Sorsa T, Salo T, Laitinen M.

Surg Oncol. 2011 Mar;20(1):e18-22. doi: 10.1016/j.suronc.2010.08.004. Epub 2010 Sep 29. Review.

PMID:
20880700
30.

Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake.

Yadav VR, Prasad S, Kannappan R, Ravindran J, Chaturvedi MM, Vaahtera L, Parkkinen J, Aggarwal BB.

Biochem Pharmacol. 2010 Oct 1;80(7):1021-32. doi: 10.1016/j.bcp.2010.06.022. Epub 2010 Jun 23. Retraction in: Biochem Pharmacol. 2016 Feb 15;102:142.

31.

Searching for functional gene modules with interaction component models.

Parkkinen JA, Kaski S.

BMC Syst Biol. 2010 Jan 25;4:4. doi: 10.1186/1752-0509-4-4.

32.

Multifactorial biological modulation of warm ischemia reperfusion injury in liver transplantation from non-heart-beating donors eliminates primary nonfunction and reduces bile salt toxicity.

Monbaliu D, Vekemans K, Hoekstra H, Vaahtera L, Libbrecht L, Derveaux K, Parkkinen J, Liu Q, Heedfeld V, Wylin T, Deckx H, Zeegers M, Balligand E, Buurman W, van Pelt J, Porte RJ, Pirenne J.

Ann Surg. 2009 Nov;250(5):808-17. doi: 10.1097/SLA.0b013e3181bdd787.

PMID:
19826248
33.

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study.

Levula M, Airla N, Oksala N, Hernesniemi JA, Pelto-Huikko M, Salenius JP, Zeitlin R, Järvinen O, Huovila AP, Nikkari ST, Jaakkola O, Ilveskoski E, Mikkelsson J, Perola M, Laaksonen R, Kytömäki L, Soini JT, Kähönen M, Parkkinen J, Karhunen PJ, Lehtimäki T.

Ann Med. 2009;41(7):497-507. doi: 10.1080/07853890903025945.

PMID:
19575316
34.

Non-transferrin-bound iron in haematological patients during chemotherapy and conditioning for autologous stem cell transplantation.

Sahlstedt L, von Bonsdorff L, Ebeling F, Parkkinen J, Juvonen E, Ruutu T.

Eur J Haematol. 2009 Nov;83(5):455-9. doi: 10.1111/j.1600-0609.2009.01310.x. Epub 2009 Jul 1.

PMID:
19572995
35.

Port-site metastasis following laparoscopic hysterectomy and bilateral salpingo-ophorectomy for endometrial carcinoma.

Mäenpää JU, Nyberg R, Parkkinen J.

Eur J Obstet Gynecol Reprod Biol. 2009 Mar;143(1):61-2. doi: 10.1016/j.ejogrb.2008.11.002. Epub 2009 Jan 10. No abstract available.

PMID:
19136193
36.

Transplantation of allogeneic T cells alters iron homeostasis in NOD/SCID mice.

Bair S, Spaulding E, Parkkinen J, Shulman HM, Lesnikov V, Beauchamp M, Canonne-Hergaux F, Kowdley KV, Deeg HJ.

Blood. 2009 Feb 19;113(8):1841-4. doi: 10.1182/blood-2008-09-178517. Epub 2008 Dec 23.

37.

Diffractive parameric colors.

Orava J, Heikkila N, Jaaskelainen T, Parkkinen J.

J Opt Soc Am A Opt Image Sci Vis. 2008 Dec;25(12):2901-7.

PMID:
19037379
38.

Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells.

Ryhänen T, Hyttinen JM, Kopitz J, Rilla K, Kuusisto E, Mannermaa E, Viiri J, Holmberg CI, Immonen I, Meri S, Parkkinen J, Eskelinen EL, Uusitalo H, Salminen A, Kaarniranta K.

J Cell Mol Med. 2009 Sep;13(9B):3616-31. doi: 10.1111/j.1582-4934.2008.00577.x. Epub 2008 Nov 6.

39.

Kernel-based spectral color image segmentation.

Li H, Bochko V, Jaaskelainen T, Parkkinen J, Shen IF.

J Opt Soc Am A Opt Image Sci Vis. 2008 Nov;25(11):2805-16.

PMID:
18978860
40.

Evaluation and unification of some methods for estimating reflectance spectra from RGB images.

Heikkinen V, Lenz R, Jetsu T, Parkkinen J, Hauta-Kasari M, Jääskeläinen T.

J Opt Soc Am A Opt Image Sci Vis. 2008 Oct;25(10):2444-58.

PMID:
18830322
41.

Weighted compression of spectral color information.

Laamanen H, Jetsu T, Jaaskelainen T, Parkkinen J.

J Opt Soc Am A Opt Image Sci Vis. 2008 Jun;25(6):1383-8.

PMID:
18516149
42.

Acyl chain-dependent effect of lysophosphatidylcholine on human neutrophils.

Ojala PJ, Hirvonen TE, Hermansson M, Somerharju P, Parkkinen J.

J Leukoc Biol. 2007 Dec;82(6):1501-9. Epub 2007 Sep 20.

PMID:
17884992
43.

Regularized learning framework in the estimation of reflectance spectra from camera responses.

Heikkinen V, Jetsu T, Parkkinen J, Hauta-Kasari M, Jaaskelainen T, Lee SD.

J Opt Soc Am A Opt Image Sci Vis. 2007 Sep;24(9):2673-83.

PMID:
17767236
44.

Heme oxygenase 1 gene polymorphisms and outcome of renal transplantation.

Turpeinen H, Kyllönen LE, Parkkinen J, Laine J, Salmela KT, Partanen J.

Int J Immunogenet. 2007 Aug;34(4):253-7.

PMID:
17627760
45.

Inhibition of erythroid and granulocyte-macrophage colony formation by non-transferrin-bound iron in vitro: protective effect of apotransferrin.

Juvonen E, Sahlstedt L, Parkkinen J, Ruutu T.

Eur J Haematol. 2007 Aug;79(2):126-31. Epub 2007 Jun 27.

PMID:
17596197
46.

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.

Pirinen E, Kuulasmaa T, Pietilä M, Heikkinen S, Tusa M, Itkonen P, Boman S, Skommer J, Virkamäki A, Hohtola E, Kettunen M, Fatrai S, Kansanen E, Koota S, Niiranen K, Parkkinen J, Levonen AL, Ylä-Herttuala S, Hiltunen JK, Alhonen L, Smith U, Jänne J, Laakso M.

Mol Cell Biol. 2007 Jul;27(13):4953-67. Epub 2007 May 7.

47.

Sentinel node and vulvar cancer: a series of 47 patients.

Nyberg RH, Iivonen M, Parkkinen J, Kuoppala T, Mäenpää JU.

Acta Obstet Gynecol Scand. 2007;86(5):615-9.

PMID:
17464593
48.

Inhibition of ERK1/2 activation by phenolic antioxidants protects kidney tubular cells during cold storage.

Karhumäki P, Tiitinen SL, Turpeinen H, Parkkinen J.

Transplantation. 2007 Apr 15;83(7):948-53.

PMID:
17460567
49.

Primary graft nonfunction and Kupffer cell activation after liver transplantation from non-heart-beating donors in pigs.

Monbaliu D, van Pelt J, De Vos R, Greenwood J, Parkkinen J, Crabbé T, Zeegers M, Vekemans K, Pincemail J, Defraigne JO, Fevery J, Pirenne J.

Liver Transpl. 2007 Feb;13(2):239-47.

50.

Molecular mechanisms underlying neuroprotective effects of albumin after ischemic stroke.

Parkkinen J, Ojala P, Niiranen J, Jolkkonen J.

Stroke. 2007 Feb;38(2):255; author reply 256. Epub 2006 Dec 14. No abstract available.

PMID:
17170360

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