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Items: 1 to 50 of 85

1.

Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection.

Li B, Clohisey SM, Chia BS, Wang B, Cui A, Eisenhaure T, Schweitzer LD, Hoover P, Parkinson NJ, Nachshon A, Smith N, Regan T, Farr D, Gutmann MU, Bukhari SI, Law A, Sangesland M, Gat-Viks I, Digard P, Vasudevan S, Lingwood D, Dockrell DH, Doench JG, Baillie JK, Hacohen N.

Nat Commun. 2020 Jan 9;11(1):164. doi: 10.1038/s41467-019-13965-x.

2.

Catheter-associated venous air embolism in hospitalized horses: 32 cases.

Parkinson NJ, McKenzie HC, Barton MH, Davis JL, Dunkel B, Johnson AL, MacDonald ES.

J Vet Intern Med. 2018 Mar;32(2):805-814. doi: 10.1111/jvim.15057. Epub 2018 Feb 20.

3.

Reply to Brioude et al.

Brzezinski J, Shuman C, Choufani S, Ray P, Stavropoulos DJ, Basran R, Steele L, Parkinson N, Grant R, Thorner P, Lorenzo A, Weksberg R.

Eur J Hum Genet. 2018 Apr;26(4):473-474. doi: 10.1038/s41431-017-0094-y. Epub 2018 Feb 15. No abstract available.

4.

Wilms tumour in Beckwith-Wiedemann Syndrome and loss of methylation at imprinting centre 2: revisiting tumour surveillance guidelines.

Brzezinski J, Shuman C, Choufani S, Ray P, Stavropoulos DJ, Basran R, Steele L, Parkinson N, Grant R, Thorner P, Lorenzo A, Weksberg R.

Eur J Hum Genet. 2017 Sep;25(9):1031-1039. doi: 10.1038/ejhg.2017.102. Epub 2017 Jul 12.

5.

Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis.

Robb CT, McSorley HJ, Lee J, Aoki T, Yu C, Crittenden S, Astier A, Felton JM, Parkinson N, Ayele A, Breyer RM, Anderton SM, Narumiya S, Rossi AG, Howie SE, Guttman-Yassky E, Weller RB, Yao C.

J Allergy Clin Immunol. 2018 Jan;141(1):152-162. doi: 10.1016/j.jaci.2017.04.045. Epub 2017 Jun 3.

6.

Characterization of basal and lipopolysaccharide-induced microRNA expression in equine peripheral blood mononuclear cells using Next-Generation Sequencing.

Parkinson NJ, Buechner-Maxwell VA, Witonsky SG, Pleasant RS, Werre SR, Ahmed SA.

PLoS One. 2017 May 26;12(5):e0177664. doi: 10.1371/journal.pone.0177664. eCollection 2017.

7.

Whole Genome Sequencing Expands Diagnostic Utility and Improves Clinical Management in Pediatric Medicine.

Stavropoulos DJ, Merico D, Jobling R, Bowdin S, Monfared N, Thiruvahindrapuram B, Nalpathamkalam T, Pellecchia G, Yuen RKC, Szego MJ, Hayeems RZ, Shaul RZ, Brudno M, Girdea M, Frey B, Alipanahi B, Ahmed S, Babul-Hirji R, Porras RB, Carter MT, Chad L, Chaudhry A, Chitayat D, Doust SJ, Cytrynbaum C, Dupuis L, Ejaz R, Fishman L, Guerin A, Hashemi B, Helal M, Hewson S, Inbar-Feigenberg M, Kannu P, Karp N, Kim R, Kronick J, Liston E, MacDonald H, Mercimek-Mahmutoglu S, Mendoza-Londono R, Nasr E, Nimmo G, Parkinson N, Quercia N, Raiman J, Roifman M, Schulze A, Shugar A, Shuman C, Sinajon P, Siriwardena K, Weksberg R, Yoon G, Carew C, Erickson R, Leach RA, Klein R, Ray PN, Meyn MS, Scherer SW, Cohn RD, Marshall CR.

NPJ Genom Med. 2016 Jan 13;1. pii: 15012. doi: 10.1038/npjgenmed.2015.12.

8.

Water based scale-up of CPO-27 synthesis for nitric oxide delivery.

Cattaneo D, Warrender SJ, Duncan MJ, Castledine R, Parkinson N, Haley I, Morris RE.

Dalton Trans. 2016 Jan 14;45(2):618-29. doi: 10.1039/c5dt03955j.

PMID:
26616891
9.

Detection of the Bacterial Potato Pathogens Pectobacterium and Dickeya spp. Using Conventional and Real-Time PCR.

Humphris SN, Cahill G, Elphinstone JG, Kelly R, Parkinson NM, Pritchard L, Toth IK, Saddler GS.

Methods Mol Biol. 2015;1302:1-16. doi: 10.1007/978-1-4939-2620-6_1.

PMID:
25981242
10.

Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes.

Parkinson NJ, Roddis M, Ferneyhough B, Zhang G, Marsden AJ, Maslau S, Sanchez-Pearson Y, Barthlott T, Humphreys IR, Ladell K, Price DA, Ponting CP, Hollander G, Fischer MD.

Genome Res. 2015 Feb;25(2):226-34. doi: 10.1101/gr.179770.114. Epub 2014 Nov 3.

11.

Paternal germline mosaicism for a GPC3 deletion in X-linked Simpson-Golabi-Behmel syndrome.

Agatep R, Shuman C, Steele L, Parkinson N, Weksberg R, Stockley TL.

Am J Med Genet A. 2014 Oct;164A(10):2682-4. doi: 10.1002/ajmg.a.36682. Epub 2014 Jul 29. No abstract available.

PMID:
25073799
12.

Alcohol misuse among university staff: a cross-sectional study.

Awoliyi S, Ball D, Parkinson N, Preedy VR.

PLoS One. 2014 Jul 29;9(7):e98134. doi: 10.1371/journal.pone.0098134. eCollection 2014.

13.

Dickeya aquatica sp. nov., isolated from waterways.

Parkinson N, DeVos P, Pirhonen M, Elphinstone J.

Int J Syst Evol Microbiol. 2014 Jul;64(Pt 7):2264-6. doi: 10.1099/ijs.0.058693-0. Epub 2014 Apr 9.

PMID:
24719023
14.

Thomas Fresh (1803-1861), Inspector of Nuisances, Liverpool's first public health officer.

Parkinson N.

J Med Biogr. 2013 Nov;21(4):238-49. doi: 10.1177/0967772013479277. Epub 2013 Jul 26.

PMID:
24585830
15.

Dickeya solani sp. nov., a pectinolytic plant-pathogenic bacterium isolated from potato (Solanum tuberosum).

van der Wolf JM, Nijhuis EH, Kowalewska MJ, Saddler GS, Parkinson N, Elphinstone JG, Pritchard L, Toth IK, Lojkowska E, Potrykus M, Waleron M, de Vos P, Cleenwerck I, Pirhonen M, Garlant L, Hélias V, Pothier JF, Pflüger V, Duffy B, Tsror L, Manulis S.

Int J Syst Evol Microbiol. 2014 Mar;64(Pt 3):768-74. doi: 10.1099/ijs.0.052944-0. Epub 2013 Nov 13.

PMID:
24225027
16.

High frequency of copy number variations (CNVs) in the chromosome 11p15 region in patients with Beckwith-Wiedemann syndrome.

Baskin B, Choufani S, Chen YA, Shuman C, Parkinson N, Lemyre E, Micheil Innes A, Stavropoulos DJ, Ray PN, Weksberg R.

Hum Genet. 2014 Mar;133(3):321-30. doi: 10.1007/s00439-013-1379-z. Epub 2013 Oct 24.

PMID:
24154661
17.

Application of variable-number tandem-repeat typing to discriminate Ralstonia solanacearum strains associated with English watercourses and disease outbreaks.

Parkinson N, Bryant R, Bew J, Conyers C, Stones R, Alcock M, Elphinstone J.

Appl Environ Microbiol. 2013 Oct;79(19):6016-22. doi: 10.1128/AEM.01219-13. Epub 2013 Jul 26.

18.

Severe hypertriglyceridaemia in horses and ponies with endocrine disorders.

Dunkel B, Wilford SA, Parkinson NJ, Ward C, Smith P, Grahame L, Brazil T, Schott HC 2nd.

Equine Vet J. 2014 Jan;46(1):118-22. doi: 10.1111/evj.12089. Epub 2013 Jul 1.

PMID:
23663085
19.

Novel 9q34.11 gene deletions encompassing combinations of four Mendelian disease genes: STXBP1, SPTAN1, ENG, and TOR1A.

Campbell IM, Yatsenko SA, Hixson P, Reimschisel T, Thomas M, Wilson W, Dayal U, Wheless JW, Crunk A, Curry C, Parkinson N, Fishman L, Riviello JJ, Nowaczyk MJ, Zeesman S, Rosenfeld JA, Bejjani BA, Shaffer LG, Cheung SW, Lupski JR, Stankiewicz P, Scaglia F.

Genet Med. 2012 Oct;14(10):868-76. doi: 10.1038/gim.2012.65. Epub 2012 Jun 21.

20.

Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice.

Ghazi-Noori S, Froud KE, Mizielinska S, Powell C, Smidak M, Fernandez de Marco M, O'Malley C, Farmer M, Parkinson N, Fisher EM, Asante EA, Brandner S, Collinge J, Isaacs AM.

Brain. 2012 Mar;135(Pt 3):819-32. doi: 10.1093/brain/aws006.

PMID:
22366797
21.

CDKN1C mutations and genital anomalies.

Welsh HI, Stockley TL, Parkinson N, Ardinger HH.

Am J Med Genet A. 2012 Jan;158A(1):265. doi: 10.1002/ajmg.a.34388. Epub 2011 Dec 2. No abstract available.

PMID:
22140035
22.

Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA.

Parkinson NJ, Maslau S, Ferneyhough B, Zhang G, Gregory L, Buck D, Ragoussis J, Ponting CP, Fischer MD.

Genome Res. 2012 Jan;22(1):125-33. doi: 10.1101/gr.124016.111. Epub 2011 Nov 16.

23.

Molecular epidemiology of strangles outbreaks in the UK during 2010.

Parkinson NJ, Robin C, Newton JR, Slater J, Waller AS.

Vet Rec. 2011 Jun 25;168(25):666. doi: 10.1136/vr.d1485. Epub 2011 Jun 14.

PMID:
21672953
24.

Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.

Banks GT, Haas MA, Line S, Shepherd HL, Alqatari M, Stewart S, Rishal I, Philpott A, Kalmar B, Kuta A, Groves M, Parkinson N, Acevedo-Arozena A, Brandner S, Bannerman D, Greensmith L, Hafezparast M, Koltzenburg M, Deacon R, Fainzilber M, Fisher EM.

J Neurosci. 2011 Apr 6;31(14):5483-94. doi: 10.1523/JNEUROSCI.5244-10.2011.

25.

The novel PMCA2 pump mutation Tommy impairs cytosolic calcium clearance in hair cells and links to deafness in mice.

Bortolozzi M, Brini M, Parkinson N, Crispino G, Scimemi P, De Siati RD, Di Leva F, Parker A, Ortolano S, Arslan E, Brown SD, Carafoli E, Mammano F.

J Biol Chem. 2010 Nov 26;285(48):37693-703. doi: 10.1074/jbc.M110.170092. Epub 2010 Sep 8.

26.

Expression patterns of hormones, signaling molecules, and transcription factors during adenohypophysis development in the chick embryo.

Parkinson N, Collins MM, Dufresne L, Ryan AK.

Dev Dyn. 2010 Apr;239(4):1197-210. doi: 10.1002/dvdy.22250.

27.

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy.

Bäumer D, Lee S, Nicholson G, Davies JL, Parkinson NJ, Murray LM, Gillingwater TH, Ansorge O, Davies KE, Talbot K.

PLoS Genet. 2009 Dec;5(12):e1000773. doi: 10.1371/journal.pgen.1000773. Epub 2009 Dec 18.

28.

TARDBP in amyotrophic lateral sclerosis: identification of a novel variant but absence of copy number variation.

Bäumer D, Parkinson N, Talbot K.

J Neurol Neurosurg Psychiatry. 2009 Nov;80(11):1283-5. doi: 10.1136/jnnp.2008.166512.

PMID:
19864663
29.

Proposal of Xanthomonas translucens pv. pistaciae pv. nov., pathogenic to pistachio (Pistacia vera).

Giblot-Ducray D, Marefat A, Gillings MR, Parkinson NM, Bowman JP, Ophel-Keller K, Taylor C, Facelli E, Scott ES.

Syst Appl Microbiol. 2009 Dec;32(8):549-57. doi: 10.1016/j.syapm.2009.08.001. Epub 2009 Sep 13.

PMID:
19748753
30.

Analysis of the mouse mutant Cloth-ears shows a role for the voltage-gated sodium channel Scn8a in peripheral neural hearing loss.

Mackenzie FE, Parker A, Parkinson NJ, Oliver PL, Brooker D, Underhill P, Lukashkina VA, Lukashkin AN, Holmes C, Brown SD.

Genes Brain Behav. 2009 Oct;8(7):699-713. doi: 10.1111/j.1601-183X.2009.00514.x. Epub 2009 Jun 22.

31.

Dickeya species relatedness and clade structure determined by comparison of recA sequences.

Parkinson N, Stead D, Bew J, Heeney J, Tsror Lahkim L, Elphinstone J.

Int J Syst Evol Microbiol. 2009 Oct;59(Pt 10):2388-93. doi: 10.1099/ijs.0.009258-0. Epub 2009 Jul 20.

PMID:
19620370
32.

Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model.

Turner BJ, Parkinson NJ, Davies KE, Talbot K.

Neurobiol Dis. 2009 Jun;34(3):511-7. doi: 10.1016/j.nbd.2009.03.005. Epub 2009 Mar 28.

PMID:
19332122
33.

Phylogenetic structure of Xanthomonas determined by comparison of gyrB sequences.

Parkinson N, Cowie C, Heeney J, Stead D.

Int J Syst Evol Microbiol. 2009 Feb;59(Pt 2):264-74. doi: 10.1099/ijs.0.65825-0.

PMID:
19196764
34.

TDP-43 expression in mouse models of amyotrophic lateral sclerosis and spinal muscular atrophy.

Turner BJ, Bäumer D, Parkinson NJ, Scaber J, Ansorge O, Talbot K.

BMC Neurosci. 2008 Oct 28;9:104. doi: 10.1186/1471-2202-9-104.

35.

Plant-pathogenic bacteria as biological weapons - real threats?

Young JM, Allen C, Coutinho T, Denny T, Elphinstone J, Fegan M, Gillings M, Gottwald TR, Graham JH, Iacobellis NS, Janse JD, Jacques MA, Lopez MM, Morris CE, Parkinson N, Prior P, Pruvost O, Neto JR, Scortichini M, Takikawa Y, Upper CD.

Phytopathology. 2008 Oct;98(10):1060-5. doi: 10.1094/PHYTO-98-10-1060.

36.

4th UK spinal muscular atrophy (SMA) researchers network meeting.

Parkinson NJ.

Neuromuscul Disord. 2008 Apr;18(4):349-53. doi: 10.1016/j.nmd.2008.01.006. Epub 2008 Apr 8. No abstract available.

PMID:
18396402
37.

Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders.

Parkinson NJ, Baumer D, Rose-Morris A, Talbot K.

Neuromuscul Disord. 2008 May;18(5):394-7. doi: 10.1016/j.nmd.2008.03.003. Epub 2008 Apr 18.

PMID:
18395445
38.

Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.

Murray LM, Comley LH, Thomson D, Parkinson N, Talbot K, Gillingwater TH.

Hum Mol Genet. 2008 Apr 1;17(7):949-62. Epub 2007 Dec 8.

39.

Phylogenetic analysis of Xanthomonas species by comparison of partial gyrase B gene sequences.

Parkinson N, Aritua V, Heeney J, Cowie C, Bew J, Stead D.

Int J Syst Evol Microbiol. 2007 Dec;57(Pt 12):2881-7.

PMID:
18048743
40.

Detection of Xanthomonas fragariae and presumptive detection of Xanthomonas arboricola pv. fragariae, from strawberry leaves, by real-time PCR.

Weller SA, Beresford-Jones NJ, Hall J, Thwaites R, Parkinson N, Elphinstone JG.

J Microbiol Methods. 2007 Aug;70(2):379-83. Epub 2007 May 31.

PMID:
17588695
41.
42.

Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media.

Parkinson N, Hardisty-Hughes RE, Tateossian H, Tsai HT, Brooker D, Morse S, Lalane Z, MacKenzie F, Fray M, Glenister P, Woodward AM, Polley S, Barbaric I, Dear N, Hough TA, Hunter AJ, Cheeseman MT, Brown SD.

PLoS Genet. 2006 Oct 6;2(10):e149.

43.

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B).

Parkinson N, Ince PG, Smith MO, Highley R, Skibinski G, Andersen PM, Morrison KE, Pall HS, Hardiman O, Collinge J, Shaw PJ, Fisher EM; MRC Proteomics in ALS Study; FReJA Consortium.

Neurology. 2006 Sep 26;67(6):1074-7. Epub 2006 Jun 28.

PMID:
16807408
44.

The impact of treatment for gynecological cancer on health-related quality of life (HRQoL): a systematic review.

Jones GL, Ledger W, Bonnett TJ, Radley S, Parkinson N, Kennedy SH.

Am J Obstet Gynecol. 2006 Jan;194(1):26-42. Review.

PMID:
16389007
45.

Adenovirus-mediated p53 gene therapy in osteosarcoma cell lines: sensitization to cisplatin and doxorubicin.

Ganjavi H, Gee M, Narendran A, Parkinson N, Krishnamoorthy M, Freedman MH, Malkin D.

Cancer Gene Ther. 2006 Apr;13(4):415-9.

PMID:
16211088
46.

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia.

Skibinski G, Parkinson NJ, Brown JM, Chakrabarti L, Lloyd SL, Hummerich H, Nielsen JE, Hodges JR, Spillantini MG, Thusgaard T, Brandner S, Brun A, Rossor MN, Gade A, Johannsen P, Sørensen SA, Gydesen S, Fisher EM, Collinge J.

Nat Genet. 2005 Aug;37(8):806-8. Epub 2005 Jul 24.

PMID:
16041373
47.

Clinical nurse specialists and the psychosexual needs of patients with gynaecological cancer.

Parkinson N, Pratt H.

J Br Menopause Soc. 2005 Mar;11(1):33-5. Review.

PMID:
15814061
48.

A gene-driven ENU-based approach to generating an allelic series in any gene.

Quwailid MM, Hugill A, Dear N, Vizor L, Wells S, Horner E, Fuller S, Weedon J, McMath H, Woodman P, Edwards D, Campbell D, Rodger S, Carey J, Roberts A, Glenister P, Lalanne Z, Parkinson N, Coghill EL, McKeone R, Cox S, Willan J, Greenfield A, Keays D, Brady S, Spurr N, Gray I, Hunter J, Brown SD, Cox RD.

Mamm Genome. 2004 Aug;15(8):585-91.

PMID:
15457338
49.

Towards a comprehensive view of the primary structure of venom proteins from the parasitoid wasp Pimpla hypochondriaca.

Parkinson NM, Conyers C, Keen J, MacNicoll A, Smith I, Audsley N, Weaver R.

Insect Biochem Mol Biol. 2004 Jun;34(6):565-71.

PMID:
15147757
50.

The homeobox gene Emx2 underlies middle ear and inner ear defects in the deaf mouse mutant pardon.

Rhodes CR, Parkinson N, Tsai H, Brooker D, Mansell S, Spurr N, Hunter AJ, Steel KP, Brown SD.

J Neurocytol. 2003 Nov;32(9):1143-54.

PMID:
15044845

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