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Analysis of age-sex and deprivation stratified trends in assault deaths in Scotland (1974-2015) to identify age, period or cohort effects.

Parkinson J, Minton J, McCartney G.

BMJ Open. 2020 Feb 9;10(2):e030064. doi: 10.1136/bmjopen-2019-030064.


Complete structure of the chemosensory array core signalling unit in an E. coli minicell strain.

Burt A, Cassidy CK, Ames P, Bacia-Verloop M, Baulard M, Huard K, Luthey-Schulten Z, Desfosses A, Stansfeld PJ, Margolin W, Parkinson JS, Gutsche I.

Nat Commun. 2020 Feb 6;11(1):743. doi: 10.1038/s41467-020-14350-9.


Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review.

Shinjyo N, Parkinson J, Bell J, Katsuno T, Bligh A.

J Integr Med. 2020 Jan 16. pii: S2095-4964(20)30005-4. doi: 10.1016/j.joim.2020.01.004. [Epub ahead of print] Review.


N-Linked Surface Glycan Biosynthesis, Composition, Inhibition, and Function in Cnidarian-Dinoflagellate Symbiosis.

Tivey TR, Parkinson JE, Mandelare PE, Adpressa DA, Peng W, Dong X, Mechref Y, Weis VM, Loesgen S.

Microb Ecol. 2020 Jan 25. doi: 10.1007/s00248-020-01487-9. [Epub ahead of print]


Accumulation of genetic variants associated with immunity in the selective breeding of broilers.

Zou A, Nadeau K, Wang PW, Lee JY, Guttman DS, Sharif S, Korver DR, Brumell JH, Parkinson J.

BMC Genet. 2020 Jan 17;21(1):5. doi: 10.1186/s12863-020-0807-z.


Bis(phosphine)hydridorhodacarborane Derivatives of 1,1'-Bis(ortho-carborane) and Their Catalysis of Alkene Isomerization and the Hydrosilylation of Acetophenone.

Chan APY, Parkinson JA, Rosair GM, Welch AJ.

Inorg Chem. 2020 Feb 3;59(3):2011-2023. doi: 10.1021/acs.inorgchem.9b03351. Epub 2020 Jan 16.


Structure and dynamics of the E. coli chemotaxis core signaling complex by cryo-electron tomography and molecular simulations.

Cassidy CK, Himes BA, Sun D, Ma J, Zhao G, Parkinson JS, Stansfeld PJ, Luthey-Schulten Z, Zhang P.

Commun Biol. 2020 Jan 10;3(1):24. doi: 10.1038/s42003-019-0748-0.


Molecular and clonal evolution in recurrent metastatic gliosarcoma.

Anderson KJ, Tan AC, Parkinson J, Back M, Kastelan M, Newey A, Brewer J, Wheeler H, Hudson AL, Amin SB, Johnson KC, Barthel FP, Verhaak RGW, Khasraw M.

Cold Spring Harb Mol Case Stud. 2020 Feb 3;6(1). pii: a004671. doi: 10.1101/mcs.a004671. Print 2020 Feb.


Clinical and molecular evidence of accelerated ageing following very preterm birth.

Parkinson JRC, Emsley R, Adkins JLT, Longford N, Ozanne SE, Holmes E, Modi N.

Pediatr Res. 2019 Dec 7. doi: 10.1038/s41390-019-0709-9. [Epub ahead of print]


Point-of-use filters for prevention of health care-acquired Legionnaires' disease: Field evaluation of a new filter product and literature review.

Parkinson J, Baron JL, Hall B, Bos H, Racine P, Wagener MM, Stout JE.

Am J Infect Control. 2020 Feb;48(2):132-138. doi: 10.1016/j.ajic.2019.09.006. Epub 2019 Oct 25.


Investigation of the Factors That Dictate the Preferred Orientation of Lexitropsins in the Minor Groove of DNA.

Alniss HY, Witzel II, Semreen MH, Panda PK, Mishra YK, Ahuja R, Parkinson JA.

J Med Chem. 2019 Nov 27;62(22):10423-10440. doi: 10.1021/acs.jmedchem.9b01534. Epub 2019 Nov 8.


Under Elevated c-di-GMP in Escherichia coli, YcgR Alters Flagellar Motor Bias and Speed Sequentially, with Additional Negative Control of the Flagellar Regulon via the Adaptor Protein RssB.

Nieto V, Partridge JD, Severin GB, Lai RZ, Waters CM, Parkinson JS, Harshey RM.

J Bacteriol. 2019 Dec 6;202(1). pii: e00578-19. doi: 10.1128/JB.00578-19. Print 2019 Dec 6.


Metabolomic Profiling of the Immune Stimulatory Effect of Eicosenoids on PMA-Differentiated THP-1 Cells.

Alqarni AM, Dissanayake T, Nelson DJ, Parkinson JA, Dufton MJ, Ferro VA, Watson DG.

Vaccines (Basel). 2019 Oct 9;7(4). pii: E142. doi: 10.3390/vaccines7040142.


Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung.

Chenery AL, Alhallaf R, Agha Z, Ajendra J, Parkinson JE, Cooper MM, Chan BHK, Eichenberger RM, Dent LA, Robertson AAB, Kupz A, Brough D, Loukas A, Sutherland TE, Allen JE, Giacomin PR.

J Immunol. 2019 Nov 15;203(10):2724-2734. doi: 10.4049/jimmunol.1900640. Epub 2019 Oct 4.


Commensal gut microbiota can modulate adaptive immune responses in chickens vaccinated with whole inactivated avian influenza virus subtype H9N2.

Yitbarek A, Astill J, Hodgins DC, Parkinson J, Nagy É, Sharif S.

Vaccine. 2019 Oct 16;37(44):6640-6647. doi: 10.1016/j.vaccine.2019.09.046. Epub 2019 Sep 18.


Do age, period or cohort effects explain circulatory disease mortality trends, Scotland 1974-2015?

Parkinson J, Minton J, Bouttell J, Lewsey J, Shah A, McCartney G.

Heart. 2019 Sep 20. pii: heartjnl-2019-315029. doi: 10.1136/heartjnl-2019-315029. [Epub ahead of print]


Identification of a Kinase-Active CheA Conformation in Escherichia coli Chemoreceptor Signaling Complexes.

Piñas GE, Parkinson JS.

J Bacteriol. 2019 Nov 5;201(23). pii: e00543-19. doi: 10.1128/JB.00543-19. Print 2019 Dec 1.


Understanding how and why de-implementation works in health and care: research protocol for a realist synthesis of evidence.

Burton C, Williams L, Bucknall T, Edwards S, Fisher D, Hall B, Harris G, Jones P, Makin M, McBride A, Meacock R, Parkinson J, Rycroft-Malone J, Waring J.

Syst Rev. 2019 Aug 5;8(1):194. doi: 10.1186/s13643-019-1111-8.


Future challenges and new approaches: general discussion.

Afonso C, Chaux C, Davies AN, Delsuc MA, Fernandez Lima F, Gauchotte-Lindsay C, Giusti P, Goodacre R, Hawkes JA, Hertkorn N, Jansen JJ, Kew W, Kuhn S, Lubben A, McGill D, Nilsson M, Parkinson J, Rodgers RP, Rogers S, Schmitt-Kopplin P, Schoenmakers PJ, Shintu L, Soong R, Summerfield S, Surman A, Uhrín D, van der Hooft JJJ.

Faraday Discuss. 2019 Aug 15;218(0):505-523. doi: 10.1039/c9fd90046b. No abstract available.


Data mining and visualisation: general discussion.

Afonso C, Barrow MP, Davies AN, Delsuc MA, Ebbels T, Fernandez-Lima F, Gauchotte-Lindsay C, Giusti P, Goodacre R, Hertkorn N, Jansen JJ, Jones D, Kew W, Kuhn S, Le Guennec A, Lubben A, Parkinson J, Paša-Tolić L, Rogers S, Rudd TR, Schoenmakers PJ, Sidebottom P, Summerfield S, Tinnevelt GH, Trifirò G, Trygg J, van der Hooft JJJ.

Faraday Discuss. 2019 Aug 15;218(0):354-371. doi: 10.1039/C9FD90044F. No abstract available.


Considerations for maximizing the adaptive potential of restored coral populations in the western Atlantic.

Baums IB, Baker AC, Davies SW, Grottoli AG, Kenkel CD, Kitchen SA, Kuffner IB, LaJeunesse TC, Matz MV, Miller MW, Parkinson JE, Shantz AA.

Ecol Appl. 2019 Dec;29(8):e01978. doi: 10.1002/eap.1978. Epub 2019 Aug 19.


Conformational shifts in a chemoreceptor helical hairpin control kinase signaling in Escherichia coli.

Gao Q, Cheng A, Parkinson JS.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15651-15660. doi: 10.1073/pnas.1902521116. Epub 2019 Jul 17.


In Situ Conformational Changes of the Escherichia coli Serine Chemoreceptor in Different Signaling States.

Yang W, Cassidy CK, Ames P, Diebolder CA, Schulten K, Luthey-Schulten Z, Parkinson JS, Briegel A.

mBio. 2019 Jul 2;10(4). pii: e00973-19. doi: 10.1128/mBio.00973-19.


Effect of alcohol on the sense of agency in healthy humans.

De Pirro S, Lush P, Parkinson J, Duka T, Critchley HD, Badiani A.

Addict Biol. 2019 Jun 20:e12796. doi: 10.1111/adb.12796. [Epub ahead of print]


Inter-partner specificity limits the acquisition of thermotolerant symbionts in a model cnidarian-dinoflagellate symbiosis.

Gabay Y, Parkinson JE, Wilkinson SP, Weis VM, Davy SK.

ISME J. 2019 Oct;13(10):2489-2499. doi: 10.1038/s41396-019-0429-5. Epub 2019 Jun 11.


Sequence-Selective Minor Groove Recognition of a DNA Duplex Containing Synthetic Genetic Components.

Padroni G, Withers JM, Taladriz-Sender A, Reichenbach LF, Parkinson JA, Burley GA.

J Am Chem Soc. 2019 Jun 19;141(24):9555-9563. doi: 10.1021/jacs.8b12444. Epub 2019 Jun 4.


PopNetD3-A Network-Based Web Resource for Exploring Population Structure.

Zhang J, Parkinson J.

Genome Biol Evol. 2019 Jul 1;11(7):1730-1735. doi: 10.1093/gbe/evz100.


Comparison of pharmacokinetics and the exposure-response relationship of dapagliflozin between adolescent/young adult and adult patients with type 1 diabetes mellitus.

Busse D, Tang W, Scheerer M, Danne T, Biester T, Sokolov V, Boulton D, Parkinson J.

Br J Clin Pharmacol. 2019 Aug;85(8):1820-1828. doi: 10.1111/bcp.13981. Epub 2019 Jun 20.


Mushy-layer growth and convection, with application to sea ice.

Wells AJ, Hitchen JR, Parkinson JRG.

Philos Trans A Math Phys Eng Sci. 2019 Jun 3;377(2146):20180165. doi: 10.1098/rsta.2018.0165.


Reducing health inequalities trough digital options in mental health: A physician's perspective.

Taiminen HM, Saraniemi S, Joffe G, Stenberg JH, Parkinson J.

Health Mark Q. 2019 Apr-Jun;36(2):93-106. doi: 10.1080/07359683.2019.1575059. Epub 2019 Mar 23.


Focal radiation therapy for limited brain metastases is associated with high rates of local control and low subsequent whole brain radiation therapy.

Or M, Jayamanne D, Guo L, Stevens M, Parkinson J, Cook R, Little N, Back M.

ANZ J Surg. 2019 Apr;89(4):418-422. doi: 10.1111/ans.15040. Epub 2019 Mar 5.


Model-based characterization of the relationship between dapagliflozin systemic exposure and HbA1c response in patients with type 1 diabetes mellitus.

Parkinson J, Tang W, Åstrand M, Melin J, Ekholm E, Hamrén B, Boulton DW.

Diabetes Obes Metab. 2019 Jun;21(6):1381-1387. doi: 10.1111/dom.13664. Epub 2019 Mar 14.


Design and application of a novel two-amplicon approach for defining eukaryotic microbiota.

Popovic A, Bourdon C, Wang PW, Guttman DS, Voskuijl W, Grigg ME, Bandsma RHJ, Parkinson J.

Microbiome. 2018 Dec 20;6(1):228. doi: 10.1186/s40168-018-0612-3.


Exploring the insulin secretory properties of the PGD2-GPR44/DP2 axis in vitro and in a randomized phase-1 trial of type 2 diabetes patients.

Skrtic S, Tyrberg B, Broberg M, Ericsson H, Schnecke V, Kjaer M, Hompesch M, Andersson EM, Ryberg E, Aivazidis A, Wennberg Huldt C, Löfgren L, Morrow L, Parkinson J, Rydén-Bergsten T, Watkins E, Sörhede Winzell M.

PLoS One. 2018 Dec 17;13(12):e0208998. doi: 10.1371/journal.pone.0208998. eCollection 2018.


Urinary glucose excretion after dapagliflozin treatment: An exposure-response modelling comparison between Japanese and non-Japanese patients diagnosed with type 1 diabetes mellitus.

Sokolov V, Yakovleva T, Ueda S, Parkinson J, Boulton DW, Penland RC, Tang W.

Diabetes Obes Metab. 2018 Nov 19. doi: 10.1111/dom.13586. [Epub ahead of print]


Lactobacillus elicits a 'Marmite effect' on the chicken cecal microbiome.

Zou A, Sharif S, Parkinson J.

NPJ Biofilms Microbiomes. 2018 Nov 9;4:27. doi: 10.1038/s41522-018-0070-5. eCollection 2018.


Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues.

Aman K, Padroni G, Parkinson JA, Welte T, Burley GA.

Chemistry. 2019 Feb 21;25(11):2757-2763. doi: 10.1002/chem.201805338. Epub 2019 Jan 14.


Author Correction: Gut microbiota-mediated protection against influenza virus subtype H9N2 in chickens is associated with modulation of the innate responses.

Yitbarek A, Taha-Abdelaziz K, Hodgins DC, Read L, Nagy É, Weese JS, Caswell JL, Parkinson J, Sharif S.

Sci Rep. 2018 Oct 31;8(1):16367. doi: 10.1038/s41598-018-34065-8.


Face perception enhances insula and motor network reactivity in Tourette syndrome.

Rae CL, Polyanska L, Gould van Praag CD, Parkinson J, Bouyagoub S, Nagai Y, Seth AK, Harrison NA, Garfinkel SN, Critchley HD.

Brain. 2018 Nov 1;141(11):3249-3261. doi: 10.1093/brain/awy254.


Effect of Melittin on Metabolomic Profile and Cytokine Production in PMA-Differentiated THP-1 Cells.

Alqarni AM, Ferro VA, Parkinson JA, Dufton MJ, Watson DG.

Vaccines (Basel). 2018 Oct 13;6(4). pii: E72. doi: 10.3390/vaccines6040072.


Role of 18F-fluoro-ethyl-tyrosine Positron Emission Tomography in Investigation and Management of Suspected Gliomas.

Ibbett I, Schembri G, Cook R, Parkinson J.

World Neurosurg. 2019 Jan;121:e712-e715. doi: 10.1016/j.wneu.2018.09.194. Epub 2018 Oct 6.


Analyzing Metabolic Pathways in Microbiomes.

Adeolu M, Parkinson J, Xiong X.

Methods Mol Biol. 2018;1849:291-307. doi: 10.1007/978-1-4939-8728-3_18.


Characterization of Eukaryotic Microbiome Using 18S Amplicon Sequencing.

Popovic A, Parkinson J.

Methods Mol Biol. 2018;1849:29-48. doi: 10.1007/978-1-4939-8728-3_3.


FET PET in the evaluation of indeterminate brain lesions on MRI: Differentiating glioma from other non-neoplastic causes - A pilot study.

Chan DL, Hsiao E, Schembri G, Bailey DL, Roach PJ, Lee A, Jayamanne D, Ghasemzadeh M, Hayes A, Cook R, Parkinson J, Drummond JP, Ibbett I, Wheeler HR, Back M.

J Clin Neurosci. 2018 Dec;58:130-135. doi: 10.1016/j.jocn.2018.09.009. Epub 2018 Sep 19.


Gut microbiota-mediated protection against influenza virus subtype H9N2 in chickens is associated with modulation of the innate responses.

Yitbarek A, Taha-Abdelaziz K, Hodgins DC, Read L, Nagy É, Weese JS, Caswell JL, Parkinson J, Sharif S.

Sci Rep. 2018 Sep 4;8(1):13189. doi: 10.1038/s41598-018-31613-0. Erratum in: Sci Rep. 2018 Oct 31;8(1):16367.


Glioblastoma Recurrence Correlates With Increased APE1 and Polarization Toward an Immuno-Suppressive Microenvironment.

Hudson AL, Parker NR, Khong P, Parkinson JF, Dwight T, Ikin RJ, Zhu Y, Chen J, Wheeler HR, Howell VM.

Front Oncol. 2018 Aug 13;8:314. doi: 10.3389/fonc.2018.00314. eCollection 2018.


Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway conservation.

Swapna LS, Molinaro AM, Lindsay-Mosher N, Pearson BJ, Parkinson J.

Genome Biol. 2018 Aug 24;19(1):124. doi: 10.1186/s13059-018-1498-x.


Systematic Revision of Symbiodiniaceae Highlights the Antiquity and Diversity of Coral Endosymbionts.

LaJeunesse TC, Parkinson JE, Gabrielson PW, Jeong HJ, Reimer JD, Voolstra CR, Santos SR.

Curr Biol. 2018 Aug 20;28(16):2570-2580.e6. doi: 10.1016/j.cub.2018.07.008. Epub 2018 Aug 9.


A Fast and Robust Way to Estimate Overlap of Niches, and Draw Inference.

Parkinson JH, Kutil R, Kuppler J, Junker RR, Trutschnig W, Bathke AC.

Int J Biostat. 2018 Jun 15;14(2). pii: /j/ijb.2018.14.issue-2/ijb-2017-0028/ijb-2017-0028.xml. doi: 10.1515/ijb-2017-0028.


Subtle Differences in Symbiont Cell Surface Glycan Profiles Do Not Explain Species-Specific Colonization Rates in a Model Cnidarian-Algal Symbiosis.

Parkinson JE, Tivey TR, Mandelare PE, Adpressa DA, Loesgen S, Weis VM.

Front Microbiol. 2018 May 1;9:842. doi: 10.3389/fmicb.2018.00842. eCollection 2018.

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