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Items: 1 to 50 of 300

1.

Utility of TERT Promoter Mutations for Cutaneous Primary Melanoma Diagnosis.

Thomas NE, Edmiston SN, Tsai YS, Parker JS, Googe PB, Busam KJ, Scott GA, Zedek DC, Parrish EA, Hao H, Slater NA, Pearlstein MV, Frank JS, Kuan PF, Ollila DW, Conway K.

Am J Dermatopathol. 2018 Sep 11. doi: 10.1097/DAD.0000000000001259. [Epub ahead of print]

PMID:
30211730
2.

Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes With Previous Radial Keratotomy.

Parker JS, Parker JS, Melles GRJ.

Cornea. 2018 Aug 22. doi: 10.1097/ICO.0000000000001719. [Epub ahead of print]

PMID:
30157047
3.

A functional riboSNitch in the 3'UTR of FKBP5 alters microRNA-320a binding efficiency and mediates vulnerability to chronic posttraumatic pain.

Linnstaedt SD, Riker KD, Rueckeis CA, Kutchko KM, Lackey L, McCarthy KR, Tsai YH, Parker JS, Kurz MC, Hendry PL, Lewandowski C, Datner E, Pearson C, O'Neil B, Domeier R, Kaushik S, Laederach A, McLean SA.

J Neurosci. 2018 Aug 27. pii: 3458-17. doi: 10.1523/JNEUROSCI.3458-17.2018. [Epub ahead of print]

PMID:
30150364
4.

Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma.

Smith CC, Beckermann KE, Bortone DS, de Cubas AA, Bixby LM, Lee SJ, Panda A, Ganesan S, Bhanot G, Wallen EM, Milowsky MI, Kim WY, Rathmell WK, Swanstrom R, Parker JS, Serody JS, Selitsky SR, Vincent BG.

J Clin Invest. 2018 Aug 23. pii: 121476. doi: 10.1172/JCI121476. [Epub ahead of print]

5.

Integrated Analysis of RNA and DNA from the Phase III Trial CALGB 40601 Identifies Predictors of Response to Trastuzumab-Based Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer.

Tanioka M, Fan C, Parker JS, Hoadley KA, Hu Z, Li Y, Hyslop TM, Pitcher BN, Soloway MG, Spears PA, Henry LN, Tolaney S, Dang CT, Krop IE, Harris LN, Berry DA, Mardis ER, Winer EP, Hudis CA, Carey LA, Perou CM.

Clin Cancer Res. 2018 Jul 23. doi: 10.1158/1078-0432.CCR-17-3431. [Epub ahead of print]

PMID:
30037817
6.

VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma.

Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, Liu XD, Jonasch E, Xie L, Chen X, Yao X, Teh BT, Tan P, Zheng X, Li M, Lawrence C, Fan J, Geng J, Liu X, Hu L, Wang J, Liao C, Hong K, Zurlo G, Parker JS, Auman JT, Perou CM, Rathmell WK, Kim WY, Kirschner MW, Kaelin WG Jr, Baldwin AS, Zhang Q.

Science. 2018 Jul 20;361(6399):290-295. doi: 10.1126/science.aap8411.

PMID:
30026228
7.

Identification of gene expression levels in primary melanoma associated with clinically meaningful characteristics.

Gorlov I, Orlow I, Ringelberg C, Hernando E, Ernstoff MS, Cheng C, Her S, Parker JS, Thompson CL, Gerstenblith MR, Berwick M, Amos C.

Melanoma Res. 2018 Oct;28(5):380-389. doi: 10.1097/CMR.0000000000000473.

PMID:
29975213
8.

LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases.

Van Swearingen AED, Siegel MB, Deal AM, Sambade MJ, Hoyle A, Hayes DN, Jo H, Little P, Dees EC, Muss H, Jolly T, Zagar TM, Patel N, Miller CR, Parker JS, Smith JK, Fisher J, Shah N, Nabell L, Nanda R, Dillon P, Abramson V, Carey LA, Anders CK.

Breast Cancer Res Treat. 2018 Jun 25. doi: 10.1007/s10549-018-4852-5. [Epub ahead of print]

PMID:
29938395
9.

The Need for a Combat Casualty Care Research Program and Trauma Registry for Military Working Dogs.

Orman JA, Parker JS, Stockinger ZT, Nemelka KW; Military Working Dog Trauma Registry Strategic Planning Group.

Mil Med. 2018 Jun 15. doi: 10.1093/milmed/usy141. [Epub ahead of print] No abstract available.

PMID:
29912454
10.

Identification of clonal hematopoiesis mutations in solid tumor patients undergoing unpaired next-generation sequencing assays.

Coombs CC, Gillis NK, Tan X, Berg JS, Ball MC, Balasis ME, Montgomery ND, Bolton K, Parker JS, Mesa TE, Yoder SJ, Hayward MC, Patel NM, Richards KL, Walko CM, Knepper TC, Soper JT, Weiss J, Grilley-Olson JE, Kim WY, Earp S, Levine R, Papaemmanuil E, Zehir A, Hayes DN, Padron E.

Clin Cancer Res. 2018 Jun 4. pii: clincanres.1201.2018. doi: 10.1158/1078-0432.CCR-18-1201. [Epub ahead of print]

PMID:
29866652
11.

Validity of Bowman layer transplantation for keratoconus: visual performance at 5-7 years.

Zygoura V, Birbal RS, van Dijk K, Parker JS, Baydoun L, Dapena I, Melles GRJ.

Acta Ophthalmol. 2018 May 31. doi: 10.1111/aos.13745. [Epub ahead of print] No abstract available.

PMID:
29855169
12.

Multiple Origins and Nested Cycles of Hybridization Result in High Tetraploid Diversity in the Monocot Prospero.

Jang TS, Parker JS, Emadzade K, Temsch EM, Leitch AR, Weiss-Schneeweiss H.

Front Plant Sci. 2018 Apr 6;9:433. doi: 10.3389/fpls.2018.00433. eCollection 2018.

13.

SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma.

Chiang YC, Park IY, Terzo EA, Tripathi DN, Mason FM, Fahey CC, Karki M, Shuster CB, Sohn BH, Chowdhury P, Powell RT, Ohi R, Tsai YS, de Cubas AA, Khan A, Davis IJ, Strahl BD, Parker JS, Dere R, Walker CL, Rathmell WK.

Cancer Res. 2018 Jun 15;78(12):3135-3146. doi: 10.1158/0008-5472.CAN-17-3460. Epub 2018 May 3.

PMID:
29724720
14.

Meta-analysis of airway epithelium gene expression in asthma.

Tsai YH, Parker JS, Yang IV, Kelada SNP.

Eur Respir J. 2018 May 17;51(5). pii: 1701962. doi: 10.1183/13993003.01962-2017. Print 2018 May.

PMID:
29650561
15.

Gene expression-phenotype associations in adults with eosinophilic esophagitis.

Dellon ES, Selitsky SR, Genta RM, Lash RH, Parker JS.

Dig Liver Dis. 2018 Aug;50(8):804-811. doi: 10.1016/j.dld.2018.03.021. Epub 2018 Mar 27.

PMID:
29628359
16.

The Immune Landscape of Cancer.

Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CE; Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich L.

Immunity. 2018 Apr 17;48(4):812-830.e14. doi: 10.1016/j.immuni.2018.03.023. Epub 2018 Apr 5.

17.

Outcomes of Hemi-Descemet Membrane Endothelial Keratoplasty for Fuchs Endothelial Corneal Dystrophy.

Birbal RS, Hsien S, Zygoura V, Parker JS, Ham L, van Dijk K, Dapena I, Baydoun L, Melles GRJ.

Cornea. 2018 Jul;37(7):854-858. doi: 10.1097/ICO.0000000000001578.

PMID:
29557816
18.

Disease burden and conditioning regimens in ASCT1221, a randomized phase II trial in children with juvenile myelomonocytic leukemia: A Children's Oncology Group study.

Dvorak CC, Satwani P, Stieglitz E, Cairo MS, Dang H, Pei Q, Gao Y, Wall D, Mazor T, Olshen AB, Parker JS, Kahwash S, Hirsch B, Raimondi S, Patel N, Skeens M, Cooper T, Mehta PA, Grupp SA, Loh ML.

Pediatr Blood Cancer. 2018 Jul;65(7):e27034. doi: 10.1002/pbc.27034. Epub 2018 Mar 12.

PMID:
29528181
19.

Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer.

Siegel MB, He X, Hoadley KA, Hoyle A, Pearce JB, Garrett AL, Kumar S, Moylan VJ, Brady CM, Van Swearingen AE, Marron D, Gupta GP, Thorne LB, Kieran N, Livasy C, Mardis ER, Parker JS, Chen M, Anders CK, Carey LA, Perou CM.

J Clin Invest. 2018 Apr 2;128(4):1371-1383. doi: 10.1172/JCI96153. Epub 2018 Feb 26.

20.

The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells.

Xu B, Cai L, Butler JM, Chen D, Lu X, Allison DF, Lu R, Rafii S, Parker JS, Zheng D, Wang GG.

Stem Cell Reports. 2018 Mar 13;10(3):675-683. doi: 10.1016/j.stemcr.2018.01.020. Epub 2018 Feb 15.

21.

Bowman layer transplantation: 5-year results.

van Dijk K, Parker JS, Baydoun L, Ilyas A, Dapena I, Groeneveld-van Beek EA, Melles GRJ.

Graefes Arch Clin Exp Ophthalmol. 2018 Jun;256(6):1151-1158. doi: 10.1007/s00417-018-3927-7. Epub 2018 Feb 14.

PMID:
29445872
22.

Publisher Correction: Combating subclonal evolution of resistant cancer phenotypes.

Brady SW, McQuerry JA, Qiao Y, Piccolo SR, Shrestha G, Jenkins DF, Layer RM, Pedersen BS, Miller RH, Esch A, Selitsky SR, Parker JS, Anderson LA, Dalley BK, Factor RE, Reddy CB, Boltax JP, Li DY, Moos PJ, Gray JW, Heiser LM, Buys SS, Cohen AL, Johnson WE, Quinlan AR, Marth G, Werner TL, Bild AH.

Nat Commun. 2018 Feb 5;9(1):572. doi: 10.1038/s41467-017-02383-6.

23.

Conserved Surface Residues on the Feline Calicivirus Capsid Are Essential for Interaction with Its Receptor Feline Junctional Adhesion Molecule A (fJAM-A).

Lu Z, Ledgerwood ED, Hinchman MM, Dick R, Parker JSL.

J Virol. 2018 Mar 28;92(8). pii: e00035-18. doi: 10.1128/JVI.00035-18. Print 2018 Apr 15.

PMID:
29386293
24.

Reply: Management of Descemet Membrane Detachment After Forceps Birth Injury.

Parker JS, Parker JS, Melles GRJ.

Cornea. 2018 Apr;37(4):e24-e25. doi: 10.1097/ICO.0000000000001514. No abstract available.

PMID:
29346130
25.

Trypan blue-assisted microinvasive glaucoma surgery.

Parker JS, Parker A, Parker JS.

J Cataract Refract Surg. 2017 Dec;43(12):1613. doi: 10.1016/j.jcrs.2017.10.031. No abstract available.

PMID:
29335109
26.

Respiratory disease in ball pythons (Python regius) experimentally infected with ball python nidovirus.

Hoon-Hanks LL, Layton ML, Ossiboff RJ, Parker JSL, Dubovi EJ, Stenglein MD.

Virology. 2018 Apr;517:77-87. doi: 10.1016/j.virol.2017.12.008. Epub 2018 Jan 10.

27.

Identification of Germline Variants in Tumor Genomic Sequencing Analysis.

Montgomery ND, Selitsky SR, Patel NM, Hayes DN, Parker JS, Weck KE.

J Mol Diagn. 2018 Jan;20(1):123-125. doi: 10.1016/j.jmoldx.2017.09.008.

PMID:
29249243
28.

Enhancing Next-Generation Sequencing-Guided Cancer Care Through Cognitive Computing.

Patel NM, Michelini VV, Snell JM, Balu S, Hoyle AP, Parker JS, Hayward MC, Eberhard DA, Salazar AH, McNeillie P, Xu J, Huettner CS, Koyama T, Utro F, Rhrissorrakrai K, Norel R, Bilal E, Royyuru A, Parida L, Earp HS, Grilley-Olson JE, Hayes DN, Harvey SJ, Sharpless NE, Kim WY.

Oncologist. 2018 Feb;23(2):179-185. doi: 10.1634/theoncologist.2017-0170. Epub 2017 Nov 20.

29.

Subtyping sub-Saharan esophageal squamous cell carcinoma by comprehensive molecular analysis.

Liu W, Snell JM, Jeck WR, Hoadley KA, Wilkerson MD, Parker JS, Patel N, Mlombe YB, Mulima G, Liomba NG, Wolf LL, Shores CG, Gopal S, Sharpless NE.

JCI Insight. 2017 Nov 16;2(22). pii: 98457. doi: 10.1172/jci.insight.98457. [Epub ahead of print] No abstract available.

30.

Combating subclonal evolution of resistant cancer phenotypes.

Brady SW, McQuerry JA, Qiao Y, Piccolo SR, Shrestha G, Jenkins DF, Layer RM, Pedersen BS, Miller RH, Esch A, Selitsky SR, Parker JS, Anderson LA, Dalley BK, Factor RE, Reddy CB, Boltax JP, Li DY, Moos PJ, Gray JW, Heiser LM, Buys SS, Cohen AL, Johnson WE, Quinlan AR, Marth G, Werner TL, Bild AH.

Nat Commun. 2017 Nov 1;8(1):1231. doi: 10.1038/s41467-017-01174-3. Erratum in: Nat Commun. 2018 Feb 5;9(1):572.

31.

Sequence analysis of feline immunoglobulin mRNAs and the development of a felinized monoclonal antibody specific to feline panleukopenia virus.

Lu Z, Tallmadge RL, Callaway HM, Felippe MJB, Parker JSL.

Sci Rep. 2017 Oct 5;7(1):12713. doi: 10.1038/s41598-017-12725-5.

32.

Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer.

Taylor NA, Vick SC, Iglesia MD, Brickey WJ, Midkiff BR, McKinnon KP, Reisdorf S, Anders CK, Carey LA, Parker JS, Perou CM, Vincent BG, Serody JS.

J Clin Invest. 2017 Sep 1;127(9):3472-3483. doi: 10.1172/JCI90499. Epub 2017 Aug 21.

33.

Metabolic reprogramming underlies metastatic potential in an obesity-responsive murine model of metastatic triple negative breast cancer.

O'Flanagan CH, Rossi EL, McDonell SB, Chen X, Tsai YH, Parker JS, Usary J, Perou CM, Hursting SD.

NPJ Breast Cancer. 2017 Jul 17;3:26. doi: 10.1038/s41523-017-0027-5. eCollection 2017.

34.

MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma.

Bailey ST, Smith AM, Kardos J, Wobker SE, Wilson HL, Krishnan B, Saito R, Lee HJ, Zhang J, Eaton SC, Williams LA, Manocha U, Peters DJ, Pan X, Carroll TJ, Felsher DW, Walter V, Zhang Q, Parker JS, Yeh JJ, Moffitt RA, Leung JY, Kim WY.

Nat Commun. 2017 Jun 8;8:15770. doi: 10.1038/ncomms15770.

35.

Technical feasibility of isolated Bowman layer graft preparation by femtosecond laser: a pilot study.

Parker JS, Huls F, Cooper E, Graves P, Groeneveld-van Beek EA, Lie J, Melles GRJ.

Eur J Ophthalmol. 2017 Nov 8;27(6):675-677. doi: 10.5301/ejo.5000990. Epub 2017 May 26.

PMID:
28574133
36.

Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations.

Chang J, Tan W, Ling Z, Xi R, Shao M, Chen M, Luo Y, Zhao Y, Liu Y, Huang X, Xia Y, Hu J, Parker JS, Marron D, Cui Q, Peng L, Chu J, Li H, Du Z, Han Y, Tan W, Liu Z, Zhan Q, Li Y, Mao W, Wu C, Lin D.

Nat Commun. 2017 May 26;8:15290. doi: 10.1038/ncomms15290.

37.

A B-Cell Gene Signature Correlates With the Extent of Gluten-Induced Intestinal Injury in Celiac Disease.

Garber ME, Saldanha A, Parker JS, Jones WD, Kaukinen K, Laurila K, Lähdeaho ML, Khatri P, Khosla C, Adelman DC, Mäki M.

Cell Mol Gastroenterol Hepatol. 2017 Jan 28;4(1):1-17. doi: 10.1016/j.jcmgh.2017.01.011. eCollection 2017 Jul.

38.

An integrated parity-time symmetric wavelength-tunable single-mode microring laser.

Liu W, Li M, Guzzon RS, Norberg EJ, Parker JS, Lu M, Coldren LA, Yao J.

Nat Commun. 2017 May 12;8:15389. doi: 10.1038/ncomms15389.

39.

Immune-Related Gene Expression Profiling After PD-1 Blockade in Non-Small Cell Lung Carcinoma, Head and Neck Squamous Cell Carcinoma, and Melanoma.

Prat A, Navarro A, Paré L, Reguart N, Galván P, Pascual T, Martínez A, Nuciforo P, Comerma L, Alos L, Pardo N, Cedrés S, Fan C, Parker JS, Gaba L, Victoria I, Viñolas N, Vivancos A, Arance A, Felip E.

Cancer Res. 2017 Jul 1;77(13):3540-3550. doi: 10.1158/0008-5472.CAN-16-3556. Epub 2017 May 9.

40.

Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer.

Van Swearingen AED, Sambade MJ, Siegel MB, Sud S, McNeill RS, Bevill SM, Chen X, Bash RE, Mounsey L, Golitz BT, Santos C, Deal A, Parker JS, Rashid N, Miller CR, Johnson GL, Anders CK.

Neuro Oncol. 2017 Oct 19;19(11):1481-1493. doi: 10.1093/neuonc/nox052.

PMID:
28486691
41.

SynthEx: a synthetic-normal-based DNA sequencing tool for copy number alteration detection and tumor heterogeneity profiling.

Silva GO, Siegel MB, Mose LE, Parker JS, Sun W, Perou CM, Chen M.

Genome Biol. 2017 Apr 8;18(1):66. doi: 10.1186/s13059-017-1193-3.

42.

An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity.

Beak J, Huang W, Parker JS, Hicks ST, Patterson C, Simpson PC, Ma A, Jin J, Jensen BC.

JACC Basic Transl Sci. 2017 Feb;2(1):39-53. doi: 10.1016/j.jacbts.2016.10.006.

43.

A Gene Expression Panel is Accurate for Diagnosis and Monitoring Treatment of Eosinophilic Esophagitis in Adults.

Dellon ES, Veerappan R, Selitsky SR, Parker JS, Higgins LL, Beitia R, Genta RM, Lash RH.

Clin Transl Gastroenterol. 2017 Feb 9;8(2):e74. doi: 10.1038/ctg.2017.2.

44.

Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer.

Mehta GA, Parker JS, Silva GO, Hoadley KA, Perou CM, Gatza ML.

Breast Cancer Res Treat. 2017 Apr;162(3):439-450. doi: 10.1007/s10549-017-4139-2. Epub 2017 Feb 7.

45.

Tumor-homing cytotoxic human induced neural stem cells for cancer therapy.

Bagó JR, Okolie O, Dumitru R, Ewend MG, Parker JS, Werff RV, Underhill TM, Schmid RS, Miller CR, Hingtgen SD.

Sci Transl Med. 2017 Feb 1;9(375). pii: eaah6510. doi: 10.1126/scitranslmed.aah6510.

PMID:
28148846
46.

Boston Type 1 Keratoprosthesis: Visual Outcomes, Device Retention, and Complications.

Parker JS, Morris RE, Rooney DM, Parker JS.

Cornea. 2017 Apr;36(4):e13-e14. doi: 10.1097/ICO.0000000000001154. No abstract available.

PMID:
28129294
47.

Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex.

Zawistowski JS, Bevill SM, Goulet DR, Stuhlmiller TJ, Beltran AS, Olivares-Quintero JF, Singh D, Sciaky N, Parker JS, Rashid NU, Chen X, Duncan JS, Whittle MC, Angus SP, Velarde SH, Golitz BT, He X, Santos C, Darr DB, Gallagher K, Graves LM, Perou CM, Carey LA, Earp HS, Johnson GL.

Cancer Discov. 2017 Mar;7(3):302-321. doi: 10.1158/2159-8290.CD-16-0653. Epub 2017 Jan 20.

48.

Correction: Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases.

Hoadley KA, Siegel MB, Kanchi KL, Miller CA, Ding L, Zhao W, He X, Parker JS, Wendl MC, Fulton RS, Demeter RT, Wilson RK, Carey LA, Perou CM, Mardis ER.

PLoS Med. 2017 Jan 9;14(1):e1002222. doi: 10.1371/journal.pmed.1002222. eCollection 2017 Jan.

49.

Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue.

Snowden E, Porter W, Hahn F, Ferguson M, Tong F, Parker JS, Middlebrook A, Ghanekar S, Dillmore WS, Blaesius R.

Mol Cancer Res. 2017 Apr;15(4):429-438. doi: 10.1158/1541-7786.MCR-16-0286-T. Epub 2016 Dec 30.

50.

Exceptional Chemotherapy Response in Metastatic Colorectal Cancer Associated With Hyper-Indel-Hypermutated Cancer Genome and Comutation of POLD1 and MLH1.

Sharma MR, Auman JT, Patel NM, Grilley-Olson JE, Zhao X, Moschos SJ, Parker JS, Yin X, Hayward MC, Polite BN, Marangon E, Posocco B, Toffoli G, Hayes DN, Innocenti F.

JCO Precis Oncol. 2017;2017. doi: 10.1200/PO.16.00015. Epub 2017 Apr 27.

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