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Items: 1 to 50 of 339

1.

The Immune Landscape of Cancer.

Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS; Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I.

Immunity. 2019 Aug 20;51(2):411-412. doi: 10.1016/j.immuni.2019.08.004. No abstract available.

PMID:
31433971
2.

Perceived difficulties and barriers to uptake of Descemet's membrane endothelial keratoplasty among surgeons.

Zafar S, Parker JS, de Kort C, Melles G, Sikder S.

Clin Ophthalmol. 2019 Jun 21;13:1055-1061. doi: 10.2147/OPTH.S212871. eCollection 2019.

3.

Reply.

Dockery PW, Joubert KP, Parker JS, Parker JS.

Cornea. 2019 Jul 16. doi: 10.1097/ICO.0000000000002079. [Epub ahead of print] No abstract available.

PMID:
31385919
4.

Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons' Data.

Gao GF, Parker JS, Reynolds SM, Silva TC, Wang LB, Zhou W, Akbani R, Bailey M, Balu S, Berman BP, Brooks D, Chen H, Cherniack AD, Demchok JA, Ding L, Felau I, Gaheen S, Gerhard DS, Heiman DI, Hernandez KM, Hoadley KA, Jayasinghe R, Kemal A, Knijnenburg TA, Laird PW, Mensah MKA, Mungall AJ, Robertson AG, Shen H, Tarnuzzer R, Wang Z, Wyczalkowski M, Yang L, Zenklusen JC, Zhang Z; Genomic Data Analysis Network, Liang H, Noble MS.

Cell Syst. 2019 Jul 24;9(1):24-34.e10. doi: 10.1016/j.cels.2019.06.006.

5.

Macrocyclisation and functionalisation of unprotected peptides via divinyltriazine cysteine stapling.

Robertson NS, Walsh SJ, Fowler E, Yoshida M, Rowe SM, Wu Y, Sore HF, Parker JS, Spring DR.

Chem Commun (Camb). 2019 Aug 7;55(64):9499-9502. doi: 10.1039/c9cc05042f.

PMID:
31328756
6.

Cleavable linkers in antibody-drug conjugates.

Bargh JD, Isidro-Llobet A, Parker JS, Spring DR.

Chem Soc Rev. 2019 Aug 12;48(16):4361-4374. doi: 10.1039/c8cs00676h. Review.

PMID:
31294429
7.

Mammalian orthoreovirus Infection is Enhanced in Cells Pre-Treated with Sodium Arsenite.

Lutz MM 4th, Worth MP, Hinchman MM, Parker JSL, Ledgerwood ED.

Viruses. 2019 Jun 18;11(6). pii: E563. doi: 10.3390/v11060563.

8.

Breast cancer PAM50 signature: correlation and concordance between RNA-Seq and digital multiplexed gene expression technologies in a triple negative breast cancer series.

Picornell AC, Echavarria I, Alvarez E, López-Tarruella S, Jerez Y, Hoadley K, Parker JS, Del Monte-Millán M, Ramos-Medina R, Gayarre J, Ocaña I, Cebollero M, Massarrah T, Moreno F, García Saenz JA, Gómez Moreno H, Ballesteros A, Ruiz Borrego M, Perou CM, Martin M.

BMC Genomics. 2019 Jun 3;20(1):452. doi: 10.1186/s12864-019-5849-0.

9.

Prognostic value of B cells in cutaneous melanoma.

Selitsky SR, Mose LE, Smith CC, Chai S, Hoadley KA, Dittmer DP, Moschos SJ, Parker JS, Vincent BG.

Genome Med. 2019 May 28;11(1):36. doi: 10.1186/s13073-019-0647-5.

10.

Rapid Clearance Profile of Plasma Circulating Tumor HPV Type 16 DNA during Chemoradiotherapy Correlates with Disease Control in HPV-Associated Oropharyngeal Cancer.

Chera BS, Kumar S, Beaty BT, Marron D, Jefferys S, Green R, Goldman EC, Amdur R, Sheets N, Dagan R, Hayes DN, Weiss J, Grilley-Olson JE, Zanation A, Hackman T, Blumberg JM, Patel S, Weissler M, Tan XM, Parker JS, Mendenhall W, Gupta GP.

Clin Cancer Res. 2019 Aug 1;25(15):4682-4690. doi: 10.1158/1078-0432.CCR-19-0211. Epub 2019 May 14.

PMID:
31088830
11.

HER2-enriched subtype and ERBB2 expression in HER2-positive breast cancer treated with dual HER2 blockade.

Prat A, Pascual T, De Angelis C, Gutierrez C, Llombart-Cussac A, Wang T, Cortés J, Rexer B, Paré L, Forero A, Wolff AC, Morales S, Adamo B, Brasó-Maristany F, Vidal M, Veeraraghavan J, Krop I, Galván P, Pavlick AC, Bermejo B, Izquierdo M, Rodrik-Outmezguine V, Reis-Filho JS, Hilsenbeck SG, Oliveira M, Dieci MV, Griguolo G, Fasani R, Nuciforo P, Parker JS, Conte P, Schiff R, Guarneri V, Osborne CK, Rimawi MF.

J Natl Cancer Inst. 2019 Apr 30. pii: djz042. doi: 10.1093/jnci/djz042. [Epub ahead of print]

PMID:
31037288
12.

Use of intraoperative anterior segment optical coherence tomography for Bowman layer transplantation.

Tong CM, Parker JS, Dockery PW, Birbal RS, Melles GRJ.

Acta Ophthalmol. 2019 Apr 23. doi: 10.1111/aos.14104. [Epub ahead of print] No abstract available.

PMID:
31016838
13.

Tracking Veterinary Students Who Aspire to Careers in Science.

McGregor DD, Fraser DR, Parker JSL.

J Vet Med Educ. 2019 Mar 28:1-6. doi: 10.3138/jvme.0118-010r1. [Epub ahead of print]

PMID:
30920950
14.

Are Descemet membrane ruptures the root cause of corneal hydrops in keratoconic eyes?

Parker JS, Birbal RS, van Dijk K, Oellerich S, Dapena I, Melles GRJ.

Am J Ophthalmol. 2019 Mar 21. pii: S0002-9394(19)30123-0. doi: 10.1016/j.ajo.2019.03.017. [Epub ahead of print]

PMID:
30905722
15.

Bacteroides Spp. Blebitis, Keratitis, and Endophthalmitis Following Uncomplicated Trabeculectomy.

Parker JS, Dockery PW, Parker JS, Crosson JN, Kilpatrick D, Samuels B.

J Glaucoma. 2019 Jul;28(7):e118-e120. doi: 10.1097/IJG.0000000000001235.

PMID:
30855413
16.

Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1.

McCann JV, Xiao L, Kim DJ, Khan OF, Kowalski PS, Anderson DG, Pecot CV, Azam SH, Parker JS, Tsai YS, Wolberg AS, Turner SD, Tatsumi K, Mackman N, Dudley AC.

J Clin Invest. 2019 Mar 11;130:1654-1670. doi: 10.1172/JCI123106. eCollection 2019 Mar 11.

17.

RNA-Sequencing of Umbilical Cord Blood to Investigate Spontaneous Preterm Birth: A Pilot Study.

Vora NL, Parker JS, Mieckowski PA, Smeester L, Fry RC, Boggess KA.

AJP Rep. 2019 Jan;9(1):e60-e66. doi: 10.1055/s-0039-1678717. Epub 2019 Mar 7.

18.

I-Boost: an integrative boosting approach for predicting survival time with multiple genomics platforms.

Wong KY, Fan C, Tanioka M, Parker JS, Nobel AB, Zeng D, Lin DY, Perou CM.

Genome Biol. 2019 Mar 7;20(1):52. doi: 10.1186/s13059-019-1640-4.

19.

Separation of breast cancer and organ microenvironment transcriptomes in metastases.

Alzubi MA, Turner TH, Olex AL, Sohal SS, Tobin NP, Recio SG, Bergh J, Hatschek T, Parker JS, Sartorius CA, Perou CM, Dozmorov MG, Harrell JC.

Breast Cancer Res. 2019 Mar 6;21(1):36. doi: 10.1186/s13058-019-1123-2.

20.

Dynamic changes in lung responses after single and repeated exposures to cigarette smoke in mice.

Engle ML, Monk JN, Jania CM, Martin JR, Gomez JC, Dang H, Parker JS, Doerschuk CM.

PLoS One. 2019 Feb 28;14(2):e0212866. doi: 10.1371/journal.pone.0212866. eCollection 2019.

21.

Corneal ulceration associated with Nivolumab use.

Parker JS, Feagin W, Wang C, Heersink M, Parker JS.

Am J Ophthalmol Case Rep. 2019 Feb 7;14:26-27. doi: 10.1016/j.ajoc.2019.01.013. eCollection 2019 Jun.

22.

Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR.

Chem Sci. 2018 Dec 13;10(2):633-634. doi: 10.1039/c8sc90248h. eCollection 2019 Jan 14.

23.

A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR.

Chem Sci. 2018 Nov 9;10(3):694-700. doi: 10.1039/c8sc04645j. eCollection 2019 Jan 21. Erratum in: Chem Sci. 2018 Dec 13;10(2):633-634.

24.

Cells exhibiting strong p16 INK4a promoter activation in vivo display features of senescence.

Liu JY, Souroullas GP, Diekman BO, Krishnamurthy J, Hall BM, Sorrentino JA, Parker JS, Sessions GA, Gudkov AV, Sharpless NE.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2603-2611. doi: 10.1073/pnas.1818313116. Epub 2019 Jan 25.

25.

The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma.

Zhao X, Little P, Hoyle AP, Pegna GJ, Hayward MC, Ivanova A, Parker JS, Marron DL, Soloway MG, Jo H, Salazar AH, Papakonstantinou MP, Bouchard DM, Jefferys SR, Hoadley KA, Ollila DW, Frank JS, Thomas NE, Googe PB, Ezzell AJ, Collichio FA, Lee CB, Earp HS, Sharpless NE, Hugo W, Wilmott JS, Quek C, Waddell N, Johansson PA, Thompson JF, Hayward NK, Mann GJ, Lo RS, Johnson DB, Scolyer RA, Hayes DN, Moschos SJ.

Front Oncol. 2019 Jan 4;8:584. doi: 10.3389/fonc.2018.00584. eCollection 2018.

26.

Improved Indel Detection in DNA and RNA via Realignment with ABRA2.

Mose LE, Perou CM, Parker JS.

Bioinformatics. 2019 Jan 15. doi: 10.1093/bioinformatics/btz033. [Epub ahead of print]

PMID:
30649250
27.

An Alternative Focus for Route Design for the Synthesis of Antibody-Drug Conjugate Payloads.

Tiberghien AC, Howard PW, Goundry WRF, McCormick M, Parker JS.

J Org Chem. 2019 Apr 19;84(8):4830-4836. doi: 10.1021/acs.joc.8b02876. Epub 2019 Jan 11.

PMID:
30602115
28.

PAM50 Molecular Intrinsic Subtypes in the Nurses' Health Study Cohorts.

Kensler KH, Sankar VN, Wang J, Zhang X, Rubadue CA, Baker GM, Parker JS, Hoadley KA, Stancu AL, Pyle ME, Collins LC, Hunter DJ, Eliassen AH, Hankinson SE, Tamimi RM, Heng YJ.

Cancer Epidemiol Biomarkers Prev. 2019 Apr;28(4):798-806. doi: 10.1158/1055-9965.EPI-18-0863. Epub 2018 Dec 27.

PMID:
30591591
29.

Simultaneous multiplexed amplicon sequencing and transcriptome profiling in single cells.

Saikia M, Burnham P, Keshavjee SH, Wang MFZ, Heyang M, Moral-Lopez P, Hinchman MM, Danko CG, Parker JSL, De Vlaminck I.

Nat Methods. 2019 Jan;16(1):59-62. doi: 10.1038/s41592-018-0259-9. Epub 2018 Dec 17.

30.

Identification of a Robust Methylation Classifier for Cutaneous Melanoma Diagnosis.

Conway K, Edmiston SN, Parker JS, Kuan PF, Tsai YH, Groben PA, Zedek DC, Scott GA, Parrish EA, Hao H, Pearlstein MV, Frank JS, Carson CC, Wilkerson MD, Zhao X, Slater NA, Moschos SJ, Ollila DW, Thomas NE.

J Invest Dermatol. 2019 Jun;139(6):1349-1361. doi: 10.1016/j.jid.2018.11.024. Epub 2018 Dec 6.

PMID:
30529013
31.

Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes With a Glaucoma Drainage Device.

Birbal RS, Tong CM, Dapena I, Parker JS, Parker JS, Oellerich S, Melles GRJ.

Am J Ophthalmol. 2019 Mar;199:150-158. doi: 10.1016/j.ajo.2018.11.014. Epub 2018 Nov 28.

PMID:
30502334
32.

A pLOT of Viral Persistence.

Parker JSL.

Cell Host Microbe. 2018 Nov 14;24(5):618-619. doi: 10.1016/j.chom.2018.10.010.

PMID:
30439337
33.

Synthesis and cycloaddition reactions of strained alkynes derived from 2,2'-dihydroxy-1,1'-biaryls.

Mistry A, Knighton RC, Forshaw S, Dualeh Z, Parker JS, Wills M.

Org Biomol Chem. 2018 Nov 28;16(46):8965-8975. doi: 10.1039/c8ob01768a.

PMID:
30417909
34.

A Monolayer of Primary Colonic Epithelium Generated on a Scaffold with a Gradient of Stiffness for Drug Transport Studies.

Gunasekara DB, Speer J, Wang Y, Nguyen DL, Reed MI, Smiddy NM, Parker JS, Fallon JK, Smith PC, Sims CE, Magness ST, Allbritton NL.

Anal Chem. 2018 Nov 20;90(22):13331-13340. doi: 10.1021/acs.analchem.8b02845. Epub 2018 Oct 30.

PMID:
30350627
35.

Manual mid-stromal dissection as a low risk procedure to stabilize mild to moderate progressive keratoconus.

Birbal RS, van Dijk K, Parker JS, Otten H, Belmoukadim M, Ham L, Baydoun L, Dapena I, Melles GRJ.

Eye Vis (Lond). 2018 Oct 11;5:26. doi: 10.1186/s40662-018-0121-2. eCollection 2018.

36.

Epstein-Barr Virus-Positive Cancers Show Altered B-Cell Clonality.

Selitsky SR, Marron D, Mose LE, Parker JS, Dittmer DP.

mSystems. 2018 Sep 25;3(5). pii: e00081-18. doi: 10.1128/mSystems.00081-18. eCollection 2018 Sep-Oct.

37.

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer.

Cai L, Tsai YH, Wang P, Wang J, Li D, Fan H, Zhao Y, Bareja R, Lu R, Wilson EM, Sboner A, Whang YE, Zheng D, Parker JS, Earp HS, Wang GG.

Mol Cell. 2018 Oct 18;72(2):341-354.e6. doi: 10.1016/j.molcel.2018.08.029. Epub 2018 Sep 27.

PMID:
30270106
38.

Male breast cancer: a disease distinct from female breast cancer.

Gucalp A, Traina TA, Eisner JR, Parker JS, Selitsky SR, Park BH, Elias AD, Baskin-Bey ES, Cardoso F.

Breast Cancer Res Treat. 2019 Jan;173(1):37-48. doi: 10.1007/s10549-018-4921-9. Epub 2018 Sep 28. Review.

PMID:
30267249
39.

Euchromatic Supernumerary Chromosomal Segments-Remnants of Ongoing Karyotype Restructuring in the Prospero autumnale Complex?

Jang TS, Parker JS, Weiss-Schneeweiss H.

Genes (Basel). 2018 Sep 27;9(10). pii: E468. doi: 10.3390/genes9100468.

40.

Utility of TERT Promoter Mutations for Cutaneous Primary Melanoma Diagnosis.

Thomas NE, Edmiston SN, Tsai YS, Parker JS, Googe PB, Busam KJ, Scott GA, Zedek DC, Parrish EA, Hao H, Slater NA, Pearlstein MV, Frank JS, Kuan PF, Ollila DW, Conway K.

Am J Dermatopathol. 2019 Apr;41(4):264-272. doi: 10.1097/DAD.0000000000001259.

PMID:
30211730
41.

Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes With Previous Radial Keratotomy.

Parker JS, Parker JS, Melles GRJ.

Cornea. 2018 Nov;37(11):1351-1354. doi: 10.1097/ICO.0000000000001719.

PMID:
30157047
42.

A Functional riboSNitch in the 3' Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain.

Linnstaedt SD, Riker KD, Rueckeis CA, Kutchko KM, Lackey L, McCarthy KR, Tsai YH, Parker JS, Kurz MC, Hendry PL, Lewandowski C, Datner E, Pearson C, O'Neil B, Domeier R, Kaushik S, Laederach A, McLean SA.

J Neurosci. 2018 Sep 26;38(39):8407-8420. doi: 10.1523/JNEUROSCI.3458-17.2018. Epub 2018 Aug 27.

43.

Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma.

Smith CC, Beckermann KE, Bortone DS, De Cubas AA, Bixby LM, Lee SJ, Panda A, Ganesan S, Bhanot G, Wallen EM, Milowsky MI, Kim WY, Rathmell WK, Swanstrom R, Parker JS, Serody JS, Selitsky SR, Vincent BG.

J Clin Invest. 2018 Nov 1;128(11):4804-4820. doi: 10.1172/JCI121476. Epub 2018 Oct 2.

44.

Integrated Analysis of RNA and DNA from the Phase III Trial CALGB 40601 Identifies Predictors of Response to Trastuzumab-Based Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer.

Tanioka M, Fan C, Parker JS, Hoadley KA, Hu Z, Li Y, Hyslop TM, Pitcher BN, Soloway MG, Spears PA, Henry LN, Tolaney S, Dang CT, Krop IE, Harris LN, Berry DA, Mardis ER, Winer EP, Hudis CA, Carey LA, Perou CM.

Clin Cancer Res. 2018 Nov 1;24(21):5292-5304. doi: 10.1158/1078-0432.CCR-17-3431. Epub 2018 Jul 23.

PMID:
30037817
45.

VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma.

Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, Liu XD, Jonasch E, Xie L, Chen X, Yao X, Teh BT, Tan P, Zheng X, Li M, Lawrence C, Fan J, Geng J, Liu X, Hu L, Wang J, Liao C, Hong K, Zurlo G, Parker JS, Auman JT, Perou CM, Rathmell WK, Kim WY, Kirschner MW, Kaelin WG Jr, Baldwin AS, Zhang Q.

Science. 2018 Jul 20;361(6399):290-295. doi: 10.1126/science.aap8411.

46.

Identification of gene expression levels in primary melanoma associated with clinically meaningful characteristics.

Gorlov I, Orlow I, Ringelberg C, Hernando E, Ernstoff MS, Cheng C, Her S, Parker JS, Thompson CL, Gerstenblith MR, Berwick M, Amos C.

Melanoma Res. 2018 Oct;28(5):380-389. doi: 10.1097/CMR.0000000000000473.

PMID:
29975213
47.

LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases.

Van Swearingen AED, Siegel MB, Deal AM, Sambade MJ, Hoyle A, Hayes DN, Jo H, Little P, Dees EC, Muss H, Jolly T, Zagar TM, Patel N, Miller CR, Parker JS, Smith JK, Fisher J, Shah N, Nabell L, Nanda R, Dillon P, Abramson V, Carey LA, Anders CK.

Breast Cancer Res Treat. 2018 Oct;171(3):637-648. doi: 10.1007/s10549-018-4852-5. Epub 2018 Jun 25.

PMID:
29938395
48.

The Need for a Combat Casualty Care Research Program and Trauma Registry for Military Working Dogs.

Orman JA, Parker JS, Stockinger ZT, Nemelka KW; Military Working Dog Trauma Registry Strategic Planning Group.

Mil Med. 2018 Nov 1;183(11-12):258-260. doi: 10.1093/milmed/usy141. No abstract available.

PMID:
29912454
49.

Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays.

Coombs CC, Gillis NK, Tan X, Berg JS, Ball M, Balasis ME, Montgomery ND, Bolton KL, Parker JS, Mesa TE, Yoder SJ, Hayward MC, Patel NM, Richards KL, Walko CM, Knepper TC, Soper JT, Weiss J, Grilley-Olson JE, Kim WY, Earp HS 3rd, Levine RL, Papaemmanuil E, Zehir A, Hayes DN, Padron E.

Clin Cancer Res. 2018 Dec 1;24(23):5918-5924. doi: 10.1158/1078-0432.CCR-18-1201. Epub 2018 Jun 4.

PMID:
29866652
50.

Validity of Bowman layer transplantation for keratoconus: visual performance at 5-7 years.

Zygoura V, Birbal RS, van Dijk K, Parker JS, Baydoun L, Dapena I, Melles GRJ.

Acta Ophthalmol. 2018 Nov;96(7):e901-e902. doi: 10.1111/aos.13745. Epub 2018 May 31. No abstract available.

PMID:
29855169

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