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Items: 1 to 50 of 346

1.

Genetic determinants of cellular addiction to DNA polymerase theta.

Feng W, Simpson DA, Carvajal-Garcia J, Price BA, Kumar RJ, Mose LE, Wood RD, Rashid N, Purvis JE, Parker JS, Ramsden DA, Gupta GP.

Nat Commun. 2019 Sep 19;10(1):4286. doi: 10.1038/s41467-019-12234-1.

2.

Histone deacetylase 11 inhibition promotes breast cancer metastasis from lymph nodes.

Leslie PL, Chao YL, Tsai YH, Ghosh SK, Porrello A, Van Swearingen AED, Harrison EB, Cooley BC, Parker JS, Carey LA, Pecot CV.

Nat Commun. 2019 Sep 13;10(1):4192. doi: 10.1038/s41467-019-12222-5.

3.

Machine-Learning Prediction of Tumor Antigen Immunogenicity in the Selection of Therapeutic Epitopes.

Smith CC, Chai S, Washington AR, Lee SJ, Landoni E, Field K, Garness J, Bixby LM, Selitsky SR, Parker JS, Savoldo B, Serody JS, Vincent BG.

Cancer Immunol Res. 2019 Oct;7(10):1591-1604. doi: 10.1158/2326-6066.CIR-19-0155. Epub 2019 Sep 12.

PMID:
31515258
4.

A functional role for the cancer disparity-linked genes, CRYβB2 and CRYβB2P1, in the promotion of breast cancer.

Barrow MA, Martin ME, Coffey A, Andrews PL, Jones GS, Reaves DK, Parker JS, Troester MA, Fleming JM.

Breast Cancer Res. 2019 Sep 11;21(1):105. doi: 10.1186/s13058-019-1191-3.

5.

Comment on: "Cytomegalovirus Corneal Endotheliitis After Descemet Membrane Endothelial Keratoplasty".

Dockery PW, Joubert KP, Parker JS, Parker JS.

Cornea. 2019 Oct;38(10):e48. doi: 10.1097/ICO.0000000000002079. No abstract available.

PMID:
31498245
6.

Reply to a Comment: Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes With a Glaucoma Drainage Device.

Birbal RS, Tong CM, Dapena I, Parker JS, Parker JS, Oellerich S, Melles GRJ.

Am J Ophthalmol. 2019 Aug 27. pii: S0002-9394(19)30183-7. doi: 10.1016/j.ajo.2019.04.009. [Epub ahead of print] No abstract available.

PMID:
31470978
7.

Standardized versus research-based PAM50 intrinsic subtyping of breast cancer.

Prat A, Parker JS.

Clin Transl Oncol. 2019 Aug 21. doi: 10.1007/s12094-019-02203-x. [Epub ahead of print] No abstract available.

PMID:
31435878
8.

The Immune Landscape of Cancer.

Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS; Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I.

Immunity. 2019 Aug 20;51(2):411-412. doi: 10.1016/j.immuni.2019.08.004. No abstract available.

9.

Perceived difficulties and barriers to uptake of Descemet's membrane endothelial keratoplasty among surgeons.

Zafar S, Parker JS, de Kort C, Melles G, Sikder S.

Clin Ophthalmol. 2019 Jun 21;13:1055-1061. doi: 10.2147/OPTH.S212871. eCollection 2019.

10.

Reply.

Dockery PW, Joubert KP, Parker JS, Parker JS.

Cornea. 2019 Jul 16. doi: 10.1097/ICO.0000000000002079. [Epub ahead of print] No abstract available.

PMID:
31385919
11.

Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons' Data.

Gao GF, Parker JS, Reynolds SM, Silva TC, Wang LB, Zhou W, Akbani R, Bailey M, Balu S, Berman BP, Brooks D, Chen H, Cherniack AD, Demchok JA, Ding L, Felau I, Gaheen S, Gerhard DS, Heiman DI, Hernandez KM, Hoadley KA, Jayasinghe R, Kemal A, Knijnenburg TA, Laird PW, Mensah MKA, Mungall AJ, Robertson AG, Shen H, Tarnuzzer R, Wang Z, Wyczalkowski M, Yang L, Zenklusen JC, Zhang Z; Genomic Data Analysis Network, Liang H, Noble MS.

Cell Syst. 2019 Jul 24;9(1):24-34.e10. doi: 10.1016/j.cels.2019.06.006.

12.

Macrocyclisation and functionalisation of unprotected peptides via divinyltriazine cysteine stapling.

Robertson NS, Walsh SJ, Fowler E, Yoshida M, Rowe SM, Wu Y, Sore HF, Parker JS, Spring DR.

Chem Commun (Camb). 2019 Aug 7;55(64):9499-9502. doi: 10.1039/c9cc05042f.

PMID:
31328756
13.

Cleavable linkers in antibody-drug conjugates.

Bargh JD, Isidro-Llobet A, Parker JS, Spring DR.

Chem Soc Rev. 2019 Aug 12;48(16):4361-4374. doi: 10.1039/c8cs00676h. Review.

PMID:
31294429
14.

Mammalian orthoreovirus Infection is Enhanced in Cells Pre-Treated with Sodium Arsenite.

Lutz MM 4th, Worth MP, Hinchman MM, Parker JSL, Ledgerwood ED.

Viruses. 2019 Jun 18;11(6). pii: E563. doi: 10.3390/v11060563.

15.

Breast cancer PAM50 signature: correlation and concordance between RNA-Seq and digital multiplexed gene expression technologies in a triple negative breast cancer series.

Picornell AC, Echavarria I, Alvarez E, López-Tarruella S, Jerez Y, Hoadley K, Parker JS, Del Monte-Millán M, Ramos-Medina R, Gayarre J, Ocaña I, Cebollero M, Massarrah T, Moreno F, García Saenz JA, Gómez Moreno H, Ballesteros A, Ruiz Borrego M, Perou CM, Martin M.

BMC Genomics. 2019 Jun 3;20(1):452. doi: 10.1186/s12864-019-5849-0.

16.

Prognostic value of B cells in cutaneous melanoma.

Selitsky SR, Mose LE, Smith CC, Chai S, Hoadley KA, Dittmer DP, Moschos SJ, Parker JS, Vincent BG.

Genome Med. 2019 May 28;11(1):36. doi: 10.1186/s13073-019-0647-5.

17.

Rapid Clearance Profile of Plasma Circulating Tumor HPV Type 16 DNA during Chemoradiotherapy Correlates with Disease Control in HPV-Associated Oropharyngeal Cancer.

Chera BS, Kumar S, Beaty BT, Marron D, Jefferys S, Green R, Goldman EC, Amdur R, Sheets N, Dagan R, Hayes DN, Weiss J, Grilley-Olson JE, Zanation A, Hackman T, Blumberg JM, Patel S, Weissler M, Tan XM, Parker JS, Mendenhall W, Gupta GP.

Clin Cancer Res. 2019 Aug 1;25(15):4682-4690. doi: 10.1158/1078-0432.CCR-19-0211. Epub 2019 May 14.

PMID:
31088830
18.

HER2-enriched subtype and ERBB2 expression in HER2-positive breast cancer treated with dual HER2 blockade.

Prat A, Pascual T, De Angelis C, Gutierrez C, Llombart-Cussac A, Wang T, Cortés J, Rexer B, Paré L, Forero A, Wolff AC, Morales S, Adamo B, Brasó-Maristany F, Vidal M, Veeraraghavan J, Krop I, Galván P, Pavlick AC, Bermejo B, Izquierdo M, Rodrik-Outmezguine V, Reis-Filho JS, Hilsenbeck SG, Oliveira M, Dieci MV, Griguolo G, Fasani R, Nuciforo P, Parker JS, Conte P, Schiff R, Guarneri V, Osborne CK, Rimawi MF.

J Natl Cancer Inst. 2019 Apr 30. pii: djz042. doi: 10.1093/jnci/djz042. [Epub ahead of print]

PMID:
31037288
19.

Use of intraoperative anterior segment optical coherence tomography for Bowman layer transplantation.

Tong CM, Parker JS, Dockery PW, Birbal RS, Melles GRJ.

Acta Ophthalmol. 2019 Nov;97(7):e1031-e1032. doi: 10.1111/aos.14104. Epub 2019 Apr 23. No abstract available.

PMID:
31016838
20.

Tracking Veterinary Students Who Aspire to Careers in Science.

McGregor DD, Fraser DR, Parker JSL.

J Vet Med Educ. 2019 Mar 28:1-6. doi: 10.3138/jvme.0118-010r1. [Epub ahead of print]

PMID:
30920950
21.

Are Descemet Membrane Ruptures the Root Cause of Corneal Hydrops in Keratoconic Eyes?

Parker JS, Birbal RS, van Dijk K, Oellerich S, Dapena I, Melles GRJ.

Am J Ophthalmol. 2019 Sep;205:147-152. doi: 10.1016/j.ajo.2019.03.017. Epub 2019 Mar 22.

PMID:
30905722
22.

Bacteroides Spp. Blebitis, Keratitis, and Endophthalmitis Following Uncomplicated Trabeculectomy.

Parker JS, Dockery PW, Parker JS, Crosson JN, Kilpatrick D, Samuels B.

J Glaucoma. 2019 Jul;28(7):e118-e120. doi: 10.1097/IJG.0000000000001235.

PMID:
30855413
23.

Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1.

McCann JV, Xiao L, Kim DJ, Khan OF, Kowalski PS, Anderson DG, Pecot CV, Azam SH, Parker JS, Tsai YS, Wolberg AS, Turner SD, Tatsumi K, Mackman N, Dudley AC.

J Clin Invest. 2019 Mar 11;130:1654-1670. doi: 10.1172/JCI123106. eCollection 2019 Mar 11.

24.

RNA-Sequencing of Umbilical Cord Blood to Investigate Spontaneous Preterm Birth: A Pilot Study.

Vora NL, Parker JS, Mieckowski PA, Smeester L, Fry RC, Boggess KA.

AJP Rep. 2019 Jan;9(1):e60-e66. doi: 10.1055/s-0039-1678717. Epub 2019 Mar 7.

25.

I-Boost: an integrative boosting approach for predicting survival time with multiple genomics platforms.

Wong KY, Fan C, Tanioka M, Parker JS, Nobel AB, Zeng D, Lin DY, Perou CM.

Genome Biol. 2019 Mar 7;20(1):52. doi: 10.1186/s13059-019-1640-4.

26.

Separation of breast cancer and organ microenvironment transcriptomes in metastases.

Alzubi MA, Turner TH, Olex AL, Sohal SS, Tobin NP, Recio SG, Bergh J, Hatschek T, Parker JS, Sartorius CA, Perou CM, Dozmorov MG, Harrell JC.

Breast Cancer Res. 2019 Mar 6;21(1):36. doi: 10.1186/s13058-019-1123-2.

27.

Dynamic changes in lung responses after single and repeated exposures to cigarette smoke in mice.

Engle ML, Monk JN, Jania CM, Martin JR, Gomez JC, Dang H, Parker JS, Doerschuk CM.

PLoS One. 2019 Feb 28;14(2):e0212866. doi: 10.1371/journal.pone.0212866. eCollection 2019.

28.

Corneal ulceration associated with Nivolumab use.

Parker JS, Feagin W, Wang C, Heersink M, Parker JS.

Am J Ophthalmol Case Rep. 2019 Feb 7;14:26-27. doi: 10.1016/j.ajoc.2019.01.013. eCollection 2019 Jun.

29.

Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR.

Chem Sci. 2018 Dec 13;10(2):633-634. doi: 10.1039/c8sc90248h. eCollection 2019 Jan 14.

30.

A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR.

Chem Sci. 2018 Nov 9;10(3):694-700. doi: 10.1039/c8sc04645j. eCollection 2019 Jan 21. Erratum in: Chem Sci. 2018 Dec 13;10(2):633-634.

31.

Cells exhibiting strong p16 INK4a promoter activation in vivo display features of senescence.

Liu JY, Souroullas GP, Diekman BO, Krishnamurthy J, Hall BM, Sorrentino JA, Parker JS, Sessions GA, Gudkov AV, Sharpless NE.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2603-2611. doi: 10.1073/pnas.1818313116. Epub 2019 Jan 25.

32.

The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma.

Zhao X, Little P, Hoyle AP, Pegna GJ, Hayward MC, Ivanova A, Parker JS, Marron DL, Soloway MG, Jo H, Salazar AH, Papakonstantinou MP, Bouchard DM, Jefferys SR, Hoadley KA, Ollila DW, Frank JS, Thomas NE, Googe PB, Ezzell AJ, Collichio FA, Lee CB, Earp HS, Sharpless NE, Hugo W, Wilmott JS, Quek C, Waddell N, Johansson PA, Thompson JF, Hayward NK, Mann GJ, Lo RS, Johnson DB, Scolyer RA, Hayes DN, Moschos SJ.

Front Oncol. 2019 Jan 4;8:584. doi: 10.3389/fonc.2018.00584. eCollection 2018.

33.

Improved indel detection in DNA and RNA via realignment with ABRA2.

Mose LE, Perou CM, Parker JS.

Bioinformatics. 2019 Sep 1;35(17):2966-2973. doi: 10.1093/bioinformatics/btz033.

34.

An Alternative Focus for Route Design for the Synthesis of Antibody-Drug Conjugate Payloads.

Tiberghien AC, Howard PW, Goundry WRF, McCormick M, Parker JS.

J Org Chem. 2019 Apr 19;84(8):4830-4836. doi: 10.1021/acs.joc.8b02876. Epub 2019 Jan 11.

PMID:
30602115
35.

PAM50 Molecular Intrinsic Subtypes in the Nurses' Health Study Cohorts.

Kensler KH, Sankar VN, Wang J, Zhang X, Rubadue CA, Baker GM, Parker JS, Hoadley KA, Stancu AL, Pyle ME, Collins LC, Hunter DJ, Eliassen AH, Hankinson SE, Tamimi RM, Heng YJ.

Cancer Epidemiol Biomarkers Prev. 2019 Apr;28(4):798-806. doi: 10.1158/1055-9965.EPI-18-0863. Epub 2018 Dec 27.

PMID:
30591591
36.

Simultaneous multiplexed amplicon sequencing and transcriptome profiling in single cells.

Saikia M, Burnham P, Keshavjee SH, Wang MFZ, Heyang M, Moral-Lopez P, Hinchman MM, Danko CG, Parker JSL, De Vlaminck I.

Nat Methods. 2019 Jan;16(1):59-62. doi: 10.1038/s41592-018-0259-9. Epub 2018 Dec 17.

37.

Identification of a Robust Methylation Classifier for Cutaneous Melanoma Diagnosis.

Conway K, Edmiston SN, Parker JS, Kuan PF, Tsai YH, Groben PA, Zedek DC, Scott GA, Parrish EA, Hao H, Pearlstein MV, Frank JS, Carson CC, Wilkerson MD, Zhao X, Slater NA, Moschos SJ, Ollila DW, Thomas NE.

J Invest Dermatol. 2019 Jun;139(6):1349-1361. doi: 10.1016/j.jid.2018.11.024. Epub 2018 Dec 6.

PMID:
30529013
38.

Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes With a Glaucoma Drainage Device.

Birbal RS, Tong CM, Dapena I, Parker JS, Parker JS, Oellerich S, Melles GRJ.

Am J Ophthalmol. 2019 Mar;199:150-158. doi: 10.1016/j.ajo.2018.11.014. Epub 2018 Nov 28.

PMID:
30502334
39.

A pLOT of Viral Persistence.

Parker JSL.

Cell Host Microbe. 2018 Nov 14;24(5):618-619. doi: 10.1016/j.chom.2018.10.010.

PMID:
30439337
40.

Synthesis and cycloaddition reactions of strained alkynes derived from 2,2'-dihydroxy-1,1'-biaryls.

Mistry A, Knighton RC, Forshaw S, Dualeh Z, Parker JS, Wills M.

Org Biomol Chem. 2018 Nov 28;16(46):8965-8975. doi: 10.1039/c8ob01768a.

PMID:
30417909
41.

A Monolayer of Primary Colonic Epithelium Generated on a Scaffold with a Gradient of Stiffness for Drug Transport Studies.

Gunasekara DB, Speer J, Wang Y, Nguyen DL, Reed MI, Smiddy NM, Parker JS, Fallon JK, Smith PC, Sims CE, Magness ST, Allbritton NL.

Anal Chem. 2018 Nov 20;90(22):13331-13340. doi: 10.1021/acs.analchem.8b02845. Epub 2018 Oct 30.

PMID:
30350627
42.

Manual mid-stromal dissection as a low risk procedure to stabilize mild to moderate progressive keratoconus.

Birbal RS, van Dijk K, Parker JS, Otten H, Belmoukadim M, Ham L, Baydoun L, Dapena I, Melles GRJ.

Eye Vis (Lond). 2018 Oct 11;5:26. doi: 10.1186/s40662-018-0121-2. eCollection 2018.

43.

Epstein-Barr Virus-Positive Cancers Show Altered B-Cell Clonality.

Selitsky SR, Marron D, Mose LE, Parker JS, Dittmer DP.

mSystems. 2018 Sep 25;3(5). pii: e00081-18. doi: 10.1128/mSystems.00081-18. eCollection 2018 Sep-Oct.

44.

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer.

Cai L, Tsai YH, Wang P, Wang J, Li D, Fan H, Zhao Y, Bareja R, Lu R, Wilson EM, Sboner A, Whang YE, Zheng D, Parker JS, Earp HS, Wang GG.

Mol Cell. 2018 Oct 18;72(2):341-354.e6. doi: 10.1016/j.molcel.2018.08.029. Epub 2018 Sep 27.

45.

Male breast cancer: a disease distinct from female breast cancer.

Gucalp A, Traina TA, Eisner JR, Parker JS, Selitsky SR, Park BH, Elias AD, Baskin-Bey ES, Cardoso F.

Breast Cancer Res Treat. 2019 Jan;173(1):37-48. doi: 10.1007/s10549-018-4921-9. Epub 2018 Sep 28. Review.

PMID:
30267249
46.

Euchromatic Supernumerary Chromosomal Segments-Remnants of Ongoing Karyotype Restructuring in the Prospero autumnale Complex?

Jang TS, Parker JS, Weiss-Schneeweiss H.

Genes (Basel). 2018 Sep 27;9(10). pii: E468. doi: 10.3390/genes9100468.

47.

Utility of TERT Promoter Mutations for Cutaneous Primary Melanoma Diagnosis.

Thomas NE, Edmiston SN, Tsai YS, Parker JS, Googe PB, Busam KJ, Scott GA, Zedek DC, Parrish EA, Hao H, Slater NA, Pearlstein MV, Frank JS, Kuan PF, Ollila DW, Conway K.

Am J Dermatopathol. 2019 Apr;41(4):264-272. doi: 10.1097/DAD.0000000000001259.

PMID:
30211730
48.

Clinical Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes With Previous Radial Keratotomy.

Parker JS, Parker JS, Melles GRJ.

Cornea. 2018 Nov;37(11):1351-1354. doi: 10.1097/ICO.0000000000001719.

PMID:
30157047
49.

A Functional riboSNitch in the 3' Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain.

Linnstaedt SD, Riker KD, Rueckeis CA, Kutchko KM, Lackey L, McCarthy KR, Tsai YH, Parker JS, Kurz MC, Hendry PL, Lewandowski C, Datner E, Pearson C, O'Neil B, Domeier R, Kaushik S, Laederach A, McLean SA.

J Neurosci. 2018 Sep 26;38(39):8407-8420. doi: 10.1523/JNEUROSCI.3458-17.2018. Epub 2018 Aug 27.

50.

Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma.

Smith CC, Beckermann KE, Bortone DS, De Cubas AA, Bixby LM, Lee SJ, Panda A, Ganesan S, Bhanot G, Wallen EM, Milowsky MI, Kim WY, Rathmell WK, Swanstrom R, Parker JS, Serody JS, Selitsky SR, Vincent BG.

J Clin Invest. 2018 Nov 1;128(11):4804-4820. doi: 10.1172/JCI121476. Epub 2018 Oct 2.

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