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Items: 1 to 50 of 399


Health Researchers' Use of Social Media: Scoping Review.

Dol J, Tutelman PR, Chambers CT, Barwick M, Drake EK, Parker JA, Parker R, Benchimol EI, George RB, Witteman HO.

J Med Internet Res. 2019 Nov 13;21(11):e13687. doi: 10.2196/13687. Review.


Pleiotropic Effects of mTOR and Autophagy During Development and Aging.

Schmeisser K, Parker JA.

Front Cell Dev Biol. 2019 Sep 11;7:192. doi: 10.3389/fcell.2019.00192. eCollection 2019. Review.


The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis.

Bose P, Tremblay E, Maois C, Narasimhan V, Armstrong GAB, Liao M, Parker JA, Robitaille R, Wen XY, Barden C, Drapeau P.

Neurotherapeutics. 2019 Jul 24. doi: 10.1007/s13311-019-00765-w. [Epub ahead of print]


The Implementation Effectiveness of a Freely Available Pediatric Cancer Pain Assessment App: A Pilot Implementation Study.

Tutelman PR, Chambers CT, Stinson JN, Parker JA, Barwick M, Witteman HO, Jibb L, Stinson HC, Fernandez CV, Nathan PC, Campbell F, Irwin K.

JMIR Cancer. 2018 Dec 21;4(2):e10280. doi: 10.2196/10280.


Crossover from positive to negative optical torque in mesoscale optical matter.

Han F, Parker JA, Yifat Y, Peterson C, Gray SK, Scherer NF, Yan Z.

Nat Commun. 2018 Nov 20;9(1):4897. doi: 10.1038/s41467-018-07376-7.


Re: Metalens ophthalmic devices: the new world of optics is flat.

Parker JA.

Can J Ophthalmol. 2018 Oct;53(5):547. doi: 10.1016/j.jcjo.2018.05.003. Epub 2018 Jul 7. No abstract available.


Psychological interventions for needle-related procedural pain and distress in children and adolescents.

Birnie KA, Noel M, Chambers CT, Uman LS, Parker JA.

Cochrane Database Syst Rev. 2018 Oct 4;10:CD005179. doi: 10.1002/14651858.CD005179.pub4.


Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy.

Schmeisser K, Parker JA.

PLoS Genet. 2018 Sep 7;14(9):e1007561. doi: 10.1371/journal.pgen.1007561. eCollection 2018 Sep.


Gaussian thin system optics: revisited.

Parker JA.

Can J Ophthalmol. 2018 Aug;53(4):e129-e130. doi: 10.1016/j.jcjo.2018.01.010. Epub 2018 Mar 7. No abstract available.


Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo Using Caenorhabditis elegans.

Doyle JJ, Parker JA.

Methods Mol Biol. 2018;1806:179-191. doi: 10.1007/978-1-4939-8559-3_13.


K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D.

Parker JA, Volmar AY, Pavlopoulos S, Mattos C.

Structure. 2018 Jun 5;26(6):810-820.e4. doi: 10.1016/j.str.2018.03.018. Epub 2018 Apr 26.


Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.

Patten SA, Aggad D, Martinez J, Tremblay E, Petrillo J, Armstrong GA, La Fontaine A, Maios C, Liao M, Ciura S, Wen XY, Rafuse V, Ichida J, Zinman L, Julien JP, Kabashi E, Robitaille R, Korngut L, Parker JA, Drapeau P.

JCI Insight. 2017 Nov 16;2(22). pii: 97152. doi: 10.1172/jci.insight.97152. eCollection 2017 Nov 16.


Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.

Fardghassemi Y, Tauffenberger A, Gosselin S, Parker JA.

Dis Model Mech. 2017 Dec 19;10(12):1465-1480. doi: 10.1242/dmm.029736.


The K-Ras, N-Ras, and H-Ras Isoforms: Unique Conformational Preferences and Implications for Targeting Oncogenic Mutants.

Parker JA, Mattos C.

Cold Spring Harb Perspect Med. 2018 Aug 1;8(8). pii: a031427. doi: 10.1101/cshperspect.a031427. Review.


An engineered protein antagonist of K-Ras/B-Raf interaction.

Kauke MJ, Traxlmayr MW, Parker JA, Kiefer JD, Knihtila R, McGee J, Verdine G, Mattos C, Wittrup KD.

Sci Rep. 2017 Jul 19;7(1):5831. doi: 10.1038/s41598-017-05889-7.


Pain in Children With Cancer: Prevalence, Characteristics, and Parent Management.

Tutelman PR, Chambers CT, Stinson JN, Parker JA, Fernandez CV, Witteman HO, Nathan PC, Barwick M, Campbell F, Jibb LA, Irwin K.

Clin J Pain. 2018 Mar;34(3):198-206. doi: 10.1097/AJP.0000000000000531.


The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease.

Farina F, Lambert E, Commeau L, Lejeune FX, Roudier N, Fonte C, Parker JA, Boddaert J, Verny M, Baulieu EE, Neri C.

Sci Rep. 2017 Jun 21;7(1):4014. doi: 10.1038/s41598-017-04256-w.


The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects.

Johnson CW, Reid D, Parker JA, Salter S, Knihtila R, Kuzmic P, Mattos C.

J Biol Chem. 2017 Aug 4;292(31):12981-12993. doi: 10.1074/jbc.M117.778886. Epub 2017 Jun 19.


The Power of a Parent's Touch: Evaluation of Reach and Impact of a Targeted Evidence-Based YouTube Video.

Campbell-Yeo M, Dol J, Disher T, Benoit B, Chambers CT, Sheffield K, Boates T, Harrison D, Hewitt B, Jangaard K, Stinson J, Taddio A, Parker JA, Caddell K.

J Perinat Neonatal Nurs. 2017 Oct/Dec;31(4):341-349. doi: 10.1097/JPN.0000000000000263.


Expression of human Bcl-xL (Ser49) and (Ser62) mutants in Caenorhabditis elegans causes germline defects and aneuploidy.

Baruah PS, Beauchemin M, Parker JA, Bertrand R.

PLoS One. 2017 May 8;12(5):e0177413. doi: 10.1371/journal.pone.0177413. eCollection 2017.


Worms on the spectrum - C. elegans models in autism research.

Schmeisser K, Parker JA.

Exp Neurol. 2018 Jan;299(Pt A):199-206. doi: 10.1016/j.expneurol.2017.04.007. Epub 2017 Apr 20. Review.


A rapid chemical-genetic screen utilizing impaired movement phenotypes in C. elegans: Input into genetics of neurodevelopmental disorders.

Schmeisser K, Fardghassemi Y, Parker JA.

Exp Neurol. 2017 Jul;293:101-114. doi: 10.1016/j.expneurol.2017.03.022. Epub 2017 Apr 1.


C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress.

Melentijevic I, Toth ML, Arnold ML, Guasp RJ, Harinath G, Nguyen KC, Taub D, Parker JA, Neri C, Gabel CV, Hall DH, Driscoll M.

Nature. 2017 Feb 16;542(7641):367-371. doi: 10.1038/nature21362. Epub 2017 Feb 8.


ABNM: MOC Assessment.

Parker JA.

J Nucl Med. 2016 Oct;57(10):9N. No abstract available.


Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis.

Vayndorf EM, Scerbak C, Hunter S, Neuswanger JR, Toth M, Parker JA, Neri C, Driscoll M, Taylor BE.

NPJ Aging Mech Dis. 2016;2. pii: 16001. Epub 2016 Apr 7.


Mutations in CAPN1 Cause Autosomal-Recessive Hereditary Spastic Paraplegia.

Gan-Or Z, Bouslam N, Birouk N, Lissouba A, Chambers DB, Vérièpe J, Androschuk A, Laurent SB, Rochefort D, Spiegelman D, Dionne-Laporte A, Szuto A, Liao M, Figlewicz DA, Bouhouche A, Benomar A, Yahyaoui M, Ouazzani R, Yoon G, Dupré N, Suchowersky O, Bolduc FV, Parker JA, Dion PA, Drapeau P, Rouleau GA, Ouled Amar Bencheikh B.

Am J Hum Genet. 2016 Jun 2;98(6):1271. doi: 10.1016/j.ajhg.2016.05.009. Epub 2016 Jun 2. No abstract available.


Simple animal models for amyotrophic lateral sclerosis drug discovery.

Patten SA, Parker JA, Wen XY, Drapeau P.

Expert Opin Drug Discov. 2016 Aug;11(8):797-804. doi: 10.1080/17460441.2016.1196183. Epub 2016 Jun 13. Review.


Mutations in CAPN1 Cause Autosomal-Recessive Hereditary Spastic Paraplegia.

Gan-Or Z, Bouslam N, Birouk N, Lissouba A, Chambers DB, Vérièpe J, Androschuk A, Laurent SB, Rochefort D, Spiegelman D, Dionne-Laporte A, Szuto A, Liao M, Figlewicz DA, Bouhouche A, Benomar A, Yahyaoui M, Ouazzani R, Yoon G, Dupré N, Suchowersky O, Bolduc FV, Parker JA, Dion PA, Drapeau P, Rouleau GA, Ouled Amar Bencheikh B.

Am J Hum Genet. 2016 May 5;98(5):1038-1046. doi: 10.1016/j.ajhg.2016.04.002. Erratum in: Am J Hum Genet. 2016 Jun 2;98 (6):1271.


FET proteins regulate lifespan and neuronal integrity.

Therrien M, Rouleau GA, Dion PA, Parker JA.

Sci Rep. 2016 Apr 27;6:25159. doi: 10.1038/srep25159.


Maple Syrup Decreases TDP-43 Proteotoxicity in a Caenorhabditis elegans Model of Amyotrophic Lateral Sclerosis (ALS).

Aaron C, Beaudry G, Parker JA, Therrien M.

J Agric Food Chem. 2016 May 4;64(17):3338-44. doi: 10.1021/acs.jafc.5b05432. Epub 2016 Apr 20.


Value of ABNM Certification and MOC to Diplomates and the Public.

Parker JA.

J Nucl Med. 2016 Apr;57(4):10N, 13N. No abstract available.


Fragile lifespan expansion by dietary mitohormesis in C. elegans.

Tauffenberger A, Vaccaro A, Parker JA.

Aging (Albany NY). 2016 Jan;8(1):50-61.


Conserved pharmacological rescue of hereditary spastic paraplegia-related phenotypes across model organisms.

Julien C, Lissouba A, Madabattula S, Fardghassemi Y, Rosenfelt C, Androschuk A, Strautman J, Wong C, Bysice A, O'sullivan J, Rouleau GA, Drapeau P, Parker JA, Bolduc FV.

Hum Mol Genet. 2016 Mar 15;25(6):1088-99. doi: 10.1093/hmg/ddv632. Epub 2016 Jan 6.


A comprehensive categorical and bibliometric analysis of published research articles on pediatric pain from 1975 to 2010.

Caes L, Boerner KE, Chambers CT, Campbell-Yeo M, Stinson J, Birnie KA, Parker JA, Huguet A, Jordan A, MacLaren Chorney J, Schinkel M, Dol J.

Pain. 2016 Feb;157(2):302-13. doi: 10.1097/j.pain.0000000000000403. Review.


From the ABNM: Practice of Nuclear Medicine.

Parker JA.

J Nucl Med. 2015 Nov;56(11):18N. No abstract available.


Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons.

Vérièpe J, Fossouo L, Parker JA.

Nat Commun. 2015 Jun 10;6:7319. doi: 10.1038/ncomms8319.


G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA.

Aulas A, Caron G, Gkogkas CG, Mohamed NV, Destroismaisons L, Sonenberg N, Leclerc N, Parker JA, Vande Velde C.

J Cell Biol. 2015 Apr 13;209(1):73-84. doi: 10.1083/jcb.201408092. Epub 2015 Apr 6.


Insufficient glucocorticoid signaling and elevated inflammation in coronary heart disease patients with comorbid depression.

Nikkheslat N, Zunszain PA, Horowitz MA, Barbosa IG, Parker JA, Myint AM, Schwarz MJ, Tylee AT, Carvalho LA, Pariante CM.

Brain Behav Immun. 2015 Aug;48:8-18. doi: 10.1016/j.bbi.2015.02.002. Epub 2015 Feb 12.


Yttrium-90 ibritumomab tiuxetan followed by rituximab maintenance as treatment for patients with diffuse large B-cell lymphoma are not candidates for autologous stem cell transplant.

Arnason JE, Luptakova K, Rosenblatt J, Tzachanis D, Avigan D, Zwicker JI, Levine J, Kim M, Parker JA, Grant B, Joyce RM.

Acta Haematol. 2015;133(4):347-53. doi: 10.1159/000368291. Epub 2015 Feb 7.


Acceptability by parents and children of deception in pediatric research.

Noel M, Boerner KE, Birnie KA, Caes L, Parker JA, Chambers CT, Fernandez CV, Lee K.

J Dev Behav Pediatr. 2015 Feb-Mar;36(2):75-85. doi: 10.1097/DBP.0000000000000122.


ABNM international In-Training Examination program.

Parker JA.

J Nucl Med. 2015 Feb;56(2):10N. No abstract available.


The Ras-Membrane Interface: Isoform-specific Differences in The Catalytic Domain.

Parker JA, Mattos C.

Mol Cancer Res. 2015 Apr;13(4):595-603. doi: 10.1158/1541-7786.MCR-14-0535. Epub 2015 Jan 7. Review.


Anaesthetic management of a parturient with uncorrected tetralogy of Fallot undergoing caesarean section.

Parker JA, Grange C.

Int J Obstet Anesth. 2015 Feb;24(1):88-90. doi: 10.1016/j.ijoa.2014.10.002. Epub 2014 Oct 20. No abstract available.


Hepatitis A outbreak associated with kava drinking.

Parker JA, Kurien TT, Huppatz C.

Commun Dis Intell Q Rep. 2014 Mar 31;38(1):E26-8.


Relevance of Water Temperature, Apparatus, and Age to Children's Pain during the Cold Pressor Task.

Birnie KA, Parker JA, Chambers CT.

Pain Pract. 2016 Jan;16(1):46-56. doi: 10.1111/papr.12257. Epub 2014 Nov 11.


ACR Appropriateness Criteria® rib fractures.

Expert Panel on Thoracic Imaging, Henry TS, Kirsch J, Kanne JP, Chung JH, Donnelly EF, Ginsburg ME, Heitkamp DE, Kazerooni EA, Ketai LH, McComb BL, Parker JA, Ravenel JG, Restrepo CS, Saleh AG, Shah RD, Steiner RM, Suh RD, Mohammed TL; American College of Radiology.

J Thorac Imaging. 2014 Nov;29(6):364-6. doi: 10.1097/RTI.0000000000000113.


Deciphering genetic interactions between ALS genes using C. elegans.

Therrien M, Parker JA.

Worm. 2014 May 8;3:e29047. doi: 10.4161/worm.29047. eCollection 2014.


Tau hyperphosphorylation and deregulation of calcineurin in mouse models of Huntington's disease.

Gratuze M, Noël A, Julien C, Cisbani G, Milot-Rousseau P, Morin F, Dickler M, Goupil C, Bezeau F, Poitras I, Bissonnette S, Whittington RA, Hébert SS, Cicchetti F, Parker JA, Samadi P, Planel E.

Hum Mol Genet. 2015 Jan 1;24(1):86-99. doi: 10.1093/hmg/ddu456. Epub 2014 Sep 8.


TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons.

Aggad D, Vérièpe J, Tauffenberger A, Parker JA.

J Neurosci. 2014 Sep 3;34(36):12093-103. doi: 10.1523/JNEUROSCI.2495-13.2014.


Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons.

Scerbak C, Vayndorf EM, Parker JA, Neri C, Driscoll M, Taylor BE.

Front Genet. 2014 Jul 23;5:212. doi: 10.3389/fgene.2014.00212. eCollection 2014.

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