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Items: 1 to 50 of 77

1.

Genetic selection of athletic success in sport-hunting dogs.

Kim J, Williams FJ, Dreger DL, Plassais J, Davis BW, Parker HG, Ostrander EA.

Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7212-E7221. doi: 10.1073/pnas.1800455115. Epub 2018 Jul 3.

2.

Studies of modern Italian dog populations reveal multiple patterns for domestic breed evolution.

Talenti A, Dreger DL, Frattini S, Polli M, Marelli S, Harris AC, Liotta L, Cocco R, Hogan AN, Bigi D, Caniglia R, Parker HG, Pagnacco G, Ostrander EA, Crepaldi P.

Ecol Evol. 2018 Feb 14;8(5):2911-2925. doi: 10.1002/ece3.3842. eCollection 2018 Mar.

3.

Genomic Analyses Reveal the Influence of Geographic Origin, Migration, and Hybridization on Modern Dog Breed Development.

Parker HG, Dreger DL, Rimbault M, Davis BW, Mullen AB, Carpintero-Ramirez G, Ostrander EA.

Cell Rep. 2017 Apr 25;19(4):697-708. doi: 10.1016/j.celrep.2017.03.079.

4.

The bald and the beautiful: hairlessness in domestic dog breeds.

Parker HG, Harris A, Dreger DL, Davis BW, Ostrander EA.

Philos Trans R Soc Lond B Biol Sci. 2017 Feb 5;372(1713). pii: 20150488.

5.

Whole-genome sequence, SNP chips and pedigree structure: building demographic profiles in domestic dog breeds to optimize genetic-trait mapping.

Dreger DL, Rimbault M, Davis BW, Bhatnagar A, Parker HG, Ostrander EA.

Dis Model Mech. 2016 Dec 1;9(12):1445-1460. Epub 2016 Nov 17.

6.

Commonalities in Development of Pure Breeds and Population Isolates Revealed in the Genome of the Sardinian Fonni's Dog.

Dreger DL, Davis BW, Cocco R, Sechi S, Di Cerbo A, Parker HG, Polli M, Marelli SP, Crepaldi P, Ostrander EA.

Genetics. 2016 Oct;204(2):737-755. Epub 2016 Aug 12.

7.

Demographically-Based Evaluation of Genomic Regions under Selection in Domestic Dogs.

Freedman AH, Schweizer RM, Ortega-Del Vecchyo D, Han E, Davis BW, Gronau I, Silva PM, Galaverni M, Fan Z, Marx P, Lorente-Galdos B, Ramirez O, Hormozdiari F, Alkan C, Vilà C, Squire K, Geffen E, Kusak J, Boyko AR, Parker HG, Lee C, Tadigotla V, Siepel A, Bustamante CD, Harkins TT, Nelson SF, Marques-Bonet T, Ostrander EA, Wayne RK, Novembre J.

PLoS Genet. 2016 Mar 4;12(3):e1005851. doi: 10.1371/journal.pgen.1005851. eCollection 2016 Mar.

8.

Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor.

Decker B, Davis BW, Rimbault M, Long AH, Karlins E, Jagannathan V, Reiman R, Parker HG, Drögemüller C, Corneveaux JJ, Chapman ES, Trent JM, Leeb T, Huentelman MJ, Wayne RK, Karyadi DM, Ostrander EA.

Genome Res. 2015 Nov;25(11):1646-55. doi: 10.1101/gr.190314.115. Epub 2015 Jul 31.

9.

Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test.

Decker B, Parker HG, Dhawan D, Kwon EM, Karlins E, Davis BW, Ramos-Vara JA, Bonney PL, McNiel EA, Knapp DW, Ostrander EA.

Mol Cancer Res. 2015 Jun;13(6):993-1002. doi: 10.1158/1541-7786.MCR-14-0689. Epub 2015 Mar 12.

10.

From caveman companion to medical innovator: genomic insights into the origin and evolution of domestic dogs.

Parker HG, Gilbert SF.

Adv Genomics Genet. 2015;5:239-255. doi: 10.2147/AGG.S57678. Epub 2015 Jun 12.

11.

Cancer. Hiding in plain view--an ancient dog in the modern world.

Parker HG, Ostrander EA.

Science. 2014 Jan 24;343(6169):376-8. doi: 10.1126/science.1248812. No abstract available. Erratum in: Science. 2014 Feb 14;343(6172):730.

12.

Genome sequencing highlights the dynamic early history of dogs.

Freedman AH, Gronau I, Schweizer RM, Ortega-Del Vecchyo D, Han E, Silva PM, Galaverni M, Fan Z, Marx P, Lorente-Galdos B, Beale H, Ramirez O, Hormozdiari F, Alkan C, Vilà C, Squire K, Geffen E, Kusak J, Boyko AR, Parker HG, Lee C, Tadigotla V, Wilton A, Siepel A, Bustamante CD, Harkins TT, Nelson SF, Ostrander EA, Marques-Bonet T, Wayne RK, Novembre J.

PLoS Genet. 2014 Jan;10(1):e1004016. doi: 10.1371/journal.pgen.1004016. Epub 2014 Jan 16. Erratum in: PLoS Genet. 2014 Aug;10(8):e1004631. Wilton, Alan [added].

13.

A copy number variant at the KITLG locus likely confers risk for canine squamous cell carcinoma of the digit.

Karyadi DM, Karlins E, Decker B, vonHoldt BM, Carpintero-Ramirez G, Parker HG, Wayne RK, Ostrander EA.

PLoS Genet. 2013 Mar;9(3):e1003409. doi: 10.1371/journal.pgen.1003409. Epub 2013 Mar 28.

14.

Identification of a mutation that is associated with the saddle tan and black-and-tan phenotypes in Basset Hounds and Pembroke Welsh Corgis.

Dreger DL, Parker HG, Ostrander EA, Schmutz SM.

J Hered. 2013 May-Jun;104(3):399-406. doi: 10.1093/jhered/est012. Epub 2013 Mar 21.

PMID:
23519866
15.

Telomere length correlates with life span of dog breeds.

Fick LJ, Fick GH, Li Z, Cao E, Bao B, Heffelfinger D, Parker HG, Ostrander EA, Riabowol K.

Cell Rep. 2012 Dec 27;2(6):1530-6. doi: 10.1016/j.celrep.2012.11.021.

16.

Identification of recent hybridization between gray wolves and domesticated dogs by SNP genotyping.

vonHoldt BM, Pollinger JP, Earl DA, Parker HG, Ostrander EA, Wayne RK.

Mamm Genome. 2013 Feb;24(1-2):80-8. doi: 10.1007/s00335-012-9432-0. Epub 2012 Oct 12.

PMID:
23064780
17.

The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer.

Shearin AL, Hedan B, Cadieu E, Erich SA, Schmidt EV, Faden DL, Cullen J, Abadie J, Kwon EM, Gröne A, Devauchelle P, Rimbault M, Karyadi DM, Lynch M, Galibert F, Breen M, Rutteman GR, André C, Parker HG, Ostrander EA.

Cancer Epidemiol Biomarkers Prev. 2012 Jul;21(7):1019-27. doi: 10.1158/1055-9965.EPI-12-0190-T. Epub 2012 May 23.

18.

Myxomatous mitral valve disease in dogs: does size matter?

Parker HG, Kilroy-Glynn P.

J Vet Cardiol. 2012 Mar;14(1):19-29. doi: 10.1016/j.jvc.2012.01.006. Epub 2012 Feb 20. Review.

19.

Genomic analyses of modern dog breeds.

Parker HG.

Mamm Genome. 2012 Feb;23(1-2):19-27. doi: 10.1007/s00335-011-9387-6. Epub 2012 Jan 10.

20.

Breed-specific ancestry studies and genome-wide association analysis highlight an association between the MYH9 gene and heat tolerance in Alaskan sprint racing sled dogs.

Huson HJ, vonHoldt BM, Rimbault M, Byers AM, Runstadler JA, Parker HG, Ostrander EA.

Mamm Genome. 2012 Feb;23(1-2):178-94. doi: 10.1007/s00335-011-9374-y. Epub 2011 Nov 22.

21.

Subcutaneous 5-azacitidine treatment of naturally occurring canine urothelial carcinoma: a novel epigenetic approach to human urothelial carcinoma drug development.

Hahn NM, Bonney PL, Dhawan D, Jones DR, Balch C, Guo Z, Hartman-Frey C, Fang F, Parker HG, Kwon EM, Ostrander EA, Nephew KP, Knapp DW.

J Urol. 2012 Jan;187(1):302-9. doi: 10.1016/j.juro.2011.09.010. Epub 2011 Nov 17.

22.

Man's best friend becomes biology's best in show: genome analyses in the domestic dog.

Parker HG, Shearin AL, Ostrander EA.

Annu Rev Genet. 2010;44:309-36. doi: 10.1146/annurev-genet-102808-115200. Review.

23.

A simple genetic architecture underlies morphological variation in dogs.

Boyko AR, Quignon P, Li L, Schoenebeck JJ, Degenhardt JD, Lohmueller KE, Zhao K, Brisbin A, Parker HG, vonHoldt BM, Cargill M, Auton A, Reynolds A, Elkahloun AG, Castelhano M, Mosher DS, Sutter NB, Johnson GS, Novembre J, Hubisz MJ, Siepel A, Wayne RK, Bustamante CD, Ostrander EA.

PLoS Biol. 2010 Aug 10;8(8):e1000451. doi: 10.1371/journal.pbio.1000451.

24.

A genetic dissection of breed composition and performance enhancement in the Alaskan sled dog.

Huson HJ, Parker HG, Runstadler J, Ostrander EA.

BMC Genet. 2010 Jul 22;11:71. doi: 10.1186/1471-2156-11-71.

25.

An insertion in the RSPO2 gene correlates with improper coat in the Portuguese water dog.

Parker HG, Chase K, Cadieu E, Lark KG, Ostrander EA.

J Hered. 2010 Sep-Oct;101(5):612-7. doi: 10.1093/jhered/esq068. Epub 2010 Jun 18.

26.

Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication.

Vonholdt BM, Pollinger JP, Lohmueller KE, Han E, Parker HG, Quignon P, Degenhardt JD, Boyko AR, Earl DA, Auton A, Reynolds A, Bryc K, Brisbin A, Knowles JC, Mosher DS, Spady TC, Elkahloun A, Geffen E, Pilot M, Jedrzejewski W, Greco C, Randi E, Bannasch D, Wilton A, Shearman J, Musiani M, Cargill M, Jones PG, Qian Z, Huang W, Ding ZL, Zhang YP, Bustamante CD, Ostrander EA, Novembre J, Wayne RK.

Nature. 2010 Apr 8;464(7290):898-902. doi: 10.1038/nature08837. Epub 2010 Mar 17.

27.

Fine mapping a locus controlling leg morphology in the domestic dog.

Quignon P, Schoenebeck JJ, Chase K, Parker HG, Mosher DS, Johnson GS, Lark KG, Ostrander EA.

Cold Spring Harb Symp Quant Biol. 2009;74:327-33. doi: 10.1101/sqb.2009.74.009. Epub 2009 Aug 28.

28.

Coat variation in the domestic dog is governed by variants in three genes.

Cadieu E, Neff MW, Quignon P, Walsh K, Chase K, Parker HG, Vonholdt BM, Rhue A, Boyko A, Byers A, Wong A, Mosher DS, Elkahloun AG, Spady TC, André C, Lark KG, Cargill M, Bustamante CD, Wayne RK, Ostrander EA.

Science. 2009 Oct 2;326(5949):150-3. doi: 10.1126/science.1177808. Epub 2009 Aug 27.

29.

Complex population structure in African village dogs and its implications for inferring dog domestication history.

Boyko AR, Boyko RH, Boyko CM, Parker HG, Castelhano M, Corey L, Degenhardt JD, Auton A, Hedimbi M, Kityo R, Ostrander EA, Schoenebeck J, Todhunter RJ, Jones P, Bustamante CD.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13903-8. doi: 10.1073/pnas.0902129106. Epub 2009 Aug 3.

30.

An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs.

Parker HG, VonHoldt BM, Quignon P, Margulies EH, Shao S, Mosher DS, Spady TC, Elkahloun A, Cargill M, Jones PG, Maslen CL, Acland GM, Sutter NB, Kuroki K, Bustamante CD, Wayne RK, Ostrander EA.

Science. 2009 Aug 21;325(5943):995-8. doi: 10.1126/science.1173275. Epub 2009 Jul 16.

31.

Epidemiology, pathology, and genetics of histiocytic sarcoma in the Bernese mountain dog breed.

Abadie J, Hédan B, Cadieu E, De Brito C, Devauchelle P, Bourgain C, Parker HG, Vaysse A, Margaritte-Jeannin P, Galibert F, Ostrander EA, André C.

J Hered. 2009 Jul-Aug;100 Suppl 1:S19-27. doi: 10.1093/jhered/esp039. Epub 2009 Jun 16.

32.

Population genomics of the inbred Scandinavian wolf.

Hagenblad J, Olsson M, Parker HG, Ostrander EA, Ellegren H.

Mol Ecol. 2009 Apr;18(7):1341-51. doi: 10.1111/j.1365-294X.2009.04120.x.

33.

A neonatal encephalopathy with seizures in standard poodle dogs with a missense mutation in the canine ortholog of ATF2.

Chen X, Johnson GS, Schnabel RD, Taylor JF, Johnson GC, Parker HG, Patterson EE, Katz ML, Awano T, Khan S, O'Brien DP.

Neurogenetics. 2008 Feb;9(1):41-9. Epub 2007 Dec 12.

PMID:
18074159
34.

Breed relationships facilitate fine-mapping studies: a 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds.

Parker HG, Kukekova AV, Akey DT, Goldstein O, Kirkness EF, Baysac KC, Mosher DS, Aguirre GD, Acland GM, Ostrander EA.

Genome Res. 2007 Nov;17(11):1562-71. Epub 2007 Oct 4.

35.

A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs.

Mosher DS, Quignon P, Bustamante CD, Sutter NB, Mellersh CS, Parker HG, Ostrander EA.

PLoS Genet. 2007 May 25;3(5):e79. Epub 2007 Apr 30.

36.

A single IGF1 allele is a major determinant of small size in dogs.

Sutter NB, Bustamante CD, Chase K, Gray MM, Zhao K, Zhu L, Padhukasahasram B, Karlins E, Davis S, Jones PG, Quignon P, Johnson GS, Parker HG, Fretwell N, Mosher DS, Lawler DF, Satyaraj E, Nordborg M, Lark KG, Wayne RK, Ostrander EA.

Science. 2007 Apr 6;316(5821):112-5. Erratum in: Science. 2007 Jun 1;316(5829):1284.

37.

Finding cardiovascular disease genes in the dog.

Parker HG, Meurs KM, Ostrander EA.

J Vet Cardiol. 2006 Nov;8(2):115-27. doi: 10.1016/j.jvc.2006.04.002. Epub 2006 Oct 10.

38.

Molecular genetics: DNA analysis of a putative dog clone.

Parker HG, Kruglyak L, Ostrander EA.

Nature. 2006 Mar 9;440(7081):E1-2.

39.

Genome sequence, comparative analysis and haplotype structure of the domestic dog.

Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ 3rd, Zody MC, Mauceli E, Xie X, Breen M, Wayne RK, Ostrander EA, Ponting CP, Galibert F, Smith DR, DeJong PJ, Kirkness E, Alvarez P, Biagi T, Brockman W, Butler J, Chin CW, Cook A, Cuff J, Daly MJ, DeCaprio D, Gnerre S, Grabherr M, Kellis M, Kleber M, Bardeleben C, Goodstadt L, Heger A, Hitte C, Kim L, Koepfli KP, Parker HG, Pollinger JP, Searle SM, Sutter NB, Thomas R, Webber C, Baldwin J, Abebe A, Abouelleil A, Aftuck L, Ait-Zahra M, Aldredge T, Allen N, An P, Anderson S, Antoine C, Arachchi H, Aslam A, Ayotte L, Bachantsang P, Barry A, Bayul T, Benamara M, Berlin A, Bessette D, Blitshteyn B, Bloom T, Blye J, Boguslavskiy L, Bonnet C, Boukhgalter B, Brown A, Cahill P, Calixte N, Camarata J, Cheshatsang Y, Chu J, Citroen M, Collymore A, Cooke P, Dawoe T, Daza R, Decktor K, DeGray S, Dhargay N, Dooley K, Dooley K, Dorje P, Dorjee K, Dorris L, Duffey N, Dupes A, Egbiremolen O, Elong R, Falk J, Farina A, Faro S, Ferguson D, Ferreira P, Fisher S, FitzGerald M, Foley K, Foley C, Franke A, Friedrich D, Gage D, Garber M, Gearin G, Giannoukos G, Goode T, Goyette A, Graham J, Grandbois E, Gyaltsen K, Hafez N, Hagopian D, Hagos B, Hall J, Healy C, Hegarty R, Honan T, Horn A, Houde N, Hughes L, Hunnicutt L, Husby M, Jester B, Jones C, Kamat A, Kanga B, Kells C, Khazanovich D, Kieu AC, Kisner P, Kumar M, Lance K, Landers T, Lara M, Lee W, Leger JP, Lennon N, Leuper L, LeVine S, Liu J, Liu X, Lokyitsang Y, Lokyitsang T, Lui A, Macdonald J, Major J, Marabella R, Maru K, Matthews C, McDonough S, Mehta T, Meldrim J, Melnikov A, Meneus L, Mihalev A, Mihova T, Miller K, Mittelman R, Mlenga V, Mulrain L, Munson G, Navidi A, Naylor J, Nguyen T, Nguyen N, Nguyen C, Nguyen T, Nicol R, Norbu N, Norbu C, Novod N, Nyima T, Olandt P, O'Neill B, O'Neill K, Osman S, Oyono L, Patti C, Perrin D, Phunkhang P, Pierre F, Priest M, Rachupka A, Raghuraman S, Rameau R, Ray V, Raymond C, Rege F, Rise C, Rogers J, Rogov P, Sahalie J, Settipalli S, Sharpe T, Shea T, Sheehan M, Sherpa N, Shi J, Shih D, Sloan J, Smith C, Sparrow T, Stalker J, Stange-Thomann N, Stavropoulos S, Stone C, Stone S, Sykes S, Tchuinga P, Tenzing P, Tesfaye S, Thoulutsang D, Thoulutsang Y, Topham K, Topping I, Tsamla T, Vassiliev H, Venkataraman V, Vo A, Wangchuk T, Wangdi T, Weiand M, Wilkinson J, Wilson A, Yadav S, Yang S, Yang X, Young G, Yu Q, Zainoun J, Zembek L, Zimmer A, Lander ES.

Nature. 2005 Dec 8;438(7069):803-19.

PMID:
16341006
40.

Canine genomics and genetics: running with the pack.

Parker HG, Ostrander EA.

PLoS Genet. 2005 Nov;1(5):e58. Review.

41.

Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps.

Murphy WJ, Larkin DM, Everts-van der Wind A, Bourque G, Tesler G, Auvil L, Beever JE, Chowdhary BP, Galibert F, Gatzke L, Hitte C, Meyers SN, Milan D, Ostrander EA, Pape G, Parker HG, Raudsepp T, Rogatcheva MB, Schook LB, Skow LC, Welge M, Womack JE, O'brien SJ, Pevzner PA, Lewin HA.

Science. 2005 Jul 22;309(5734):613-7.

42.

Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk.

Modiano JF, Breen M, Burnett RC, Parker HG, Inusah S, Thomas R, Avery PR, Lindblad-Toh K, Ostrander EA, Cutter GC, Avery AC.

Cancer Res. 2005 Jul 1;65(13):5654-61.

43.

SNPs in ecological and conservation studies: a test in the Scandinavian wolf population.

Seddon JM, Parker HG, Ostrander EA, Ellegren H.

Mol Ecol. 2005 Feb;14(2):503-11.

PMID:
15660941
44.

Extensive and breed-specific linkage disequilibrium in Canis familiaris.

Sutter NB, Eberle MA, Parker HG, Pullar BJ, Kirkness EF, Kruglyak L, Ostrander EA.

Genome Res. 2004 Dec;14(12):2388-96. Epub 2004 Nov 15.

45.

An integrated 4249 marker FISH/RH map of the canine genome.

Breen M, Hitte C, Lorentzen TD, Thomas R, Cadieu E, Sabacan L, Scott A, Evanno G, Parker HG, Kirkness EF, Hudson R, Guyon R, Mahairas GG, Gelfenbeyn B, Fraser CM, André C, Galibert F, Ostrander EA.

BMC Genomics. 2004 Sep 13;5:65.

46.

Genetic structure of the purebred domestic dog.

Parker HG, Kim LV, Sutter NB, Carlson S, Lorentzen TD, Malek TB, Johnson GS, DeFrance HB, Ostrander EA, Kruglyak L.

Science. 2004 May 21;304(5674):1160-4.

47.

Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the Randomized Evaluation of PCI Linking Angiomax to Reduced Clinical Events [REPLACE]-1 trial).

Lincoff AM, Bittl JA, Kleiman NS, Sarembock IJ, Jackman JD, Mehta S, Tannenbaum MA, Niederman AL, Bachinsky WB, Tift-Mann J 3rd, Parker HG, Kereiakes DJ, Harrington RA, Feit F, Maierson ES, Chew DP, Topol EJ; REPLACE-1 Investigators.

Am J Cardiol. 2004 May 1;93(9):1092-6.

PMID:
15110198
48.

A 1-Mb resolution radiation hybrid map of the canine genome.

Guyon R, Lorentzen TD, Hitte C, Kim L, Cadieu E, Parker HG, Quignon P, Lowe JK, Renier C, Gelfenbeyn B, Vignaux F, DeFrance HB, Gloux S, Mahairas GG, André C, Galibert F, Ostrander EA.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5296-301. Epub 2003 Apr 16.

49.

Comparison of MultiMap and TSP/CONCORDE for constructing radiation hybrid maps.

Hitte C, Lorentzen TD, Guyon R, Kim L, Cadieu E, Parker HG, Quignon P, Lowe JK, Gelfenbeyn B, Andre C, Ostrander EA, Galibert F.

J Hered. 2003 Jan-Feb;94(1):9-13.

PMID:
12692156
50.

Meiotic linkage mapping of 52 genes onto the canine map does not identify significant levels of microrearrangement.

Parker HG, Yuhua X, Mellersh CS, Khan S, Shibuya H, Johnson GS, Ostrander EA.

Mamm Genome. 2001 Sep;12(9):713-8.

PMID:
11641719

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