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Items: 24

1.

"Cancer 2015": A Prospective, Population-Based Cancer Cohort-Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic.

Parisot JP, Thorne H, Fellowes A, Doig K, Lucas M, McNeil JJ, Doble B, Dobrovic A, John T, James PA, Lipton L, Ashley D, Hayes T, McMurrick P, Richardson G, Lorgelly P, Fox SB, Thomas DM.

J Pers Med. 2015 Oct 29;5(4):354-69. doi: 10.3390/jpm5040354.

2.

Cancer 2015: a longitudinal whole-of-system study of genomic cancer medicine.

Thomas DM, Fox S, Lorgelly PK, Ashley D, Richardson G, Lipton L, Parisot JP, Lucas M, McNeil J, Wright M; Cancer 2015 Investigators.

Drug Discov Today. 2015 Dec;20(12):1429-32. doi: 10.1016/j.drudis.2015.10.009. Epub 2015 Oct 19.

PMID:
26494144
3.

HIV-1 and Human PEG10 Frameshift Elements Are Functionally Distinct and Distinguished by Novel Small Molecule Modulators.

Cardno TS, Shimaki Y, Sleebs BE, Lackovic K, Parisot JP, Moss RM, Crowe-McAuliffe C, Mathew SF, Edgar CD, Kleffmann T, Tate WP.

PLoS One. 2015 Oct 8;10(10):e0139036. doi: 10.1371/journal.pone.0139036. eCollection 2015.

4.

Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.

Wong SQ, Fellowes A, Doig K, Ellul J, Bosma TJ, Irwin D, Vedururu R, Tan AY, Weiss J, Chan KS, Lucas M, Thomas DM, Dobrovic A, Parisot JP, Fox SB.

Br J Cancer. 2015 Apr 14;112(8):1411-20. doi: 10.1038/bjc.2015.80. Epub 2015 Mar 5.

5.

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing.

Wong SQ, Li J, Tan AY, Vedururu R, Pang JM, Do H, Ellul J, Doig K, Bell A, MacArthur GA, Fox SB, Thomas DM, Fellowes A, Parisot JP, Dobrovic A; CANCER 2015 Cohort.

BMC Med Genomics. 2014 May 13;7:23. doi: 10.1186/1755-8794-7-23.

6.

De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterization.

Brady RM, Vom A, Roy MJ, Toovey N, Smith BJ, Moss RM, Hatzis E, Huang DC, Parisot JP, Yang H, Street IP, Colman PM, Czabotar PE, Baell JB, Lessene G.

J Med Chem. 2014 Feb 27;57(4):1323-43. doi: 10.1021/jm401948b. Epub 2014 Feb 5.

PMID:
24456288
7.

Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL.

Sleebs BE, Kersten WJ, Kulasegaram S, Nikolakopoulos G, Hatzis E, Moss RM, Parisot JP, Yang H, Czabotar PE, Fairlie WD, Lee EF, Adams JM, Chen L, van Delft MF, Lowes KN, Wei A, Huang DC, Colman PM, Street IP, Baell JB, Watson K, Lessene G.

J Med Chem. 2013 Jul 11;56(13):5514-40. doi: 10.1021/jm400556w. Epub 2013 Jun 26.

PMID:
23767404
8.

Structure-guided design of a selective BCL-X(L) inhibitor.

Lessene G, Czabotar PE, Sleebs BE, Zobel K, Lowes KN, Adams JM, Baell JB, Colman PM, Deshayes K, Fairbrother WJ, Flygare JA, Gibbons P, Kersten WJ, Kulasegaram S, Moss RM, Parisot JP, Smith BJ, Street IP, Yang H, Huang DC, Watson KG.

Nat Chem Biol. 2013 Jun;9(6):390-7. doi: 10.1038/nchembio.1246. Epub 2013 Apr 21.

PMID:
23603658
9.

An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.

Willoughby LF, Schlosser T, Manning SA, Parisot JP, Street IP, Richardson HE, Humbert PO, Brumby AM.

Dis Model Mech. 2013 Mar;6(2):521-9. doi: 10.1242/dmm.009985. Epub 2012 Sep 20.

10.

An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets.

Falk H, Connor T, Yang H, Loft KJ, Alcindor JL, Nikolakopoulos G, Surjadi RN, Bentley JD, Hattarki MK, Dolezal O, Murphy JM, Monahan BJ, Peat TS, Thomas T, Baell JB, Parisot JP, Street IP.

J Biomol Screen. 2011 Dec;16(10):1196-205. doi: 10.1177/1087057111421631. Epub 2011 Nov 14.

PMID:
22086725
11.

Field chronobiology of a molluscan bivalve: how the moon and sun cycles interact to drive oyster activity rhythms.

Tran D, Nadau A, Durrieu G, Ciret P, Parisot JP, Massabuau JC.

Chronobiol Int. 2011 May;28(4):307-17. doi: 10.3109/07420528.2011.565897.

PMID:
21539422
12.

Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity.

Sleebs BE, Czabotar PE, Fairbrother WJ, Fairlie WD, Flygare JA, Huang DC, Kersten WJ, Koehler MF, Lessene G, Lowes K, Parisot JP, Smith BJ, Smith ML, Souers AJ, Street IP, Yang H, Baell JB.

J Med Chem. 2011 Mar 24;54(6):1914-26. doi: 10.1021/jm101596e. Epub 2011 Mar 2.

PMID:
21366295
13.

Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi.

Holloway GA, Parisot JP, Novello PM, Watson KG, Armstrong T, Thompson RC, Street IP, Baell JB.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1816-8. doi: 10.1016/j.bmcl.2010.02.022. Epub 2010 Feb 8.

PMID:
20185305
14.

Inhibitors of Leishmania GDP-mannose pyrophosphorylase identified by high-throughput screening of small-molecule chemical library.

Lackovic K, Parisot JP, Sleebs N, Baell JB, Debien L, Watson KG, Curtis JM, Handman E, Street IP, Kedzierski L.

Antimicrob Agents Chemother. 2010 May;54(5):1712-9. doi: 10.1128/AAC.01634-09. Epub 2010 Feb 16.

15.

Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity.

Holloway GA, Charman WN, Fairlamb AH, Brun R, Kaiser M, Kostewicz E, Novello PM, Parisot JP, Richardson J, Street IP, Watson KG, Baell JB.

Antimicrob Agents Chemother. 2009 Jul;53(7):2824-33. doi: 10.1128/AAC.01568-08. Epub 2009 Apr 13.

16.

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening.

Holloway GA, Baell JB, Fairlamb AH, Novello PM, Parisot JP, Richardson J, Watson KG, Street IP.

Bioorg Med Chem Lett. 2007 Mar 1;17(5):1422-7. Epub 2006 Dec 3.

17.

Induction of insulin-like growth factor binding protein expression by ICI 182,780 in a tamoxifen-resistant human breast cancer cell line.

Parisot JP, Leeding KS, Hu XF, DeLuise M, Zalcberg JR, Bach LA.

Breast Cancer Res Treat. 1999 Jun;55(3):231-42.

PMID:
10517168
18.

Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line.

Parisot JP, Hu XF, DeLuise M, Zalcberg JR.

Br J Cancer. 1999 Feb;79(5-6):693-700.

19.

The pure antiestrogen ICI 182,780 binds to a high-affinity site distinct from the estrogen receptor.

Parisot JP, Hu XF, Sutherland RL, Wakeling A, Zalcberg JR, DeLuise M.

Int J Cancer. 1995 Aug 9;62(4):480-4.

PMID:
7635575
20.

A study of chemical systems using signal flow graph theory.

Dobrijevic M, Parisot JP, Dutour I.

Adv Space Res. 1995;16(2):105-8.

PMID:
11543528
21.
22.

Photochemical modeling of Titan's atmosphere

Toublanc D, Parisot JP, Brillet J, Gautier D, Raulin F, McKay CP.

Icarus. 1995 Jan;113(1):2-26. Erratum in: Icarus 1995 Sep;117(1):218.

PMID:
11538950
23.

A study of chemical systems using signal flow graph theory: application to Neptune.

Dobrijevic M, Parisot JP, Dutour I.

Planet Space Sci. 1995 Jan-Feb;43(1-2):15-24.

PMID:
11538428
24.

[Gardner's syndrome. A further case].

Sallet J, Helenon C, Becart C, Parisot JP.

J Chir (Paris). 1969 Oct;98(4):309-22. French. No abstract available.

PMID:
5366998

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