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Items: 48

1.

In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos.

Aspatwar A, Hammaren M, Parikka M, Parkkila S, Carta F, Bozdag M, Vullo D, Supuran CT.

J Enzyme Inhib Med Chem. 2020 Dec;35(1):65-71. doi: 10.1080/14756366.2019.1683007.

2.

Mycobacterium tuberculosis β-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs.

Aspatwar A, Kairys V, Rala S, Parikka M, Bozdag M, Carta F, Supuran CT, Parkkila S.

Int J Mol Sci. 2019 Oct 17;20(20). pii: E5153. doi: 10.3390/ijms20205153. Review.

3.

Characterization of immune response against Mycobacterium marinum infection in the main hematopoietic organ of adult zebrafish (Danio rerio).

Harjula SE, Saralahti AK, Ojanen MJT, Rantapero T, Uusi-Mäkelä MIE, Nykter M, Lohi O, Parikka M, Rämet M.

Dev Comp Immunol. 2020 Feb;103:103523. doi: 10.1016/j.dci.2019.103523. Epub 2019 Oct 15.

4.

Rapid Evaluation of Toxicity of Chemical Compounds Using Zebrafish Embryos.

Aspatwar A, Hammaren MM, Parikka M, Parkkila S.

J Vis Exp. 2019 Aug 25;(150). doi: 10.3791/59315.

PMID:
31498322
5.

PCR-based zebrafish model for personalised medicine in head and neck cancer.

Al-Samadi A, Tuomainen K, Kivimäki A, Salem A, Al-Kubati S, Hyytiäinen A, Parikka M, Mesimäki K, Wilkman T, Mäkitie A, Grenman R, Salo T.

J Transl Med. 2019 Jul 22;17(1):235. doi: 10.1186/s12967-019-1985-1.

6.

Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on In Vitro and In Vivo Studies.

Aspatwar A, Winum JY, Carta F, Supuran CT, Hammaren M, Parikka M, Parkkila S.

Molecules. 2018 Nov 8;23(11). pii: E2911. doi: 10.3390/molecules23112911. Review.

7.

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish.

Luukinen H, Hammarén MM, Vanha-Aho LM, Parikka M.

J Vis Exp. 2018 Oct 8;(140). doi: 10.3791/58299.

PMID:
30346391
8.

Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes.

Aspatwar A, Becker HM, Parvathaneni NK, Hammaren M, Svorjova A, Barker H, Supuran CT, Dubois L, Lambin P, Parikka M, Parkkila S, Winum JY.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1064-1073. doi: 10.1080/14756366.2018.1482285.

9.

Identification of protective postexposure mycobacterial vaccine antigens using an immunosuppression-based reactivation model in the zebrafish.

Myllymäki H, Niskanen M, Luukinen H, Parikka M, Rämet M.

Dis Model Mech. 2018 Mar 13;11(3). pii: dmm033175. doi: 10.1242/dmm.033175.

10.

Priming of innate antimycobacterial immunity by heat-killed Listeria monocytogenes induces sterilizing response in the adult zebrafish tuberculosis model.

Luukinen H, Hammarén MM, Vanha-Aho LM, Svorjova A, Kantanen L, Järvinen S, Luukinen BV, Dufour E, Rämet M, Hytönen VP, Parikka M.

Dis Model Mech. 2018 Jan 29;11(1). pii: dmm031658. doi: 10.1242/dmm.031658.

11.

Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models.

Al-Samadi A, Awad SA, Tuomainen K, Zhao Y, Salem A, Parikka M, Salo T.

Oncotarget. 2017 May 10;8(36):60123-60134. doi: 10.18632/oncotarget.17768. eCollection 2017 Sep 1.

12.

Identification of novel antigen candidates for a tuberculosis vaccine in the adult zebrafish (Danio rerio).

Myllymäki H, Niskanen M, Oksanen KE, Sherwood E, Ahava M, Parikka M, Rämet M.

PLoS One. 2017 Jul 25;12(7):e0181942. doi: 10.1371/journal.pone.0181942. eCollection 2017.

13.

Zebrafish as a Model Organism for the Development of Drugs for Skin Cancer.

Bootorabi F, Manouchehri H, Changizi R, Barker H, Palazzo E, Saltari A, Parikka M, Pincelli C, Aspatwar A.

Int J Mol Sci. 2017 Jul 18;18(7). pii: E1550. doi: 10.3390/ijms18071550. Review.

14.

β-CA-specific inhibitor dithiocarbamate Fc14-584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis.

Aspatwar A, Hammarén M, Koskinen S, Luukinen B, Barker H, Carta F, Supuran CT, Parikka M, Parkkila S.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):832-840. doi: 10.1080/14756366.2017.1332056.

15.

DNA vaccination boosts Bacillus Calmette-Guérin protection against mycobacterial infection in zebrafish.

Oksanen KE, Myllymäki H, Ahava MJ, Mäkinen L, Parikka M, Rämet M.

Dev Comp Immunol. 2016 Jan;54(1):89-96. doi: 10.1016/j.dci.2015.09.001. Epub 2015 Sep 9.

PMID:
26363085
16.

Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish.

Aspatwar A, Tolvanen ME, Ojanen MJ, Barker HR, Saralahti AK, Bäuerlein CA, Ortutay C, Pan P, Kuuslahti M, Parikka M, Rämet M, Parkkila S.

PLoS One. 2015 Jul 28;10(7):e0134263. doi: 10.1371/journal.pone.0134263. eCollection 2015.

17.

The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.

Ojanen MJ, Turpeinen H, Cordova ZM, Hammarén MM, Harjula SK, Parikka M, Rämet M, Pesu M.

Infect Immun. 2015 Apr;83(4):1431-42. doi: 10.1128/IAI.03135-14. Epub 2015 Jan 26.

18.

Adequate Th2-type response associates with restricted bacterial growth in latent mycobacterial infection of zebrafish.

Hammarén MM, Oksanen KE, Nisula HM, Luukinen BV, Pesu M, Rämet M, Parikka M.

PLoS Pathog. 2014 Jun 26;10(6):e1004190. doi: 10.1371/journal.ppat.1004190. eCollection 2014 Jun.

19.

Zebavidin--an avidin-like protein from zebrafish.

Taskinen B, Zmurko J, Ojanen M, Kukkurainen S, Parthiban M, Määttä JA, Leppiniemi J, Jänis J, Parikka M, Turpeinen H, Rämet M, Pesu M, Johnson MS, Kulomaa MS, Airenne TT, Hytönen VP.

PLoS One. 2013 Oct 24;8(10):e77207. doi: 10.1371/journal.pone.0077207. eCollection 2013.

20.

Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).

Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimäki A, Rämet M, Parikka M, Hytönen VP, Nykter M, Pesu M.

J Biol Chem. 2013 Dec 20;288(51):36610-23. doi: 10.1074/jbc.M113.453183. Epub 2013 Oct 31.

21.

Adult zebrafish model for pneumococcal pathogenesis.

Saralahti A, Piippo H, Parikka M, Henriques-Normark B, Rämet M, Rounioja S.

Dev Comp Immunol. 2014 Feb;42(2):345-53. doi: 10.1016/j.dci.2013.09.009. Epub 2013 Sep 25.

PMID:
24076065
22.

An adult zebrafish model for preclinical tuberculosis vaccine development.

Oksanen KE, Halfpenny NJ, Sherwood E, Harjula SK, Hammarén MM, Ahava MJ, Pajula ET, Lahtinen MJ, Parikka M, Rämet M.

Vaccine. 2013 Oct 25;31(45):5202-9. doi: 10.1016/j.vaccine.2013.08.093. Epub 2013 Sep 20.

PMID:
24055305
23.

Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish.

Aspatwar A, Tolvanen ME, Jokitalo E, Parikka M, Ortutay C, Harjula SK, Rämet M, Vihinen M, Parkkila S.

Hum Mol Genet. 2013 Feb 1;22(3):417-32. doi: 10.1093/hmg/dds438. Epub 2012 Oct 18.

PMID:
23087022
24.

Mycobacterium marinum causes a latent infection that can be reactivated by gamma irradiation in adult zebrafish.

Parikka M, Hammarén MM, Harjula SK, Halfpenny NJ, Oksanen KE, Lahtinen MJ, Pajula ET, Iivanainen A, Pesu M, Rämet M.

PLoS Pathog. 2012 Sep;8(9):e1002944. doi: 10.1371/journal.ppat.1002944. Epub 2012 Sep 27.

25.

The zebrafish as a model for paediatric diseases.

Lohi O, Parikka M, Rämet M.

Acta Paediatr. 2013 Feb;102(2):104-10. doi: 10.1111/j.1651-2227.2012.02835.x. Epub 2012 Sep 7. Review.

PMID:
22924984
26.

Adult zebrafish model of bacterial meningitis in Streptococcus agalactiae infection.

Patterson H, Saralahti A, Parikka M, Dramsi S, Trieu-Cuot P, Poyart C, Rounioja S, Rämet M.

Dev Comp Immunol. 2012 Nov;38(3):447-55. doi: 10.1016/j.dci.2012.07.007. Epub 2012 Aug 4.

PMID:
22867759
27.

SAP30L (Sin3A-associated protein 30-like) is involved in regulation of cardiac development and hematopoiesis in zebrafish embryos.

Teittinen KJ, Grönroos T, Parikka M, Junttila S, Uusimäki A, Laiho A, Korkeamäki H, Kurppa K, Turpeinen H, Pesu M, Gyenesei A, Rämet M, Lohi O.

J Cell Biochem. 2012 Dec;113(12):3843-52. doi: 10.1002/jcb.24298.

PMID:
22821512
28.

The zebrafish as a tool in leukemia research.

Teittinen KJ, Grönroos T, Parikka M, Rämet M, Lohi O.

Leuk Res. 2012 Sep;36(9):1082-8. doi: 10.1016/j.leukres.2012.06.001. Epub 2012 Jun 27. Review.

PMID:
22749067
29.

Glcci1 deficiency leads to proteinuria.

Nishibori Y, Katayama K, Parikka M, Oddsson A, Nukui M, Hultenby K, Wernerson A, He B, Ebarasi L, Raschperger E, Norlin J, Uhlén M, Patrakka J, Betsholtz C, Tryggvason K.

J Am Soc Nephrol. 2011 Nov;22(11):2037-46. doi: 10.1681/ASN.2010111147. Epub 2011 Sep 23.

30.

Defense of zebrafish embryos against Streptococcus pneumoniae infection is dependent on the phagocytic activity of leukocytes.

Rounioja S, Saralahti A, Rantala L, Parikka M, Henriques-Normark B, Silvennoinen O, Rämet M.

Dev Comp Immunol. 2012 Feb;36(2):342-8. doi: 10.1016/j.dci.2011.05.008. Epub 2011 May 31.

PMID:
21658407
31.

Cofilin regulator 14-3-3zeta is an evolutionarily conserved protein required for phagocytosis and microbial resistance.

Ulvila J, Vanha-aho LM, Kleino A, Vähä-Mäkilä M, Vuoksio M, Eskelinen S, Hultmark D, Kocks C, Hallman M, Parikka M, Rämet M.

J Leukoc Biol. 2011 May;89(5):649-59. doi: 10.1189/jlb.0410195. Epub 2011 Jan 4.

PMID:
21208897
32.

Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function.

Hyvärinen J, Parikka M, Sormunen R, Rämet M, Tryggvason K, Kivirikko KI, Myllyharju J, Koivunen P.

J Biol Chem. 2010 Dec 31;285(53):42023-32. doi: 10.1074/jbc.M110.145904. Epub 2010 Oct 15.

33.

Genome-wide RNA interference in Drosophila cells identifies G protein-coupled receptor kinase 2 as a conserved regulator of NF-kappaB signaling.

Valanne S, Myllymäki H, Kallio J, Schmid MR, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani SS, Engström Y, Silvennoinen O, Hultmark D, Parikka M, Rämet M.

J Immunol. 2010 Jun 1;184(11):6188-98. doi: 10.4049/jimmunol.1000261. Epub 2010 Apr 26.

34.

Deterministic diffractive diffusers for displays.

Parikka M, Kaikuranta T, Laakkonen P, Lautanen J, Tervo J, Honkanen M, Kuittinen M, Turunen J.

Appl Opt. 2001 May 10;40(14):2239-46.

PMID:
18357231
35.

Collagen XVIII modulation is altered during progression of oral dysplasia and carcinoma.

Väänänen A, Ylipalosaari M, Parikka M, Kainulainen T, Rehn M, Heljasvaara R, Tjäderhane L, Salo T.

J Oral Pathol Med. 2007 Jan;36(1):35-42.

PMID:
17181740
36.

Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells.

Ulvila J, Parikka M, Kleino A, Sormunen R, Ezekowitz RA, Kocks C, Rämet M.

J Biol Chem. 2006 May 19;281(20):14370-5. Epub 2006 Mar 10.

37.

Collagen XVII promotes integrin-mediated squamous cell carcinoma transmigration--a novel role for alphaIIb integrin and tirofiban.

Parikka M, Nissinen L, Kainulainen T, Bruckner-Tuderman L, Salo T, Heino J, Tasanen K.

Exp Cell Res. 2006 May 1;312(8):1431-8. Epub 2006 Feb 20.

PMID:
16487966
38.

Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases.

Heljasvaara R, Nyberg P, Luostarinen J, Parikka M, Heikkilä P, Rehn M, Sorsa T, Salo T, Pihlajaniemi T.

Exp Cell Res. 2005 Jul 15;307(2):292-304.

PMID:
15950618
39.

Coupling of light from an LED into a thin light guide by diffractive gratings.

Siitonen S, Laakkonen P, Vahimaa P, Jefimovs K, Kuittinen M, Parikka M, Mönkkönen K, Orpana A.

Appl Opt. 2004 Oct 20;43(30):5631-6.

PMID:
15534994
40.

Overexpression of TIMP-1 under the MMP-9 promoter interferes with wound healing in transgenic mice.

Salonurmi T, Parikka M, Kontusaari S, Pirilä E, Munaut C, Salo T, Tryggvason K.

Cell Tissue Res. 2004 Jan;315(1):27-37. Epub 2003 Oct 21.

41.

Alterations of collagen XVII expression during transformation of oral epithelium to dysplasia and carcinoma.

Parikka M, Kainulainen T, Tasanen K, Väänänen A, Bruckner-Tuderman L, Salo T.

J Histochem Cytochem. 2003 Jul;51(7):921-9.

PMID:
12810842
42.

Modulation of collagen synthesis and mRNA by continuous and intermittent use of topical hydrocortisone in human skin.

Nuutinen P, Riekki R, Parikka M, Salo T, Autio P, Risteli J, Oikarinen A.

Br J Dermatol. 2003 Jan;148(1):39-45.

PMID:
12534592
43.

Increased expression of collagen types I and III in human skin as a consequence of radiotherapy.

Riekki R, Parikka M, Jukkola A, Salo T, Risteli J, Oikarinen A.

Arch Dermatol Res. 2002 Jul;294(4):178-84. Epub 2002 Apr 27.

PMID:
12111348
44.

Chemically modified tetracycline (CMT-8) and estrogen promote wound healing in ovariectomized rats: effects on matrix metalloproteinase-2, membrane type 1 matrix metalloproteinase, and laminin-5 gamma2-chain.

Pirilä E, Parikka M, Ramamurthy NS, Maisi P, McClain S, Kucine A, Tervahartiala T, Prikk K, Golub LM, Salo T, Sorsa T.

Wound Repair Regen. 2002 Jan-Feb;10(1):38-51.

PMID:
11983005
45.

Altered expression of collagen XVII in ameloblastomas and basal cell carcinomas.

Parikka M, Kainulainen T, Tasanen K, Bruckner-Tuderman L, Salo T.

J Oral Pathol Med. 2001 Nov;30(10):589-95.

PMID:
11722708
46.

Expression and regulation of MMP-20 in human tongue carcinoma cells.

Väänänen A, Srinivas R, Parikka M, Palosaari H, Bartlett JD, Iwata K, Grenman R, Stenman UH, Sorsa T, Salo T.

J Dent Res. 2001 Oct;80(10):1884-9.

PMID:
11706946
47.

Prognostic factors in tongue cancer - relative importance of demographic, clinical and histopathological factors.

Kantola S, Parikka M, Jokinen K, Hyrynkangs K, Soini Y, Alho OP, Salo T.

Br J Cancer. 2000 Sep;83(5):614-9.

48.

Expression of laminin-5 in ameloblastomas and human fetal teeth.

Salo T, Kainulainen T, Parikka M, Heikinheimo K.

J Oral Pathol Med. 1999 Sep;28(8):337-42.

PMID:
10478957

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