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Items: 1 to 50 of 84

1.

Neutrophil activation in systemic capillary leak syndrome (Clarkson disease).

Xie Z, Kuhns DB, Gu X, Otu HH, Libermann TA, Gallin JI, Parikh SM, Druey KM.

J Cell Mol Med. 2019 Aug;23(8):5119-5127. doi: 10.1111/jcmm.14381. Epub 2019 Jun 18.

2.

An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna.

Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, Parikh SM, Spiegelman BM.

Cell Metab. 2019 Jul 2;30(1):190-200.e6. doi: 10.1016/j.cmet.2019.04.013. Epub 2019 May 16.

PMID:
31105043
3.

Author Correction: Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.

Zhou HL, Zhang R, Anand P, Stomberski CT, Qian Z, Hausladen A, Wang L, Rhee EP, Parikh SM, Karumanchi SA, Stamler JS.

Nature. 2019 Jun;570(7759):E23. doi: 10.1038/s41586-019-1225-0.

PMID:
31089212
4.
5.

TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance.

Lynch MR, Tran MT, Ralto KM, Zsengeller ZK, Raman V, Bhasin SS, Sun N, Chen X, Brown D, Rovira II, Taguchi K, Brooks CR, Stillman IE, Bhasin MK, Finkel T, Parikh SM.

JCI Insight. 2019 Mar 14;5. pii: 126749. doi: 10.1172/jci.insight.126749.

6.

Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.

Zhou HL, Zhang R, Anand P, Stomberski CT, Qian Z, Hausladen A, Wang L, Rhee EP, Parikh SM, Karumanchi SA, Stamler JS.

Nature. 2019 Jan;565(7737):96-100. doi: 10.1038/s41586-018-0749-z. Epub 2018 Nov 28. Erratum in: Nature. 2019 Jun;570(7759):E23.

7.

Increased synthesis of a coenzyme linked to longevity can combat disease.

Parikh SM.

Nature. 2018 Nov;563(7731):332-333. doi: 10.1038/d41586-018-07088-4. No abstract available.

PMID:
30425355
8.

Multiplexed, high-throughput measurements of cell contraction and endothelial barrier function.

Rokhzan R, Ghosh CC, Schaible N, Notbohm J, Yoshie H, Ehrlicher AJ, Higgins SJ, Zhang R, Haller H, Hardin CC, David S, Parikh SM, Krishnan R.

Lab Invest. 2019 Jan;99(1):138-145. doi: 10.1038/s41374-018-0136-2. Epub 2018 Oct 11.

9.

Decreased PGC-1α Post-Cardiopulmonary Bypass Leads to Impaired Oxidative Stress in Diabetic Patients.

Mahmood E, Jeganathan J, Feng R, Saraf M, Khabbaz K, Mahmood F, Venkatachalam S, Liu D, Chu L, Parikh SM, Matyal R.

Ann Thorac Surg. 2019 Feb;107(2):467-476. doi: 10.1016/j.athoracsur.2018.08.009. Epub 2018 Oct 3.

PMID:
30291832
10.

Serum Angiopoietin-2 Predicts Mortality and Kidney Outcomes in Decompensated Cirrhosis.

Allegretti AS, Vela Parada X, Ortiz GA, Long J, Krinsky S, Zhao S, Fuchs BC, Sojoodi M, Zhang D, Karumanchi SA, Kalim S, Nigwekar SU, Thadhani RI, Parikh SM, Chung RT.

Hepatology. 2019 Feb;69(2):729-741. doi: 10.1002/hep.30230. Epub 2019 Jan 4.

PMID:
30141205
11.

De novo NAD+ biosynthetic impairment in acute kidney injury in humans.

Poyan Mehr A, Tran MT, Ralto KM, Leaf DE, Washco V, Messmer J, Lerner A, Kher A, Kim SH, Khoury CC, Herzig SJ, Trovato ME, Simon-Tillaux N, Lynch MR, Thadhani RI, Clish CB, Khabbaz KR, Rhee EP, Waikar SS, Berg AH, Parikh SM.

Nat Med. 2018 Sep;24(9):1351-1359. doi: 10.1038/s41591-018-0138-z. Epub 2018 Aug 20.

12.

Esmolol infusion in patients with septic shock and tachycardia: a prospective, single-arm, feasibility study.

Brown SM, Beesley SJ, Lanspa MJ, Grissom CK, Wilson EL, Parikh SM, Sarge T, Talmor D, Banner-Goodspeed V, Novack V, Thompson BT, Shahul S; Esmolol to Control Adrenergic Storm in Septic Shock-ROLL-IN (ECASSS-R) study.

Pilot Feasibility Stud. 2018 Aug 3;4:132. doi: 10.1186/s40814-018-0321-5. eCollection 2018.

13.

Molecular Regulation of Acute Tie2 Suppression in Sepsis.

Thamm K, Schrimpf C, Retzlaff J, Idowu TO, van Meurs M, Zijlstra JG, Ghosh CC, Zeitvogel J, Werfel TA, Haller H, Parikh SM, David S.

Crit Care Med. 2018 Sep;46(9):e928-e936. doi: 10.1097/CCM.0000000000003269.

14.

Computer Use and Carpal Tunnel Syndrome: A Case-control Study.

Bhanderi DJ, Mishra DG, Parikh SM, Sharma DB.

Indian J Occup Environ Med. 2017 Sep-Dec;21(3):109-114. doi: 10.4103/ijoem.IJOEM_66_17.

15.

Reply.

Druey KM, Arai AE, Parikh SM.

J Allergy Clin Immunol. 2018 Apr;141(4):1540-1541. doi: 10.1016/j.jaci.2017.11.054. Epub 2018 Feb 21. No abstract available.

PMID:
29477580
16.

Tie2 protects the vasculature against thrombus formation in systemic inflammation.

Higgins SJ, De Ceunynck K, Kellum JA, Chen X, Gu X, Chaudhry SA, Schulman S, Libermann TA, Lu S, Shapiro NI, Christiani DC, Flaumenhaft R, Parikh SM.

J Clin Invest. 2018 Apr 2;128(4):1471-1484. doi: 10.1172/JCI97488. Epub 2018 Mar 5.

17.

PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury.

De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E982-E991. doi: 10.1073/pnas.1718600115. Epub 2018 Jan 17.

18.

Renal PGC1α May Be Associated with Recovery after Delayed Graft Function.

Drury ER, Zsengeller ZK, Stillman IE, Khankin EV, Pavlakis M, Parikh SM.

Nephron. 2018;138(4):303-309. doi: 10.1159/000485663. Epub 2017 Dec 21.

19.

PGC1α in the kidney.

Lynch MR, Tran MT, Parikh SM.

Am J Physiol Renal Physiol. 2018 Jan 1;314(1):F1-F8. doi: 10.1152/ajprenal.00263.2017. Epub 2017 Sep 20. Review.

20.

PPARγ-Coactivator-1α, Nicotinamide Adenine Dinucleotide and Renal Stress Resistance.

Poyan Mehr A, Parikh SM.

Nephron. 2017;137(4):253-255. doi: 10.1159/000471895. Epub 2017 Jun 8. Review.

21.

Angiopoietins and Tie2 in vascular inflammation.

Parikh SM.

Curr Opin Hematol. 2017 Sep;24(5):432-438. doi: 10.1097/MOH.0000000000000361. Review.

22.

The Angiopoietin-Tie2 Signaling Axis in Systemic Inflammation.

Parikh SM.

J Am Soc Nephrol. 2017 Jul;28(7):1973-1982. doi: 10.1681/ASN.2017010069. Epub 2017 May 2. Review.

23.

Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis.

Retzlaff J, Thamm K, Ghosh CC, Ziegler W, Haller H, Parikh SM, David S.

Sci Rep. 2017 Mar 9;7:44113. doi: 10.1038/srep44113.

24.

KLF2 and KLF4 control endothelial identity and vascular integrity.

Sangwung P, Zhou G, Nayak L, Chan ER, Kumar S, Kang DW, Zhang R, Liao X, Lu Y, Sugi K, Fujioka H, Shi H, Lapping SD, Ghosh CC, Higgins SJ, Parikh SM, Jo H, Jain MK.

JCI Insight. 2017 Feb 23;2(4):e91700. doi: 10.1172/jci.insight.91700.

25.

Idiopathic systemic capillary leak syndrome (Clarkson disease).

Druey KM, Parikh SM.

J Allergy Clin Immunol. 2017 Sep;140(3):663-670. doi: 10.1016/j.jaci.2016.10.042. Epub 2016 Dec 22. Review.

26.

Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Patients with Obstructive Sleep Apnea.

Maski MR, Thomas RJ, Karumanchi SA, Parikh SM.

PLoS One. 2016 May 5;11(5):e0154503. doi: 10.1371/journal.pone.0154503. eCollection 2016.

27.

Targeting Tie2 and the host vascular response in sepsis.

Parikh SM.

Sci Transl Med. 2016 Apr 20;8(335):335fs9. doi: 10.1126/scitranslmed.aaf5537. Review.

PMID:
27099172
28.

Mitochondria in Acute Kidney Injury.

Ralto KM, Parikh SM.

Semin Nephrol. 2016 Jan;36(1):8-16. doi: 10.1016/j.semnephrol.2016.01.005. Review.

29.

PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.

Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP, Parikh SM.

Nature. 2016 Mar 24;531(7595):528-32. doi: 10.1038/nature17184. Epub 2016 Mar 16.

30.

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.

Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z.

Nat Med. 2016 Apr;22(4):421-6. doi: 10.1038/nm.4057. Epub 2016 Mar 7.

31.

Gene control of tyrosine kinase TIE2 and vascular manifestations of infections.

Ghosh CC, David S, Zhang R, Berghelli A, Milam K, Higgins SJ, Hunter J, Mukherjee A, Wei Y, Tran M, Suber F, Kobzik L, Kain KC, Lu S, Santel A, Yano K, Guha P, Dumont DJ, Christiani DC, Parikh SM.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2472-7. doi: 10.1073/pnas.1519467113. Epub 2016 Feb 16.

32.

Cellular and Molecular Mechanisms of AKI.

Agarwal A, Dong Z, Harris R, Murray P, Parikh SM, Rosner MH, Kellum JA, Ronco C; Acute Dialysis Quality Initiative XIII Working Group.

J Am Soc Nephrol. 2016 May;27(5):1288-99. doi: 10.1681/ASN.2015070740. Epub 2016 Feb 9. Review.

33.

Mitochondrial dysfunction in inherited renal disease and acute kidney injury.

Emma F, Montini G, Parikh SM, Salviati L.

Nat Rev Nephrol. 2016 May;12(5):267-80. doi: 10.1038/nrneph.2015.214. Epub 2016 Jan 25. Review.

34.

Drug Repurposing Screen Identifies Foxo1-Dependent Angiopoietin-2 Regulation in Sepsis.

Ghosh CC, Thamm K, Berghelli AV, Schrimpf C, Maski MR, Abid T, Milam KE, Rajakumar A, Santel A, Kielstein JT, Ahmed A, Thickett D, Wang K, Chase M, Donnino MW, Aird WC, Haller H, David S, Parikh SM.

Crit Care Med. 2015 Jul;43(7):e230-40. doi: 10.1097/CCM.0000000000000993.

35.

The angiopoietin-Tie2 signaling axis in the vascular leakage of systemic inflammation.

Milam KE, Parikh SM.

Tissue Barriers. 2015 Apr 3;3(1-2):e957508. doi: 10.4161/21688362.2014.957508. eCollection 2015.

36.

Mitochondrial function and disturbances in the septic kidney.

Parikh SM, Yang Y, He L, Tang C, Zhan M, Dong Z.

Semin Nephrol. 2015 Jan;35(1):108-19. doi: 10.1016/j.semnephrol.2015.01.011. Review.

37.

Angiopoietin-1 requires oxidant signaling through p47phox to promote endothelial barrier defense.

Ghosh CC, Mukherjee A, David S, Milam KE, Hunter JT, Parikh SM.

PLoS One. 2015 Mar 11;10(3):e0119577. doi: 10.1371/journal.pone.0119577. eCollection 2015.

38.

Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar.

Aisiku O, Peters CG, De Ceunynck K, Ghosh CC, Dilks JR, Fustolo-Gunnink SF, Huang M, Dockendorff C, Parikh SM, Flaumenhaft R.

Blood. 2015 Mar 19;125(12):1976-85. doi: 10.1182/blood-2014-09-599910. Epub 2015 Jan 13.

39.

The authors reply.

Thamm K, Stiehl T, Parikh SM, David S.

Crit Care Med. 2015 Jan;43(1):e32-3. doi: 10.1097/CCM.0000000000000736. No abstract available.

40.

Inflammatory Markers of the Systemic Capillary Leak Syndrome (Clarkson Disease).

Xie Z, Chan E, Yin Y, Ghosh CC, Wisch L, Nelson C, Young M, Parikh SM, Druey KM.

J Clin Cell Immunol. 2014;5:1000213.

41.

Mitochondrial biogenesis in the acutely injured kidney.

Tran M, Parikh SM.

Nephron Clin Pract. 2014;127(1-4):42-5. doi: 10.1159/000363715. Epub 2014 Sep 24. Review.

42.

Lung-targeted RNA interference against angiopoietin-2 ameliorates multiple organ dysfunction and death in sepsis.

Stiehl T, Thamm K, Kaufmann J, Schaeper U, Kirsch T, Haller H, Santel A, Ghosh CC, Parikh SM, David S.

Crit Care Med. 2014 Oct;42(10):e654-62. doi: 10.1097/CCM.0000000000000524.

PMID:
25083983
43.

Mechanistic classification of the systemic capillary leak syndrome: Clarkson disease.

Xie Z, Ghosh CC, Parikh SM, Druey KM.

Am J Respir Crit Care Med. 2014 May 1;189(9):1145-7. doi: 10.1164/rccm.201310-1746LE. No abstract available.

44.

The planning, execution, and evaluation of a mass prophylaxis full-scale exercise in cook county, IL.

Kilianski A, O'Rourke AT, Carlson CL, Parikh SM, Shipman-Amuwo F.

Biosecur Bioterror. 2014 Mar-Apr;12(2):106-16. doi: 10.1089/bsp.2013.0089. Epub 2014 Apr 3.

PMID:
24697783
45.

Moving forward in sepsis research.

Karumanchi SA, Parikh SM.

Am J Respir Crit Care Med. 2013 Nov 15;188(10):1264-5. doi: 10.1164/rccm.201305-0810LE. No abstract available.

46.

Therapeutic targeting of the mitochondrial dysfunction in septic acute kidney injury.

Parikh SM.

Curr Opin Crit Care. 2013 Dec;19(6):554-9. doi: 10.1097/MCC.0000000000000038. Review.

47.

The vasculature in diabetic nephropathy: all tied up?

Maski MR, Parikh SM.

J Am Soc Nephrol. 2014 Jan;25(1):1-3. doi: 10.1681/ASN.2013090966. Epub 2013 Oct 10. No abstract available.

48.

Clinical differences between younger and older adults with HIV/AIDS starting antiretroviral therapy in Uganda and Zimbabwe: a secondary analysis of the DART trial.

Parikh SM, Obuku EA, Walker SA, Semeere AS, Auerbach BJ, Hakim JG, Mayanja-Kizza H, Mugyenyi PN, Salata RA, Kityo CM; DART Trial Team.

PLoS One. 2013 Oct 2;8(10):e76158. doi: 10.1371/journal.pone.0076158. eCollection 2013.

49.

Dysregulation of the angiopoietin-Tie-2 axis in sepsis and ARDS.

Parikh SM.

Virulence. 2013 Aug 15;4(6):517-24. doi: 10.4161/viru.24906. Epub 2013 May 7. Review.

50.

Determinants of clinician knowledge on aging and HIV/AIDS: a survey of practitioners and policy makers in Kampala District, Uganda.

Obuku EA, Parikh SM, Nankabirwa V, Kakande NI, Mafigiri DK, Mayanja-Kizza H, Kityo CM, Mugyenyi PN, Salata RA.

PLoS One. 2013;8(2):e57028. doi: 10.1371/journal.pone.0057028. Epub 2013 Feb 28.

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