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Items: 32


United States National Trends in Mortality, Length of Stay (LOS) and Associated Costs of Cognitive Impairment in HIV Population from 2005 to 2014.

Patel S, Parikh NU, Aalinkeel R, Reynolds JL, Dmello R, Schwartz SA, Mahajan SD.

AIDS Behav. 2018 Oct;22(10):3198-3208. doi: 10.1007/s10461-018-2128-z.


Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway.

Sharikova AV, Quaye E, Park JY, Maloney MC, Desta H, Thiyagarajan R, Seldeen KL, Parikh NU, Sandhu P, Khmaladze A, Troen BR, Schwartz SA, Mahajan SD.

J Neuroimmune Pharmacol. 2018 Sep;13(3):396-411. doi: 10.1007/s11481-018-9787-4. Epub 2018 Apr 11.


Immunomodulatory Role of Complement Proteins in the Neuropathology Associated with Opiate Abuse and HIV-1 Co-Morbidity.

Mahajan SD, Aalinkeel R, Parikh NU, Jacob A, Cwiklinski K, Sandhu P, Le K, Loftus AW, Schwartz SA, Quigg RJ, Alexander JJ.

Immunol Invest. 2017 Nov;46(8):816-832. doi: 10.1080/08820139.2017.1371891.


Role of Galectin-3 in the pathophysiology underlying allergic lung inflammation in a tissue inhibitor of metalloproteinases 1 knockout model of murine asthma.

Mammen MJ, Sands MF, Abou-Jaoude E, Aalinkeel R, Reynolds JL, Parikh NU, Sharma U, Schwartz SA, Mahajan SD.

Immunology. 2018 Mar;153(3):387-396. doi: 10.1111/imm.12848. Epub 2017 Nov 7.


Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer.

Parseghian CM, Parikh NU, Wu JY, Jiang ZQ, Henderson L, Tian F, Pastor B, Ychou M, Raghav K, Dasari A, Fogelman DR, Katsiampoura AD, Menter DG, Wolff RA, Eng C, Overman MJ, Thierry AR, Gallick GE, Kopetz S.

Clin Cancer Res. 2017 Aug 1;23(15):4146-4154. doi: 10.1158/1078-0432.CCR-16-3138. Epub 2017 Mar 9.


Galectin-1 Reduces Neuroinflammation via Modulation of Nitric Oxide-Arginase Signaling in HIV-1 Transfected Microglia: a Gold Nanoparticle-Galectin-1 "Nanoplex" a Possible Neurotherapeutic?

Aalinkeel R, Mangum CS, Abou-Jaoude E, Reynolds JL, Liu M, Sundquist K, Parikh NU, Chaves LD, Mammen MJ, Schwartz SA, Mahajan SD.

J Neuroimmune Pharmacol. 2017 Mar;12(1):133-151. doi: 10.1007/s11481-016-9723-4. Epub 2016 Dec 27.


Identification of Bone-Derived Factors Conferring De Novo Therapeutic Resistance in Metastatic Prostate Cancer.

Lee YC, Lin SC, Yu G, Cheng CJ, Liu B, Liu HC, Hawke DH, Parikh NU, Varkaris A, Corn P, Logothetis C, Satcher RL, Yu-Lee LY, Gallick GE, Lin SH.

Cancer Res. 2015 Nov 15;75(22):4949-59. doi: 10.1158/0008-5472.CAN-15-1215. Epub 2015 Nov 3.


Chitosan nanoparticle-mediated delivery of miRNA-34a decreases prostate tumor growth in the bone and its expression induces non-canonical autophagy.

Gaur S, Wen Y, Song JH, Parikh NU, Mangala LS, Blessing AM, Ivan C, Wu SY, Varkaris A, Shi Y, Lopez-Berestein G, Frigo DE, Sood AK, Gallick GE.

Oncotarget. 2015 Oct 6;6(30):29161-77. doi: 10.18632/oncotarget.4971.


Integrating Murine and Clinical Trials with Cabozantinib to Understand Roles of MET and VEGFR2 as Targets for Growth Inhibition of Prostate Cancer.

Varkaris A, Corn PG, Parikh NU, Efstathiou E, Song JH, Lee YC, Aparicio A, Hoang AG, Gaur S, Thorpe L, Maity SN, Bar Eli M, Czerniak BA, Shao Y, Alauddin M, Lin SH, Logothetis CJ, Gallick GE.

Clin Cancer Res. 2016 Jan 1;22(1):107-21. doi: 10.1158/1078-0432.CCR-15-0235. Epub 2015 Aug 13.


Galectin-1 suppresses methamphetamine induced neuroinflammation in human brain microvascular endothelial cells: Neuroprotective role in maintaining blood brain barrier integrity.

Parikh NU, Aalinkeel R, Reynolds JL, Nair BB, Sykes DE, Mammen MJ, Schwartz SA, Mahajan SD.

Brain Res. 2015 Oct 22;1624:175-187. doi: 10.1016/j.brainres.2015.07.033. Epub 2015 Jul 30.


C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus.

Mahajan SD, Parikh NU, Woodruff TM, Jarvis JN, Lopez M, Hennon T, Cunningham P, Quigg RJ, Schwartz SA, Alexander JJ.

Immunology. 2015 Sep;146(1):130-43. doi: 10.1111/imm.12489. Epub 2015 Jul 15.


Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells.

Chatterji T, Varkaris AS, Parikh NU, Song JH, Cheng CJ, Schweppe RE, Alexander S, Davis JW, Troncoso P, Friedl P, Kuang J, Lin SH, Gallick GE.

Oncotarget. 2015 Apr 30;6(12):10175-94.


Ligand-independent activation of MET through IGF-1/IGF-1R signaling.

Varkaris A, Gaur S, Parikh NU, Song JH, Dayyani F, Jin JK, Logothetis CJ, Gallick GE.

Int J Cancer. 2013 Oct 1;133(7):1536-46. doi: 10.1002/ijc.28169. Epub 2013 Apr 17.


Combined Inhibition of IGF-1R/IR and Src family kinases enhances antitumor effects in prostate cancer by decreasing activated survival pathways.

Dayyani F, Parikh NU, Varkaris AS, Song JH, Moorthy S, Chatterji T, Maity SN, Wolfe AR, Carboni JM, Gottardis MM, Logothetis CJ, Gallick GE.

PLoS One. 2012;7(12):e51189. doi: 10.1371/journal.pone.0051189. Epub 2012 Dec 26.


Dasatinib inhibits both osteoclast activation and prostate cancer PC-3-cell-induced osteoclast formation.

Araujo JC, Poblenz A, Corn P, Parikh NU, Starbuck MW, Thompson JT, Lee F, Logothetis CJ, Darnay BG.

Cancer Biol Ther. 2009 Nov;8(22):2153-9. Epub 2009 Nov 8.


Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress.

Kopetz S, Lesslie DP, Dallas NA, Park SI, Johnson M, Parikh NU, Kim MP, Abbruzzese JL, Ellis LM, Chandra J, Gallick GE.

Cancer Res. 2009 May 1;69(9):3842-9. doi: 10.1158/0008-5472.CAN-08-2246. Epub 2009 Apr 21.


Development and characterization of gemcitabine-resistant pancreatic tumor cells.

Shah AN, Summy JM, Zhang J, Park SI, Parikh NU, Gallick GE.

Ann Surg Oncol. 2007 Dec;14(12):3629-37. Epub 2007 Oct 2.


Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells.

Herynk MH, Zhang J, Parikh NU, Gallick GE.

J Exp Ther Oncol. 2007;6(3):205-17.


Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer.

Landen CN Jr, Lu C, Han LY, Coffman KT, Bruckheimer E, Halder J, Mangala LS, Merritt WM, Lin YG, Gao C, Schmandt R, Kamat AA, Li Y, Thaker P, Gershenson DM, Parikh NU, Gallick GE, Kinch MS, Sood AK.

J Natl Cancer Inst. 2006 Nov 1;98(21):1558-70.


Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases.

Lesslie DP, Summy JM, Parikh NU, Fan F, Trevino JG, Sawyer TK, Metcalf CA, Shakespeare WC, Hicklin DJ, Ellis LM, Gallick GE.

Br J Cancer. 2006 Jun 5;94(11):1710-7.


Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.

Trevino JG, Summy JM, Lesslie DP, Parikh NU, Hong DS, Lee FY, Donato NJ, Abbruzzese JL, Baker CH, Gallick GE.

Am J Pathol. 2006 Mar;168(3):962-72.


CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation.

Cabioglu N, Summy J, Miller C, Parikh NU, Sahin AA, Tuzlali S, Pumiglia K, Gallick GE, Price JE.

Cancer Res. 2005 Aug 1;65(15):6493-7.


Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor.

Bauer TW, Fan F, Liu W, Johnson M, Parikh NU, Parry GC, Callahan J, Mazar AP, Gallick GE, Ellis LM.

Ann Surg. 2005 May;241(5):748-56; discussion 756-8.


Combination of an SRC kinase inhibitor with a novel pharmacological antagonist of the urokinase receptor diminishes in vitro colon cancer invasiveness.

Boyd DD, Wang H, Avila H, Parikh NU, Kessler H, Magdolen V, Gallick GE.

Clin Cancer Res. 2004 Feb 15;10(4):1545-55.


Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells.

Herynk MH, Stoeltzing O, Reinmuth N, Parikh NU, Abounader R, Laterra J, Radinsky R, Ellis LM, Gallick GE.

Cancer Res. 2003 Jun 1;63(11):2990-6.


Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers.

Wiener JR, Windham TC, Estrella VC, Parikh NU, Thall PF, Deavers MT, Bast RC, Mills GB, Gallick GE.

Gynecol Oncol. 2003 Jan;88(1):73-9.


Src activation regulates anoikis in human colon tumor cell lines.

Windham TC, Parikh NU, Siwak DR, Summy JM, McConkey DJ, Kraker AJ, Gallick GE.

Oncogene. 2002 Nov 7;21(51):7797-807.


Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells.

Davies MA, Kim SJ, Parikh NU, Dong Z, Bucana CD, Gallick GE.

Clin Cancer Res. 2002 Jun;8(6):1904-14.


Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src.

Ellis LM, Staley CA, Liu W, Fleming RY, Parikh NU, Bucana CD, Gallick GE.

J Biol Chem. 1998 Jan 9;273(2):1052-7.


Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by activity of src kinase.

Fleming RY, Ellis LM, Parikh NU, Liu W, Staley CA, Gallick GE.

Surgery. 1997 Aug;122(2):501-7.


Effect of herbimycin A on growth and pp60c-src activity in human colon tumor cell lines.

Garcia R, Parikh NU, Saya H, Gallick GE.

Oncogene. 1991 Nov;6(11):1983-9.


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