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Items: 1 to 50 of 556

1.

Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop.

Misra MK, Augusto DG, Martin GM, Nemat-Gorgani N, Sauter J, Hofmann JA, Traherne JA, González-Quezada B, Gorodezky C, Bultitude WP, Marin W, Vierra-Green C, Anderson KM, Balas A, Caro-Oleas JL, Cisneros E, Colucci F, Dandekar R, Elfishawi SM, Fernández-Viña MA, Fouda M, González-Fernández R, Große A, Herrero-Mata MJ, Hollenbach SQ, Marsh SGE, Mentzer A, Middleton D, Moffett A, Moreno-Hidalgo MA, Mossallam GI, Nakimuli A, Oksenberg JR, Oppenheimer SJ, Parham P, Petzl-Erler ML, Planelles D, Sánchez-García F, Sánchez-Gordo F, Schmidt AH, Trowsdale J, Vargas LB, Vicario JL, Vilches C, Norman PJ, Hollenbach JA.

Hum Immunol. 2018 Oct 12. pii: S0198-8859(18)30925-X. doi: 10.1016/j.humimm.2018.10.003. [Epub ahead of print] Review.

PMID:
30321631
2.

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia.

Huhn O, Chazara O, Ivarsson MA, Retière C, Venkatesan TC, Norman PJ, Hilton HG, Jayaraman J, Traherne JA, Trowsdale J, Ito M, Kling C, Parham P, Ghadially H, Moffett A, Sharkey AM, Colucci F.

J Immunol. 2018 Sep 24. pii: ji1800860. doi: 10.4049/jimmunol.1800860. [Epub ahead of print]

PMID:
30249807
3.

KIR Donor Selection: Feasibility in Identifying better Donors.

Weisdorf D, Cooley S, Wang T, Trachtenberg E, Haagenson MD, Vierra-Green C, Spellman S, Spahn A, Vogel J, Kobusingye H, Fehninger T, Woolfrey A, Devine S, Ross M, Waller EK, Sobecks R, Parham P, Guethlein LA, Marsh SGE, Miller J; participating center writing committee.

Biol Blood Marrow Transplant. 2018 Aug 24. pii: S1083-8791(18)30493-2. doi: 10.1016/j.bbmt.2018.08.022. [Epub ahead of print]

PMID:
30149149
4.

Nomenclature for the KIR of non-human species.

Robinson J, Guethlein LA, Maccari G, Blokhuis J, Bimber BN, de Groot NG, Sanderson ND, Abi-Rached L, Walter L, Bontrop RE, Hammond JA, Marsh SGE, Parham P.

Immunogenetics. 2018 Sep;70(9):571-583. doi: 10.1007/s00251-018-1064-4. Epub 2018 Jun 4.

5.

Molecular definition of the transplantation antigens.

Parham P.

FEBS J. 2018 Aug;285(15):2728-2745. doi: 10.1111/febs.14474. Epub 2018 May 1. Review.

PMID:
29673068
6.

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa.

Nemat-Gorgani N, Hilton HG, Henn BM, Lin M, Gignoux CR, Myrick JW, Werely CJ, Granka JM, Möller M, Hoal EG, Yawata M, Yawata N, Boelen L, Asquith B, Parham P, Norman PJ.

J Immunol. 2018 Apr 15;200(8):2640-2655. doi: 10.4049/jimmunol.1701780. Epub 2018 Mar 16.

PMID:
29549179
7.

Genetics of Natural Killer Cells in Human Health, Disease, and Survival.

Parham P, Guethlein LA.

Annu Rev Immunol. 2018 Apr 26;36:519-548. doi: 10.1146/annurev-immunol-042617-053149. Epub 2018 Feb 2.

PMID:
29394121
8.

Strategies to activate NK cells to prevent relapse and induce remission following hematopoietic stem cell transplantation.

Cooley S, Parham P, Miller JS.

Blood. 2018 Mar 8;131(10):1053-1062. doi: 10.1182/blood-2017-08-752170. Epub 2018 Jan 22. Review.

PMID:
29358179
9.

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.

Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK, Lifson JD, Fellay J, Deeks SG, Martin JN, Goedert JJ, Wolinsky SM, Michael NL, Kirk GD, Buchbinder S, Haas D, Ndung'u T, Goulder P, Parham P, Walker BD, Carlson JM, Carrington M.

Science. 2018 Jan 5;359(6371):86-90. doi: 10.1126/science.aam8825. Epub 2018 Jan 4.

10.

Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage.

Pugh JL, Nemat-Gorgani N, Norman PJ, Guethlein LA, Parham P.

J Immunol. 2018 Feb 1;200(3):1146-1158. doi: 10.4049/jimmunol.1700542. Epub 2017 Dec 20.

PMID:
29263215
11.

Class I HLA haplotypes form two schools that educate NK cells in different ways.

Horowitz A, Djaoud Z, Nemat-Gorgani N, Blokhuis J, Hilton HG, Béziat V, Malmberg KJ, Norman PJ, Guethlein LA, Parham P.

Sci Immunol. 2016 Sep 9;1(3):eaag1672. doi: 10.1126/sciimmunol.aag1672. Epub 2016 Sep 9.

PMID:
28783683
12.

Missing or altered self: human NK cell receptors that recognize HLA-C.

Hilton HG, Parham P.

Immunogenetics. 2017 Aug;69(8-9):567-579. doi: 10.1007/s00251-017-1001-y. Epub 2017 Jul 10. Review.

13.

KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans.

Blokhuis JH, Hilton HG, Guethlein LA, Norman PJ, Nemat-Gorgani N, Nakimuli A, Chazara O, Moffett A, Parham P.

Immun Inflamm Dis. 2017 Dec;5(4):461-468. doi: 10.1002/iid3.178. Epub 2017 Jul 6.

14.

Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles.

Robinson J, Guethlein LA, Cereb N, Yang SY, Norman PJ, Marsh SGE, Parham P.

PLoS Genet. 2017 Jun 26;13(6):e1006862. doi: 10.1371/journal.pgen.1006862. eCollection 2017 Jun.

15.

The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands.

Hilton HG, McMurtrey CP, Han AS, Djaoud Z, Guethlein LA, Blokhuis JH, Pugh JL, Goyos A, Horowitz A, Buchli R, Jackson KW, Bardet W, Bushnell DA, Robinson PJ, Mendoza JL, Birnbaum ME, Nielsen M, Garcia KC, Hildebrand WH, Parham P.

Cell Rep. 2017 May 16;19(7):1394-1405. doi: 10.1016/j.celrep.2017.04.059.

16.

Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and γδ T cells.

Djaoud Z, Guethlein LA, Horowitz A, Azzi T, Nemat-Gorgani N, Olive D, Nadal D, Norman PJ, Münz C, Parham P.

J Exp Med. 2017 Jun 5;214(6):1827-1841. doi: 10.1084/jem.20161017. Epub 2017 May 3.

17.

A large-scale stochastic spatiotemporal model for Aedes albopictus-borne chikungunya epidemiology.

Erguler K, Chandra NL, Proestos Y, Lelieveld J, Christophides GK, Parham PE.

PLoS One. 2017 Mar 31;12(3):e0174293. doi: 10.1371/journal.pone.0174293. eCollection 2017.

18.

Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.

Norman PJ, Norberg SJ, Guethlein LA, Nemat-Gorgani N, Royce T, Wroblewski EE, Dunn T, Mann T, Alicata C, Hollenbach JA, Chang W, Shults Won M, Gunderson KL, Abi-Rached L, Ronaghi M, Parham P.

Genome Res. 2017 May;27(5):813-823. doi: 10.1101/gr.213538.116. Epub 2017 Mar 30.

19.

Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B.

Wroblewski EE, Guethlein LA, Norman PJ, Li Y, Shaw CM, Han AS, Ndjango JN, Ahuka-Mundeke S, Georgiev AV, Peeters M, Hahn BH, Parham P.

J Immunol. 2017 May 1;198(9):3480-3493. doi: 10.4049/jimmunol.1601955. Epub 2017 Mar 27.

20.

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes.

Guethlein LA, Norman PJ, Heijmans CM, de Groot NG, Hilton HG, Babrzadeh F, Abi-Rached L, Bontrop RE, Parham P.

J Immunol. 2017 Apr 15;198(8):3157-3169. doi: 10.4049/jimmunol.1602163. Epub 2017 Mar 6.

21.

Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C.

Hilton HG, Blokhuis JH, Guethlein LA, Norman PJ, Parham P.

J Immunol. 2017 Mar 1;198(5):1961-1973. doi: 10.4049/jimmunol.1601835. Epub 2017 Jan 25.

22.

Class I HLA haplotypes form two schools that educate NK cells in different ways.

Horowitz A, Djaoud Z, Nemat-Gorgani N, Blokhuis J, Hilton HG, Béziat V, Malmberg KJ, Norman PJ, Guethlein LA, Parham P.

Sci Immunol. 2016 Sep;1(3). pii: eaag1672. Epub 2016 Sep 9.

23.

How the codfish changed its immune system.

Parham P.

Nat Genet. 2016 Sep 28;48(10):1103-4. doi: 10.1038/ng.3684.

PMID:
27681288
24.

HLA class I variation in Iranian Lur and Kurd populations: high haplotype and allotype diversity with an abundance of KIR ligands.

Ashouri E, Norman PJ, Guethlein LA, Han AS, Nemat-Gorgani N, Norberg SJ, Ghaderi A, Parham P.

HLA. 2016 Sep;88(3):87-99. doi: 10.1111/tan.12852. Epub 2016 Aug 24.

25.

Clathrin light chains' role in selective endocytosis influences antibody isotype switching.

Wu S, Majeed SR, Evans TM, Camus MD, Wong NM, Schollmeier Y, Park M, Muppidi JR, Reboldi A, Parham P, Cyster JG, Brodsky FM.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9816-21. doi: 10.1073/pnas.1611189113. Epub 2016 Aug 18.

26.

Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution.

Penman BS, Moffett A, Chazara O, Gupta S, Parham P.

Immunogenetics. 2016 Nov;68(10):755-764. Epub 2016 Aug 12.

27.

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.

Norman PJ, Hollenbach JA, Nemat-Gorgani N, Marin WM, Norberg SJ, Ashouri E, Jayaraman J, Wroblewski EE, Trowsdale J, Rajalingam R, Oksenberg JR, Chiaroni J, Guethlein LA, Traherne JA, Ronaghi M, Parham P.

Am J Hum Genet. 2016 Aug 4;99(2):375-91. doi: 10.1016/j.ajhg.2016.06.023.

28.

Correction: Structural Perturbations to Population Skeletons: Transient Dynamics, Coexistence of Attractors and the Rarity of Chaos.

Singh BK, Parham PE, Hu CK.

PLoS One. 2016 Jun 10;11(6):e0157617. doi: 10.1371/journal.pone.0157617. eCollection 2016.

29.

Donor KIR B Genotype Improves Progression-Free Survival of Non-Hodgkin Lymphoma Patients Receiving Unrelated Donor Transplantation.

Bachanova V, Weisdorf DJ, Wang T, Marsh SGE, Trachtenberg E, Haagenson MD, Spellman SR, Ladner M, Guethlein LA, Parham P, Miller JS, Cooley SA.

Biol Blood Marrow Transplant. 2016 Sep;22(9):1602-1607. doi: 10.1016/j.bbmt.2016.05.016. Epub 2016 May 21.

30.

Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1.

Alicata C, Pende D, Meazza R, Canevali P, Loiacono F, Bertaina A, Locatelli F, Nemat-Gorgani N, Guethlein LA, Parham P, Moretta L, Moretta A, Bottino C, Norman PJ, Falco M.

Eur J Immunol. 2016 Jun;46(6):1511-7. doi: 10.1002/eji.201546236.

31.

Description of the novel KIR2DL4*035 allele identified using high-throughput sequencing.

Alicata C, Bottino C, Guethlein LA, Parham P, Norman PJ.

HLA. 2016 Mar;87(3):191-3. doi: 10.1111/tan.12761. Epub 2016 Feb 24.

PMID:
26917249
32.

Large-Scale Modelling of the Environmentally-Driven Population Dynamics of Temperate Aedes albopictus (Skuse).

Erguler K, Smith-Unna SE, Waldock J, Proestos Y, Christophides GK, Lelieveld J, Parham PE.

PLoS One. 2016 Feb 12;11(2):e0149282. doi: 10.1371/journal.pone.0149282. eCollection 2016.

33.

Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches.

Hughes D, Charles J, Dawoud D, Edwards RT, Holmes E, Jones C, Parham P, Plumpton C, Ridyard C, Lloyd-Williams H, Wood E, Yeo ST.

Pharmacoeconomics. 2016 May;34(5):447-61. doi: 10.1007/s40273-015-0371-y. Review.

PMID:
26753558
34.

Complex MHC Class I Gene Transcription Profiles and Their Functional Impact in Orangutans.

de Groot NG, Heijmans CM, van der Wiel MK, Blokhuis JH, Mulder A, Guethlein LA, Doxiadis GG, Claas FH, Parham P, Bontrop RE.

J Immunol. 2016 Jan 15;196(2):750-8. doi: 10.4049/jimmunol.1500820. Epub 2015 Dec 18.

35.

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation.

Horowitz A, Guethlein LA, Nemat-Gorgani N, Norman PJ, Cooley S, Miller JS, Parham P.

J Immunol. 2015 Nov 1;195(9):4524-36. doi: 10.4049/jimmunol.1401990. Epub 2015 Sep 28.

36.

Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing.

Mack SJ, Milius RP, Gifford BD, Sauter J, Hofmann J, Osoegawa K, Robinson J, Groeneweg M, Turenchalk GS, Adai A, Holcomb C, Rozemuller EH, Penning MT, Heuer ML, Wang C, Salit ML, Schmidt AH, Parham PR, Müller C, Hague T, Fischer G, Fernandez-Viňa M, Hollenbach JA, Norman PJ, Maiers M.

Hum Immunol. 2015 Dec;76(12):954-62. doi: 10.1016/j.humimm.2015.09.011. Epub 2015 Sep 25.

37.

Larval and adult environmental temperatures influence the adult reproductive traits of Anopheles gambiae s.s.

Christiansen-Jucht CD, Parham PE, Saddler A, Koella JC, Basáñez MG.

Parasit Vectors. 2015 Sep 17;8:456. doi: 10.1186/s13071-015-1053-5.

38.

A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I Molecule.

Goyos A, Guethlein LA, Horowitz A, Hilton HG, Gleimer M, Brodsky FM, Parham P.

J Immunol. 2015 Oct 15;195(8):3725-36. doi: 10.4049/jimmunol.1500397. Epub 2015 Sep 14.

39.

Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes.

Hilton HG, Guethlein LA, Goyos A, Nemat-Gorgani N, Bushnell DA, Norman PJ, Parham P.

J Immunol. 2015 Oct 1;195(7):3160-70. doi: 10.4049/jimmunol.1501358. Epub 2015 Aug 26.

40.

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

Hilton HG, Norman PJ, Nemat-Gorgani N, Goyos A, Hollenbach JA, Henn BM, Gignoux CR, Guethlein LA, Parham P.

PLoS Genet. 2015 Aug 20;11(8):e1005439. doi: 10.1371/journal.pgen.1005439. eCollection 2015 Aug.

41.

Race, Ethnicity and Ancestry in Unrelated Transplant Matching for the National Marrow Donor Program: A Comparison of Multiple Forms of Self-Identification with Genetics.

Hollenbach JA, Saperstein A, Albrecht M, Vierra-Green C, Parham P, Norman PJ, Maiers M.

PLoS One. 2015 Aug 19;10(8):e0135960. doi: 10.1371/journal.pone.0135960. eCollection 2015.

42.

Co-evolution of MHC class I and variable NK cell receptors in placental mammals.

Guethlein LA, Norman PJ, Hilton HG, Parham P.

Immunol Rev. 2015 Sep;267(1):259-82. doi: 10.1111/imr.12326. Review.

43.

Co-evolution of lymphocyte receptors with MHC class I.

Parham P.

Immunol Rev. 2015 Sep;267(1):1-5. doi: 10.1111/imr.12338. No abstract available.

PMID:
26284467
44.

Chimpanzee susceptibility to hepatitis C virus infection correlates with presence of Pt-KIR3DS2 and Pt-KIR2DL9: paired activating and inhibitory natural killer cell receptors.

Abi-Rached L, Guethlein LA, Norman PJ, Parham P.

Immunogenetics. 2015 Oct;67(10):625-8. doi: 10.1007/s00251-015-0863-0. Epub 2015 Aug 12.

45.

Very long haplotype tracts characterized at high resolution from HLA homozygous cell lines.

Norman PJ, Norberg SJ, Nemat-Gorgani N, Royce T, Hollenbach JA, Shults Won M, Guethlein LA, Gunderson KL, Ronaghi M, Parham P.

Immunogenetics. 2015 Sep;67(9):479-85. doi: 10.1007/s00251-015-0857-y. Epub 2015 Jul 22.

46.

POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.

Raghavan M, Steinrücken M, Harris K, Schiffels S, Rasmussen S, DeGiorgio M, Albrechtsen A, Valdiosera C, Ávila-Arcos MC, Malaspinas AS, Eriksson A, Moltke I, Metspalu M, Homburger JR, Wall J, Cornejo OE, Moreno-Mayar JV, Korneliussen TS, Pierre T, Rasmussen M, Campos PF, de Barros Damgaard P, Allentoft ME, Lindo J, Metspalu E, Rodríguez-Varela R, Mansilla J, Henrickson C, Seguin-Orlando A, Malmström H, Stafford T Jr, Shringarpure SS, Moreno-Estrada A, Karmin M, Tambets K, Bergström A, Xue Y, Warmuth V, Friend AD, Singarayer J, Valdes P, Balloux F, Leboreiro I, Vera JL, Rangel-Villalobos H, Pettener D, Luiselli D, Davis LG, Heyer E, Zollikofer CPE, Ponce de León MS, Smith CI, Grimes V, Pike KA, Deal M, Fuller BT, Arriaza B, Standen V, Luz MF, Ricaut F, Guidon N, Osipova L, Voevoda MI, Posukh OL, Balanovsky O, Lavryashina M, Bogunov Y, Khusnutdinova E, Gubina M, Balanovska E, Fedorova S, Litvinov S, Malyarchuk B, Derenko M, Mosher MJ, Archer D, Cybulski J, Petzelt B, Mitchell J, Worl R, Norman PJ, Parham P, Kemp BM, Kivisild T, Tyler-Smith C, Sandhu MS, Crawford M, Villems R, Smith DG, Waters MR, Goebel T, Johnson JR, Malhi RS, Jakobsson M, Meltzer DJ, Manica A, Durbin R, Bustamante CD, Song YS, Nielsen R, Willerslev E.

Science. 2015 Aug 21;349(6250):aab3884. doi: 10.1126/science.aab3884. Epub 2015 Jul 21.

47.

The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay.

Hilton HG, Moesta AK, Guethlein LA, Blokhuis J, Parham P, Norman PJ.

J Immunol Methods. 2015 Oct;425:79-87. doi: 10.1016/j.jim.2015.06.012. Epub 2015 Jun 19.

48.

Adaptive Natural Killer Cell and Killer Cell Immunoglobulin-Like Receptor-Expressing T Cell Responses are Induced by Cytomegalovirus and Are Associated with Protection against Cytomegalovirus Reactivation after Allogeneic Donor Hematopoietic Cell Transplantation.

Davis ZB, Cooley SA, Cichocki F, Felices M, Wangen R, Luo X, DeFor TE, Bryceson YT, Diamond DJ, Brunstein C, Blazar BR, Wagner JE, Weisdorf DJ, Horowitz A, Guethlein LA, Parham P, Verneris MR, Miller JS.

Biol Blood Marrow Transplant. 2015 Sep;21(9):1653-62. doi: 10.1016/j.bbmt.2015.05.025. Epub 2015 Jun 6.

49.

Modelling Anopheles gambiae s.s. Population Dynamics with Temperature- and Age-Dependent Survival.

Christiansen-Jucht C, Erguler K, Shek CY, Basáñez MG, Parham PE.

Int J Environ Res Public Health. 2015 May 28;12(6):5975-6005. doi: 10.3390/ijerph120605975.

50.

Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz.

Wroblewski EE, Norman PJ, Guethlein LA, Rudicell RS, Ramirez MA, Li Y, Hahn BH, Pusey AE, Parham P.

PLoS Biol. 2015 May 28;13(5):e1002144. doi: 10.1371/journal.pbio.1002144. eCollection 2015 May.

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