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Items: 1 to 50 of 566

1.

KIR3DL1/S1 Allotypes Contribute Differentially to the Development of Behçet Disease.

Petrushkin H, Norman PJ, Lougee E, Parham P, Wallace GR, Stanford MR, Fortune F.

J Immunol. 2019 Aug 12. pii: ji1801178. doi: 10.4049/jimmunol.1801178. [Epub ahead of print]

PMID:
31405953
2.

A natural killer cell receptor takes sharp aim at the world of bacteria.

Parham P.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12601-12603. doi: 10.1073/pnas.1907937116. Epub 2019 Jun 7. No abstract available.

PMID:
31175150
3.

Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism.

Fumagalli M, Camus SM, Diekmann Y, Burke A, Camus MD, Norman PJ, Joseph A, Abi-Rached L, Benazzo A, Rasteiro R, Mathieson I, Topf M, Parham P, Thomas MG, Brodsky FM.

Elife. 2019 Jun 4;8. pii: e41517. doi: 10.7554/eLife.41517.

4.

Diversity of KIR, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans.

Nemat-Gorgani N, Guethlein LA, Henn BM, Norberg SJ, Chiaroni J, Sikora M, Quintana-Murci L, Mountain JL, Norman PJ, Parham P.

J Immunol. 2019 May 1;202(9):2636-2647. doi: 10.4049/jimmunol.1801586. Epub 2019 Mar 27.

PMID:
30918042
5.

A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease.

Hollenbach JA, Norman PJ, Creary LE, Damotte V, Montero-Martin G, Caillier S, Anderson KM, Misra MK, Nemat-Gorgani N, Osoegawa K, Santaniello A, Renschen A, Marin WM, Dandekar R, Parham P, Tanner CM, Hauser SL, Fernandez-Viña M, Oksenberg JR.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7419-7424. doi: 10.1073/pnas.1821778116. Epub 2019 Mar 25.

6.

Two to Tango: Co-evolution of Hominid Natural Killer Cell Receptors and MHC.

Wroblewski EE, Parham P, Guethlein LA.

Front Immunol. 2019 Feb 19;10:177. doi: 10.3389/fimmu.2019.00177. eCollection 2019. Review.

7.

Casting a wider net: Immunosurveillance by nonclassical MHC molecules.

D'Souza MP, Adams E, Altman JD, Birnbaum ME, Boggiano C, Casorati G, Chien YH, Conley A, Eckle SBG, Früh K, Gondré-Lewis T, Hassan N, Huang H, Jayashankar L, Kasmar AG, Kunwar N, Lavelle J, Lewinsohn DM, Moody B, Picker L, Ramachandra L, Shastri N, Parham P, McMichael AJ, Yewdell JW.

PLoS Pathog. 2019 Feb 21;15(2):e1007567. doi: 10.1371/journal.ppat.1007567. eCollection 2019 Feb. Review.

8.

Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates.

Leaton LA, Shortt J, Kichula KM, Tao S, Nemat-Gorgani N, Mentzer AJ, Oppenheimer SJ, Deng Z, Hollenbach JA, Gignoux CR, Guethlein LA, Parham P, Carrington M, Norman PJ.

Front Immunol. 2019 Jan 28;10:24. doi: 10.3389/fimmu.2019.00024. eCollection 2019.

9.

Correction: High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia.

Huhn O, Chazara O, Ivarsson MA, Retière C, Venkatesan TC, Norman PJ, Hilton HG, Jayaraman J, Traherne JA, Trowsdale J, Ito M, Kling C, Parham P, Ghadially H, Moffett A, Sharkey AM, Colucci F.

J Immunol. 2019 Mar 15;202(6):1904. doi: 10.4049/jimmunol.1900036. Epub 2019 Feb 6. No abstract available.

PMID:
30728211
10.

Donor Killer Cell Immunoglobulin-Like Receptor Genotype Does Not Improve Graft-versus-Leukemia Responses in Chronic Lymphocytic Leukemia after Unrelated Donor Transplant: A Center for International Blood and Marrow Transplant Research Analysis.

Bachanova V, Weisdorf DJ, Wang T, Marsh SGE, Cereb N, Haagenson MD, Spellman SR, Lee SJ, Guethlein LA, Parham P, Miller JS, Cooley SA.

Biol Blood Marrow Transplant. 2019 May;25(5):949-954. doi: 10.1016/j.bbmt.2018.12.763. Epub 2018 Dec 27.

PMID:
30594542
11.

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.

Illing PT, Pymm P, Croft NP, Hilton HG, Jojic V, Han AS, Mendoza JL, Mifsud NA, Dudek NL, McCluskey J, Parham P, Rossjohn J, Vivian JP, Purcell AW.

Nat Commun. 2018 Nov 8;9(1):4693. doi: 10.1038/s41467-018-07109-w.

12.

Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop.

Misra MK, Augusto DG, Martin GM, Nemat-Gorgani N, Sauter J, Hofmann JA, Traherne JA, González-Quezada B, Gorodezky C, Bultitude WP, Marin W, Vierra-Green C, Anderson KM, Balas A, Caro-Oleas JL, Cisneros E, Colucci F, Dandekar R, Elfishawi SM, Fernández-Viña MA, Fouda M, González-Fernández R, Große A, Herrero-Mata MJ, Hollenbach SQ, Marsh SGE, Mentzer A, Middleton D, Moffett A, Moreno-Hidalgo MA, Mossallam GI, Nakimuli A, Oksenberg JR, Oppenheimer SJ, Parham P, Petzl-Erler ML, Planelles D, Sánchez-García F, Sánchez-Gordo F, Schmidt AH, Trowsdale J, Vargas LB, Vicario JL, Vilches C, Norman PJ, Hollenbach JA.

Hum Immunol. 2018 Dec;79(12):825-833. doi: 10.1016/j.humimm.2018.10.003. Epub 2018 Oct 12.

PMID:
30321631
13.

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia.

Huhn O, Chazara O, Ivarsson MA, Retière C, Venkatesan TC, Norman PJ, Hilton HG, Jayaraman J, Traherne JA, Trowsdale J, Ito M, Kling C, Parham P, Ghadially H, Moffett A, Sharkey AM, Colucci F.

J Immunol. 2018 Nov 1;201(9):2593-2601. doi: 10.4049/jimmunol.1800860. Epub 2018 Sep 24. Erratum in: J Immunol. 2019 Mar 15;202(6):1904.

14.

KIR Donor Selection: Feasibility in Identifying better Donors.

Weisdorf D, Cooley S, Wang T, Trachtenberg E, Haagenson MD, Vierra-Green C, Spellman S, Spahn A, Vogel J, Kobusingye H, Fehninger T, Woolfrey A, Devine S, Ross M, Waller EK, Sobecks R, Parham P, Guethlein LA, Marsh SGE, Miller J; participating center writing committee.

Biol Blood Marrow Transplant. 2019 Jan;25(1):e28-e32. doi: 10.1016/j.bbmt.2018.08.022. Epub 2018 Aug 24.

PMID:
30149149
15.

Nomenclature for the KIR of non-human species.

Robinson J, Guethlein LA, Maccari G, Blokhuis J, Bimber BN, de Groot NG, Sanderson ND, Abi-Rached L, Walter L, Bontrop RE, Hammond JA, Marsh SGE, Parham P.

Immunogenetics. 2018 Sep;70(9):571-583. doi: 10.1007/s00251-018-1064-4. Epub 2018 Jun 4.

16.

Molecular definition of the transplantation antigens.

Parham P.

FEBS J. 2018 Aug;285(15):2728-2745. doi: 10.1111/febs.14474. Epub 2018 May 1. Review.

17.

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa.

Nemat-Gorgani N, Hilton HG, Henn BM, Lin M, Gignoux CR, Myrick JW, Werely CJ, Granka JM, Möller M, Hoal EG, Yawata M, Yawata N, Boelen L, Asquith B, Parham P, Norman PJ.

J Immunol. 2018 Apr 15;200(8):2640-2655. doi: 10.4049/jimmunol.1701780. Epub 2018 Mar 16.

18.

Genetics of Natural Killer Cells in Human Health, Disease, and Survival.

Parham P, Guethlein LA.

Annu Rev Immunol. 2018 Apr 26;36:519-548. doi: 10.1146/annurev-immunol-042617-053149. Epub 2018 Feb 2. Review.

PMID:
29394121
19.

Strategies to activate NK cells to prevent relapse and induce remission following hematopoietic stem cell transplantation.

Cooley S, Parham P, Miller JS.

Blood. 2018 Mar 8;131(10):1053-1062. doi: 10.1182/blood-2017-08-752170. Epub 2018 Jan 22. Review.

20.

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.

Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK, Lifson JD, Fellay J, Deeks SG, Martin JN, Goedert JJ, Wolinsky SM, Michael NL, Kirk GD, Buchbinder S, Haas D, Ndung'u T, Goulder P, Parham P, Walker BD, Carlson JM, Carrington M.

Science. 2018 Jan 5;359(6371):86-90. doi: 10.1126/science.aam8825. Epub 2018 Jan 4. Erratum in: Science. 2019 Aug 2;365(6452):.

21.

Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage.

Pugh JL, Nemat-Gorgani N, Norman PJ, Guethlein LA, Parham P.

J Immunol. 2018 Feb 1;200(3):1146-1158. doi: 10.4049/jimmunol.1700542. Epub 2017 Dec 20.

22.

Missing or altered self: human NK cell receptors that recognize HLA-C.

Hilton HG, Parham P.

Immunogenetics. 2017 Aug;69(8-9):567-579. doi: 10.1007/s00251-017-1001-y. Epub 2017 Jul 10. Review.

23.

KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans.

Blokhuis JH, Hilton HG, Guethlein LA, Norman PJ, Nemat-Gorgani N, Nakimuli A, Chazara O, Moffett A, Parham P.

Immun Inflamm Dis. 2017 Dec;5(4):461-468. doi: 10.1002/iid3.178. Epub 2017 Jul 6.

24.

Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles.

Robinson J, Guethlein LA, Cereb N, Yang SY, Norman PJ, Marsh SGE, Parham P.

PLoS Genet. 2017 Jun 26;13(6):e1006862. doi: 10.1371/journal.pgen.1006862. eCollection 2017 Jun.

25.

The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands.

Hilton HG, McMurtrey CP, Han AS, Djaoud Z, Guethlein LA, Blokhuis JH, Pugh JL, Goyos A, Horowitz A, Buchli R, Jackson KW, Bardet W, Bushnell DA, Robinson PJ, Mendoza JL, Birnbaum ME, Nielsen M, Garcia KC, Hildebrand WH, Parham P.

Cell Rep. 2017 May 16;19(7):1394-1405. doi: 10.1016/j.celrep.2017.04.059.

26.

Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and γδ T cells.

Djaoud Z, Guethlein LA, Horowitz A, Azzi T, Nemat-Gorgani N, Olive D, Nadal D, Norman PJ, Münz C, Parham P.

J Exp Med. 2017 Jun 5;214(6):1827-1841. doi: 10.1084/jem.20161017. Epub 2017 May 3.

27.

A large-scale stochastic spatiotemporal model for Aedes albopictus-borne chikungunya epidemiology.

Erguler K, Chandra NL, Proestos Y, Lelieveld J, Christophides GK, Parham PE.

PLoS One. 2017 Mar 31;12(3):e0174293. doi: 10.1371/journal.pone.0174293. eCollection 2017.

28.

Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.

Norman PJ, Norberg SJ, Guethlein LA, Nemat-Gorgani N, Royce T, Wroblewski EE, Dunn T, Mann T, Alicata C, Hollenbach JA, Chang W, Shults Won M, Gunderson KL, Abi-Rached L, Ronaghi M, Parham P.

Genome Res. 2017 May;27(5):813-823. doi: 10.1101/gr.213538.116. Epub 2017 Mar 30.

29.

Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B.

Wroblewski EE, Guethlein LA, Norman PJ, Li Y, Shaw CM, Han AS, Ndjango JN, Ahuka-Mundeke S, Georgiev AV, Peeters M, Hahn BH, Parham P.

J Immunol. 2017 May 1;198(9):3480-3493. doi: 10.4049/jimmunol.1601955. Epub 2017 Mar 27.

30.

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes.

Guethlein LA, Norman PJ, Heijmans CM, de Groot NG, Hilton HG, Babrzadeh F, Abi-Rached L, Bontrop RE, Parham P.

J Immunol. 2017 Apr 15;198(8):3157-3169. doi: 10.4049/jimmunol.1602163. Epub 2017 Mar 6.

31.

Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C.

Hilton HG, Blokhuis JH, Guethlein LA, Norman PJ, Parham P.

J Immunol. 2017 Mar 1;198(5):1961-1973. doi: 10.4049/jimmunol.1601835. Epub 2017 Jan 25.

32.

Class I HLA haplotypes form two schools that educate NK cells in different ways.

Horowitz A, Djaoud Z, Nemat-Gorgani N, Blokhuis J, Hilton HG, Béziat V, Malmberg KJ, Norman PJ, Guethlein LA, Parham P.

Sci Immunol. 2016 Sep;1(3). pii: eaag1672. doi: 10.1126/sciimmunol.aag1672. Epub 2016 Sep 9.

33.

How the codfish changed its immune system.

Parham P.

Nat Genet. 2016 Sep 28;48(10):1103-4. doi: 10.1038/ng.3684.

PMID:
27681288
34.

HLA class I variation in Iranian Lur and Kurd populations: high haplotype and allotype diversity with an abundance of KIR ligands.

Ashouri E, Norman PJ, Guethlein LA, Han AS, Nemat-Gorgani N, Norberg SJ, Ghaderi A, Parham P.

HLA. 2016 Sep;88(3):87-99. doi: 10.1111/tan.12852. Epub 2016 Aug 24.

35.

Clathrin light chains' role in selective endocytosis influences antibody isotype switching.

Wu S, Majeed SR, Evans TM, Camus MD, Wong NM, Schollmeier Y, Park M, Muppidi JR, Reboldi A, Parham P, Cyster JG, Brodsky FM.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9816-21. doi: 10.1073/pnas.1611189113. Epub 2016 Aug 18.

36.

Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution.

Penman BS, Moffett A, Chazara O, Gupta S, Parham P.

Immunogenetics. 2016 Nov;68(10):755-764. Epub 2016 Aug 12.

37.

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.

Norman PJ, Hollenbach JA, Nemat-Gorgani N, Marin WM, Norberg SJ, Ashouri E, Jayaraman J, Wroblewski EE, Trowsdale J, Rajalingam R, Oksenberg JR, Chiaroni J, Guethlein LA, Traherne JA, Ronaghi M, Parham P.

Am J Hum Genet. 2016 Aug 4;99(2):375-91. doi: 10.1016/j.ajhg.2016.06.023.

38.

Correction: Structural Perturbations to Population Skeletons: Transient Dynamics, Coexistence of Attractors and the Rarity of Chaos.

Singh BK, Parham PE, Hu CK.

PLoS One. 2016 Jun 10;11(6):e0157617. doi: 10.1371/journal.pone.0157617. eCollection 2016.

39.

Donor KIR B Genotype Improves Progression-Free Survival of Non-Hodgkin Lymphoma Patients Receiving Unrelated Donor Transplantation.

Bachanova V, Weisdorf DJ, Wang T, Marsh SGE, Trachtenberg E, Haagenson MD, Spellman SR, Ladner M, Guethlein LA, Parham P, Miller JS, Cooley SA.

Biol Blood Marrow Transplant. 2016 Sep;22(9):1602-1607. doi: 10.1016/j.bbmt.2016.05.016. Epub 2016 May 21.

40.

Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1.

Alicata C, Pende D, Meazza R, Canevali P, Loiacono F, Bertaina A, Locatelli F, Nemat-Gorgani N, Guethlein LA, Parham P, Moretta L, Moretta A, Bottino C, Norman PJ, Falco M.

Eur J Immunol. 2016 Jun;46(6):1511-7. doi: 10.1002/eji.201546236.

41.

Description of the novel KIR2DL4*035 allele identified using high-throughput sequencing.

Alicata C, Bottino C, Guethlein LA, Parham P, Norman PJ.

HLA. 2016 Mar;87(3):191-3. doi: 10.1111/tan.12761. Epub 2016 Feb 24.

PMID:
26917249
42.

Large-Scale Modelling of the Environmentally-Driven Population Dynamics of Temperate Aedes albopictus (Skuse).

Erguler K, Smith-Unna SE, Waldock J, Proestos Y, Christophides GK, Lelieveld J, Parham PE.

PLoS One. 2016 Feb 12;11(2):e0149282. doi: 10.1371/journal.pone.0149282. eCollection 2016.

43.

Conducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches.

Hughes D, Charles J, Dawoud D, Edwards RT, Holmes E, Jones C, Parham P, Plumpton C, Ridyard C, Lloyd-Williams H, Wood E, Yeo ST.

Pharmacoeconomics. 2016 May;34(5):447-61. doi: 10.1007/s40273-015-0371-y. Review.

PMID:
26753558
44.

Complex MHC Class I Gene Transcription Profiles and Their Functional Impact in Orangutans.

de Groot NG, Heijmans CM, van der Wiel MK, Blokhuis JH, Mulder A, Guethlein LA, Doxiadis GG, Claas FH, Parham P, Bontrop RE.

J Immunol. 2016 Jan 15;196(2):750-8. doi: 10.4049/jimmunol.1500820. Epub 2015 Dec 18.

45.

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation.

Horowitz A, Guethlein LA, Nemat-Gorgani N, Norman PJ, Cooley S, Miller JS, Parham P.

J Immunol. 2015 Nov 1;195(9):4524-36. doi: 10.4049/jimmunol.1401990. Epub 2015 Sep 28.

46.

Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing.

Mack SJ, Milius RP, Gifford BD, Sauter J, Hofmann J, Osoegawa K, Robinson J, Groeneweg M, Turenchalk GS, Adai A, Holcomb C, Rozemuller EH, Penning MT, Heuer ML, Wang C, Salit ML, Schmidt AH, Parham PR, Müller C, Hague T, Fischer G, Fernandez-Viňa M, Hollenbach JA, Norman PJ, Maiers M.

Hum Immunol. 2015 Dec;76(12):954-62. doi: 10.1016/j.humimm.2015.09.011. Epub 2015 Sep 25.

47.

Larval and adult environmental temperatures influence the adult reproductive traits of Anopheles gambiae s.s.

Christiansen-Jucht CD, Parham PE, Saddler A, Koella JC, Basáñez MG.

Parasit Vectors. 2015 Sep 17;8:456. doi: 10.1186/s13071-015-1053-5.

48.

A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I Molecule.

Goyos A, Guethlein LA, Horowitz A, Hilton HG, Gleimer M, Brodsky FM, Parham P.

J Immunol. 2015 Oct 15;195(8):3725-36. doi: 10.4049/jimmunol.1500397. Epub 2015 Sep 14.

49.

Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes.

Hilton HG, Guethlein LA, Goyos A, Nemat-Gorgani N, Bushnell DA, Norman PJ, Parham P.

J Immunol. 2015 Oct 1;195(7):3160-70. doi: 10.4049/jimmunol.1501358. Epub 2015 Aug 26.

50.

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

Hilton HG, Norman PJ, Nemat-Gorgani N, Goyos A, Hollenbach JA, Henn BM, Gignoux CR, Guethlein LA, Parham P.

PLoS Genet. 2015 Aug 20;11(8):e1005439. doi: 10.1371/journal.pgen.1005439. eCollection 2015 Aug.

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