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Field Validation of Limiting-Antigen Avidity Enzyme Immunoassay to Estimate HIV-1 Incidence in Cross-Sectional Survey in Swaziland.

Duong YT, Dobbs T, Mavengere Y, Manjengwa J, Rottinghaus E, Saito S, Bock N, Philip N, Justman J, Bicego G, Nkengasong JN, Parekh BS.

AIDS Res Hum Retroviruses. 2019 Oct;35(10):896-905. doi: 10.1089/AID.2018.0284. Epub 2019 Aug 15.


Tracking with recency assays to control the epidemic: real-time HIV surveillance and public health response.

Kim AA, Behel S, Northbrook S, Parekh BS.

AIDS. 2019 Jul 15;33(9):1527-1529. doi: 10.1097/QAD.0000000000002239. No abstract available.


Diagnosis of Human Immunodeficiency Virus Infection.

Parekh BS, Ou CY, Fonjungo PN, Kalou MB, Rottinghaus E, Puren A, Alexander H, Hurlston Cox M, Nkengasong JN.

Clin Microbiol Rev. 2018 Nov 28;32(1). pii: e00064-18. doi: 10.1128/CMR.00064-18. Print 2019 Jan. Review.


Development of a Multiplex Assay for Concurrent Diagnoses and Detection of HIV-1, HIV-2, and Recent HIV-1 Infection in a Single Test.

Yufenyuy EL, Parekh BS.

AIDS Res Hum Retroviruses. 2018 Dec;34(12):1017-1027. doi: 10.1089/AID.2017.0279. Epub 2018 Sep 22.


Shifting the HIV Paradigm from Care to Cure: Proceedings from the Caribbean Expert Summit in Barbados, August 2017.

Landis RC, Abayomi EA, Bain BC, Greene E, Janossy G, Joseph P, Kerrigan D, McCoy JP, Nunez C, O'Gorman M, Pastoors A, Parekh BS, Quimby KR, Quinn TC, Robertson KR, Thomas R, van Gorp E, Vermund SH, Wilson V.

AIDS Res Hum Retroviruses. 2018 Jul;34(7):561-569. doi: 10.1089/AID.2017.0310. Epub 2018 Jun 5.


Correlating charge heterogeneity data generated by agarose gel isoelectric focusing and ion exchange chromatography methods.

Parekh BS, Srivastava A, Sundaram S, Ching-Heish M, Goldstein J, Barry M, Zhou Q.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 15;1073:1-9. doi: 10.1016/j.jchromb.2017.11.043. Epub 2017 Dec 9.


Returning HIV-1 viral load results to participant-selected health facilities in national Population-based HIV Impact Assessment (PHIA) household surveys in three sub-Saharan African Countries, 2015 to 2016.

Saito S, Duong YT, Metz M, Lee K, Patel H, Sleeman K, Manjengwa J, Ogollah FM, Kasongo W, Mitchell R, Mugurungi O, Chimbwandira F, Moyo C, Maliwa V, Mtengo H, Nkumbula T, Ndongmo CB, Vere NS, Chipungu G, Parekh BS, Justman J, Voetsch AC.

J Int AIDS Soc. 2017 Nov;20 Suppl 7. doi: 10.1002/jia2.25004.


Modulation of IgG1 immunoeffector function by glycoengineering of the GDP-fucose biosynthesis pathway.

Kelly RM, Kowle RL, Lian Z, Strifler BA, Witcher DR, Parekh BS, Wang T, Frye CC.

Biotechnol Bioeng. 2018 Mar;115(3):705-718. doi: 10.1002/bit.26496. Epub 2017 Dec 1.


Short Communication: Heightened HIV Antibody Responses in Postpartum Women as Exemplified by Recent Infection Assays: Implications for Incidence Estimates.

Hargrove JW, van Schalkwyk C, Humphrey JH, Mutasa K, Ntozini R, Owen SM, Masciotra S, Parekh BS, Duong YT, Dobbs T, Kilmarx PH, Gonese E.

AIDS Res Hum Retroviruses. 2017 Sep;33(9):902-904. doi: 10.1089/AID.2016.0319. Epub 2017 May 24.


Estimating False-Recent Classification for the Limiting-Antigen Avidity EIA and BED-Capture Enzyme Immunoassay in Vietnam: Implications for HIV-1 Incidence Estimates.

Shah NS, Duong YT, Le LV, Tuan NA, Parekh BS, Ha HTT, Pham QD, Cuc CTT, Dobbs T, Tram TH, Lien TTX, Wagar N, Yang C, Martin A, Wolfe M, Hien NT, Kim AA.

AIDS Res Hum Retroviruses. 2017 Jun;33(6):546-554. doi: 10.1089/AID.2016.0203. Epub 2017 Mar 13.


Swaziland HIV Incidence Measurement Survey (SHIMS): a prospective national cohort study.

Justman J, Reed JB, Bicego G, Donnell D, Li K, Bock N, Koler A, Philip NM, Mlambo CK, Parekh BS, Duong YT, Ellenberger DL, El-Sadr WM, Nkambule R.

Lancet HIV. 2017 Feb;4(2):e83-e92. doi: 10.1016/S2352-3018(16)30190-4. Epub 2016 Nov 16.


HIV testing and human rights: the right to the right test.

Nkengasong JN, Parekh BS, Hader SL.

Lancet HIV. 2016 Oct;3(10):e457-8. doi: 10.1016/S2352-3018(16)30160-6. No abstract available.


Identifying Risk Factors for Recent HIV Infection in Kenya Using a Recent Infection Testing Algorithm: Results from a Nationally Representative Population-Based Survey.

Kim AA, Parekh BS, Umuro M, Galgalo T, Bunnell R, Makokha E, Dobbs T, Murithi P, Muraguri N, De Cock KM, Mermin J; 2007 KAIS study group.

PLoS One. 2016 May 19;11(5):e0155498. doi: 10.1371/journal.pone.0155498. eCollection 2016.


Mean Recency Period for Estimation of HIV-1 Incidence with the BED-Capture EIA and Bio-Rad Avidity in Persons Diagnosed in the United States with Subtype B.

Hanson DL, Song R, Masciotra S, Hernandez A, Dobbs TL, Parekh BS, Owen SM, Green TA.

PLoS One. 2016 Apr 11;11(4):e0152327. doi: 10.1371/journal.pone.0152327. eCollection 2016.


Access and Quality of HIV-Related Point-of-Care Diagnostic Testing in Global Health Programs.

Fonjungo PN, Boeras DI, Zeh C, Alexander H, Parekh BS, Nkengasong JN.

Clin Infect Dis. 2016 Feb 1;62(3):369-374. doi: 10.1093/cid/civ866. Epub 2015 Sep 30. Review.


Recalibration of the limiting antigen avidity EIA to determine mean duration of recent infection in divergent HIV-1 subtypes.

Duong YT, Kassanjee R, Welte A, Morgan M, De A, Dobbs T, Rottinghaus E, Nkengasong J, Curlin ME, Kittinunvorakoon C, Raengsakulrach B, Martin M, Choopanya K, Vanichseni S, Jiang Y, Qiu M, Yu H, Hao Y, Shah N, Le LV, Kim AA, Nguyen TA, Ampofo W, Parekh BS.

PLoS One. 2015 Feb 24;10(2):e0114947. doi: 10.1371/journal.pone.0114947. eCollection 2015.


Poor performance of the determine HIV-1/2 Ag/Ab combo fourth-generation rapid test for detection of acute infections in a National Household Survey in Swaziland.

Duong YT, Mavengere Y, Patel H, Moore C, Manjengwa J, Sibandze D, Rasberry C, Mlambo C, Li Z, Emel L, Bock N, Moore J, Nkambule R, Justman J, Reed J, Bicego G, Ellenberger DL, Nkengasong JN, Parekh BS.

J Clin Microbiol. 2014 Oct;52(10):3743-8. doi: 10.1128/JCM.01989-14. Epub 2014 Aug 13.


Development of a novel rapid HIV test for simultaneous detection of recent or long-term HIV type 1 infection using a single testing device.

Granade TC, Nguyen S, Kuehl DS, Parekh BS.

AIDS Res Hum Retroviruses. 2013 Jan;29(1):61-7. doi: 10.1089/aid.2012.0121.


Development and validation of an antibody-dependent cell-mediated cytotoxicity-reporter gene assay.

Parekh BS, Berger E, Sibley S, Cahya S, Xiao L, LaCerte MA, Vaillancourt P, Wooden S, Gately D.

MAbs. 2012 May-Jun;4(3):310-8. doi: 10.4161/mabs.19873. Epub 2012 Apr 26.


Detection of recent HIV-1 infection using a new limiting-antigen avidity assay: potential for HIV-1 incidence estimates and avidity maturation studies.

Duong YT, Qiu M, De AK, Jackson K, Dobbs T, Kim AA, Nkengasong JN, Parekh BS.

PLoS One. 2012;7(3):e33328. doi: 10.1371/journal.pone.0033328. Epub 2012 Mar 27.


HIV testing in developing countries: what is required?

Alemnji G, Nkengasong JN, Parekh BS.

Indian J Med Res. 2011 Dec;134(6):779-86. doi: 10.4103/0971-5916.92625. Review.


A comprehensive evaluation of the proficiency testing program for the HIV-1 BED incidence assay.

Dobbs T, Liu X, Anderson R, Nkengasong J, Parekh BS.

J Clin Microbiol. 2011 Oct;49(10):3470-3. doi: 10.1128/JCM.01122-11. Epub 2011 Aug 10.


Determination of mean recency period for estimation of HIV type 1 Incidence with the BED-capture EIA in persons infected with diverse subtypes.

Parekh BS, Hanson DL, Hargrove J, Branson B, Green T, Dobbs T, Constantine N, Overbaugh J, McDougal JS.

AIDS Res Hum Retroviruses. 2011 Mar;27(3):265-73. doi: 10.1089/aid.2010.0159. Epub 2010 Oct 18.


Scaling up HIV rapid testing in developing countries: comprehensive approach for implementing quality assurance.

Parekh BS, Kalou MB, Alemnji G, Ou CY, Gershy-Damet GM, Nkengasong JN.

Am J Clin Pathol. 2010 Oct;134(4):573-84. doi: 10.1309/AJCPTDIMFR00IKYX.


Evaluating the BED capture enzyme immunoassay to estimate HIV incidence among adults in three countries in sub-Saharan Africa.

Kim AA, McDougal JS, Hargrove J, Rehle T, Pillay-Van Wyk V, Puren A, Ekra A, Borget-Alloue MY, Adje-Toure C, Abdullahi AS, Odawo L, Marum L, Parekh BS.

AIDS Res Hum Retroviruses. 2010 Oct;26(10):1051-61. doi: 10.1089/aid.2009.0218. Epub 2010 Sep 19.


Transmitted drug resistance and type of infection in newly diagnosed HIV-1 individuals in Honduras.

Murillo W, Paz-Bailey G, Morales S, Monterroso E, Paredes M, Dobbs T, Parekh BS, Albert J, Rivera IL.

J Clin Virol. 2010 Dec;49(4):239-44. doi: 10.1016/j.jcv.2010.03.013. Epub 2010 Apr 22.


Development of two avidity-based assays to detect recent HIV type 1 seroconversion using a multisubtype gp41 recombinant protein.

Wei X, Liu X, Dobbs T, Kuehl D, Nkengasong JN, Hu DJ, Parekh BS.

AIDS Res Hum Retroviruses. 2010 Jan;26(1):61-71. doi: 10.1089/aid.2009.0133.


Dried tube specimens: a simple and cost-effective method for preparation of HIV proficiency testing panels and quality control materials for use in resource-limited settings.

Parekh BS, Anyanwu J, Patel H, Downer M, Kalou M, Gichimu C, Keipkerich BS, Clement N, Omondi M, Mayer O, Ou CY, Nkengasong JN.

J Virol Methods. 2010 Feb;163(2):295-300. doi: 10.1016/j.jviromet.2009.10.013. Epub 2009 Oct 28.


Current HIV-2 diagnostic strategy overestimates HIV-2 prevalence in China.

Qiu M, Liu X, Jiang Y, Nkengasong JN, Xing W, Pei L, Parekh BS.

J Med Virol. 2009 May;81(5):790-7. doi: 10.1002/jmv.21441.


Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.

Johnson TA, Elbi C, Parekh BS, Hager GL, John S.

Mol Biol Cell. 2008 Aug;19(8):3308-22. doi: 10.1091/mbc.E08-02-0123. Epub 2008 May 28.


Alternative algorithms for human immunodeficiency virus infection diagnosis using tests that are licensed in the United States.

Owen SM, Yang C, Spira T, Ou CY, Pau CP, Parekh BS, Candal D, Kuehl D, Kennedy MS, Rudolph D, Luo W, Delatorre N, Masciotra S, Kalish ML, Cowart F, Barnett T, Lal R, McDougal JS.

J Clin Microbiol. 2008 May;46(5):1588-95. doi: 10.1128/JCM.02196-07. Epub 2008 Mar 5.


Improved HIV-1 incidence estimates using the BED capture enzyme immunoassay.

Hargrove JW, Humphrey JH, Mutasa K, Parekh BS, McDougal JS, Ntozini R, Chidawanyika H, Moulton LH, Ward B, Nathoo K, Iliff PJ, Kopp E.

AIDS. 2008 Feb 19;22(4):511-8. doi: 10.1097/QAD.0b013e3282f2a960.


Temporal trends in the incidence of HIV infection in antenatal clinic attendees in Addis Ababa, Ethiopia, 1995-2003.

Wolday D, Meles H, Hailu E, Messele T, Mengistu Y, Fekadu M, Parekh BS, Wuhib T.

J Intern Med. 2007 Feb;261(2):132-7.


Comparison of HIV type 1 incidence observed during longitudinal follow-up with incidence estimated by cross-sectional analysis using the BED capture enzyme immunoassay.

McDougal JS, Parekh BS, Peterson ML, Branson BM, Dobbs T, Ackers M, Gurwith M.

AIDS Res Hum Retroviruses. 2006 Oct;22(10):945-52.


HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription.

Qiu Y, Zhao Y, Becker M, John S, Parekh BS, Huang S, Hendarwanto A, Martinez ED, Chen Y, Lu H, Adkins NL, Stavreva DA, Wiench M, Georgel PT, Schiltz RL, Hager GL.

Mol Cell. 2006 Jun 9;22(5):669-79.


Modification of rapid human immunodeficiency virus (HIV) antibody assay protocols for detecting recent HIV seroconversion.

Soroka SD, Granade TC, Candal D, Parekh BS.

Clin Diagn Lab Immunol. 2005 Aug;12(8):918-21.


Trends of HIV-1 seroincidence among HIV-1 sentinel surveillance groups in Cambodia, 1999-2002.

Saphonn V, Parekh BS, Dobbs T, Mean C, Bun LH, Ly SP, Heng S, Detels R.

J Acquir Immune Defic Syndr. 2005 Aug 15;39(5):587-92.


Evaluation of rapid prenatal human immunodeficiency virus testing in rural cameroon.

Granade TC, Parekh BS, Tih PM, Welty T, Welty E, Bulterys M, Ndikintum G, Nkuoh G, Tancho S.

Clin Diagn Lab Immunol. 2005 Jul;12(7):855-60.


Surveillance for HIV-1 incidence using tests for recent infection in resource-constrained countries.

McDougal JS, Pilcher CD, Parekh BS, Gershy-Damet G, Branson BM, Marsh K, Wiktor SZ.

AIDS. 2005 May;19 Suppl 2:S25-30. Review.


Application of laboratory methods for estimation of HIV-1 incidence.

Parekh BS, McDougal JS.

Indian J Med Res. 2005 Apr;121(4):510-8. Review.


Unsafe injections and transmission of HIV-1 in sub-Saharan Africa.

Bulterys M, Chao A, Dushimimana A, Parekh BS.

Lancet. 2004 May 15;363(9421):1650. No abstract available.


Performance of the OraQuick and Hema-Strip rapid HIV antibody detection assays by non-laboratorians.

Granade TC, Parekh BS, Phillips SK, McDougal JS.

J Clin Virol. 2004 Jul;30(3):229-32.


HIV type 1 incidence estimates by detection of recent infection from a cross-sectional sampling of injection drug users in Bangkok: use of the IgG capture BED enzyme immunoassay.

Hu DJ, Vanichseni S, Mock PA, Young NL, Dobbs T, Byers RH Jr, Choopanya K, van Griensven F, Kitayaporn D, McDougal JS, Tappero JW, Mastro TD, Parekh BS.

AIDS Res Hum Retroviruses. 2003 Sep;19(9):727-30.


Detecting recent human immunodeficiency virus type 1 infection: why and how?

Dobbs T, Parekh BS.

MLO Med Lab Obs. 2003 May;35(5):12-4, 16, 19-20 passim; quiz 24-5. No abstract available.


Inhibition of human papilloma virus E2 DNA binding protein by covalently linked polyamides.

Schaal TD, Mallet WG, McMinn DL, Nguyen NV, Sopko MM, John S, Parekh BS.

Nucleic Acids Res. 2003 Feb 15;31(4):1282-91.


Chronic immune stimulation accelerates SIV-induced disease progression.

Villinger F, Rowe T, Parekh BS, Green TA, Mayne AE, Grimm B, McClure HM, Lackner AA, Dailey PJ, Ansari AA, Folks TM.

J Med Primatol. 2001 Oct;30(5):254-9.


Quantitative detection of increasing HIV type 1 antibodies after seroconversion: a simple assay for detecting recent HIV infection and estimating incidence.

Parekh BS, Kennedy MS, Dobbs T, Pau CP, Byers R, Green T, Hu DJ, Vanichseni S, Young NL, Choopanya K, Mastro TD, McDougal JS.

AIDS Res Hum Retroviruses. 2002 Mar 1;18(4):295-307.


HIV-specific IgG in cervicovaginal secretions of exposed HIV-uninfected female sexual partners of HIV-infected men.

Buchacz K, Parekh BS, Padian NS, van der Straten A, Phillips S, Jonte J, Holmberg SD.

AIDS Res Hum Retroviruses. 2001 Dec 10;17(18):1689-93.


Efficacy of a less-sensitive enzyme immunoassay (3A11-LS) for early diagnosis of human immunodeficiency virus Type 1 infection in infants.

Candal D, Bulterys M, Abrams EJ, Steketee RW, Parekh BS.

Clin Diagn Lab Immunol. 2001 Nov;8(6):1282-5.

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