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Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant.

Beltran-Pavez C, Ferreira CB, Merino-Mansilla A, Fabra-Garcia A, Casadella M, Noguera-Julian M, Paredes R, Olvera A, Haro I, Brander C, Garcia F, Gatell JM, Yuste E, Sanchez-Merino V.

PLoS One. 2018 Dec 19;13(12):e0208345. doi: 10.1371/journal.pone.0208345. eCollection 2018.


Reply to Ambrosioni et al.

Günthard HF, Calvez V, Paredes R, Pillay D, Shafer RW, Wensing AM, Jacobsen DM, Richman DD.

Clin Infect Dis. 2018 Dec 6. doi: 10.1093/cid/ciy1022. [Epub ahead of print] No abstract available.


Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers.

Rosás-Umbert M, Llano A, Bellido R, Olvera A, Ruiz-Riol M, Rocafort M, Fernández MA, Cobarsi P, Crespo M, Dorrell L, Del Romero J, Alcami J, Paredes R, Brander C, Mothe B.

J Virol. 2018 Nov 28. pii: JVI.01436-18. doi: 10.1128/JVI.01436-18. [Epub ahead of print]


The First Mating Experience Induces New Neurons in the Olfactory Bulb in Male Mice.

Velazco-Mendoza M, Camacho FJ, Paredes RG, Portillo W.

Neuroscience. 2019 Jan 1;396:166-174. doi: 10.1016/j.neuroscience.2018.11.019. Epub 2018 Nov 22.


Paced mating increases the expression of μ opioid receptors in the ventromedial hypothalamus of male rats.

Bedos M, Antaramian A, Gonzalez-Gallardo A, Paredes RG.

Behav Brain Res. 2019 Feb 1;359:401-407. doi: 10.1016/j.bbr.2018.11.027. Epub 2018 Nov 17.


Bioinformatic data processing pipelines in support of next-generation sequencing-based HIV drug resistance testing: the Winnipeg Consensus.

Ji H, Enns E, Brumme CJ, Parkin N, Howison M, Lee ER, Capina R, Marinier E, Avila-Rios S, Sandstrom P, Van Domselaar G, Harrigan R, Paredes R, Kantor R, Noguera-Julian M.

J Int AIDS Soc. 2018 Oct;21(10):e25193. doi: 10.1002/jia2.25193.


Cost-Effectiveness of rFVIIa versus pd-aPCC in the Management of Mild to Moderate Bleeds in Pediatric Patients with Hemophilia A with Inhibitors in Mexico.

Rodríguez-Zepeda MDC, González L, Bravo A, Pompa T, Silva S, Paredes R, García J, Ramos M, Wilkinson L, Lamotte M.

Value Health Reg Issues. 2018 Dec;17:164-173. doi: 10.1016/j.vhri.2018.06.007. Epub 2018 Oct 12.


Echinococcus granulosus hydatid cyst location is modified by Fasciola hepatica infection in cattle.

Stoore C, Andrade C, Hidalgo C, Corrêa F, Jiménez M, Hernandez M, Paredes R.

Parasit Vectors. 2018 Oct 10;11(1):542. doi: 10.1186/s13071-018-3128-6.


Clinically relevant thresholds for ultrasensitive HIV drug resistance testing: a multi-country nested case-control study.

Inzaule SC, Hamers RL, Noguera-Julian M, Casadellà M, Parera M, Kityo C, Steegen K, Naniche D, Clotet B, Rinke de Wit TF, Paredes R; PanAfrican Studies to Evaluate Resistance.

Lancet HIV. 2018 Nov;5(11):e638-e646. doi: 10.1016/S2352-3018(18)30177-2. Epub 2018 Sep 30.


Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection.

Guillén Y, Noguera-Julian M, Rivera J, Casadellà M, Zevin AS, Rocafort M, Parera M, Rodríguez C, Arumí M, Carrillo J, Mothe B, Estany C, Coll J, Bravo I, Herrero C, Saz J, Sirera G, Torrella A, Navarro J, Crespo M, Negredo E, Brander C, Blanco J, Calle ML, Klatt NR, Clotet B, Paredes R.

Mucosal Immunol. 2019 Jan;12(1):232-246. doi: 10.1038/s41385-018-0083-7. Epub 2018 Aug 31.


Hippocampal sclerosis induced in mice by a Taenia crassiceps metacestode factor.

Zepeda N, Copitin N, Chávez JL, García F, Jaimes-Miranda F, Rincón-Heredia R, Paredes R, Solano S, Fernández AM, Molinari JL.

J Helminthol. 2018 Aug 23:1-7. doi: 10.1017/S0022149X18000755. [Epub ahead of print]


A Summary of the Third Annual HIV Microbiome Workshop.

Williams B, Boucher C, Bushman F, Carrington-Lawrence S, Collman R, Dandekar S, Dang Q, Malaspina A, Paredes R, Wilson C, Nowak P, Klatt N, Lagenaur L, Landay A.

AIDS Res Hum Retroviruses. 2018 Oct;34(10):828-834. doi: 10.1089/AID.2018.0103. Epub 2018 Oct 9.


EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association.

Paredes R, Schneider M, Stevens A, White DJ, K Williamson AJ, Muter J, Pearson S, Kelly JR, Connors K, Wiseman DH, Chadwick JA, Löffler H, Teng HY, Lovell S, Unwin R, van de Vrugt HJ, Smith H, Kustikova O, Schambach A, P Somervaille TC, Pierce A, Whetton AD, Meyer S.

Nucleic Acids Res. 2018 Sep 19;46(16):8663. doi: 10.1093/nar/gky711. No abstract available.


Intra-articular treatment with corticosteroids increases apoptosis in human rotator cuff tears.

Ramírez JP, Bonati-Richardson F, García MP, Hidalgo C, Stoore C, Liendo R, Soza F, Landerer E, Paredes R.

Connect Tissue Res. 2018 Aug 9:1-8. doi: 10.1080/03008207.2018.1501040. [Epub ahead of print]


Human Immunodeficiency Virus Drug Resistance: 2018 Recommendations of the International Antiviral Society-USA Panel.

Günthard HF, Calvez V, Paredes R, Pillay D, Shafer RW, Wensing AM, Jacobsen DM, Richman DD.

Clin Infect Dis. 2019 Jan 7;68(2):177-187. doi: 10.1093/cid/ciy463.


Balances: a New Perspective for Microbiome Analysis.

Rivera-Pinto J, Egozcue JJ, Pawlowsky-Glahn V, Paredes R, Noguera-Julian M, Calle ML.

mSystems. 2018 Jul 17;3(4). pii: e00053-18. doi: 10.1128/mSystems.00053-18. eCollection 2018 Jul-Aug.


EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association.

Paredes R, Schneider M, Stevens A, White DJ, Williamson AJK, Muter J, Pearson S, Kelly JR, Connors K, Wiseman DH, Chadwick JA, Löffler H, Teng HY, Lovell S, Unwin R, van de Vrugt HJ, Smith H, Kustikova O, Schambach A, Somervaille TCP, Pierce A, Whetton AD, Meyer S.

Nucleic Acids Res. 2018 Sep 6;46(15):7662-7674. doi: 10.1093/nar/gky536.


Etiological Characterization of the Cutaneous Ulcer Syndrome in Papua New Guinea Using Shotgun Metagenomics.

Noguera-Julian M, González-Beiras C, Parera M, Ubals M, Kapa A, Paredes R, Mitjà O.

Clin Infect Dis. 2019 Jan 18;68(3):482-489. doi: 10.1093/cid/ciy502.


First description of Echinococcus ortleppi and cystic echinococcosis infection status in Chile.

Corrêa F, Stoore C, Horlacher P, Jiménez M, Hidalgo C, Alvarez Rojas CA, Figueiredo Barros G, Bunselmeyer Ferreira H, Hernández M, Cabrera G, Paredes R.

PLoS One. 2018 May 17;13(5):e0197620. doi: 10.1371/journal.pone.0197620. eCollection 2018.


HIV drug resistance patterns in pregnant women using next generation sequence in Mozambique.

Rupérez M, Noguera-Julian M, González R, Maculuve S, Bellido R, Vala A, Rodríguez C, Sevene E, Paredes R, Menéndez C.

PLoS One. 2018 May 9;13(5):e0196451. doi: 10.1371/journal.pone.0196451. eCollection 2018.


Dolutegravir-based maintenance monotherapy versus dual therapy with lamivudine: a planned 24 week analysis of the DOLAM randomized clinical trial.

Blanco JL, Rojas J, Paredes R, Negredo E, Mallolas J, Casadella M, Clotet B, Gatell JM, de Lazzari E, Martinez E; DOLAM Study Team .

J Antimicrob Chemother. 2018 Jul 1;73(7):1965-1971. doi: 10.1093/jac/dky093.


Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro.

Olvera A, Martinez JP, Casadellà M, Llano A, Rosás M, Mothe B, Ruiz-Riol M, Arsequell G, Valencia G, Noguera-Julian M, Paredes R, Meyerhans A, Brander C.

Front Immunol. 2018 Jan 26;8:2010. doi: 10.3389/fimmu.2017.02010. eCollection 2017.


Primary resistance to integrase strand transfer inhibitors in patients infected with diverse HIV-1 subtypes in sub-Saharan Africa.

Inzaule SC, Hamers RL, Noguera-Julian M, Casadellà M, Parera M, Rinke de Wit TF, Paredes R.

J Antimicrob Chemother. 2018 May 1;73(5):1167-1172. doi: 10.1093/jac/dky005.


Neurogenesis and sexual behavior.

Bedos M, Portillo W, Paredes RG.

Front Neuroendocrinol. 2018 Oct;51:68-79. doi: 10.1016/j.yfrne.2018.02.004. Epub 2018 Feb 10. Review.


Incorporation of new neurons in the olfactory bulb after paced mating in the female rat.

Alvarado-Martínez R, Paredes RG.

Behav Brain Res. 2018 May 2;343:95-101. doi: 10.1016/j.bbr.2018.02.006. Epub 2018 Feb 6.


Dynamics of Surfactant Clustering at Interfaces and Its Influence on the Interfacial Tension: Atomistic Simulation of a Sodium Hexadecane-Benzene Sulfonate-Tetradecane-Water System.

Paredes R, Fariñas-Sánchez AI, Medina-Rodrı Guez B, Samaniego S, Aray Y, Álvarez LJ.

Langmuir. 2018 Mar 6;34(9):3146-3157. doi: 10.1021/acs.langmuir.7b03719. Epub 2018 Feb 19.


Long-term effectiveness of recommended boosted protease inhibitor-based antiretroviral therapy in Europe.

Santos JR, Cozzi-Lepri A, Phillips A, De Wit S, Pedersen C, Reiss P, Blaxhult A, Lazzarin A, Sluzhynska M, Orkin C, Duvivier C, Bogner J, Gargalianos-Kakolyris P, Schmid P, Hassoun G, Khromova I, Beniowski M, Hadziosmanovic V, Sedlacek D, Paredes R, Lundgren JD; EuroSIDA study group.

HIV Med. 2018 May;19(5):324-338. doi: 10.1111/hiv.12581. Epub 2018 Feb 1.


Resting state brain networks in the prairie vole.

Ortiz JJ, Portillo W, Paredes RG, Young LJ, Alcauter S.

Sci Rep. 2018 Jan 19;8(1):1231. doi: 10.1038/s41598-017-17610-9.


Association between the APOE ε4 Allele and Late-Onset Alzheimer's Disease in an Ecuadorian Mestizo Population.

Montufar S, Calero C, Vinueza R, Correa P, Carrera-Gonzalez A, Villegas F, Moreta G, Paredes R.

Int J Alzheimers Dis. 2017;2017:1059678. doi: 10.1155/2017/1059678. Epub 2017 Dec 4.


Nonhuman Primate (Rhesus Macaque) Models of Severe Pressure-Targeted Hemorrhagic and Polytraumatic Hemorrhagic Shock.

Sheppard FR, Macko AR, Glaser JJ, Vernon PJ, Burdette AJ, Paredes RM, Koeller CA, Pusateri AE, Tadaki DK, Cardin S.

Shock. 2018 Feb;49(2):174-186. doi: 10.1097/SHK.0000000000000910.


The Role of HIV-1 Drug-Resistant Minority Variants in Treatment Failure.

Stella-Ascariz N, Arribas JR, Paredes R, Li JZ.

J Infect Dis. 2017 Dec 1;216(suppl_9):S847-S850. doi: 10.1093/infdis/jix430. Review.


[Tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: an unattended need].

Gómez X, Valdez N, Paredes R.

Rev Peru Med Exp Salud Publica. 2017 Apr-Jun;34(2):349-350. doi: 10.17843/rpmesp.2017.342.2690. Spanish. No abstract available.


On the electron density localization in elemental cubic ceramic and FCC transition metals by means of a localized electrons detector.

Aray Y, Paredes R, Álvarez LJ, Martiz A.

J Chem Phys. 2017 Jun 14;146(22):224504. doi: 10.1063/1.4985253.


Generation of complement molecular complex C5b-9 (C5b-9) in response to poly-traumatic hemorrhagic shock and evaluation of C5 cleavage inhibitors in non-human primates.

Paredes RM, Reyna S, Vernon P, Tadaki DK, Dallelucca JJ, Sheppard F.

Int Immunopharmacol. 2018 Jan;54:221-225. doi: 10.1016/j.intimp.2017.10.033. Epub 2017 Nov 20.


Mating and social exposure induces an opioid-dependent conditioned place preference in male but not in female prairie voles (Microtus ochrogaster).

Ulloa M, Portillo W, Díaz NF, Young LJ, Camacho FJ, Rodríguez VM, Paredes RG.

Horm Behav. 2018 Jan;97:47-55. doi: 10.1016/j.yhbeh.2017.10.015. Epub 2017 Nov 8.


Neurogenesis in the olfactory bulb induced by paced mating in the female rat is opioid dependent.

Santoyo-Zedillo M, Portillo W, Paredes RG.

PLoS One. 2017 Nov 6;12(11):e0186335. doi: 10.1371/journal.pone.0186335. eCollection 2017.


Human periodontal ligament fibroblasts synthesize C-reactive protein and Th-related cytokines in response to interleukin (IL)-6 trans-signalling.

Hernández-Caldera A, Vernal R, Paredes R, Veloso-Matta P, Astorga J, Hernández M.

Int Endod J. 2018 Jun;51(6):632-640. doi: 10.1111/iej.12872. Epub 2017 Dec 4.


The immune profile induced is crucial to determine the effects of immunocastration over gonadal function, fertility, and GnRH-I expression.

Siel D, Loaiza A, Vidal S, Caruffo M, Paredes R, Ramirez G, Lapierre L, Briceño C, Pérez O, Sáenz L.

Am J Reprod Immunol. 2018 Jan;79(1). doi: 10.1111/aji.12772. Epub 2017 Oct 19.


Interferon-γ-Inducible Protein 10 (IP-10) as a Screening Tool to Optimize Human Immunodeficiency Virus RNA Monitoring in Resource-Limited Settings.

Pastor L, Casellas A, Rupérez M, Carrillo J, Maculuve S, Jairoce C, Paredes R, Blanco J, Naniche D.

Clin Infect Dis. 2017 Oct 30;65(10):1670-1675. doi: 10.1093/cid/cix600.


Next-Generation Human Immunodeficiency Virus Sequencing for Patient Management and Drug Resistance Surveillance.

Noguera-Julian M, Edgil D, Harrigan PR, Sandstrom P, Godfrey C, Paredes R.

J Infect Dis. 2017 Dec 1;216(suppl_9):S829-S833. doi: 10.1093/infdis/jix397.


Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.

Rosás-Umbert M, Mothe B, Noguera-Julian M, Bellido R, Puertas MC, Carrillo J, Rodriguez C, Perez-Alvarez N, Cobarsí P, Gomez CE, Esteban M, Jímenez JL, García F, Blanco J, Martinez-Picado J, Paredes R, Brander C.

PLoS One. 2017 Sep 27;12(9):e0184929. doi: 10.1371/journal.pone.0184929. eCollection 2017.


Neisseria gonorrhoeae Challenge Increases Matrix Metalloproteinase-8 Expression in Fallopian Tube Explants.

Juica NE, Rodas PI, Solar P, Borda P, Vargas R, Muñoz C, Paredes R, Christodoulides M, Velasquez LA.

Front Cell Infect Microbiol. 2017 Sep 6;7:399. doi: 10.3389/fcimb.2017.00399. eCollection 2017.


Cryopreservation of human whole blood allows immunophenotyping by flow cytometry up to 30days after cell isolation.

Paredes RM, Tadaki DK, Sooter A, Gamboni F, Sheppard F.

J Immunol Methods. 2018 Jan;452:32-38. doi: 10.1016/j.jim.2017.08.013. Epub 2017 Sep 18.


Hormones and the Coolidge effect.

Ventura-Aquino E, Fernández-Guasti A, Paredes RG.

Mol Cell Endocrinol. 2018 May 15;467:42-48. doi: 10.1016/j.mce.2017.09.010. Epub 2017 Sep 12. Review.


A Summary of the Second Annual HIV Microbiome Workshop.

Williams B, Ghosh M, Boucher CAB, Bushman F, Carrington-Lawrence S, Collman RG, Dandekar S, Dang Q, Malaspina A, Paredes R, Wilson CC, Nowak P, Klatt NR, Lagenaur L, Landay AL.

AIDS Res Hum Retroviruses. 2017 Dec;33(12):1258-1264. doi: 10.1089/aid.2017.0137. Epub 2017 Oct 26.


A21 HIV-1 sub-subtype F1 outbreak among MSM in Belgium.

Vinken L, Fransen K, Pineda-Peña AC, Alexiev I, Balotta C, Debaisieux L, Devaux C, García Ribas S, Gomes P, Incardona F, Kaiser R, Ruelle J, Sayan M, Paraschiv S, Paredes R, Peeters M, Sonnerborg A, Vancutsem E, Van den Wijngaert S, Van Ranst M, Verhofstede C, Vandamme AM, Lemey P, Van Laethem K.

Virus Evol. 2017 Mar 5;3(Suppl 1). pii: vew036.020. doi: 10.1093/ve/vew036.020. eCollection 2017 Mar. No abstract available.


Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells.

Iturriaga MP, Paredes R, Arias JI, Torres CG.

Oncol Lett. 2017 Aug;14(2):2198-2206. doi: 10.3892/ol.2017.6400. Epub 2017 Jun 16.


Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation.

Paredes R, Tzou PL, van Zyl G, Barrow G, Camacho R, Carmona S, Grant PM, Gupta RK, Hamers RL, Harrigan PR, Jordan MR, Kantor R, Katzenstein DA, Kuritzkes DR, Maldarelli F, Otelea D, Wallis CL, Schapiro JM, Shafer RW.

PLoS One. 2017 Jul 28;12(7):e0181357. doi: 10.1371/journal.pone.0181357. eCollection 2017.


Richer gut microbiota with distinct metabolic profile in HIV infected Elite Controllers.

Vesterbacka J, Rivera J, Noyan K, Parera M, Neogi U, Calle M, Paredes R, Sönnerborg A, Noguera-Julian M, Nowak P.

Sci Rep. 2017 Jul 24;7(1):6269. doi: 10.1038/s41598-017-06675-1.


The association between detected drug resistance mutations and CD4+ T-cell decline in HIV-positive individuals maintained on a failing treatment regimen.

Schultze A, Paredes R, Sabin C, Phillips AN, Pillay D, Mackie N, Castagna A, Chadwick D, Falconer K, Geretti AM, Post FA, Hill T, Kirk O, Pozniak A, Nelson M, Tostevin A, Dunn D, Lundgren J, Cozzi-Lepri A.

Antivir Ther. 2018;23(2):105-116. doi: 10.3851/IMP3178.


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