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Items: 1 to 50 of 63

1.

A Diallel of the Mouse Collaborative Cross Founders Reveals Strong Strain-Specific Maternal Effects on Litter Size.

Shorter JR, Maurizio PL, Bell TA, Shaw GD, Miller DR, Gooch TJ, Spence JS, McMillan L, Valdar W, Pardo-Manuel de Villena F.

G3 (Bethesda). 2019 Mar 15. pii: g3.200847.2018. doi: 10.1534/g3.118.200847. [Epub ahead of print]

2.

Whole Genome Sequencing and Progress Towards Full Inbreeding of the Mouse Collaborative Cross Population.

Shorter JR, Najarian ML, Bell TA, Blanchard M, Ferris MT, Hock P, Kashfeen A, Kirchoff KE, Linnertz CL, Sigmon JS, Miller DR, McMillan L, Pardo-Manuel de Villena F.

G3 (Bethesda). 2019 Mar 11. pii: g3.400039.2019. doi: 10.1534/g3.119.400039. [Epub ahead of print]

3.

Genetic diversity between mouse strains allows identification of the CC027/GeniUnc strain as an orally reactive model of peanut allergy.

Orgel K, Smeekens JM, Ye P, Fotsch L, Guo R, Miller DR, Pardo-Manuel de Villena F, Burks AW, Ferris MT, Kulis MD.

J Allergy Clin Immunol. 2019 Mar;143(3):1027-1037.e7. doi: 10.1016/j.jaci.2018.10.009. Epub 2018 Oct 19.

PMID:
30342892
4.

Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice.

Maurizio PL, Ferris MT, Keele GR, Miller DR, Shaw GD, Whitmore AC, West A, Morrison CR, Noll KE, Plante KS, Cockrell AS, Threadgill DW, Pardo-Manuel de Villena F, Baric RS, Heise MT, Valdar W.

G3 (Bethesda). 2018 Feb 2;8(2):427-445. doi: 10.1534/g3.117.300438.

5.

Perinatal nutrition interacts with genetic background to alter behavior in a parent-of-origin-dependent manner in adult Collaborative Cross mice.

Schoenrock SA, Oreper D, Farrington J, McMullan RC, Ervin R, Miller DR, Pardo-Manuel de Villena F, Valdar W, Tarantino LM.

Genes Brain Behav. 2018 Sep;17(7):e12438. doi: 10.1111/gbb.12438. Epub 2017 Dec 13.

PMID:
29125223
6.

Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.

Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B.

Cell. 2017 Nov 16;171(5):1015-1028.e13. doi: 10.1016/j.cell.2017.09.016. Epub 2017 Oct 19.

7.

Sequence and Structural Diversity of Mouse Y Chromosomes.

Morgan AP, Pardo-Manuel de Villena F.

Mol Biol Evol. 2017 Dec 1;34(12):3186-3204. doi: 10.1093/molbev/msx250.

8.

High-Resolution Maps of Mouse Reference Populations.

Simecek P, Forejt J, Williams RW, Shiroishi T, Takada T, Lu L, Johnson TE, Bennett B, Deschepper CF, Scott-Boyer MP, Pardo-Manuel de Villena F, Churchill GA.

G3 (Bethesda). 2017 Oct 5;7(10):3427-3434. doi: 10.1534/g3.117.300188.

9.

Genetic architecture of atherosclerosis dissected by QTL analyses in three F2 intercrosses of apolipoprotein E-null mice on C57BL6/J, DBA/2J and 129S6/SvEvTac backgrounds.

Makhanova N, Morgan AP, Kayashima Y, Makhanov A, Hiller S, Zhilicheva S, Xu L, Pardo-Manuel de Villena F, Maeda N.

PLoS One. 2017 Aug 24;12(8):e0182882. doi: 10.1371/journal.pone.0182882. eCollection 2017.

10.

Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice.

Gralinski LE, Menachery VD, Morgan AP, Totura AL, Beall A, Kocher J, Plante J, Harrison-Shostak DC, Schäfer A, Pardo-Manuel de Villena F, Ferris MT, Baric RS.

G3 (Bethesda). 2017 Jun 7;7(6):1653-1663. doi: 10.1534/g3.117.041434.

11.

Toward Personalized Gene Therapy: Characterizing the Host Genetic Control of Lentiviral-Vector-Mediated Hepatic Gene Delivery.

Suwanmanee T, Ferris MT, Hu P, Gui T, Montgomery SA, Pardo-Manuel de Villena F, Kafri T.

Mol Ther Methods Clin Dev. 2017 Apr 5;5:83-92. doi: 10.1016/j.omtm.2017.03.009. eCollection 2017 Jun 16.

12.

Long-term exercise in mice has sex-dependent benefits on body composition and metabolism during aging.

McMullan RC, Kelly SA, Hua K, Buckley BK, Faber JE, Pardo-Manuel de Villena F, Pomp D.

Physiol Rep. 2016 Nov;4(21). pii: e13011. Epub 2016 Nov 14.

13.

Transcriptional profiles of WNV neurovirulence in a genetically diverse Collaborative Cross population.

Green R, Wilkins C, Thomas S, Sekine A, Ireton RC, Ferris MT, Hendrick DM, Voss K, Pardo-Manuel de Villena F, Baric RS, Heise MT, Gale M Jr.

Genom Data. 2016 Oct 14;10:137-140. eCollection 2016 Dec.

14.

A Mouse Model of Chronic West Nile Virus Disease.

Graham JB, Swarts JL, Wilkins C, Thomas S, Green R, Sekine A, Voss KM, Ireton RC, Mooney M, Choonoo G, Miller DR, Treuting PM, Pardo Manuel de Villena F, Ferris MT, McWeeney S, Gale M Jr, Lund JM.

PLoS Pathog. 2016 Nov 2;12(11):e1005996. doi: 10.1371/journal.ppat.1005996. eCollection 2016 Nov.

15.

Genetic structure of phenotypic robustness in the collaborative cross mouse diallel panel.

Gonzalez PN, Pavlicev M, Mitteroecker P, Pardo-Manuel de Villena F, Spritz RA, Marcucio RS, Hallgrímsson B.

J Evol Biol. 2016 Sep;29(9):1737-51. doi: 10.1111/jeb.12906. Epub 2016 Jul 8.

16.

R2d2 Drives Selfish Sweeps in the House Mouse.

Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, French JE, Gabriel SI, Gatti DM, Garland T Jr, Giagia-Athanasopoulou EB, Giménez MD, Grize SA, Gündüz İ, Holmes A, Hauffe HC, Herman JS, Holt JM, Hua K, Jolley WJ, Lindholm AK, López-Fuster MJ, Mitsainas G, da Luz Mathias M, McMillan L, Ramalhinho Mda G, Rehermann B, Rosshart SP, Searle JB, Shiao MS, Solano E, Svenson KL, Thomas-Laemont P, Threadgill DW, Ventura J, Weinstock GM, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

Mol Biol Evol. 2016 Jun;33(6):1381-95. doi: 10.1093/molbev/msw036. Epub 2016 Feb 15.

17.

The Mouse Universal Genotyping Array: From Substrains to Subspecies.

Morgan AP, Fu CP, Kao CY, Welsh CE, Didion JP, Yadgary L, Hyacinth L, Ferris MT, Bell TA, Miller DR, Giusti-Rodriguez P, Nonneman RJ, Cook KD, Whitmire JK, Gralinski LE, Keller M, Attie AD, Churchill GA, Petkov P, Sullivan PF, Brennan JR, McMillan L, Pardo-Manuel de Villena F.

G3 (Bethesda). 2015 Dec 18;6(2):263-79. doi: 10.1534/g3.115.022087.

18.

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.

Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, Valdar W, Heise MT, Pardo-Manuel de Villena F, Baric RS.

PLoS Genet. 2015 Oct 9;11(10):e1005504. doi: 10.1371/journal.pgen.1005504. eCollection 2015 Oct.

19.

Genetics of murine craniofacial morphology: diallel analysis of the eight founders of the Collaborative Cross.

Percival CJ, Liberton DK, Pardo-Manuel de Villena F, Spritz R, Marcucio R, Hallgrímsson B.

J Anat. 2016 Jan;228(1):96-112. doi: 10.1111/joa.12382. Epub 2015 Oct 1.

20.

Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.

Crowley JJ, Zhabotynsky V, Sun W, Huang S, Pakatci IK, Kim Y, Wang JR, Morgan AP, Calaway JD, Aylor DL, Yun Z, Bell TA, Buus RJ, Calaway ME, Didion JP, Gooch TJ, Hansen SD, Robinson NN, Shaw GD, Spence JS, Quackenbush CR, Barrick CJ, Nonneman RJ, Kim K, Xenakis J, Xie Y, Valdar W, Lenarcic AB, Wang W, Welsh CE, Fu CP, Zhang Z, Holt J, Guo Z, Threadgill DW, Tarantino LM, Miller DR, Zou F, McMillan L, Sullivan PF, Pardo-Manuel de Villena F.

Nat Genet. 2015 Apr;47(4):353-60. doi: 10.1038/ng.3222. Epub 2015 Mar 2. Erratum in: Nat Genet. 2015 Jun;47(6):690.

21.

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

PLoS Genet. 2015 Feb 13;11(2):e1004850. doi: 10.1371/journal.pgen.1004850. eCollection 2015 Feb.

22.

Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.

Chandler RL, Damrauer JS, Raab JR, Schisler JC, Wilkerson MD, Didion JP, Starmer J, Serber D, Yee D, Xiong J, Darr DB, Pardo-Manuel de Villena F, Kim WY, Magnuson T.

Nat Commun. 2015 Jan 27;6:6118. doi: 10.1038/ncomms7118.

23.

Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression.

Xiong H, Morrison J, Ferris MT, Gralinski LE, Whitmore AC, Green R, Thomas MJ, Tisoncik-Go J, Schroth GP, Pardo-Manuel de Villena F, Baric RS, Heise MT, Peng X, Katze MG.

G3 (Bethesda). 2014 Jun 5;4(8):1429-44. doi: 10.1534/g3.114.011759.

24.

Integrative genetic analysis of allergic inflammation in the murine lung.

Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS.

Am J Respir Cell Mol Biol. 2014 Sep;51(3):436-45. doi: 10.1165/rcmb.2013-0501OC.

25.

High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline.

Liu EY, Morgan AP, Chesler EJ, Wang W, Churchill GA, Pardo-Manuel de Villena F.

Genetics. 2014 May;197(1):91-106. doi: 10.1534/genetics.114.161653. Epub 2014 Feb 27.

26.

A novel statistical approach for jointly analyzing RNA-Seq data from F1 reciprocal crosses and inbred lines.

Zou F, Sun W, Crowley JJ, Zhabotynsky V, Sullivan PF, Pardo-Manuel de Villena F.

Genetics. 2014 May;197(1):389-99. doi: 10.1534/genetics.113.160119. Epub 2014 Feb 21.

27.

Genetic architecture of skewed X inactivation in the laboratory mouse.

Calaway JD, Lenarcic AB, Didion JP, Wang JR, Searle JB, McMillan L, Valdar W, Pardo-Manuel de Villena F.

PLoS Genet. 2013;9(10):e1003853. doi: 10.1371/journal.pgen.1003853. Epub 2013 Oct 3.

28.

A novel intronic single nucleotide polymorphism in the myosin heavy polypeptide 4 gene is responsible for the mini-muscle phenotype characterized by major reduction in hind-limb muscle mass in mice.

Kelly SA, Bell TA, Selitsky SR, Buus RJ, Hua K, Weinstock GM, Garland T Jr, Pardo-Manuel de Villena F, Pomp D.

Genetics. 2013 Dec;195(4):1385-95. doi: 10.1534/genetics.113.154476. Epub 2013 Sep 20.

29.

GeneScissors: a comprehensive approach to detecting and correcting spurious transcriptome inference owing to RNA-seq reads misalignment.

Zhang Z, Huang S, Wang J, Zhang X, Pardo Manuel de Villena F, McMillan L, Wang W.

Bioinformatics. 2013 Jul 1;29(13):i291-9. doi: 10.1093/bioinformatics/btt216.

30.

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.

Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, Wang J, Churchill GA, Threadgill DW, McWeeney SK, Katze MG, Pardo-Manuel de Villena F, Baric RS, Heise MT.

PLoS Pathog. 2013 Feb;9(2):e1003196. doi: 10.1371/journal.ppat.1003196. Epub 2013 Feb 28.

31.

Intronic parent-of-origin dependent differential methylation at the Actn1 gene is conserved in rodents but is not associated with imprinted expression.

Calaway JD, Domínguez JI, Hanson ME, Cambranis EC, Pardo-Manuel de Villena F, de la Casa-Esperon E.

PLoS One. 2012;7(11):e48936. doi: 10.1371/journal.pone.0048936. Epub 2012 Nov 8.

32.

Transcriptome atlases of mouse brain reveals differential expression across brain regions and genetic backgrounds.

Sun W, Lee S, Zhabotynsky V, Zou F, Wright FA, Crowley JJ, Yun Z, Buus RJ, Miller DR, Wang J, McMillan L, Pardo-Manuel de Villena F, Sullivan PF.

G3 (Bethesda). 2012 Feb;2(2):203-11. doi: 10.1534/g3.111.001602. Epub 2012 Feb 1.

33.

Genetic analysis of hematological parameters in incipient lines of the collaborative cross.

Kelada SN, Aylor DL, Peck BC, Ryan JF, Tavarez U, Buus RJ, Miller DR, Chesler EJ, Threadgill DW, Churchill GA, Pardo-Manuel de Villena F, Collins FS.

G3 (Bethesda). 2012 Feb;2(2):157-65. doi: 10.1534/g3.111.001776. Epub 2012 Feb 1.

34.

A comparative survey of the frequency and distribution of polymorphism in the genome of Xenopus tropicalis.

Showell C, Carruthers S, Hall A, Pardo-Manuel de Villena F, Stemple D, Conlon FL.

PLoS One. 2011;6(8):e22392. doi: 10.1371/journal.pone.0022392. Epub 2011 Aug 4.

35.

Genetic architecture of voluntary exercise in an advanced intercross line of mice.

Kelly SA, Nehrenberg DL, Peirce JL, Hua K, Steffy BM, Wiltshire T, Pardo-Manuel de Villena F, Garland T Jr, Pomp D.

Physiol Genomics. 2010 Jul 7;42(2):190-200. doi: 10.1152/physiolgenomics.00028.2010. Epub 2010 Apr 13.

36.

TreeQA: quantitative genome wide association mapping using local perfect phylogeny trees.

Pan F, McMillan L, Pardo-Manuel De Villena F, Threadgill D, Wang W.

Pac Symp Biocomput. 2009:415-26.

37.

Inferring genome-wide mosaic structure.

Zhang Q, Wang W, McMillan L, Pardo-Manuel De Villena F, Threadgill D.

Pac Symp Biocomput. 2009:150-61.

38.

An imputed genotype resource for the laboratory mouse.

Szatkiewicz JP, Beane GL, Ding Y, Hutchins L, Pardo-Manuel de Villena F, Churchill GA.

Mamm Genome. 2008 Mar;19(3):199-208. doi: 10.1007/s00335-008-9098-9. Epub 2008 Feb 27.

39.

The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics.

Roberts A, Pardo-Manuel de Villena F, Wang W, McMillan L, Threadgill DW.

Mamm Genome. 2007 Jul;18(6-7):473-81. Epub 2007 Aug 3.

40.

On the subspecific origin of the laboratory mouse.

Yang H, Bell TA, Churchill GA, Pardo-Manuel de Villena F.

Nat Genet. 2007 Sep;39(9):1100-7. Epub 2007 Jul 29.

PMID:
17660819
41.

Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15.

Wilson W 3rd, Pardo-Manuel de Villena F, Lyn-Cook BD, Chatterjee PK, Bell TA, Detwiler DA, Gilmore RC, Valladeras IC, Wright CC, Threadgill DW, Grant DJ.

Genomics. 2004 Oct;84(4):707-14.

PMID:
15475248
42.

X chromosome effect on maternal recombination and meiotic drive in the mouse.

de La Casa-Esperón E, Loredo-Osti JC, Pardo-Manuel de Villena F, Briscoe TL, Malette JM, Vaughan JE, Morgan K, Sapienza C.

Genetics. 2002 Aug;161(4):1651-9.

43.

Female meiosis drives karyotypic evolution in mammals.

Pardo-Manuel de Villena F, Sapienza C.

Genetics. 2001 Nov;159(3):1179-89. Erratum in: Genetics 2002 Mar;160(3):1263.

44.

Transmission of Robertsonian chromosomes through human female meiosis.

Pardo-Manuel de Villena F, Sapienza C.

Cytogenet Cell Genet. 2001;92(3-4):342-4. No abstract available.

PMID:
11435710
45.

Nonrandom segregation during meiosis: the unfairness of females.

Pardo-Manuel de Villena F, Sapienza C.

Mamm Genome. 2001 May;12(5):331-9. Review.

PMID:
11331939
46.

Recombination is proportional to the number of chromosome arms in mammals.

Pardo-Manuel de Villena F, Sapienza C.

Mamm Genome. 2001 Apr;12(4):318-22. No abstract available.

PMID:
11309665
47.

Transmission ratio distortion in offspring of heterozygous female carriers of Robertsonian translocations.

Pardo-Manuel de Villena F, Sapienza C.

Hum Genet. 2001 Jan;108(1):31-6.

PMID:
11214904
48.

H2-haplotype-dependent unequal transmission of the 17(16) translocation chromosome from Ts65Dn females.

Paz-Miguel JE, Pardo-Manuel de Villena F, Sánchez-Velasco P, Leyva-Cobián F.

Mamm Genome. 2001 Jan;12(1):83-5. No abstract available.

PMID:
11178750
49.

Natural selection and the function of genome imprinting: beyond the silenced minority.

Pardo-Manuel de Villena F, de la Casa-Esperón E, Sapienza C.

Trends Genet. 2000 Dec;16(12):573-9. Review.

PMID:
11102708
50.

Heritability of the maternal meiotic drive system linked to Om and high-resolution mapping of the Responder locus in mouse.

Pardo-Manuel De Villena F, de La Casa-Esperón E, Williams JW, Malette JM, Rosa M, Sapienza C.

Genetics. 2000 May;155(1):283-9.

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