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Items: 1 to 50 of 95

1.

COP9 signalosome complex subunit 5, an IFT20 binding partner, is essential to maintain male germ cell survival and acrosome biogenesis.

Huang Q, Liu H, Zeng J, Li W, Zhang S, Zhang L, Song S, Zhou T, Sutoysky M, Sutoysky P, Pardi R, Hess RA, Zhang Z.

Biol Reprod. 2019 Aug 2. pii: ioz154. doi: 10.1093/biolre/ioz154. [Epub ahead of print]

PMID:
31373619
2.

Fecal microbiota transplant via colonoscopy may be preferred due to intraprocedure findings.

Cho JM, Pestana L, Pardi R, Pardi DS, Khanna S.

Intest Res. 2019 Jul;17(3):434-437. doi: 10.5217/ir.2019.00056. Epub 2019 May 31. No abstract available.

3.

Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway.

Cornelius RJ, Si J, Cuevas CA, Nelson JW, Gratreak BDK, Pardi R, Yang CL, Ellison DH.

J Am Soc Nephrol. 2018 Nov;29(11):2627-2640. doi: 10.1681/ASN.2018030333. Epub 2018 Oct 9.

4.

T cell LFA-1-induced proinflammatory mRNA stabilization is mediated by the p38 pathway kinase MK2 in a process regulated by hnRNPs C, H1 and K.

Rao GK, Wong A, Collinge M, Sarhan J, Yarovinsky TO, Ramgolam VS, Gaestel M, Pardi R, Bender JR.

PLoS One. 2018 Jul 26;13(7):e0201103. doi: 10.1371/journal.pone.0201103. eCollection 2018.

5.

Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.

Asare Y, Ommer M, Azombo FA, Alampour-Rajabi S, Sternkopf M, Sanati M, Gijbels MJ, Schmitz C, Sinitski D, Tilstam PV, Lue H, Gessner A, Lange D, Schmid JA, Weber C, Dichgans M, Jankowski J, Pardi R, de Winther MP, Noels H, Bernhagen J.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):E2766-E2775. doi: 10.1073/pnas.1618411114. Epub 2017 Mar 14.

6.

Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production.

Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi MM, Bender JR, Morrison AR.

Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):328-340. doi: 10.1161/ATVBAHA.116.308507. Epub 2016 Nov 10.

7.

A novel device to concurrently assess leukocyte extravasation and interstitial migration within a defined 3D environment.

Molteni R, Bianchi E, Patete P, Fabbri M, Baroni G, Dubini G, Pardi R.

Lab Chip. 2015 Jan 7;15(1):195-207. doi: 10.1039/c4lc00741g.

PMID:
25337693
8.

Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.

Morrison AR, Yarovinsky TO, Young BD, Moraes F, Ross TD, Ceneri N, Zhang J, Zhuang ZW, Sinusas AJ, Pardi R, Schwartz MA, Simons M, Bender JR.

J Exp Med. 2014 Sep 22;211(10):1957-68. doi: 10.1084/jem.20132130. Epub 2014 Sep 1.

9.

The PAR complex controls the spatiotemporal dynamics of F-actin and the MTOC in directionally migrating leukocytes.

Crespo CL, Vernieri C, Keller PJ, Garrè M, Bender JR, Wittbrodt J, Pardi R.

J Cell Sci. 2014 Oct 15;127(Pt 20):4381-95. doi: 10.1242/jcs.146217. Epub 2014 Sep 1.

10.

Loss of jab1 in osteochondral progenitor cells severely impairs embryonic limb development in mice.

Bashur LA, Chen D, Chen Z, Liang B, Pardi R, Murakami S, Zhou G.

J Cell Physiol. 2014 Nov;229(11):1607-17. doi: 10.1002/jcp.24602.

11.

The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver.

Panattoni M, Maiorino L, Lukacs A, Zentilin L, Mazza D, Sanvito F, Sitia G, Guidotti LG, Pardi R.

Hepatology. 2014 Jun;59(6):2331-43. doi: 10.1002/hep.27028. Epub 2014 Apr 30.

PMID:
24452456
12.

Jab1 regulates Schwann cell proliferation and axonal sorting through p27.

Porrello E, Rivellini C, Dina G, Triolo D, Del Carro U, Ungaro D, Panattoni M, Feltri ML, Wrabetz L, Pardi R, Quattrini A, Previtali SC.

J Exp Med. 2014 Jan 13;211(1):29-43. doi: 10.1084/jem.20130720. Epub 2013 Dec 16.

13.

The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivo.

Chen D, Bashur LA, Liang B, Panattoni M, Tamai K, Pardi R, Zhou G.

J Cell Sci. 2013 Jan 1;126(Pt 1):234-43. doi: 10.1242/jcs.113795. Epub 2012 Nov 30.

14.

Microfluidics for in vitro biomimetic shear stress-dependent leukocyte adhesion assays.

Bianchi E, Molteni R, Pardi R, Dubini G.

J Biomech. 2013 Jan 18;46(2):276-83. doi: 10.1016/j.jbiomech.2012.10.024. Epub 2012 Nov 30. Review.

PMID:
23200903
15.

JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression.

Sitte S, Gläsner J, Jellusova J, Weisel F, Panattoni M, Pardi R, Gessner A.

J Immunol. 2012 Mar 15;188(6):2677-86. doi: 10.4049/jimmunol.1101455. Epub 2012 Feb 10.

16.

Macrophage β2 integrin-mediated, HuR-dependent stabilization of angiogenic factor-encoding mRNAs in inflammatory angiogenesis.

Zhang J, Modi Y, Yarovinsky T, Yu J, Collinge M, Kyriakides T, Zhu Y, Sessa WC, Pardi R, Bender JR.

Am J Pathol. 2012 Apr;180(4):1751-60. doi: 10.1016/j.ajpath.2011.12.025. Epub 2012 Feb 7.

17.

Plant homologue constitutive photomorphogenesis 9 (COP9) signalosome subunit CSN5 regulates innate immune responses in macrophages.

Deng Z, Pardi R, Cheadle W, Xiang X, Zhang S, Shah SV, Grizzle W, Miller D, Mountz J, Zhang HG.

Blood. 2011 May 5;117(18):4796-804. doi: 10.1182/blood-2010-10-314526. Epub 2011 Mar 14.

PMID:
21403132
18.

T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade.

Ramgolam VS, DeGregorio SD, Rao GK, Collinge M, Subaran SS, Markovic-Plese S, Pardi R, Bender JR.

PLoS One. 2010 Dec 29;5(12):e14450. doi: 10.1371/journal.pone.0014450.

19.

CSN5/Jab1 controls multiple events in the mammalian cell cycle.

Yoshida A, Yoneda-Kato N, Panattoni M, Pardi R, Kato JY.

FEBS Lett. 2010 Nov 19;584(22):4545-52. doi: 10.1016/j.febslet.2010.10.039. Epub 2010 Oct 26.

20.

Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected].

Penzo M, Molteni R, Suda T, Samaniego S, Raucci A, Habiel DM, Miller F, Jiang HP, Li J, Pardi R, Palumbo R, Olivotto E, Kew RR, Bianchi ME, Marcu KB.

J Immunol. 2010 Apr 15;184(8):4497-509. doi: 10.4049/jimmunol.0903131. Epub 2010 Mar 15. Erratum in: J Immunol. 2010 Jun 15;184(12):7314.

21.

The GIT-PIX complexes regulate the chemotactic response of rat basophilic leukaemia cells.

Gavina M, Za L, Molteni R, Pardi R, de Curtis I.

Biol Cell. 2010 Jan 14;102(4):231-44. doi: 10.1042/BC20090074.

22.

Laser capture microdissection as a new tool to assess graft-infiltrating lymphocytes gene profile in islet transplantation.

Vergani A, Clissi B, Sanvito F, Doglioni C, Fiorina P, Pardi R.

Cell Transplant. 2009;18(8):827-32. doi: 10.3727/096368909X472278. Epub 2009 Sep 28.

PMID:
19785935
23.

Beta-arrestin 2 is required for the induction and strengthening of integrin-mediated leukocyte adhesion during CXCR2-driven extravasation.

Molteni R, Crespo CL, Feigelson S, Moser C, Fabbri M, Grabovsky V, Krombach F, Laudanna C, Alon R, Pardi R.

Blood. 2009 Jul 30;114(5):1073-82. doi: 10.1182/blood-2008-10-183699. Epub 2009 May 8.

PMID:
19429870
24.

JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling.

Cera MR, Fabbri M, Molendini C, Corada M, Orsenigo F, Rehberg M, Reichel CA, Krombach F, Pardi R, Dejana E.

J Cell Sci. 2009 Jan 15;122(Pt 2):268-77. doi: 10.1242/jcs.037127.

25.

Ligand-engaged urokinase-type plasminogen activator receptor and activation of the CD11b/CD18 integrin inhibit late events of HIV expression in monocytic cells.

Alfano M, Mariani SA, Elia C, Pardi R, Blasi F, Poli G.

Blood. 2009 Feb 19;113(8):1699-709. doi: 10.1182/blood-2008-02-138412. Epub 2008 Oct 21.

26.

Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development.

Panattoni M, Sanvito F, Basso V, Doglioni C, Casorati G, Montini E, Bender JR, Mondino A, Pardi R.

J Exp Med. 2008 Feb 18;205(2):465-77. doi: 10.1084/jem.20070725. Epub 2008 Feb 11.

27.

COP1D, an alternatively spliced constitutive photomorphogenic-1 (COP1) product, stabilizes UV stress-induced c-Jun through inhibition of full-length COP1.

Savio MG, Rotondo G, Maglie S, Rossetti G, Bender JR, Pardi R.

Oncogene. 2008 Apr 10;27(17):2401-11. Epub 2007 Oct 29.

PMID:
17968316
28.

Pathophysiology of leukocyte-tissue interactions.

Molteni R, Fabbri M, Bender JR, Pardi R.

Curr Opin Cell Biol. 2006 Oct;18(5):491-8. Epub 2006 Aug 9. Review.

PMID:
16904306
29.

LFA-1-dependent HuR nuclear export and cytokine mRNA stabilization in T cell activation.

Wang JG, Collinge M, Ramgolam V, Ayalon O, Fan XC, Pardi R, Bender JR.

J Immunol. 2006 Feb 15;176(4):2105-13.

30.

Dynamic partitioning into lipid rafts controls the endo-exocytic cycle of the alphaL/beta2 integrin, LFA-1, during leukocyte chemotaxis.

Fabbri M, Di Meglio S, Gagliani MC, Consonni E, Molteni R, Bender JR, Tacchetti C, Pardi R.

Mol Biol Cell. 2005 Dec;16(12):5793-803. Epub 2005 Oct 5.

31.

Synaptic clusters of MHC class II molecules induced on DCs by adhesion molecule-mediated initial T-cell scanning.

de la Fuente H, Mittelbrunn M, Sánchez-Martín L, Vicente-Manzanares M, Lamana A, Pardi R, Cabañas C, Sánchez-Madrid F.

Mol Biol Cell. 2005 Jul;16(7):3314-22. Epub 2005 May 4.

32.

Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8.

Carrabino S, Carminati E, Talarico D, Pardi R, Bianchi E.

Gene Expr Patterns. 2004 Jul;4(4):423-31.

PMID:
15183309
33.

RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1.

Denti S, Sirri A, Cheli A, Rogge L, Innamorati G, Putignano S, Fabbri M, Pardi R, Bianchi E.

J Biol Chem. 2004 Mar 26;279(13):13027-34. Epub 2004 Jan 13.

34.

The critical cytoplasmic regions of the alphaL/beta2 integrin in Rap1-induced adhesion and migration.

Tohyama Y, Katagiri K, Pardi R, Lu C, Springer TA, Kinashi T.

Mol Biol Cell. 2003 Jun;14(6):2570-82. Epub 2003 Mar 7.

35.

T lymphocytes.

Fabbri M, Smart C, Pardi R.

Int J Biochem Cell Biol. 2003 Jul;35(7):1004-8. Review.

PMID:
12672468
36.

Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity.

Bianchi E, Denti S, Catena R, Rossetti G, Polo S, Gasparian S, Putignano S, Rogge L, Pardi R.

J Biol Chem. 2003 May 30;278(22):19682-90. Epub 2003 Mar 3.

37.

Macrophages exposed to Mycobacterium tuberculosis release chemokines able to recruit selected leucocyte subpopulations: focus on gammadelta cells.

Ferrero E, Biswas P, Vettoretto K, Ferrarini M, Uguccioni M, Piali L, Leone BE, Moser B, Rugarli C, Pardi R.

Immunology. 2003 Mar;108(3):365-74.

38.

Integrin-dependent regulation of gene expression in leukocytes.

Rossetti G, Collinge M, Bender JR, Molteni R, Pardi R.

Immunol Rev. 2002 Aug;186:189-207. Review.

PMID:
12234372
39.

Inhibition of interferon-gamma-mediated microvascular endothelial cell major histocompatibility complex class II gene activation by HMG-CoA reductase inhibitors.

Sadeghi MM, Tiglio A, Sadigh K, O'Donnell L, Collinge M, Pardi R, Bender JR.

Transplantation. 2001 May 15;71(9):1262-8.

PMID:
11397960
40.
41.
42.

Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity.

Bianchi E, Denti S, Granata A, Bossi G, Geginat J, Villa A, Rogge L, Pardi R.

Nature. 2000 Apr 6;404(6778):617-21.

PMID:
10766246
43.

CD28 and LFA-1 contribute to cyclosporin A-resistant T cell growth by stabilizing the IL-2 mRNA through distinct signaling pathways.

Geginat J, Clissi B, Moro M, Dellabona P, Bender JR, Pardi R.

Eur J Immunol. 2000 Apr;30(4):1136-44.

44.

Localization of Th-cell subsets in inflammation: differential thresholds for extravasation of Th1 and Th2 cells.

D'Ambrosio D, Iellem A, Colantonio L, Clissi B, Pardi R, Sinigaglia F.

Immunol Today. 2000 Apr;21(4):183-6. Review. No abstract available.

PMID:
10740239
45.

Chemokines fail to up-regulate beta 1 integrin-dependent adhesion in human Th2 T lymphocytes.

Clissi B, D'Ambrosio D, Geginat J, Colantonio L, Morrot A, Freshney NW, Downward J, Sinigaglia F, Pardi R.

J Immunol. 2000 Mar 15;164(6):3292-300.

46.
47.

Upregulation of integrin alpha6/beta1 and chemokine receptor CCR1 by interleukin-12 promotes the migration of human type 1 helper T cells.

Colantonio L, Iellem A, Clissi B, Pardi R, Rogge L, Sinigaglia F, D'Ambrosio D.

Blood. 1999 Nov 1;94(9):2981-9.

PMID:
10556180
48.
49.

Regulation of lymphocyte traffic by adhesion molecules.

Fabbri M, Bianchi E, Fumagalli L, Pardi R.

Inflamm Res. 1999 May;48(5):239-46. Review.

PMID:
10391111
50.

Anchorage dependence of mitogen-induced G1 to S transition in primary T lymphocytes.

Geginat J, Bossi G, Bender JR, Pardi R.

J Immunol. 1999 May 1;162(9):5085-93.

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