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Items: 20

1.

Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice.

Willis E, Pardi N, Parkhouse K, Mui BL, Tam YK, Weissman D, Hensley SE.

Sci Transl Med. 2020 Jan 8;12(525). pii: eaav5701. doi: 10.1126/scitranslmed.aav5701.

PMID:
31915303
2.

Nucleoside-modified mRNA encoding HSV-2 glycoproteins C, D, and E prevents clinical and subclinical genital herpes.

Awasthi S, Hook LM, Pardi N, Wang F, Myles A, Cancro MP, Cohen GH, Weissman D, Friedman HM.

Sci Immunol. 2019 Sep 20;4(39). pii: eaaw7083. doi: 10.1126/sciimmunol.aaw7083.

PMID:
31541030
3.

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques.

Pardi N, LaBranche CC, Ferrari G, Cain DW, Tombácz I, Parks RJ, Muramatsu H, Mui BL, Tam YK, Karikó K, Polacino P, Barbosa CJ, Madden TD, Hope MJ, Haynes BF, Montefiori DC, Hu SL, Weissman D.

Mol Ther Nucleic Acids. 2019 Apr 15;15:36-47. doi: 10.1016/j.omtn.2019.03.003. Epub 2019 Mar 21.

4.

PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake.

Parhiz H, Shuvaev VV, Pardi N, Khoshnejad M, Kiseleva RY, Brenner JS, Uhler T, Tuyishime S, Mui BL, Tam YK, Madden TD, Hope MJ, Weissman D, Muzykantov VR.

J Control Release. 2018 Dec 10;291:106-115. doi: 10.1016/j.jconrel.2018.10.015. Epub 2018 Oct 15.

5.

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies.

Pardi N, Parkhouse K, Kirkpatrick E, McMahon M, Zost SJ, Mui BL, Tam YK, Karikó K, Barbosa CJ, Madden TD, Hope MJ, Krammer F, Hensley SE, Weissman D.

Nat Commun. 2018 Aug 22;9(1):3361. doi: 10.1038/s41467-018-05482-0.

6.

Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response.

Foster JB, Choudhari N, Perazzelli J, Storm J, Hofmann TJ, Jain P, Storm PB, Pardi N, Weissman D, Waanders AJ, Grupp SA, Karikó K, Resnick AC, Barrett DM.

Hum Gene Ther. 2019 Feb;30(2):168-178. doi: 10.1089/hum.2018.145. Epub 2018 Oct 2.

7.

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

Pardi N, Hogan MJ, Naradikian MS, Parkhouse K, Cain DW, Jones L, Moody MA, Verkerke HP, Myles A, Willis E, LaBranche CC, Montefiori DC, Lobby JL, Saunders KO, Liao HX, Korber BT, Sutherland LL, Scearce RM, Hraber PT, Tombácz I, Muramatsu H, Ni H, Balikov DA, Li C, Mui BL, Tam YK, Krammer F, Karikó K, Polacino P, Eisenlohr LC, Madden TD, Hope MJ, Lewis MG, Lee KK, Hu SL, Hensley SE, Cancro MP, Haynes BF, Weissman D.

J Exp Med. 2018 Jun 4;215(6):1571-1588. doi: 10.1084/jem.20171450. Epub 2018 May 8.

8.

New Kids on the Block: RNA-Based Influenza Virus Vaccines.

Scorza FB, Pardi N.

Vaccines (Basel). 2018 Apr 1;6(2). pii: E20. doi: 10.3390/vaccines6020020. Review.

9.

mRNA vaccines - a new era in vaccinology.

Pardi N, Hogan MJ, Porter FW, Weissman D.

Nat Rev Drug Discov. 2018 Apr;17(4):261-279. doi: 10.1038/nrd.2017.243. Epub 2018 Jan 12. Review.

10.

Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization.

Hogan MJ, Conde-Motter A, Jordan APO, Yang L, Cleveland B, Guo W, Romano J, Ni H, Pardi N, LaBranche CC, Montefiori DC, Hu SL, Hoxie JA, Weissman D.

Virology. 2018 Jan 15;514:106-117. doi: 10.1016/j.virol.2017.10.013. Epub 2017 Nov 22.

11.

Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge.

Pardi N, Secreto AJ, Shan X, Debonera F, Glover J, Yi Y, Muramatsu H, Ni H, Mui BL, Tam YK, Shaheen F, Collman RG, Karikó K, Danet-Desnoyers GA, Madden TD, Hope MJ, Weissman D.

Nat Commun. 2017 Mar 2;8:14630. doi: 10.1038/ncomms14630.

12.

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination.

Pardi N, Hogan MJ, Pelc RS, Muramatsu H, Andersen H, DeMaso CR, Dowd KA, Sutherland LL, Scearce RM, Parks R, Wagner W, Granados A, Greenhouse J, Walker M, Willis E, Yu JS, McGee CE, Sempowski GD, Mui BL, Tam YK, Huang YJ, Vanlandingham D, Holmes VM, Balachandran H, Sahu S, Lifton M, Higgs S, Hensley SE, Madden TD, Hope MJ, Karikó K, Santra S, Graham BS, Lewis MG, Pierson TC, Haynes BF, Weissman D.

Nature. 2017 Mar 9;543(7644):248-251. doi: 10.1038/nature21428. Epub 2017 Feb 2.

13.

Measuring the Adjuvant Activity of RNA Vaccines.

Pardi N, Weissman D.

Methods Mol Biol. 2017;1499:143-153.

PMID:
27987147
14.

Nucleoside Modified mRNA Vaccines for Infectious Diseases.

Pardi N, Weissman D.

Methods Mol Biol. 2017;1499:109-121.

PMID:
27987145
15.

Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes.

Pardi N, Tuyishime S, Muramatsu H, Kariko K, Mui BL, Tam YK, Madden TD, Hope MJ, Weissman D.

J Control Release. 2015 Nov 10;217:345-51. doi: 10.1016/j.jconrel.2015.08.007. Epub 2015 Aug 8.

16.

HPLC purification of in vitro transcribed long RNA.

Weissman D, Pardi N, Muramatsu H, Karikó K.

Methods Mol Biol. 2013;969:43-54. doi: 10.1007/978-1-62703-260-5_3.

PMID:
23296926
17.

In vitro transcription of long RNA containing modified nucleosides.

Pardi N, Muramatsu H, Weissman D, Karikó K.

Methods Mol Biol. 2013;969:29-42. doi: 10.1007/978-1-62703-260-5_2. Review.

PMID:
23296925
18.

In vivo effects of abolishing the single canonical sumoylation site in the C-terminal region of Drosophila p53.

Pardi N, Vámos E, Ujfaludi Z, Komonyi O, Bodai L, Boros IM.

Acta Biol Hung. 2011 Dec;62(4):397-412. doi: 10.1556/ABiol.62.2011.4.6.

PMID:
22119869
19.

TATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its function.

Bereczki O, Ujfaludi Z, Pardi N, Nagy Z, Tora L, Boros IM, Balint E.

BMC Mol Biol. 2008 Jun 12;9:57. doi: 10.1186/1471-2199-9-57.

20.

Daxx-like protein of Drosophila interacts with Dmp53 and affects longevity and Ark mRNA level.

Bodai L, Pardi N, Ujfaludi Z, Bereczki O, Komonyi O, Balint E, Boros IM.

J Biol Chem. 2007 Dec 14;282(50):36386-93. Epub 2007 Oct 12.

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