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Items: 18


Synthetic Biology Goes Cell-Free.

Tinafar A, Jaenes K, Pardee K.

BMC Biol. 2019 Aug 8;17(1):64. doi: 10.1186/s12915-019-0685-x. Review.


Perspective: Solidifying the impact of cell-free synthetic biology through lyophilization.

Pardee K.

Biochem Eng J. 2018 Oct 15;138:91-97. doi: 10.1016/j.bej.2018.07.008.


BioBits™ Bright: A fluorescent synthetic biology education kit.

Stark JC, Huang A, Nguyen PQ, Dubner RS, Hsu KJ, Ferrante TC, Anderson M, Kanapskyte A, Mucha Q, Packett JS, Patel P, Patel R, Qaq D, Zondor T, Burke J, Martinez T, Miller-Berry A, Puppala A, Reichert K, Schmid M, Brand L, Hill LR, Chellaswamy JF, Faheem N, Fetherling S, Gong E, Gonzalzles EM, Granito T, Koritsaris J, Nguyen B, Ottman S, Palffy C, Patel A, Skweres S, Slaton A, Woods T, Donghia N, Pardee K, Collins JJ, Jewett MC.

Sci Adv. 2018 Aug 1;4(8):eaat5107. doi: 10.1126/sciadv.aat5107. eCollection 2018 Aug.


BioBits™ Explorer: A modular synthetic biology education kit.

Huang A, Nguyen PQ, Stark JC, Takahashi MK, Donghia N, Ferrante T, Dy AJ, Hsu KJ, Dubner RS, Pardee K, Jewett MC, Collins JJ.

Sci Adv. 2018 Aug 1;4(8):eaat5105. doi: 10.1126/sciadv.aat5105. eCollection 2018 Aug.


Portable, On-Demand Biomolecular Manufacturing.

Pardee K, Slomovic S, Nguyen PQ, Lee JW, Donghia N, Burrill D, Ferrante T, McSorley FR, Furuta Y, Vernet A, Lewandowski M, Boddy CN, Joshi NS, Collins JJ.

Cell. 2016 Sep 22;167(1):248-259.e12. doi: 10.1016/j.cell.2016.09.013.


Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components.

Pardee K, Green AA, Takahashi MK, Braff D, Lambert G, Lee JW, Ferrante T, Ma D, Donghia N, Fan M, Daringer NM, Bosch I, Dudley DM, O'Connor DH, Gehrke L, Collins JJ.

Cell. 2016 May 19;165(5):1255-1266. doi: 10.1016/j.cell.2016.04.059. Epub 2016 May 6.


Synthetic biology devices for in vitro and in vivo diagnostics.

Slomovic S, Pardee K, Collins JJ.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14429-35. doi: 10.1073/pnas.1508521112. Review.


Deconstructing transcriptional heterogeneity in pluripotent stem cells.

Kumar RM, Cahan P, Shalek AK, Satija R, DaleyKeyser A, Li H, Zhang J, Pardee K, Gennert D, Trombetta JJ, Ferrante TC, Regev A, Daley GQ, Collins JJ.

Nature. 2014 Dec 4;516(7529):56-61. doi: 10.1038/nature13920.


Paper-based synthetic gene networks.

Pardee K, Green AA, Ferrante T, Cameron DE, DaleyKeyser A, Yin P, Collins JJ.

Cell. 2014 Nov 6;159(4):940-54. doi: 10.1016/j.cell.2014.10.004. Epub 2014 Oct 23.


Gene networks of fully connected triads with complete auto-activation enable multistability and stepwise stochastic transitions.

Faucon PC, Pardee K, Kumar RM, Li H, Loh YH, Wang X.

PLoS One. 2014 Jul 24;9(7):e102873. doi: 10.1371/journal.pone.0102873. eCollection 2014.


Nuclear Receptors: Small Molecule Sensors that Coordinate Growth, Metabolism and Reproduction.

Pardee K, Necakov AS, Krause H.

Subcell Biochem. 2011;52:123-53. doi: 10.1007/978-90-481-9069-0_6. Review.


The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasis.

Horner MA, Pardee K, Liu S, King-Jones K, Lajoie G, Edwards A, Krause HM, Thummel CS.

Genes Dev. 2009 Dec 1;23(23):2711-6. doi: 10.1101/gad.1833609.


Nuclear receptors homo sapiens Rev-erbbeta and Drosophila melanogaster E75 are thiolate-ligated heme proteins which undergo redox-mediated ligand switching and bind CO and NO.

Marvin KA, Reinking JL, Lee AJ, Pardee K, Krause HM, Burstyn JN.

Biochemistry. 2009 Jul 28;48(29):7056-71. doi: 10.1021/bi900697c.


The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.

Pardee KI, Xu X, Reinking J, Schuetz A, Dong A, Liu S, Zhang R, Tiefenbach J, Lajoie G, Plotnikov AN, Botchkarev A, Krause HM, Edwards A.

PLoS Biol. 2009 Feb 24;7(2):e43. doi: 10.1371/journal.pbio.1000043.


The Drosophila nuclear receptor e75 contains heme and is gas responsive.

Reinking J, Lam MM, Pardee K, Sampson HM, Liu S, Yang P, Williams S, White W, Lajoie G, Edwards A, Krause HM.

Cell. 2005 Jul 29;122(2):195-207.


Structural proteomics: toward high-throughput structural biology as a tool in functional genomics.

Yee A, Pardee K, Christendat D, Savchenko A, Edwards AM, Arrowsmith CH.

Acc Chem Res. 2003 Mar;36(3):183-9.


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