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Items: 1 to 50 of 54

1.

CD44-high neural crest stem-like cells are associated with tumour aggressiveness and poor survival in neuroblastoma tumours.

Vega FM, Colmenero-Repiso A, Gómez-Muñoz MA, Rodríguez-Prieto I, Aguilar-Morante D, Ramírez G, Márquez C, Cabello R, Pardal R.

EBioMedicine. 2019 Nov;49:82-95. doi: 10.1016/j.ebiom.2019.10.041. Epub 2019 Nov 2.

2.

Progenitor Cell Heterogeneity in the Adult Carotid Body Germinal Niche.

Sobrino V, Annese V, Pardal R.

Adv Exp Med Biol. 2019;1123:19-38. doi: 10.1007/978-3-030-11096-3_3. Review.

PMID:
31016593
3.

Loss of postnatal quiescence of neural stem cells through mTOR activation upon genetic removal of cysteine string protein-α.

Nieto-González JL, Gómez-Sánchez L, Mavillard F, Linares-Clemente P, Rivero MC, Valenzuela-Villatoro M, Muñoz-Bravo JL, Pardal R, Fernández-Chacón R.

Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):8000-8009. doi: 10.1073/pnas.1817183116. Epub 2019 Mar 29.

4.

The carotid body: a physiologically relevant germinal niche in the adult peripheral nervous system.

Sobrino V, Annese V, Navarro-Guerrero E, Platero-Luengo A, Pardal R.

Cell Mol Life Sci. 2019 Mar;76(6):1027-1039. doi: 10.1007/s00018-018-2975-9. Epub 2018 Nov 29. Review.

PMID:
30498994
5.

Fast neurogenesis from carotid body quiescent neuroblasts accelerates adaptation to hypoxia.

Sobrino V, González-Rodríguez P, Annese V, López-Barneo J, Pardal R.

EMBO Rep. 2018 Mar;19(3). pii: e44598. doi: 10.15252/embr.201744598. Epub 2018 Jan 15.

6.

Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in stage 4/M neuroblastoma.

Linares-Clemente P, Aguilar-Morante D, Rodríguez-Prieto I, Ramírez G, de Torres C, Santamaría V, Pascual-Vaca D, Colmenero-Repiso A, Vega FM, Mora J, Cabello R, Márquez C, Rivas E, Pardal R.

Oncotarget. 2017 Sep 21;8(52):89775-89792. doi: 10.18632/oncotarget.21128. eCollection 2017 Oct 27.

7.

Physiological Plasticity of Neural-Crest-Derived Stem Cells in the Adult Mammalian Carotid Body.

Annese V, Navarro-Guerrero E, Rodríguez-Prieto I, Pardal R.

Cell Rep. 2017 Apr 18;19(3):471-478. doi: 10.1016/j.celrep.2017.03.065.

8.

The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo.

Vega FM, Gautier V, Fernandez-Ponce CM, Extremera MJ, Altelaar AFM, Millan J, Tellez JC, Hernandez-Campos JA, Conejero R, Bolivar J, Pardal R, Garcia-Cózar FJ, Aguado E, Heck AJR, Duran-Ruiz MC.

J Mol Cell Cardiol. 2017 Apr;105:12-23. doi: 10.1016/j.yjmcc.2017.02.001. Epub 2017 Feb 20.

PMID:
28223221
9.

Mature neurons modulate neurogenesis through chemical signals acting on neural stem cells.

Pardal R, López Barneo J.

Dev Growth Differ. 2016 Jun;58(5):456-62. doi: 10.1111/dgd.12283. Epub 2016 Apr 21. Review.

PMID:
27101323
10.

Role and therapeutic potential of vascular stem/progenitor cells in pathological neovascularisation during chronic portal hypertension.

Garcia-Pras E, Gallego J, Coch L, Mejias M, Fernandez-Miranda G, Pardal R, Bosch J, Mendez R, Fernandez M.

Gut. 2017 Jul;66(7):1306-1320. doi: 10.1136/gutjnl-2015-311157. Epub 2016 Mar 16.

PMID:
26984852
11.

AtGRP3 Is Implicated in Root Size and Aluminum Response Pathways in Arabidopsis.

Mangeon A, Pardal R, Menezes-Salgueiro AD, Duarte GL, de Seixas R, Cruz FP, Cardeal V, Magioli C, Ricachenevsky FK, Margis R, Sachetto-Martins G.

PLoS One. 2016 Mar 3;11(3):e0150583. doi: 10.1371/journal.pone.0150583. eCollection 2016.

12.

Gene Expression Profiling Supports the Neural Crest Origin of Adult Rodent Carotid Body Stem Cells and Identifies CD10 as a Marker for Mesectoderm-Committed Progenitors.

Navarro-Guerrero E, Platero-Luengo A, Linares-Clemente P, Cases I, López-Barneo J, Pardal R.

Stem Cells. 2016 Jun;34(6):1637-50. doi: 10.1002/stem.2331. Epub 2016 Mar 2.

13.

Oxygen sensing by the carotid body: mechanisms and role in adaptation to hypoxia.

López-Barneo J, González-Rodríguez P, Gao L, Fernández-Agüera MC, Pardal R, Ortega-Sáenz P.

Am J Physiol Cell Physiol. 2016 Apr 15;310(8):C629-42. doi: 10.1152/ajpcell.00265.2015. Epub 2016 Jan 13. Review.

14.

Oxygen-sensing by arterial chemoreceptors: Mechanisms and medical translation.

López-Barneo J, Ortega-Sáenz P, González-Rodríguez P, Fernández-Agüera MC, Macías D, Pardal R, Gao L.

Mol Aspects Med. 2016 Feb-Mar;47-48:90-108. doi: 10.1016/j.mam.2015.12.002. Epub 2015 Dec 18. Review.

PMID:
26709054
15.

Resistance of glia-like central and peripheral neural stem cells to genetically induced mitochondrial dysfunction--differential effects on neurogenesis.

Díaz-Castro B, Pardal R, García-Flores P, Sobrino V, Durán R, Piruat JI, López-Barneo J.

EMBO Rep. 2015 Nov;16(11):1511-9. doi: 10.15252/embr.201540982. Epub 2015 Sep 21.

16.

Carotid body oxygen sensing and adaptation to hypoxia.

López-Barneo J, Macías D, Platero-Luengo A, Ortega-Sáenz P, Pardal R.

Pflugers Arch. 2016 Jan;468(1):59-70. doi: 10.1007/s00424-015-1734-0. Epub 2015 Sep 16. Review.

PMID:
26373853
17.

Neurotrophic Properties, Chemosensory Responses and Neurogenic Niche of the Human Carotid Body.

Ortega-Sáenz P, Villadiego J, Pardal R, Toledo-Aral JJ, López-Barneo J.

Adv Exp Med Biol. 2015;860:139-52. doi: 10.1007/978-3-319-18440-1_16. Review.

PMID:
26303476
18.

Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuronal and oligodendrocyte survival.

d'Anglemont de Tassigny X, Sirerol-Piquer MS, Gómez-Pinedo U, Pardal R, Bonilla S, Capilla-Gonzalez V, López-López I, De la Torre-Laviana FJ, García-Verdugo JM, López-Barneo J.

Hypoxia (Auckl). 2015 Jun 8;3:15-33. eCollection 2015.

19.

[Study of the expression of neural stem cell markers in neuroblastoma tumor samples and correlation with prognostic factors].

Martínez-Criado Y, Cabello R, Fernández-Pineda I, Márquez C, Ramírez G, Rivas E, Robles MJ, Pardal R, Vega FM.

Cir Pediatr. 2013 Jul;26(3):112-8. Spanish.

PMID:
24482902
20.

An O2-sensitive glomus cell-stem cell synapse induces carotid body growth in chronic hypoxia.

Platero-Luengo A, González-Granero S, Durán R, Díaz-Castro B, Piruat JI, García-Verdugo JM, Pardal R, López-Barneo J.

Cell. 2014 Jan 16;156(1-2):291-303. doi: 10.1016/j.cell.2013.12.013.

21.

Cellular properties and chemosensory responses of the human carotid body.

Ortega-Sáenz P, Pardal R, Levitsky K, Villadiego J, Muñoz-Manchado AB, Durán R, Bonilla-Henao V, Arias-Mayenco I, Sobrino V, Ordóñez A, Oliver M, Toledo-Aral JJ, López-Barneo J.

J Physiol. 2013 Dec 15;591(24):6157-73. doi: 10.1113/jphysiol.2013.263657. Epub 2013 Oct 28.

22.

Neural stem cells and transplantation studies in Parkinson's disease.

Pardal R, López-Barneo J.

Adv Exp Med Biol. 2012;741:206-16. doi: 10.1007/978-1-4614-2098-9_14.

PMID:
22457112
23.

The carotid body, a neurogenic niche in the adult peripheral nervous system.

Pardal R, Ortega-Sáenz P, Durán R, Platero-Luengo A, López-Barneo J.

Arch Ital Biol. 2010 Jun;148(2):95-105. Review.

PMID:
20830972
24.

Oxygen sensing in the carotid body.

López-Barneo J, Ortega-Sáenz P, Pardal R, Pascual A, Piruat JI, Durán R, Gómez-Díaz R.

Ann N Y Acad Sci. 2009 Oct;1177:119-31. doi: 10.1111/j.1749-6632.2009.05033.x. Review.

PMID:
19845614
25.

The neurogenic niche in the carotid body and its applicability to antiparkinsonian cell therapy.

López-Barneo J, Pardal R, Ortega-Sáenz P, Durán R, Villadiego J, Toledo-Aral JJ.

J Neural Transm (Vienna). 2009 Aug;116(8):975-82. doi: 10.1007/s00702-009-0201-5. Epub 2009 Mar 5. Review.

PMID:
19263191
26.

Carotid body oxygen sensing.

López-Barneo J, Ortega-Sáenz P, Pardal R, Pascual A, Piruat JI.

Eur Respir J. 2008 Nov;32(5):1386-98. doi: 10.1183/09031936.00056408. Review.

27.

Glia-like stem cells sustain physiologic neurogenesis in the adult mammalian carotid body.

Pardal R, Ortega-Sáenz P, Durán R, López-Barneo J.

Cell. 2007 Oct 19;131(2):364-77.

28.

Understanding our own neural stem cells in situ: can we benefit from them?

Pardal R.

Front Biosci. 2007 May 1;12:3125-32.

PMID:
17485287
29.

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing.

Molofsky AV, Slutsky SG, Joseph NM, He S, Pardal R, Krishnamurthy J, Sharpless NE, Morrison SJ.

Nature. 2006 Sep 28;443(7110):448-52. Epub 2006 Sep 6.

30.

Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors.

Pardal R, Molofsky AV, He S, Morrison SJ.

Cold Spring Harb Symp Quant Biol. 2005;70:177-85. Review.

PMID:
16869752
32.

Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse.

Cachaço AS, Pereira CS, Pardal RG, Bajanca F, Thorsteinsdóttir S.

Dev Dyn. 2005 Apr;232(4):1069-78.

33.

Diverse mechanisms regulate stem cell self-renewal.

Molofsky AV, Pardal R, Morrison SJ.

Curr Opin Cell Biol. 2004 Dec;16(6):700-7. Review.

PMID:
15530784
34.

Combined oxygen and glucose sensing in the carotid body.

Pardal R, López-Barneo J.

Undersea Hyperb Med. 2004 Spring;31(1):113-21. No abstract available.

PMID:
15233167
35.

Applying the principles of stem-cell biology to cancer.

Pardal R, Clarke MF, Morrison SJ.

Nat Rev Cancer. 2003 Dec;3(12):895-902. Review. No abstract available.

PMID:
14737120
36.

Studies on glomus cell sensitivity to hypoxia in carotid body slices.

Ortega-Sáenz P, García-Fernández M, Pardal R, Alvarez E, López-Barneo J.

Adv Exp Med Biol. 2003;536:65-73. No abstract available.

PMID:
14635651
37.

Glucose sensing cells in the carotid body.

García-Fernández M, Ortega-Sáenz P, Pardal R, López-Barneo J.

Adv Exp Med Biol. 2003;536:47-53. No abstract available.

PMID:
14635648
38.

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation.

Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ.

Nature. 2003 Oct 30;425(6961):962-7. Epub 2003 Oct 22.

39.

Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes.

Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM, Fike JR, Lee HO, Pfeffer K, Lois C, Morrison SJ, Alvarez-Buylla A.

Nature. 2003 Oct 30;425(6961):968-73. Epub 2003 Oct 12.

40.

Autotransplantation of human carotid body cell aggregates for treatment of Parkinson's disease.

Arjona V, Mínguez-Castellanos A, Montoro RJ, Ortega A, Escamilla F, Toledo-Aral JJ, Pardal R, Méndez-Ferrer S, Martín JM, Pérez M, Katati MJ, Valencia E, García T, López-Barneo J.

Neurosurgery. 2003 Aug;53(2):321-8; discussion 328-30.

PMID:
12925247
41.

Hirschsprung disease is linked to defects in neural crest stem cell function.

Iwashita T, Kruger GM, Pardal R, Kiel MJ, Morrison SJ.

Science. 2003 Aug 15;301(5635):972-6.

42.

Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells.

Ortega-Sáenz P, Pardal R, García-Fernandez M, López-Barneo J.

J Physiol. 2003 May 1;548(Pt 3):789-800. Epub 2003 Mar 7.

43.

Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats.

Toledo-Aral JJ, Méndez-Ferrer S, Pardal R, Echevarría M, López-Barneo J.

J Neurosci. 2003 Jan 1;23(1):141-8.

44.

Carotid body thin slices: responses of glomus cells to hypoxia and K(+)-channel blockers.

Pardal R, López-Barneo J.

Respir Physiol Neurobiol. 2002 Aug 22;132(1):69-79. Review.

PMID:
12126696
45.

Dopaminergic cells of the carotid body: physiological significance and possible therapeutic applications in Parkinson's disease.

Toledo-Aral JJ, Méndez-Ferrer S, Pardal R, López-Barneo J.

Brain Res Bull. 2002 Apr;57(6):847-53. Review.

PMID:
12031283
46.

Low glucose-sensing cells in the carotid body.

Pardal R, López-Barneo J.

Nat Neurosci. 2002 Mar;5(3):197-8.

PMID:
11850631
47.

Cellular mechanism of oxygen sensing.

Lopez-Barneo J, Pardal R, Ortega-Sáenz P.

Annu Rev Physiol. 2001;63:259-87. Review.

PMID:
11181957
48.

Collapse of conductance is prevented by a glutamate residue conserved in voltage-dependent K(+) channels.

Ortega-Sáenz P, Pardal R, Castellano A, López-Barneo J.

J Gen Physiol. 2000 Aug;116(2):181-90.

49.

Secretory responses of intact glomus cells in thin slices of rat carotid body to hypoxia and tetraethylammonium.

Pardal R, Ludewig U, Garcia-Hirschfeld J, Lopez-Barneo J.

Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2361-6.

50.

K+ and Ca2+ channel activity and cytosolic [Ca2+] in oxygen-sensing tissues.

López-Barneo J, Pardal R, Montoro RJ, Smani T, García-Hirschfeld J, Ureña J.

Respir Physiol. 1999 Apr 1;115(2):215-27. Review.

PMID:
10385035

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