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Items: 1 to 50 of 167

1.

BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells.

Legge DN, Shephard AP, Collard TJ, Greenhough A, Chambers AC, Clarkson RW, Paraskeva C, Williams AC.

Dis Model Mech. 2019 Mar 4;12(3). pii: dmm037697. doi: 10.1242/dmm.037697.

2.

Treatment of Two-Phase Olive Mill Wastewater and Recovery of Phenolic Compounds Using Membrane Technology.

Sygouni V, Pantziaros AG, Iakovides IC, Sfetsa E, Bogdou PI, Christoforou EA, Paraskeva CA.

Membranes (Basel). 2019 Feb 5;9(2). pii: E27. doi: 10.3390/membranes9020027.

3.

Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis.

Greenhough A, Bagley C, Heesom KJ, Gurevich DB, Gay D, Bond M, Collard TJ, Paraskeva C, Martin P, Sansom OJ, Malik K, Williams AC.

EMBO Mol Med. 2018 Nov;10(11). pii: e8699. doi: 10.15252/emmm.201708699.

4.

Theoretical Insight into the Biodegradation of Solitary Oil Microdroplets Moving through a Water Column.

Kapellos GE, Paraskeva CA, Kalogerakis N, Doyle PS.

Bioengineering (Basel). 2018 Feb 12;5(1). pii: E15. doi: 10.3390/bioengineering5010015.

5.

Isolation of organic compounds with high added values from agro-industrial solid wastes.

Zagklis DP, Paraskeva CA.

J Environ Manage. 2018 Jun 15;216:183-191. doi: 10.1016/j.jenvman.2017.04.083. Epub 2017 May 2.

PMID:
28476307
6.

The Hedgehog Inhibitor Cyclopamine Reduces β-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells.

Qualtrough D, Rees P, Speight B, Williams AC, Paraskeva C.

Cancers (Basel). 2015 Sep 17;7(3):1885-99. doi: 10.3390/cancers7030867.

7.

Circulating prostaglandins as biomarkers for colorectal cancer?

Greenhough A, Paraskeva C, Williams AC.

EBioMedicine. 2015 Jan 28;2(2):105-6. doi: 10.1016/j.ebiom.2015.01.016. eCollection 2015 Feb. No abstract available.

8.

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling.

Urban BC, Collard TJ, Eagle CJ, Southern SL, Greenhough A, Hamdollah-Zadeh M, Ghosh A, Poulsom R, Paraskeva C, Silver A, Williams AC.

Gut. 2016 Jul;65(7):1151-64. doi: 10.1136/gutjnl-2014-308270. Epub 2015 Jun 1.

9.

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.

Morgan RG, Molnár E, Jones RF, Collard TJ, Lane JD, Greenhough A, Paraskeva C, Williams AC.

Br J Cancer. 2015 Feb 17;112(4):714-9. doi: 10.1038/bjc.2015.4. Epub 2015 Jan 22.

10.

Purification of olive mill wastewater phenols through membrane filtration and resin adsorption/desorption.

Zagklis DP, Vavouraki AI, Kornaros ME, Paraskeva CA.

J Hazard Mater. 2015 Mar 21;285:69-76. doi: 10.1016/j.jhazmat.2014.11.038. Epub 2014 Nov 28.

PMID:
25497019
11.

Membrane filtration of agro-industrial wastewaters and isolation of organic compounds with high added values.

Zagklis DP, Paraskeva CA.

Water Sci Technol. 2014;69(1):202-7. doi: 10.2166/wst.2013.683.

PMID:
24434988
12.

Valorization of solid waste products from olive oil industry as potential adsorbents for water pollution control--a review.

Bhatnagar A, Kaczala F, Hogland W, Marques M, Paraskeva CA, Papadakis VG, Sillanpää M.

Environ Sci Pollut Res Int. 2014 Jan;21(1):268-98. doi: 10.1007/s11356-013-2135-6. Epub 2013 Sep 26. Review.

PMID:
24068561
13.

miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance.

Zhang L, Pickard K, Jenei V, Bullock MD, Bruce A, Mitter R, Kelly G, Paraskeva C, Strefford J, Primrose J, Thomas GJ, Packham G, Mirnezami AH.

Cancer Res. 2013 Nov 1;73(21):6435-47. doi: 10.1158/0008-5472.CAN-12-3308. Epub 2013 Aug 15.

14.

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk.

Petherick KJ, Williams AC, Lane JD, Ordóñez-Morán P, Huelsken J, Collard TJ, Smartt HJ, Batson J, Malik K, Paraskeva C, Greenhough A.

EMBO J. 2013 Jul 3;32(13):1903-16. doi: 10.1038/emboj.2013.123. Epub 2013 Jun 4.

15.

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs.

Al-Kharusi MR, Smartt HJ, Greenhough A, Collard TJ, Emery ED, Williams AC, Paraskeva C.

Carcinogenesis. 2013 May;34(5):1150-7. doi: 10.1093/carcin/bgt020. Epub 2013 Jan 24.

16.

BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor β (TGF-β1) in colorectal tumour cells.

Skeen VR, Collard TJ, Southern SL, Greenhough A, Hague A, Townsend PA, Paraskeva C, Williams AC.

Oncogene. 2013 Sep 19;32(38):4490-9. doi: 10.1038/onc.2012.480. Epub 2012 Oct 29.

17.

The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells.

Collard TJ, Urban BC, Patsos HA, Hague A, Townsend PA, Paraskeva C, Williams AC.

Cell Death Dis. 2012 Oct 11;3:e408. doi: 10.1038/cddis.2012.142.

18.

β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?

Smartt HJ, Greenhough A, Ordóñez-Morán P, Al-Kharusi M, Collard TJ, Mariadason JM, Huelsken J, Williams AC, Paraskeva C.

Br J Cancer. 2012 Oct 23;107(9):1514-7. doi: 10.1038/bjc.2012.430. Epub 2012 Oct 2.

19.

TGF-β1 signalling, connecting aberrant inflammation and colorectal tumorigenesis.

Skeen VR, Paterson I, Paraskeva C, Williams AC.

Curr Pharm Des. 2012;18(26):3874-88. Review.

PMID:
22632753
20.

Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways.

Dallosso AR, Øster B, Greenhough A, Thorsen K, Curry TJ, Owen C, Hancock AL, Szemes M, Paraskeva C, Frank M, Andersen CL, Malik K.

Oncogene. 2012 Oct 4;31(40):4409-19. doi: 10.1038/onc.2011.609. Epub 2012 Jan 16.

21.

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells.

Smartt HJ, Greenhough A, Ordóñez-Morán P, Talero E, Cherry CA, Wallam CA, Parry L, Al Kharusi M, Roberts HR, Mariadason JM, Clarke AR, Huelsken J, Williams AC, Paraskeva C.

Gut. 2012 Sep;61(9):1306-14. doi: 10.1136/gutjnl-2011-300817. Epub 2011 Nov 14.

PMID:
22082586
22.

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis.

Southern SL, Collard TJ, Urban BC, Skeen VR, Smartt HJ, Hague A, Oakley F, Townsend PA, Perkins ND, Paraskeva C, Williams AC.

Oncogene. 2012 May 31;31(22):2761-72. doi: 10.1038/onc.2011.452. Epub 2011 Oct 3.

23.

Colon tumour cells increase PGE(2) by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation.

Roberts HR, Smartt HJ, Greenhough A, Moore AE, Williams AC, Paraskeva C.

Carcinogenesis. 2011 Nov;32(11):1741-7. doi: 10.1093/carcin/bgr210. Epub 2011 Sep 16.

PMID:
21926111
24.

Sand consolidation with calcium phosphate-polyelectrolyte composites.

Hafez IT, Paraskeva CA, Klepetsanis PG, Koutsoukos PG.

J Colloid Interface Sci. 2011 Nov 1;363(1):145-56. doi: 10.1016/j.jcis.2011.07.048. Epub 2011 Jul 27.

PMID:
21851950
25.

Adsorption of atrazine from aqueous electrolyte solutions on humic acid and silica.

Kovaios ID, Paraskeva CA, Koutsoukos PG.

J Colloid Interface Sci. 2011 Apr 1;356(1):277-85. doi: 10.1016/j.jcis.2011.01.002. Epub 2011 Jan 8.

PMID:
21288538
26.

The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells.

Patsos HA, Greenhough A, Hicks DJ, Al Kharusi M, Collard TJ, Lane JD, Paraskeva C, Williams AC.

Int J Oncol. 2010 Jul;37(1):187-93.

PMID:
20514410
27.

The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells.

Greenhough A, Wallam CA, Hicks DJ, Moorghen M, Williams AC, Paraskeva C.

Oncogene. 2010 Jun 10;29(23):3398-410. doi: 10.1038/onc.2010.94. Epub 2010 Mar 29.

28.

Differential expression proteomics of human colorectal cancer based on a syngeneic cellular model for the progression of adenoma to carcinoma.

Roth U, Razawi H, Hommer J, Engelmann K, Schwientek T, Müller S, Baldus SE, Patsos G, Corfield AP, Paraskeva C, Hanisch FG.

Proteomics. 2010 Jan;10(2):194-202. doi: 10.1002/pmic.200900614.

PMID:
19899082
29.

The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro.

Qualtrough D, Singh K, Banu N, Paraskeva C, Pignatelli M.

Br J Cancer. 2009 Oct 6;101(7):1124-9. doi: 10.1038/sj.bjc.6605286. Epub 2009 Sep 8.

30.

HGF/Met signalling promotes PGE(2) biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells.

Moore AE, Greenhough A, Roberts HR, Hicks DJ, Patsos HA, Williams AC, Paraskeva C.

Carcinogenesis. 2009 Oct;30(10):1796-804. doi: 10.1093/carcin/bgp183. Epub 2009 Jul 28.

PMID:
19638428
31.

Comparative analysis of PCR-based biomarker assay methods for colorectal polyp detection from fecal DNA.

Ausch C, Kim YH, Tsuchiya KD, Dzieciatkowski S, Washington MK, Paraskeva C, Radich J, Grady WM.

Clin Chem. 2009 Aug;55(8):1559-63. doi: 10.1373/clinchem.2008.122937. Epub 2009 Jun 18.

32.

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment.

Greenhough A, Smartt HJ, Moore AE, Roberts HR, Williams AC, Paraskeva C, Kaidi A.

Carcinogenesis. 2009 Mar;30(3):377-86. doi: 10.1093/carcin/bgp014. Epub 2009 Jan 9. Review.

PMID:
19136477
33.

O-glycan inhibitors generate aryl-glycans, induce apoptosis and lead to growth inhibition in colorectal cancer cell lines.

Patsos G, Hebbe-Viton V, Robbe-Masselot C, Masselot D, San Martin R, Greenwood R, Paraskeva C, Klein A, Graessmann M, Michalski JC, Gallagher T, Corfield A.

Glycobiology. 2009 Apr;19(4):382-98. doi: 10.1093/glycob/cwn149. Epub 2009 Jan 3.

PMID:
19122213
34.

Molecular aspects of carcinogenesis in pancreatic cancer.

Koliopanos A, Avgerinos C, Paraskeva C, Touloumis Z, Kelgiorgi D, Dervenis C.

Hepatobiliary Pancreat Dis Int. 2008 Aug;7(4):345-56. Review.

PMID:
18693168
35.

Persistent early organ failure: defining the high-risk group of patients with severe acute pancreatitis?

Lytras D, Manes K, Triantopoulou C, Paraskeva C, Delis S, Avgerinos C, Dervenis C.

Pancreas. 2008 Apr;36(3):249-54. doi: 10.1097/MPA.0b013e31815acb2c.

PMID:
18362837
36.

VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy.

Varey AH, Rennel ES, Qiu Y, Bevan HS, Perrin RM, Raffy S, Dixon AR, Paraskeva C, Zaccheo O, Hassan AB, Harper SJ, Bates DO.

Br J Cancer. 2008 Apr 22;98(8):1366-79. doi: 10.1038/sj.bjc.6604308. Epub 2008 Mar 18.

37.

Computation of light scattering by axisymmetric nonspherical particles and comparison with experimental results.

Constantinides GN, Gintides D, Kattis SE, Kiriaki K, Paraskeva CA, Payatakes AC, Polyzos D, Tsinopoulos SV, Yannopoulos SN.

Appl Opt. 1998 Nov 1;37(31):7310-9.

PMID:
18301564
38.

Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer.

Grady WM, Parkin RK, Mitchell PS, Lee JH, Kim YH, Tsuchiya KD, Washington MK, Paraskeva C, Willson JK, Kaz AM, Kroh EM, Allen A, Fritz BR, Markowitz SD, Tewari M.

Oncogene. 2008 Jun 19;27(27):3880-8. doi: 10.1038/onc.2008.10. Epub 2008 Feb 11.

PMID:
18264139
39.

BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity.

Clemo NK, Collard TJ, Southern SL, Edwards KD, Moorghen M, Packham G, Hague A, Paraskeva C, Williams AC.

Carcinogenesis. 2008 Apr;29(4):849-57. doi: 10.1093/carcin/bgn004. Epub 2008 Jan 19.

PMID:
18204076
40.

O-glycan regulation of apoptosis and proliferation in colorectal cancer cell lines.

Patsos G, Robbe-Masselot C, Klein A, Hebbe-Viton V, Martin RS, Masselot D, Graessmann M, Paraskeva C, Gallagher T, Corfield A.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1372-4. Review.

PMID:
17956354
41.

Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia?

Kaidi A, Moorghen M, Williams AC, Paraskeva C.

Gut. 2007 Nov;56(11):1637-8. No abstract available.

42.

Inhibition of COX-2 with NS-398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy.

Banu N, Buda A, Chell S, Elder D, Moorghen M, Paraskeva C, Qualtrough D, Pignatelli M.

Cell Prolif. 2007 Oct;40(5):768-79.

PMID:
17877615
43.

Computational representation and hemodynamic characterization of in vivo acquired severe stenotic renal artery geometries using turbulence modeling.

Kagadis GC, Skouras ED, Bourantas GC, Paraskeva CA, Katsanos K, Karnabatidis D, Nikiforidis GC.

Med Eng Phys. 2008 Jun;30(5):647-60. Epub 2007 Aug 21.

PMID:
17714975
44.
45.

Membrane filtration of olive mill wastewater and exploitation of its fractions.

Paraskeva CA, Papadakis VG, Kanellopoulou DG, Koutsoukos PG, Angelopoulos KC.

Water Environ Res. 2007 Apr;79(4):421-9.

PMID:
17489277
46.

Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells.

Qualtrough D, Kaidi A, Chell S, Jabbour HN, Williams AC, Paraskeva C.

Int J Cancer. 2007 Aug 15;121(4):734-40.

47.

Heterogeneous nucleation and growth of calcium carbonate on calcite and quartz.

Lioliou MG, Paraskeva CA, Koutsoukos PG, Payatakes AC.

J Colloid Interface Sci. 2007 Apr 15;308(2):421-8. Epub 2007 Jan 25.

PMID:
17258223
48.

Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia.

Kaidi A, Williams AC, Paraskeva C.

Nat Cell Biol. 2007 Feb;9(2):210-7. Epub 2007 Jan 14.

PMID:
17220880
49.

Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells.

H-Zadeh AM, Collard TJ, Malik K, Hicks DJ, Paraskeva C, Williams AC.

Int J Oncol. 2006 Nov;29(5):1279-86.

PMID:
17016662
50.

Calcium sulfate precipitation in the presence of water-soluble polymers.

Lioliou MG, Paraskeva CA, Koutsoukos PG, Payatakes AC.

J Colloid Interface Sci. 2006 Nov 1;303(1):164-70. Epub 2006 Jul 26.

PMID:
16920136

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