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Items: 8


A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine.

Schumann B, Hahm HS, Parameswarappa SG, Reppe K, Wahlbrink A, Govindan S, Kaplonek P, Pirofski LA, Witzenrath M, Anish C, Pereira CL, Seeberger PH.

Sci Transl Med. 2017 Mar 8;9(380). pii: eaaf5347. doi: 10.1126/scitranslmed.aaf5347.


A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection.

Parameswarappa SG, Reppe K, Geissner A, Ménová P, Govindan S, Calow ADJ, Wahlbrink A, Weishaupt MW, Monnanda BP, Bell RL, Pirofski LA, Suttorp N, Sander LE, Witzenrath M, Pereira CL, Anish C, Seeberger PH.

Cell Chem Biol. 2016 Nov 17;23(11):1407-1416. doi: 10.1016/j.chembiol.2016.09.016. Epub 2016 Nov 3.


Nucleophile-Directed Stereocontrol Over Glycosylations Using Geminal-Difluorinated Nucleophiles.

Schumann B, Parameswarappa SG, Lisboa MP, Kottari N, Guidetti F, Pereira CL, Seeberger PH.

Angew Chem Int Ed Engl. 2016 Nov 7;55(46):14431-14434. doi: 10.1002/anie.201606774. Epub 2016 Oct 13.


Improved synthesis and biological evaluation of chelator-modified α-MSH analogs prepared by copper-free click chemistry.

Baumhover NJ, Martin ME, Parameswarappa SG, Kloepping KC, O'Dorisio MS, Pigge FC, Schultz MK.

Bioorg Med Chem Lett. 2011 Oct 1;21(19):5757-61. doi: 10.1016/j.bmcl.2011.08.017. Epub 2011 Aug 8.


Titanium-mediated spirocyclization reactions of 4-alkylpyridines.

Parameswarappa SG, Pigge FC.

Org Lett. 2010 Aug 6;12(15):3434-7. doi: 10.1021/ol1012636.


A DOTA-peptide conjugate by copper-free click chemistry.

Martin ME, Parameswarappa SG, O'Dorisio MS, Pigge FC, Schultz MK.

Bioorg Med Chem Lett. 2010 Aug 15;20(16):4805-7. doi: 10.1016/j.bmcl.2010.06.111. Epub 2010 Jun 25.


Synthesis of a DOTA--biotin conjugate for radionuclide chelation via Cu-free click chemistry.

Schultz MK, Parameswarappa SG, Pigge FC.

Org Lett. 2010 May 21;12(10):2398-401. doi: 10.1021/ol100774p.

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