Sort by
Items per page

Send to

Choose Destination

Search results

Items: 39


Extracellular matrix stiffness regulates human airway smooth muscle contraction by altering the cell-cell coupling.

Polio SR, Stasiak SE, Jamieson RR, Balestrini JL, Krishnan R, Parameswaran H.

Sci Rep. 2019 Jul 2;9(1):9564. doi: 10.1038/s41598-019-45716-9.


Blood pressure-induced physiological strain variability modulates wall structure and function in aorta rings.

Imsirovic J, Bartolák-Suki E, Jawde SB, Parameswaran H, Suki B.

Physiol Meas. 2018 Oct 30;39(10):105014. doi: 10.1088/1361-6579/aae65f.


CT Imaging-Based Low-Attenuation Super Clusters in Three Dimensions and the Progression of Emphysema.

Mondoñedo JR, Sato S, Oguma T, Muro S, Sonnenberg AH, Zeldich D, Parameswaran H, Hirai T, Suki B.

Chest. 2019 Jan;155(1):79-87. doi: 10.1016/j.chest.2018.09.014. Epub 2018 Oct 5.


Assessing Structure-Function Relations in Mice Using the Forced Oscillation Technique and Quantitative Histology.

Parameswaran H, Suki B.

Methods Mol Biol. 2017;1639:77-91. doi: 10.1007/978-1-4939-7163-3_8.


Regulatory Roles of Fluctuation-Driven Mechanotransduction in Cell Function.

Suki B, Parameswaran H, Imsirovic J, Bartolák-Suki E.

Physiology (Bethesda). 2016 Sep;31(5):346-58. doi: 10.1152/physiol.00051.2015. Review.


Mechanical Forces Accelerate Collagen Digestion by Bacterial Collagenase in Lung Tissue Strips.

Yi E, Sato S, Takahashi A, Parameswaran H, Blute TA, Bartolák-Suki E, Suki B.

Front Physiol. 2016 Jul 12;7:287. doi: 10.3389/fphys.2016.00287. eCollection 2016.


Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.

Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM.

Nat Med. 2016 Feb;22(2):163-74. doi: 10.1038/nm.4021. Epub 2016 Jan 11.


Linking Ventilation Heterogeneity Quantified via Hyperpolarized 3He MRI to Dynamic Lung Mechanics and Airway Hyperresponsiveness.

Lui JK, Parameswaran H, Albert MS, Lutchen KR.

PLoS One. 2015 Nov 16;10(11):e0142738. doi: 10.1371/journal.pone.0142738. eCollection 2015.


Fluctuation-driven mechanotransduction regulates mitochondrial-network structure and function.

Bartolák-Suki E, Imsirovic J, Parameswaran H, Wellman TJ, Martinez N, Allen PG, Frey U, Suki B.

Nat Mater. 2015 Oct;14(10):1049-57. doi: 10.1038/nmat4358. Epub 2015 Jul 27.


Scale dependence of structure-function relationship in the emphysematous mouse lung.

Sato S, Bartolák-Suki E, Parameswaran H, Hamakawa H, Suki B.

Front Physiol. 2015 May 12;6:146. doi: 10.3389/fphys.2015.00146. eCollection 2015.


Can breathing-like pressure oscillations reverse or prevent narrowing of small intact airways?

Harvey BC, Parameswaran H, Lutchen KR.

J Appl Physiol (1985). 2015 Jul 1;119(1):47-54. doi: 10.1152/japplphysiol.01100.2014. Epub 2015 May 7.


Lung structure and function in elastase-treated rats: A follow-up study.

Szabari MV, Tolnai J, Maár BA, Parameswaran H, Bartolák-Suki E, Suki B, Hantos Z.

Respir Physiol Neurobiol. 2015 Aug 15;215:13-9. doi: 10.1016/j.resp.2015.04.005. Epub 2015 Apr 18.


Computational modeling helps uncover mechanisms related to the progression of emphysema.

Suki B, Parameswaran H.

Drug Discov Today Dis Models. 2014 Jul 8;70(27-28):4245-4249.


JNK suppresses pulmonary fibroblast elastogenesis during alveolar development.

Liu S, Parameswaran H, Young SM, Varisco BM.

Respir Res. 2014 Mar 25;15:34. doi: 10.1186/1465-9921-15-34.


Proteoglycans maintain lung stability in an elastase-treated mouse model of emphysema.

Takahashi A, Majumdar A, Parameswaran H, Bartolák-Suki E, Suki B.

Am J Respir Cell Mol Biol. 2014 Jul;51(1):26-33. doi: 10.1165/rcmb.2013-0179OC.


Topographical control of multiple cell adhesion molecules for traction force microscopy.

Polio SR, Parameswaran H, Canović EP, Gaut CM, Aksyonova D, Stamenović D, Smith ML.

Integr Biol (Camb). 2014 Mar;6(3):357-65. doi: 10.1039/c3ib40127h. Epub 2014 Jan 17.


A computational model of the response of adherent cells to stretch and changes in substrate stiffness.

Parameswaran H, Lutchen KR, Suki B.

J Appl Physiol (1985). 2014 Apr 1;116(7):825-34. doi: 10.1152/japplphysiol.00962.2013. Epub 2014 Jan 9.


Emphysema and mechanical stress-induced lung remodeling.

Suki B, Sato S, Parameswaran H, Szabari MV, Takahashi A, Bartolák-Suki E.

Physiology (Bethesda). 2013 Nov;28(6):404-13. doi: 10.1152/physiol.00041.2013. Review.


Can tidal breathing with deep inspirations of intact airways create sustained bronchoprotection or bronchodilation?

Harvey BC, Parameswaran H, Lutchen KR.

J Appl Physiol (1985). 2013 Aug 15;115(4):436-45. doi: 10.1152/japplphysiol.00009.2013. Epub 2013 May 30.


Semiautomatic segmentation of ventilated airspaces in healthy and asthmatic subjects using hyperpolarized 3He MRI.

Lui JK, LaPrad AS, Parameswaran H, Sun Y, Albert MS, Lutchen KR.

Comput Math Methods Med. 2013;2013:624683. doi: 10.1155/2013/624683. Epub 2013 Mar 31.


Acute mechanical forces cause deterioration in lung structure and function in elastase-induced emphysema.

Szabari MV, Parameswaran H, Sato S, Hantos Z, Bartolák-Suki E, Suki B.

Am J Physiol Lung Cell Mol Physiol. 2012 Oct 1;303(7):L567-74. doi: 10.1152/ajplung.00217.2012. Epub 2012 Aug 3.


Functional and morphological assessment of early impairment of airway function in a rat model of emphysema.

Tolnai J, Szabari MV, Albu G, Maár BA, Parameswaran H, Bartolák-Suki E, Suki B, Hantos Z.

J Appl Physiol (1985). 2012 Jun;112(11):1932-9. doi: 10.1152/japplphysiol.00587.2011. Epub 2012 Mar 22.


Jamming dynamics of stretch-induced surfactant release by alveolar type II cells.

Majumdar A, Arold SP, Bartolák-Suki E, Parameswaran H, Suki B.

J Appl Physiol (1985). 2012 Mar;112(5):824-31. doi: 10.1152/japplphysiol.00975.2010. Epub 2011 Oct 27.


Microtubule dynamics regulate cyclic stretch-induced cell alignment in human airway smooth muscle cells.

Morioka M, Parameswaran H, Naruse K, Kondo M, Sokabe M, Hasegawa Y, Suki B, Ito S.

PLoS One. 2011;6(10):e26384. doi: 10.1371/journal.pone.0026384. Epub 2011 Oct 17.


Dynamics of enzymatic digestion of elastic fibers and networks under tension.

Araújo AD, Majumdar A, Parameswaran H, Yi E, Spencer JL, Nugent MA, Suki B.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9414-9. doi: 10.1073/pnas.1019188108. Epub 2011 May 23.


Linking microscopic spatial patterns of tissue destruction in emphysema to macroscopic decline in stiffness using a 3D computational model.

Parameswaran H, Majumdar A, Suki B.

PLoS Comput Biol. 2011 Apr;7(4):e1001125. doi: 10.1371/journal.pcbi.1001125. Epub 2011 Apr 21.


Mechanical failure, stress redistribution, elastase activity and binding site availability on elastin during the progression of emphysema.

Suki B, Jesudason R, Sato S, Parameswaran H, Araujo AD, Majumdar A, Allen PG, Bartolák-Suki E.

Pulm Pharmacol Ther. 2012 Aug;25(4):268-75. doi: 10.1016/j.pupt.2011.04.027. Epub 2011 Apr 14. Review.


Structure-function relations in an elastase-induced mouse model of emphysema.

Hamakawa H, Bartolák-Suki E, Parameswaran H, Majumdar A, Lutchen KR, Suki B.

Am J Respir Cell Mol Biol. 2011 Sep;45(3):517-24. doi: 10.1165/rcmb.2010-0473OC. Epub 2010 Dec 17.


Mechanical forces regulate elastase activity and binding site availability in lung elastin.

Jesudason R, Sato S, Parameswaran H, Araujo AD, Majumdar A, Allen PG, Bartolák-Suki E, Suki B.

Biophys J. 2010 Nov 3;99(9):3076-83. doi: 10.1016/j.bpj.2010.09.018.


Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema.

Chen ZH, Lam HC, Jin Y, Kim HP, Cao J, Lee SJ, Ifedigbo E, Parameswaran H, Ryter SW, Choi AM.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18880-5. doi: 10.1073/pnas.1005574107. Epub 2010 Oct 18.


Estimating the diameter of airways susceptible for collapse using crackle sound.

Majumdar A, Hantos Z, Tolnai J, Parameswaran H, Tepper R, Suki B.

J Appl Physiol (1985). 2009 Nov;107(5):1504-12. doi: 10.1152/japplphysiol.91117.2008. Epub 2009 Sep 3.


Three-dimensional measurement of alveolar airspace volumes in normal and emphysematous lungs using micro-CT.

Parameswaran H, Bartolák-Suki E, Hamakawa H, Majumdar A, Allen PG, Suki B.

J Appl Physiol (1985). 2009 Aug;107(2):583-92. doi: 10.1152/japplphysiol.91227.2008. Epub 2009 Jun 18.


Commentaries on viewpoint: use of mean airspace chord length to assess emphysema. Pattern of parenchymal destruction determines lung function decline.

Parameswaran H, Majumdar A, Hamakawa H, Suki B.

J Appl Physiol (1985). 2008 Dec;105(6):1984; author reply 1986-7. doi: 10.1152/japplphysiol.vpcomm.zdg-8294.2008. No abstract available.


Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice.

Summer R, Little FF, Ouchi N, Takemura Y, Aprahamian T, Dwyer D, Fitzsimmons K, Suki B, Parameswaran H, Fine A, Walsh K.

Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1035-42. doi: 10.1152/ajplung.00397.2007. Epub 2008 Mar 7.


Early emphysema in the tight skin and pallid mice: roles of microfibril-associated glycoproteins, collagen, and mechanical forces.

Ito S, Bartolák-Suki E, Shipley JM, Parameswaran H, Majumdar A, Suki B.

Am J Respir Cell Mol Biol. 2006 Jun;34(6):688-94. Epub 2006 Jan 26.


Quantitative characterization of airspace enlargement in emphysema.

Parameswaran H, Majumdar A, Ito S, Alencar AM, Suki B.

J Appl Physiol (1985). 2006 Jan;100(1):186-93. Epub 2005 Sep 15.


Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: possible role of collagen remodeling.

Ito S, Ingenito EP, Brewer KK, Black LD, Parameswaran H, Lutchen KR, Suki B.

J Appl Physiol (1985). 2005 Feb;98(2):503-11. Epub 2004 Oct 1.


Tissue heterogeneity in the mouse lung: effects of elastase treatment.

Ito S, Ingenito EP, Arold SP, Parameswaran H, Tgavalekos NT, Lutchen KR, Suki B.

J Appl Physiol (1985). 2004 Jul;97(1):204-12. Epub 2004 Mar 12.


Minimum intensity anticoagulation therapy as primary prevention strategy.

Lankipalli R, Parameswaran H, Chemiti G.

Arch Intern Med. 2001 Apr 9;161(7):1015-6. No abstract available.


Supplemental Content

Loading ...
Support Center