Sort by
Items per page

Send to

Choose Destination

Search results

Items: 19


Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunity.

Tam EM, Fulton RB, Sampson JF, Muda M, Camblin A, Richards J, Koshkaryev A, Tang J, Kurella V, Jiao Y, Xu L, Zhang K, Kohli N, Luus L, Hutto E, Kumar S, Lulo J, Paragas V, Wong C, Suchy J, Grabow S, Dugast AS, Zhang H, Depis F, Feau S, Jakubowski A, Qiao W, Craig G, Razlog M, Qiu J, Zhou Y, Marks JD, Croft M, Drummond DC, Raue A.

Sci Transl Med. 2019 Oct 2;11(512). pii: eaax0720. doi: 10.1126/scitranslmed.aax0720.


Predicting ligand-dependent tumors from multi-dimensional signaling features.

Hass H, Masson K, Wohlgemuth S, Paragas V, Allen JE, Sevecka M, Pace E, Timmer J, Stelling J, MacBeath G, Schoeberl B, Raue A.

NPJ Syst Biol Appl. 2017 Sep 20;3:27. doi: 10.1038/s41540-017-0030-3. eCollection 2017.


Systems biology driving drug development: from design to the clinical testing of the anti-ErbB3 antibody seribantumab (MM-121).

Schoeberl B, Kudla A, Masson K, Kalra A, Curley M, Finn G, Pace E, Harms B, Kim J, Kearns J, Fulgham A, Burenkova O, Grantcharova V, Yarar D, Paragas V, Fitzgerald J, Wainszelbaum M, West K, Mathews S, Nering R, Adiwijaya B, Garcia G, Kubasek B, Moyo V, Czibere A, Nielsen UB, MacBeath G.

NPJ Syst Biol Appl. 2017 Jan 5;3:16034. doi: 10.1038/npjsba.2016.34. eCollection 2017. Review.


Single-cell quantitative HER2 measurement identifies heterogeneity and distinct subgroups within traditionally defined HER2-positive patients.

Onsum MD, Geretti E, Paragas V, Kudla AJ, Moulis SP, Luus L, Wickham TJ, McDonagh CF, MacBeath G, Hendriks BS.

Am J Pathol. 2013 Nov;183(5):1446-1460. doi: 10.1016/j.ajpath.2013.07.015. Epub 2013 Sep 11.


Computational modeling of ERBB2-amplified breast cancer identifies combined ErbB2/3 blockade as superior to the combination of MEK and AKT inhibitors.

Kirouac DC, Du JY, Lahdenranta J, Overland R, Yarar D, Paragas V, Pace E, McDonagh CF, Nielsen UB, Onsum MD.

Sci Signal. 2013 Aug 13;6(288):ra68. doi: 10.1126/scisignal.2004008. Erratum in: Sci Signal. 2014 Sep 30;7(345):er5.


Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.

McDonagh CF, Huhalov A, Harms BD, Adams S, Paragas V, Oyama S, Zhang B, Luus L, Overland R, Nguyen S, Gu J, Kohli N, Wallace M, Feldhaus MJ, Kudla AJ, Schoeberl B, Nielsen UB.

Mol Cancer Ther. 2012 Mar;11(3):582-93. doi: 10.1158/1535-7163.MCT-11-0820. Epub 2012 Jan 16.


Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.

Schoeberl B, Pace EA, Fitzgerald JB, Harms BD, Xu L, Nie L, Linggi B, Kalra A, Paragas V, Bukhalid R, Grantcharova V, Kohli N, West KA, Leszczyniecka M, Feldhaus MJ, Kudla AJ, Nielsen UB.

Sci Signal. 2009 Jun 30;2(77):ra31. doi: 10.1126/scisignal.2000352.


Purification and characterization of a recombinant version of human alpha-fetoprotein expressed in the milk of transgenic goats.

Parker MH, Birck-Wilson E, Allard G, Masiello N, Day M, Murphy KP, Paragas V, Silver S, Moody MD.

Protein Expr Purif. 2004 Dec;38(2):177-83.


GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells.

Anandasabapathy N, Ford GS, Bloom D, Holness C, Paragas V, Seroogy C, Skrenta H, Hollenhorst M, Fathman CG, Soares L.

Immunity. 2003 Apr;18(4):535-47.


The ELF -97 phosphatase substrate provides a sensitive, photostable method for labelling cytological targets.

Paragas VB, Kramer JA, Fox C, Haugland RP, Singer VL.

J Microsc. 2002 May;206(Pt 2):106-19.


CD4(+)CD25(+) T cells facilitate the induction of T cell anergy.

Ermann J, Szanya V, Ford GS, Paragas V, Fathman CG, Lejon K.

J Immunol. 2001 Oct 15;167(8):4271-5.


Immunization with DNA encoding an immunodominant peptide of insulin prevents diabetes in NOD mice.

Urbanek-Ruiz I, Ruiz PJ, Paragas V, Garren H, Steinman L, Fathman CG.

Clin Immunol. 2001 Aug;100(2):164-71.


The ELF-97 alkaline phosphatase substrate provides a bright, photostable, fluorescent signal amplification method for FISH.

Paragas VB, Zhang YZ, Haugland RP, Singer VL.

J Histochem Cytochem. 1997 Mar;45(3):345-57.


Fluorescence-based signal amplification technology.

Singer VL, Paragas VB, Larison KD, Wells KS, Fox CJ, Haugland RP.

Am Biotechnol Lab. 1994 Oct;12(11):55-6, 58. Review.


Simultaneous visualization of G- and F-actin in endothelial cells.

Haugland RP, You W, Paragas VB, Wells KS, DuBose DA.

J Histochem Cytochem. 1994 Mar;42(3):345-50.


A novel fluorogenic substrate for detecting alkaline phosphatase activity in situ.

Huang Z, You W, Haugland RP, Paragas VB, Olson NA, Haugland RP.

J Histochem Cytochem. 1993 Feb;41(2):313-7.


The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides.

Danska JS, Livingstone AM, Paragas V, Ishihara T, Fathman CG.

J Exp Med. 1990 Jul 1;172(1):27-33.

Supplemental Content

Loading ...
Support Center