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Items: 19


Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells.

Paquet-Fifield S, Koh SL, Cheng L, Beyit LM, Shembrey C, Mølck C, Behrenbruch C, Papin M, Gironella M, Guelfi S, Nasr R, Grillet F, Prudhomme M, Bourgaux JF, Castells A, Pascussi JM, Heriot AG, Puisieux A, Davis MJ, Pannequin J, Hill AF, Sloan EK, Hollande F.

Cancer Res. 2018 Jun 1;78(11):2925-2938. doi: 10.1158/0008-5472.CAN-17-1869. Epub 2018 Mar 6.


Surgical stress response and promotion of metastasis in colorectal cancer: a complex and heterogeneous process.

Behrenbruch C, Shembrey C, Paquet-Fifield S, Mølck C, Cho HJ, Michael M, Thomson BNJ, Heriot AG, Hollande F.

Clin Exp Metastasis. 2018 Apr;35(4):333-345. doi: 10.1007/s10585-018-9873-2. Epub 2018 Jan 15. Review.


Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

Williams SP, Odell AF, Karnezis T, Farnsworth RH, Gould CM, Li J, Paquet-Fifield S, Harris NC, Walter A, Gregory JL, Lamont SF, Liu R, Takano EA, Nowell CJ, Bower NI, Resnick D, Smyth GK, Coultas L, Hogan BM, Fox SB, Mueller SN, Simpson KJ, Achen MG, Stacker SA.

Sci Signal. 2017 Oct 3;10(499). pii: eaal2987. doi: 10.1126/scisignal.aal2987.


The fibrinolysis inhibitor α2-antiplasmin restricts lymphatic remodelling and metastasis in a mouse model of cancer.

Paquet-Fifield S, Roufail S, Zhang YF, Sofian T, Byrne DJ, Coughlin PB, Fox SB, Stacker SA, Achen MG.

Growth Factors. 2017 Jun;35(2-3):61-75. doi: 10.1080/08977194.2017.1349765. Epub 2017 Jul 11.


Differential Receptor Binding and Regulatory Mechanisms for the Lymphangiogenic Growth Factors Vascular Endothelial Growth Factor (VEGF)-C and -D.

Davydova N, Harris NC, Roufail S, Paquet-Fifield S, Ishaq M, Streltsov VA, Williams SP, Karnezis T, Stacker SA, Achen MG.

J Biol Chem. 2016 Dec 30;291(53):27265-27278. doi: 10.1074/jbc.M116.736801. Epub 2016 Nov 16.


High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells.

Xie J, Mølck C, Paquet-Fifield S, Butler L; Australian Prostate Cancer Bioresource, Sloan E, Ventura S, Hollande F.

Oncotarget. 2016 Jul 12;7(28):44492-44504. doi: 10.18632/oncotarget.9876.


VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury.

Sato T, Paquet-Fifield S, Harris NC, Roufail S, Turner DJ, Yuan Y, Zhang YF, Fox SB, Hibbs ML, Wilkinson-Berka JL, Williams RA, Stacker SA, Sly PD, Achen MG.

J Pathol. 2016 Jun;239(2):152-61. doi: 10.1002/path.4708. Epub 2016 Mar 30.


Mutated but Not Deleted Ovine PrP(C) N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic Mice.

Khalifé M, Reine F, Paquet-Fifield S, Castille J, Herzog L, Vilotte M, Moudjou M, Moazami-Goudarzi K, Makhzami S, Passet B, Andréoletti O, Vilette D, Laude H, Béringue V, Vilotte JL.

J Virol. 2015 Nov 25;90(3):1638-46. doi: 10.1128/JVI.02805-15. Print 2016 Feb 1.


Intestinal-specific activatable Myb initiates colon tumorigenesis in mice.

Malaterre J, Pereira L, Putoczki T, Millen R, Paquet-Fifield S, Germann M, Liu J, Cheasley D, Sampurno S, Stacker SA, Achen MG, Ward RL, Waring P, Mantamadiotis T, Ernst M, Ramsay RG.

Oncogene. 2016 May 12;35(19):2475-84. doi: 10.1038/onc.2015.305. Epub 2015 Aug 24.


Tumour but not stromal expression of β3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer.

Carter RZ, Micocci KC, Natoli A, Redvers RP, Paquet-Fifield S, Martin AC, Denoyer D, Ling X, Kim SH, Tomasin R, Selistre-de-Araújo H, Anderson RL, Pouliot N.

J Pathol. 2015 Apr;235(5):760-72. doi: 10.1002/path.4490. Epub 2015 Jan 7.


Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy.

Devaud C, Westwood JA, John LB, Flynn JK, Paquet-Fifield S, Duong CP, Yong CS, Pegram HJ, Stacker SA, Achen MG, Stewart TJ, Snyder LA, Teng MW, Smyth MJ, Darcy PK, Kershaw MH.

Mol Ther. 2014 Jan;22(1):18-27. doi: 10.1038/mt.2013.219. Epub 2013 Sep 19.


Vascular endothelial growth factor-d modulates caliber and function of initial lymphatics in the dermis.

Paquet-Fifield S, Levy SM, Sato T, Shayan R, Karnezis T, Davydova N, Nowell CJ, Roufail S, Ma GZ, Zhang YF, Stacker SA, Achen MG.

J Invest Dermatol. 2013 Aug;133(8):2074-84. doi: 10.1038/jid.2013.83. Epub 2013 Feb 25.


The propeptides of VEGF-D determine heparin binding, receptor heterodimerization, and effects on tumor biology.

Harris NC, Davydova N, Roufail S, Paquet-Fifield S, Paavonen K, Karnezis T, Zhang YF, Sato T, Rothacker J, Nice EC, Stacker SA, Achen MG.

J Biol Chem. 2013 Mar 22;288(12):8176-86. doi: 10.1074/jbc.M112.439299. Epub 2013 Feb 12.


Remodeling of the lymphatic vasculature during mouse mammary gland morphogenesis is mediated via epithelial-derived lymphangiogenic stimuli.

Betterman KL, Paquet-Fifield S, Asselin-Labat ML, Visvader JE, Butler LM, Stacker SA, Achen MG, Harvey NL.

Am J Pathol. 2012 Dec;181(6):2225-38. doi: 10.1016/j.ajpath.2012.08.035. Epub 2012 Oct 11.


Functional characterization of quiescent keratinocyte stem cells and their progeny reveals a hierarchical organization in human skin epidermis.

Schlüter H, Paquet-Fifield S, Gangatirkar P, Li J, Kaur P.

Stem Cells. 2011 Aug;29(8):1256-68. doi: 10.1002/stem.675.


A transplant model for human epidermal skin regeneration.

Paquet-Fifield S, Redvers RP, Pouliot N, Kaur P.

Methods Mol Biol. 2010;585:369-82. doi: 10.1007/978-1-60761-380-0_26.


A role for pericytes as microenvironmental regulators of human skin tissue regeneration.

Paquet-Fifield S, Schlüter H, Li A, Aitken T, Gangatirkar P, Blashki D, Koelmeyer R, Pouliot N, Palatsides M, Ellis S, Brouard N, Zannettino A, Saunders N, Thompson N, Li J, Kaur P.

J Clin Invest. 2009 Sep;119(9):2795-806. doi: 10.1172/JCI38535. Epub 2009 Aug 3.


E2F7 can regulate proliferation, differentiation, and apoptotic responses in human keratinocytes: implications for cutaneous squamous cell carcinoma formation.

Endo-Munoz L, Dahler A, Teakle N, Rickwood D, Hazar-Rethinam M, Abdul-Jabbar I, Sommerville S, Dickinson I, Kaur P, Paquet-Fifield S, Saunders N.

Cancer Res. 2009 Mar 1;69(5):1800-8. doi: 10.1158/0008-5472.CAN-08-2725. Epub 2009 Feb 17. Erratum in: Cancer Res. 2009 Sep 1;69(17):7130.


Establishment of 3D organotypic cultures using human neonatal epidermal cells.

Gangatirkar P, Paquet-Fifield S, Li A, Rossi R, Kaur P.

Nat Protoc. 2007;2(1):178-86.


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