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Items: 1 to 50 of 81

1.

The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice.

Engle DD, Tiriac H, Rivera KD, Pommier A, Whalen S, Oni TE, Alagesan B, Lee EJ, Yao MA, Lucito MS, Spielman B, Da Silva B, Schoepfer C, Wright K, Creighton B, Afinowicz L, Yu KH, Grützmann R, Aust D, Gimotty PA, Pollard KS, Hruban RH, Goggins MG, Pilarsky C, Park Y, Pappin DJ, Hollingsworth MA, Tuveson DA.

Science. 2019 Jun 21;364(6446):1156-1162. doi: 10.1126/science.aaw3145.

PMID:
31221853
2.

Muller's Ratchet and Ribosome Degeneration in the Obligate Intracellular Parasites Microsporidia.

Melnikov SV, Manakongtreecheep K, Rivera KD, Makarenko A, Pappin DJ, Söll D.

Int J Mol Sci. 2018 Dec 19;19(12). pii: E4125. doi: 10.3390/ijms19124125.

3.

DPM-1001 decreased copper levels and ameliorated deficits in a mouse model of Wilson's disease.

Krishnan N, Felice C, Rivera K, Pappin DJ, Tonks NK.

Genes Dev. 2018 Jul 1;32(13-14):944-952. doi: 10.1101/gad.314658.118. Epub 2018 Jun 26.

4.

Error-prone protein synthesis in parasites with the smallest eukaryotic genome.

Melnikov SV, Rivera KD, Ostapenko D, Makarenko A, Sanscrainte ND, Becnel JJ, Solomon MJ, Texier C, Pappin DJ, Söll D.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6245-E6253. doi: 10.1073/pnas.1803208115. Epub 2018 Jun 18.

5.

Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells.

Naguib A, Mathew G, Reczek CR, Watrud K, Ambrico A, Herzka T, Salas IC, Lee MF, El-Amine N, Zheng W, Di Francesco ME, Marszalek JR, Pappin DJ, Chandel NS, Trotman LC.

Cell Rep. 2018 Apr 3;23(1):58-67. doi: 10.1016/j.celrep.2018.03.032.

6.

Proteomic profile of cystic fibrosis sputum cells in adults chronically infected with Pseudomonas aeruginosa.

Pattison SH, Gibson DS, Johnston E, Peacock S, Rivera K, Tunney MM, Pappin DJ, Elborn JS.

Eur Respir J. 2017 Jul 5;50(1). pii: 1601569. doi: 10.1183/13993003.01569-2016. Print 2017 Jul.

7.

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

Chio IIC, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, Wilkinson JE, Buscaglia JM, DeNicola GM, Tiriac H, Hammell M, Crawford HC, Schmidt EE, Thompson CB, Pappin DJ, Sonenberg N, Tuveson DA.

Cell. 2016 Aug 11;166(4):963-976. doi: 10.1016/j.cell.2016.06.056. Epub 2016 Jul 28.

8.

Confirmation of translatability and functionality certifies the dual endothelin1/VEGFsp receptor (DEspR) protein.

Herrera VL, Steffen M, Moran AM, Tan GA, Pasion KA, Rivera K, Pappin DJ, Ruiz-Opazo N.

BMC Mol Biol. 2016 Jun 14;17(1):15. doi: 10.1186/s12867-016-0066-8.

9.

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.

Shen C, Ipsaro JJ, Shi J, Milazzo JP, Wang E, Roe JS, Suzuki Y, Pappin DJ, Joshua-Tor L, Vakoc CR.

Mol Cell. 2015 Dec 17;60(6):847-59. doi: 10.1016/j.molcel.2015.10.033. Epub 2015 Nov 25.

10.

Efficient Reassignment of a Frequent Serine Codon in Wild-Type Escherichia coli.

Ho JM, Reynolds NM, Rivera K, Connolly M, Guo LT, Ling J, Pappin DJ, Church GM, Söll D.

ACS Synth Biol. 2016 Feb 19;5(2):163-71. doi: 10.1021/acssynbio.5b00197. Epub 2015 Nov 20.

11.

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.

Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, Pappin DJ, Dow LE, Papadopoulos N, Gross SS, Cantley LC.

Science. 2015 Dec 11;350(6266):1391-6. doi: 10.1126/science.aaa5004. Epub 2015 Nov 5.

12.

Differential connectivity of splicing activators and repressors to the human spliceosome.

Akerman M, Fregoso OI, Das S, Ruse C, Jensen MA, Pappin DJ, Zhang MQ, Krainer AR.

Genome Biol. 2015 Jun 6;16:119. doi: 10.1186/s13059-015-0682-5.

13.

BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia.

Roe JS, Mercan F, Rivera K, Pappin DJ, Vakoc CR.

Mol Cell. 2015 Jun 18;58(6):1028-39. doi: 10.1016/j.molcel.2015.04.011. Epub 2015 May 14.

14.

PTEN functions by recruitment to cytoplasmic vesicles.

Naguib A, Bencze G, Cho H, Zheng W, Tocilj A, Elkayam E, Faehnle CR, Jaber N, Pratt CP, Chen M, Zong WX, Marks MS, Joshua-Tor L, Pappin DJ, Trotman LC.

Mol Cell. 2015 Apr 16;58(2):255-68. doi: 10.1016/j.molcel.2015.03.011. Epub 2015 Apr 9.

15.

Organoid models of human and mouse ductal pancreatic cancer.

Boj SF, Hwang CI, Baker LA, Chio II, Engle DD, Corbo V, Jager M, Ponz-Sarvise M, Tiriac H, Spector MS, Gracanin A, Oni T, Yu KH, van Boxtel R, Huch M, Rivera KD, Wilson JP, Feigin ME, Öhlund D, Handly-Santana A, Ardito-Abraham CM, Ludwig M, Elyada E, Alagesan B, Biffi G, Yordanov GN, Delcuze B, Creighton B, Wright K, Park Y, Morsink FH, Molenaar IQ, Borel Rinkes IH, Cuppen E, Hao Y, Jin Y, Nijman IJ, Iacobuzio-Donahue C, Leach SD, Pappin DJ, Hammell M, Klimstra DS, Basturk O, Hruban RH, Offerhaus GJ, Vries RG, Clevers H, Tuveson DA.

Cell. 2015 Jan 15;160(1-2):324-38. doi: 10.1016/j.cell.2014.12.021. Epub 2014 Dec 31.

16.

p53 mutations change phosphatidylinositol acyl chain composition.

Naguib A, Bencze G, Engle DD, Chio II, Herzka T, Watrud K, Bencze S, Tuveson DA, Pappin DJ, Trotman LC.

Cell Rep. 2015 Jan 6;10(1):8-19. doi: 10.1016/j.celrep.2014.12.010. Epub 2014 Dec 24.

17.

A quantitative proteomics-based signature of platinum sensitivity in ovarian cancer cell lines.

Fan G, Wrzeszczynski KO, Fu C, Su G, Pappin DJ, Lucito R, Tonks NK.

Biochem J. 2015 Feb 1;465(3):433-42. doi: 10.1042/BJ20141087.

18.

Dephosphorylation of tyrosine 393 in argonaute 2 by protein tyrosine phosphatase 1B regulates gene silencing in oncogenic RAS-induced senescence.

Yang M, Haase AD, Huang FK, Coulis G, Rivera KD, Dickinson BC, Chang CJ, Pappin DJ, Neubert TA, Hannon GJ, Boivin B, Tonks NK.

Mol Cell. 2014 Sep 4;55(5):782-90. doi: 10.1016/j.molcel.2014.07.018. Epub 2014 Aug 28.

19.

A tool to evaluate correspondence between extraction ion chromatographic peaks and peptide-spectrum matches in shotgun proteomics experiments.

Ruse CI, Peacock S, Ghiban C, Rivera K, Pappin DJ, Leopold P.

Proteomics. 2013 Aug;13(16):2386-97. doi: 10.1002/pmic.201300022. Epub 2013 Jul 11.

20.

H2S-Induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response.

Krishnan N, Fu C, Pappin DJ, Tonks NK.

Sci Signal. 2011 Dec 13;4(203):ra86. doi: 10.1126/scisignal.2002329.

21.

Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila.

Haase AD, Fenoglio S, Muerdter F, Guzzardo PM, Czech B, Pappin DJ, Chen C, Gordon A, Hannon GJ.

Genes Dev. 2010 Nov 15;24(22):2499-504. doi: 10.1101/gad.1968110. Epub 2010 Oct 21.

22.

Computational protein profile similarity screening for quantitative mass spectrometry experiments.

Kirchner M, Renard BY, Köthe U, Pappin DJ, Hamprecht FA, Steen H, Steen JA.

Bioinformatics. 2010 Jan 1;26(1):77-83. doi: 10.1093/bioinformatics/btp607. Epub 2009 Oct 27.

PMID:
19861354
23.

Straightforward and de novo peptide sequencing by MALDI-MS/MS using a Lys-N metalloendopeptidase.

Boersema PJ, Taouatas N, Altelaar AF, Gouw JW, Ross PL, Pappin DJ, Heck AJ, Mohammed S.

Mol Cell Proteomics. 2009 Apr;8(4):650-60. doi: 10.1074/mcp.M800249-MCP200. Epub 2008 Nov 29.

24.

Electron transfer dissociation of iTRAQ labeled peptide ions.

Han H, Pappin DJ, Ross PL, McLuckey SA.

J Proteome Res. 2008 Sep;7(9):3643-8. doi: 10.1021/pr8001113. Epub 2008 Jul 23.

25.

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.

Zhang Y, Wolf-Yadlin A, Ross PL, Pappin DJ, Rush J, Lauffenburger DA, White FM.

Mol Cell Proteomics. 2005 Sep;4(9):1240-50. Epub 2005 Jun 11.

26.

Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents.

Ross PL, Huang YN, Marchese JN, Williamson B, Parker K, Hattan S, Khainovski N, Pillai S, Dey S, Daniels S, Purkayastha S, Juhasz P, Martin S, Bartlet-Jones M, He F, Jacobson A, Pappin DJ.

Mol Cell Proteomics. 2004 Dec;3(12):1154-69. Epub 2004 Sep 22.

27.

Suppression of alpha-cyano-4-hydroxycinnamic acid matrix clusters and reduction of chemical noise in MALDI-TOF mass spectrometry.

Smirnov IP, Zhu X, Taylor T, Huang Y, Ross P, Papayanopoulos IA, Martin SA, Pappin DJ.

Anal Chem. 2004 May 15;76(10):2958-65.

PMID:
15144210
28.

The Secreted Larval Acidic Proteins (SLAPs) of Onchocerca spp. are encoded by orthologues of the alt gene family of Brugia malayi and have host protective potential.

Wu Y, Egerton G, Pappin DJ, Harrison RA, Wilkinson MC, Underwood A, Bianco AE.

Mol Biochem Parasitol. 2004 Apr;134(2):213-24.

PMID:
15003841
29.

The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation.

Diao A, Rahman D, Pappin DJ, Lucocq J, Lowe M.

J Cell Biol. 2003 Jan 20;160(2):201-12. Epub 2003 Jan 21.

30.

Peptide mass fingerprinting using MALDI-TOF mass spectrometry.

Pappin DJ.

Methods Mol Biol. 2003;211:211-9. No abstract available.

PMID:
12489433
31.

Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach.

Ragno S, Romano M, Howell S, Pappin DJ, Jenner PJ, Colston MJ.

Immunology. 2001 Sep;104(1):99-108.

32.

The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis.

Corrigall VM, Bodman-Smith MD, Fife MS, Canas B, Myers LK, Wooley P, Soh C, Staines NA, Pappin DJ, Berlo SE, van Eden W, van Der Zee R, Lanchbury JS, Panayi GS.

J Immunol. 2001 Feb 1;166(3):1492-8.

33.

Proteomics: new perspectives, new biomedical opportunities.

Banks RE, Dunn MJ, Hochstrasser DF, Sanchez JC, Blackstock W, Pappin DJ, Selby PJ.

Lancet. 2000 Nov 18;356(9243):1749-56. Review.

PMID:
11095271
34.

Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice.

Perraudeau M, Taylor PR, Stauss HJ, Lindstedt R, Bygrave AE, Pappin DJ, Ellmerich S, Whitten A, Rahman D, Canas B, Walport MJ, Botto M, Altmann DM.

Eur J Immunol. 2000 Oct;30(10):2871-80.

35.

Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization.

Navaratnam DS, Fernando FS, Priddle JD, Giles K, Clegg SM, Pappin DJ, Craig I, Smith AD.

J Neurochem. 2000 May;74(5):2146-53.

36.

Probability-based protein identification by searching sequence databases using mass spectrometry data.

Perkins DN, Pappin DJ, Creasy DM, Cottrell JS.

Electrophoresis. 1999 Dec;20(18):3551-67.

PMID:
10612281
37.

Direct interaction between p47phox and protein kinase C: evidence for targeting of protein kinase C by p47phox in neutrophils.

Reeves EP, Dekker LV, Forbes LV, Wientjes FB, Grogan A, Pappin DJ, Segal AW.

Biochem J. 1999 Dec 15;344 Pt 3:859-66. Erratum in: Biochem J 2000 Feb 1;345 Pt 3:767.

38.

Thymosin beta 4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoids.

Young JD, Lawrence AJ, MacLean AG, Leung BP, McInnes IB, Canas B, Pappin DJ, Stevenson RD.

Nat Med. 1999 Dec;5(12):1424-7.

PMID:
10581087
39.

Molecular characterization of a human DNA kinase.

Karimi-Busheri F, Daly G, Robins P, Canas B, Pappin DJ, Sgouros J, Miller GG, Fakhrai H, Davis EM, Le Beau MM, Weinfeld M.

J Biol Chem. 1999 Aug 20;274(34):24187-94.

40.

A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein.

Höss M, Robins P, Naven TJ, Pappin DJ, Sgouros J, Lindahl T.

EMBO J. 1999 Jul 1;18(13):3868-75.

41.

Re-evaluation of the primary structure of Ralstonia eutropha phasin and implications for polyhydroxyalkanoic acid granule binding.

Hanley SZ, Pappin DJ, Rahman D, White AJ, Elborough KM, Slabas AR.

FEBS Lett. 1999 Mar 19;447(1):99-105.

42.

Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis.

Lowe M, Rabouille C, Nakamura N, Watson R, Jackman M, Jämsä E, Rahman D, Pappin DJ, Warren G.

Cell. 1998 Sep 18;94(6):783-93.

43.

HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading.

van Ham SM, Tjin EP, Lillemeier BF, Grüneberg U, van Meijgaarden KE, Pastoors L, Verwoerd D, Tulp A, Canas B, Rahman D, Ottenhoff TH, Pappin DJ, Trowsdale J, Neefjes J.

Curr Biol. 1997 Dec 1;7(12):950-7.

44.

Qa-1 interaction and T cell recognition of the Qa-1 determinant modifier peptide.

Cotterill LA, Stauss HJ, Millrain MM, Pappin DJ, Rahman D, Canas B, Chandler P, Stackpoole A, Simpson E, Robinson PJ, Dyson PJ.

Eur J Immunol. 1997 Sep;27(9):2123-32.

PMID:
9341749
45.

Peptide mass fingerprinting using MALDI-TOF mass spectrometry.

Pappin DJ.

Methods Mol Biol. 1997;64:165-73. No abstract available.

PMID:
9116819
46.

A monoclonal antibody, 3/22, to rabbit CD11c which induces homotypic T cell aggregation: evidence that ICAM-1 is a ligand for CD11c/CD18.

Blackford J, Reid HW, Pappin DJ, Bowers FS, Wilkinson JM.

Eur J Immunol. 1996 Mar;26(3):525-31.

PMID:
8605916
47.

PRK1 phosphorylates MARCKS at the PKC sites: serine 152, serine 156 and serine 163.

Palmer RH, Schönwasser DC, Rahman D, Pappin DJ, Herget T, Parker PJ.

FEBS Lett. 1996 Jan 15;378(3):281-5.

48.

Identification of phosphorylation sites in the mouse oestrogen receptor.

Lahooti H, White R, Hoare SA, Rahman D, Pappin DJ, Parker MG.

J Steroid Biochem Mol Biol. 1995 Dec;55(3-4):305-13.

PMID:
8541227
49.

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