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Items: 50

1.

In vivo elongation of thin filaments results in heart failure.

Mi-Mi L, Farman GP, Mayfield RM, Strom J, Chu M, Pappas CT, Gregorio CC.

PLoS One. 2020 Jan 3;15(1):e0226138. doi: 10.1371/journal.pone.0226138. eCollection 2020.

2.

Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy.

Ahrens-Nicklas RC, Pappas CT, Farman GP, Mayfield RM, Larrinaga TM, Medne L, Ritter A, Krantz ID, Murali C, Lin KY, Berger JH, Yum SW, Carreon CK, Gregorio CC.

Sci Adv. 2019 Sep 4;5(9):eaax2066. doi: 10.1126/sciadv.aax2066. eCollection 2019 Sep.

3.

Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics.

Ly T, Pappas CT, Johnson D, Schlecht W, Colpan M, Galkin VE, Gregorio CC, Dong WJ, Kostyukova AS.

Mol Biol Cell. 2019 Jan 15;30(2):268-281. doi: 10.1091/mbc.E18-06-0406. Epub 2018 Nov 21.

4.

Cardiac-specific knockout of Lmod2 results in a severe reduction in myofilament force production and rapid cardiac failure.

Pappas CT, Farman GP, Mayfield RM, Konhilas JP, Gregorio CC.

J Mol Cell Cardiol. 2018 Sep;122:88-97. doi: 10.1016/j.yjmcc.2018.08.009. Epub 2018 Aug 11.

5.

HSPB7 is indispensable for heart development by modulating actin filament assembly.

Wu T, Mu Y, Bogomolovas J, Fang X, Veevers J, Nowak RB, Pappas CT, Gregorio CC, Evans SM, Fowler VM, Chen J.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11956-11961. doi: 10.1073/pnas.1713763114. Epub 2017 Oct 23.

6.

The N-terminal tropomyosin- and actin-binding sites are important for leiomodin 2's function.

Ly T, Moroz N, Pappas CT, Novak SM, Tolkatchev D, Wooldridge D, Mayfield RM, Helms G, Gregorio CC, Kostyukova AS.

Mol Biol Cell. 2016 Aug 15;27(16):2565-75. doi: 10.1091/mbc.E16-03-0200. Epub 2016 Jun 15.

7.

Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin.

Kolb J, Li F, Methawasin M, Adler M, Escobar YN, Nedrud J, Pappas CT, Harris SP, Granzier H.

J Mol Cell Cardiol. 2016 Aug;97:286-94. doi: 10.1016/j.yjmcc.2016.04.013. Epub 2016 Apr 30.

8.

Mutation-specific effects on thin filament length in thin filament myopathy.

Winter JM, Joureau B, Lee EJ, Kiss B, Yuen M, Gupta VA, Pappas CT, Gregorio CC, Stienen GJ, Edvardson S, Wallgren-Pettersson C, Lehtokari VL, Pelin K, Malfatti E, Romero NB, Engelen BG, Voermans NC, Donkervoort S, Bönnemann CG, Clarke NF, Beggs AH, Granzier H, Ottenheijm CA.

Ann Neurol. 2016 Jun;79(6):959-69. doi: 10.1002/ana.24654. Epub 2016 Apr 30.

9.

Nebulin, a multi-functional giant.

Chu M, Gregorio CC, Pappas CT.

J Exp Biol. 2016 Jan;219(Pt 2):146-52. doi: 10.1242/jeb.126383. Review.

10.

Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality.

Pappas CT, Mayfield RM, Henderson C, Jamilpour N, Cover C, Hernandez Z, Hutchinson KR, Chu M, Nam KH, Valdez JM, Wong PK, Granzier HL, Gregorio CC.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13573-8. doi: 10.1073/pnas.1508273112. Epub 2015 Oct 20.

11.

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy.

Yuen M, Sandaradura SA, Dowling JJ, Kostyukova AS, Moroz N, Quinlan KG, Lehtokari VL, Ravenscroft G, Todd EJ, Ceyhan-Birsoy O, Gokhin DS, Maluenda J, Lek M, Nolent F, Pappas CT, Novak SM, D'Amico A, Malfatti E, Thomas BP, Gabriel SB, Gupta N, Daly MJ, Ilkovski B, Houweling PJ, Davidson AE, Swanson LC, Brownstein CA, Gupta VA, Medne L, Shannon P, Martin N, Bick DP, Flisberg A, Holmberg E, Van den Bergh P, Lapunzina P, Waddell LB, Sloboda DD, Bertini E, Chitayat D, Telfer WR, Laquerrière A, Gregorio CC, Ottenheijm CA, Bönnemann CG, Pelin K, Beggs AH, Hayashi YK, Romero NB, Laing NG, Nishino I, Wallgren-Pettersson C, Melki J, Fowler VM, MacArthur DG, North KN, Clarke NF.

J Clin Invest. 2015 Jan;125(1):456-7. doi: 10.1172/JCI80057. Epub 2015 Jan 2. No abstract available.

12.

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy.

Yuen M, Sandaradura SA, Dowling JJ, Kostyukova AS, Moroz N, Quinlan KG, Lehtokari VL, Ravenscroft G, Todd EJ, Ceyhan-Birsoy O, Gokhin DS, Maluenda J, Lek M, Nolent F, Pappas CT, Novak SM, D'Amico A, Malfatti E, Thomas BP, Gabriel SB, Gupta N, Daly MJ, Ilkovski B, Houweling PJ, Davidson AE, Swanson LC, Brownstein CA, Gupta VA, Medne L, Shannon P, Martin N, Bick DP, Flisberg A, Holmberg E, Van den Bergh P, Lapunzina P, Waddell LB, Sloboda DD, Bertini E, Chitayat D, Telfer WR, Laquerrière A, Gregorio CC, Ottenheijm CA, Bönnemann CG, Pelin K, Beggs AH, Hayashi YK, Romero NB, Laing NG, Nishino I, Wallgren-Pettersson C, Melki J, Fowler VM, MacArthur DG, North KN, Clarke NF.

J Clin Invest. 2014 Nov;124(11):4693-708. doi: 10.1172/JCI75199. Epub 2014 Sep 24. Erratum in: J Clin Invest. 2015 Jan;125(1):456-7.

13.

Deleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function.

Granzier HL, Hutchinson KR, Tonino P, Methawasin M, Li FW, Slater RE, Bull MM, Saripalli C, Pappas CT, Gregorio CC, Smith JE 3rd.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14589-94. doi: 10.1073/pnas.1411493111. Epub 2014 Sep 22.

14.

Gamma knife radiosurgery for recurrent glossopharyngeal neuralgia after microvascular decompression.

Stanic S, Franklin SD, Pappas CT, Stern RL.

Stereotact Funct Neurosurg. 2012;90(3):188-91. doi: 10.1159/000338089. Epub 2012 Jun 5.

PMID:
22678456
15.

Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization.

Donlin LT, Andresen C, Just S, Rudensky E, Pappas CT, Kruger M, Jacobs EY, Unger A, Zieseniss A, Dobenecker MW, Voelkel T, Chait BT, Gregorio CC, Rottbauer W, Tarakhovsky A, Linke WA.

Genes Dev. 2012 Jan 15;26(2):114-9. doi: 10.1101/gad.177758.111. Epub 2012 Jan 12.

16.

Predictors of HVOT performance in Parkinson's disease.

Higginson CI, Wheelock VL, Levine D, Pappas CT, Sigvardt KA.

Appl Neuropsychol. 2011 Jul;18(3):210-5. doi: 10.1080/09084282.2011.595447.

17.

The Nebulin family: an actin support group.

Pappas CT, Bliss KT, Zieseniss A, Gregorio CC.

Trends Cell Biol. 2011 Jan;21(1):29-37. doi: 10.1016/j.tcb.2010.09.005. Epub 2010 Oct 15. Review.

18.

Leiomodin-2 is an antagonist of tropomodulin-1 at the pointed end of the thin filaments in cardiac muscle.

Tsukada T, Pappas CT, Moroz N, Antin PB, Kostyukova AS, Gregorio CC.

J Cell Sci. 2010 Sep 15;123(Pt 18):3136-45. doi: 10.1242/jcs.071837. Epub 2010 Aug 24.

19.

Nebulin regulates actin filament lengths by a stabilization mechanism.

Pappas CT, Krieg PA, Gregorio CC.

J Cell Biol. 2010 May 31;189(5):859-70. doi: 10.1083/jcb.201001043. Epub 2010 May 24.

20.

Reduced myofibrillar connectivity and increased Z-disk width in nebulin-deficient skeletal muscle.

Tonino P, Pappas CT, Hudson BD, Labeit S, Gregorio CC, Granzier H.

J Cell Sci. 2010 Feb 1;123(Pt 3):384-91. doi: 10.1242/jcs.042234. Epub 2010 Jan 5.

21.

The option of Linac-based radiosurgery in a Gamma Knife radiosurgery center.

Stern RL, Perks JR, Pappas CT, Boggan JE, Chen AY.

Clin Neurol Neurosurg. 2008 Dec;110(10):968-72. doi: 10.1016/j.clineuro.2008.05.023. Epub 2008 Jul 9.

PMID:
18617321
22.

The clinical significance of neuropsychological changes following bilateral subthalamic nucleus deep brain stimulation for Parkinson's disease.

Higginson CI, Wheelock VL, Levine D, King DS, Pappas CT, Sigvardt KA.

J Clin Exp Neuropsychol. 2009 Jan;31(1):65-72. doi: 10.1080/13803390801982734. Epub 2008 May 19.

PMID:
18608676
23.

Cognitive deficits in essential tremor consistent with frontosubcortical dysfunction.

Higginson CI, Wheelock VL, Levine D, King DS, Pappas CT, Sigvardt KA.

J Clin Exp Neuropsychol. 2008 Oct;30(7):760-5. doi: 10.1080/13803390701754738. Epub 2008 Feb 15.

PMID:
18608666
24.

Nebulin interacts with CapZ and regulates thin filament architecture within the Z-disc.

Pappas CT, Bhattacharya N, Cooper JA, Gregorio CC.

Mol Biol Cell. 2008 May;19(5):1837-47. doi: 10.1091/mbc.E07-07-0690. Epub 2008 Feb 13.

25.

Transposable element orientation bias in the Drosophila melanogaster genome.

Cutter AD, Good JM, Pappas CT, Saunders MA, Starrett DM, Wheeler TJ.

J Mol Evol. 2005 Dec;61(6):733-41. Epub 2005 Nov 2.

PMID:
16315105
26.

Temporal evolution of oscillations and synchrony in GPi/muscle pairs in Parkinson's disease.

Hurtado JM, Rubchinsky LL, Sigvardt KA, Wheelock VL, Pappas CT.

J Neurophysiol. 2005 Mar;93(3):1569-84. Epub 2004 Oct 20.

27.

Construction and validation of the Rhodobacter sphaeroides 2.4.1 DNA microarray: transcriptome flexibility at diverse growth modes.

Pappas CT, Sram J, Moskvin OV, Ivanov PS, Mackenzie RC, Choudhary M, Land ML, Larimer FW, Kaplan S, Gomelsky M.

J Bacteriol. 2004 Jul;186(14):4748-58.

28.

Impact of collimator leaf width on stereotactic radiosurgery and 3D conformal radiotherapy treatment plans.

Kubo HD, Wilder RB, Pappas CT.

Int J Radiat Oncol Biol Phys. 1999 Jul 1;44(4):937-45.

PMID:
10386653
29.

A comparison of arc-based and static mini-multileaf collimator-based radiosurgery treatment plans.

Kubo HD, Pappas CT, Wilder RB.

Radiother Oncol. 1997 Oct;45(1):89-93.

PMID:
9364637
30.

Epilepsy surgery for hippocampal sclerosis.

Pappas CT.

West J Med. 1993 Jan;158(1):71. No abstract available.

31.

Outcome analysis in 654 surgically treated lumbar disc herniations.

Pappas CT, Harrington T, Sonntag VK.

Neurosurgery. 1992 Jun;30(6):862-6.

PMID:
1614587
32.
33.

Iatrogenic arteriovenous fistula presenting as a recurrent subdural hematoma. Case report.

Pappas CT, Zabramski JM, Shetter AG.

J Neurosurg. 1992 Jan;76(1):134-6.

PMID:
1727151
34.

Surgical decisions regarding medically intractable epilepsy.

Spencer DD, Pappas CT.

Clin Neurosurg. 1992;38:548-66. Review.

PMID:
1537203
35.

Combined approach for lesions involving the cerebellopontine angle and skull base: experience with 20 cases--preliminary report.

Daspit CP, Spetzler RF, Pappas CT.

Otolaryngol Head Neck Surg. 1991 Dec;105(6):788-96.

PMID:
1787968
36.
37.
38.
39.

Management of anterior skull base tumors.

Spetzler RF, Pappas CT.

Clin Neurosurg. 1991;37:490-501. Review.

PMID:
2009703
40.

Cruciate paralysis: a clinical and radiographic analysis of injuries to the cervicomedullary junction.

Dickman CA, Hadley MN, Pappas CT, Sonntag VK, Geisler FH.

J Neurosurg. 1990 Dec;73(6):850-8. Review.

PMID:
2230968
41.

Extracerebral cavernous angiomas of the middle fossa.

Rigamonti D, Pappas CT, Spetzler RF, Johnson PC.

Neurosurgery. 1990 Aug;27(2):306-10.

PMID:
2385350
42.

Anatomical evaluation of the caudal regression syndrome (lumbosacral agenesis) with magnetic resonance imaging.

Pappas CT, Seaver L, Carrion C, Rekate H.

Neurosurgery. 1989 Sep;25(3):462-5.

PMID:
2771018
43.

Signet-ring cell lymphoma of the central nervous system. Case report.

Pappas CT, Johnson PC, Sonntag VK.

J Neurosurg. 1988 Nov;69(5):789-92.

PMID:
3183739
44.

Lumbar stenosis in the elderly.

Sonntag V, Pappas CT.

West J Med. 1988 Sep;149(3):324-5. No abstract available.

45.
46.
47.

Effect of prolonged exposure to 80% oxygen on the lung of the newborn mouse.

Pappas CT, Obara H, Bensch KG, Northway WH Jr.

Lab Invest. 1983 Jun;48(6):735-48.

PMID:
6855196
48.

A study of the ultrastructure of the organs and of cultured fibroblasts incubated with isoleucine from a patient with propionic acidemia.

Kott-Blumenkranz R, Pappas CT, Bensch KG.

Hum Pathol. 1981 Dec;12(12):1141-8. No abstract available.

PMID:
7333577
49.

Morphological changes in the cerebral cortex of rats with altered levels of ovarian hormones.

Pappas CT, Diamond MC, Johnson RE.

Behav Neural Biol. 1979 Jul;26(3):298-310. No abstract available.

PMID:
486027
50.

Effects of ovariectomy and differential experience on rat cerebral cortical morphology.

Pappas CT, Diamond MC, Johnson RE.

Brain Res. 1978 Oct 6;154(1):53-60. No abstract available.

PMID:
698821

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